• 한국치위생학회지
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• 제16권6호
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• pp.1093-1104
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• 2016

Objectives: The purpose of this study was to examine the impact of chronic disease on oral health behavior. Methods: The subjects were 317 adults over 30-years old living in urban and rural areas. They were selected by convenience sampling method and filled out the self-reported questionnaire. The questionnaire consisted of general characteristics, dental treatment, chronic disease, and oral health behavior including oral health self-care behavior and professional oral health care. Results: The self-care oral health behavior and the professional oral health care had a negative correlation with the chronic diseases. Especially, the self-care oral health behavior and the professional oral health care had a statistically significant negative correlation with hypertension and osteoporosis. Multiple regression analysis was performed after including general characteristics, dental treatment, chronic disease. Meanwhile the presence of chronic disease had a significant influence on the self-care oral health behavior and the professional oral health care. Hypertension and Osteoporosis were the most influential factors of chronic diseases and had a significant influence on the oral health behavior. In conclusion, the chronic diseases aggravated the oral health behavior practice. Conclusions: presence of chronic disease affects oral health behavior. Therefore, the effective intervention and education programs related to oral health care are necessary to enhance adult's oral health behavior and total health. The continuous follow-up study will determine the causal relationship between oral health behavior and the presence of chronic disease.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.6227-6232
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• 2012

Interleukin-4 receptor (IL-4R) gene single nucleotide polymorphisms (SNPs) are implicated in cancer development. However, results from the published reports have remained inconclusive. The objective of this study was to conduct a meta-analysis investigating the association between polymorphisms in IL-4R gene and cancer risk. Pubmed, EMBASE and China National Knowledge Infrastructure (CNKI) were searched for case-control studies published up to October 30, 2012 that investigated IL-4R polymorphisms and cancer risk. Odds ratios (ORs) and 95% confidence intervals (CIs) were used to evaluate the strength of any associations. Three IL-4R polymorphisms (Q576R, rs1801275; I75V, rs1805010; S503P, rs1805015) in 21 case-control studies were analyzed. Our meta-analysis indicated that these three polymorphisms are not associated with cancer risk when all studies were pooled together. In the subgroup analysis by tumor site, the results showed that Q576R G allele carriers were associated with a significantly decreased cervical cancer risk (recessive model: OR = 0.77, 95%CI = 0.60-0.98; homozygote comparison: OR = 0.76, 95%CI = 0.58-0.98). I75V G allele carriers were associated with a decreased risk of renal cancer (dominant model = 0.71, 95%CI = 0.57-0.89, heterozygote comparison: OR = 0.69, 95%CI = 0.55-0.87). When stratified by ethnicity, Q576R G allele carriers were associated with a decreased cancer risk in Caucasians (dominant model: OR = 0.90, 95%CI = 0.83-0.98; heterozygote comparison: OR = 0.89, 95%CI = 0.82-0.98). I75V G allele carriers were associated with a decreased cancer risk in Asians (heterozygote comparison: OR = 0.76, 95%CI = 0.62-0.94). S503P C allele carriers were also associated with a decreased cancer risk in Asians (CC VS TT: OR = 0.29, 95%CI = 0.08-0.99). Our results suggest that Q576R, I75V and S503P may be associated with a decreased cancer risk for certain types of cancers and in some specific ethnic groups. Future case-control studies with large sample size are needed to evaluate these associations in detail.

• Imaging Science in Dentistry
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• 제48권3호
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• pp.161-165
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• 2018

Purpose: To evaluate the usefulness of shear wave elastography in the diagnosis of oral and maxillofacial diseases. Materials and Methods: Ten patients with oral and maxillofacial diseases and 28 volunteers drawn from our student doctors were examined by shear wave elastography with a 14-MHz linear transducer using an Aplio 300 apparatus (Canon Medical Systems, Otawara, Japan). A statistical analysis of the shear elastic modulus(kPa) of healthy tissue (the sublingual gland