• Journal of Korean society of Dental Hygiene
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• v.22 no.1
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• pp.29-36
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• 2022

Objectives: This study aimed to examine the association between age at menarche and two major oral diseases. Methods: Data from the 7th Korean National Health and Nutrition Examination Survey (2016-2018) were used. The participants included girls and women aged 12 years and above. Thedataofa total of 7,420 participants were analyzed. Statistical analyses were performed using complex samples cross-tabulation analysis and complex samples general linear model. Results: The average age at menarche of those aged 12 to 80 years was 13.81 years. The age at menarche was found to be associated with decayed-missing-filled teeth (DMFT) (p<0.05). When the age at menarche was nine years, DMFT was 4.20 when it was 19 years, DMFT was 10.80. The age at menarche was found to be associated with periodontal tissue state (p<0.05). The group with early menarche age had healthier periodontal tissues (17.1%), whereas the group with late menarche age had more unhealthy periodontal tissues (17.9%) (p<0.001). Conclusions: The age at menarche was associated with two major oral diseases. Therefore, it is necessary to provide women with oral hygiene care and oral health education to prevent major oral diseases before their secondary sex characteristics appear.

• Journal of Oral Medicine and Pain
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• v.34 no.2
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• pp.133-141
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• 2009

We reviewed retrospectively the medical records of 600 elderly patients, over 65 years old who visited oral medicine. The ratio of the age group was composed of 65${\sim}$74 years old group was 63.7%, 75${\sim}$84 years old group was 32.2%, over 85years old group was 4.2%, and the patients were mostly females. The main chief complaint was composed of oral soft tissue problem(44.1%) and oromaxillofacial pain(39.0%). The majority of systemic diseases was composed of diseases of the circulatory system(30.1%), diseases of the musculoskeletal system and connective tissue(16.8%), endocrine, nutritional and metabolic diseases, and diseases of the digestive system(10.1%). The numerous pateints were diagnosed as soft tissue disease(32.0%), arthrogenous disease(24.1%), and myogenous disease(18.1%) of temporomandibular disease.Principally medication(43.9%), physical therapy(24.2%) were performed. 14.2% of all patients visited oral medicine with a letter of request written by other medical departments or local dental clinics, or referred from other departments in Chosun university dental hospital. These findings indicate epidemiologic characteristics on the elderly patients visited oral medicine. We hope that this study will play a basis in the future research about the elderly patients.

• Journal of Korean society of Dental Hygiene
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• v.16 no.3
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• pp.383-390
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• 2016

Objectives: The purpose of this study was to examine the correlation between oral malodor and related factors in visitors to preventive dentistry practice lab. Methods: The subjects were selected from 71 visitors to preventive dentistry practice lab in a department of dental hygiene. The subjects were from twenty to twenty nine years old and had no systemic diseases or symptoms. The questionnaire consisted of general characteristics, oral malodor concentration, oral health status, oral health behavior, and self-rated oral malodor. Results: The mean concentration of the oral cavity gas was 50.80. The score of 50.80 was a weak smell by the selected judgement criteria. The oral malodor prevalence rate accounted for 39.1 percent and a weak smell was detected in 40 points. Those having higher oral malodor concentration tended to have lower self-rated oral health status(p<0.05). Conclusions: The results can not be generalized to determine the cause of oral malodor, but self-rated oral health status can be linked to systemic disease control. More investigation should be taken in order to analyzed the correlation between oral malodor and systemic diseases.

• Journal of Oral Medicine and Pain
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• v.35 no.4
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• pp.229-235
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• 2010

A common method for treating oral mucosal diseases is taking medication by oral administration. The oral administration is the method of least resistance. Because large part of drugs is degraded by liver, it is necessary to take more drugs getting to appropriate level in blood stream. And there are so many side effects when patients take drugs by oral administration. In so many cases, the patients who suffer from oral mucosal problems have the other general diseases simultaneously. Willingly or not, some patients can't take the medicine by oral administration. Number of topical drugs for oral mucosal disease is less than that for skin diseases because the environment of oral mucosa prevents activity of medicine. In this paper, research on effects of topical type medication for treating oral mucosal diseases is conducted through investigating currently used medications and their effects. In addition, effects of dissolved oral medications with appropriate solvent are demonstrated if this medication is useful for patients clinically.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.8
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• pp.4621-4625
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• 2013

The purpose of this study was to construct a protein-protein interaction (PPI) network related to oral squamous cell carcinoma (OSCC). Each protein was ranked and those most associated with OSCC were mined within the network. First, OSCC-related genes were retrieved from the Online Mendelian Inheritance in Man (OMIM) database. Then they were mapped to their protein identifiers and a seed set of proteins was built. The seed proteins were expanded using the nearest neighbor expansion method to construct a PPI network through the Online Predicated Human Interaction Database (OPHID). The network was verified to be statistically significant, the score of each protein was evaluated by algorithm, then the OSCC-related proteins were ranked. 38 OSCC related seed proteins were expanded to 750 protein pairs. A protein-protein interaction nerwork was then constructed and the 30 top-ranked proteins listed. The four highest-scoring seed proteins were SMAD4, CTNNB1, HRAS, NOTCH1, and four non-seed proteins P53, EP300, SMAD3, SRC were mined using the nearest neighbor expansion method. The methods shown here may facilitate the discovery of important OSCC proteins and guide medical researchers in further pertinent studies.

• Journal of Convergence for Information Technology
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• v.7 no.5
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• pp.67-73
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• 2017

To investigate the perception of the correlation between systemic diseases and oral health among some university students. The questionnaires were conducted on 485 students from 3 universities in Gwangju. As a result of the study, the female was higher than the male and was the highest in the fourth grade. Subjective health status, drinking status, smoking experience, and exercise were not significantly different in recognizing the association between systemic disease and oral health. The group with experience in oral health education recognized 3.18, and the group that practiced educational contents was highly recognized as 3.21. There was a significant difference between the two groups. Multiple regression analysis showed that major factor and grade factor influenced the perception of association between systemic disease and oral health. Therefore, it is necessary for university students to recognize the importance and necessity of periodical oral examinations. It is thought that the incidence of disease should be strengthened and enforced to recognize that there is a correlation with various diseases.

• Journal of dental hygiene science
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• v.19 no.4
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• pp.228-237
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• 2019

Background: This study aimed to investigate allergic rhinitis and the relationship between allergic diseases, such as asthma and allergic rhinitis, and dental caries and periodontal disease using the raw data from third year of the 6th Korean National Health and Nutrition Examination Survey. Methods: A total of 3,729 subjects aged over 30 years who underwent examination for allergic diseases and an oral health checkup were selected. The data were analyzed using SPSS IBM SPSS ver. 25.0 (IBM Corp., USA). Composite sample cross correlation and composite sample logistic regression analyses were performed using the composite sample general linear model. Results: On examining the socioeconomic characteristics of the subjects suffering from allergic disease and the relationship between allergic disease and oral health, allergic rhinitis was more frequently found in younger subjects with a higher level of education. Periodontal disease and dental caries were more frequent among female, older age groups, lower income earners, and subjects with a lower level of education (p<0.05). On examining the relationship between the oral health characteristics of the subject and allergic diseases and oral health, allergic rhinitis was more common in subjects with a good oral health status perception than those who answered "bad" to the oral health status question. The community periodontal index of treatment needs (CPITN) score was higher in subjects who answered "poor" to the oral health status question, lower frequency of brushing, and higher in subjects using secondary oral hygiene products; the decayed, missing and filled teeth (DMFT) index was higher in subjects with a perception of poor oral health status (p<0.05). The DMFT index was high in the asthma group, and the CPITN score was high in the group who answered "no" to allergic rhinitis. Conclusion: There is a relationship between asthma and allergic rhinitis and the DFMT index and CPITN score. Corresponding oral programs for allergic patients need to be developed.

• Journal of Oral Medicine and Pain
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• v.37 no.2
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• pp.75-79
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• 2012

Helicobacter pylori(H. pylori) associated with gastritis and gastric cancer is mainly detected dental plaque and saliva in the oral cavity. Most infection is probably acquired in childhood, but the route of transmission is not clear. The oral cavity has been indicated as secondary reservoir of H. pylori, and may therefore be argued in the route of transmission and reinfection of the stomach which follows treatment of H. pylori infection. So this review aimed to discuss about H. pylori in the oral cavity. H. pylori in stomach can appear in the oral cavity by gastroesophageal reflex or vomiting, but infection of stomach and oral cavity is different. Diagnostic methods are serological method, urea breath test, PCR method, urease test, histologic method and so on. Nested PCR recommend for detection of H. pylori in saliva and dental plaque. H. pylori infection in the oral cavity appear variously and is no relation with dental diseases. The antimicrobial mouthrinse recommend in patients with periodontal diseases because of high detection rate fo H. pylori. Thus H. pylori may be considered as the normal oral microflora.

• Journal of dental hygiene science
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• v.23 no.4
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• pp.302-311
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• 2023

Background: Oral health is an important element of well aging. And oral health also affects overall health, mental health, and quality of life. In this study, we sought to identify oral health influencing factors and research trends for well-aging through text analysis of research on well-aging and oral health over the past 12 years. Methods: The research data was analyzed based on English literature published in PubMed from 2012 to 2023. Aging well and oral health were used as search terms, and 115 final papers were selected. Network text analysis included keyword frequency analysis, centrality analysis, and cohesion structure analysis using the Net-Miner 4.0 program. Results: Excluding general characteristics, the most frequent keywords in 115 articles, 520 keywords (Mesh terms) were psychology, dental prosthesis and Alzheimer's disease, Dental caries, cognition, cognitive dysfunction, and bacteria. Research keywords with high degree centrality were Dental caries (0.864), Quality of life (0.833), Tooth loss (0.818), Health status (0.727), and Life expectancy (0.712). As a result of community analysis, it consisted of 4 groups. Group 1 consisted of chewing and nutrition, Group 2 consisted oral diseases, systemic diseases and management, Group 3 consisted oral health and mental health, Group 4 consisted oral frailty symptoms and quality of life. Conclusion: In an aging society, oral dysfunction affects mental health and quality of life. Preventing oral diseases for well-aging can have a positive impact on mental health and quality of life. Therefore, efforts are needed to prevent oral frailty in a super-aging society by developing and educating systematic oral care programs for each life cycle.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.49 no.5
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• pp.241-242
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• 2023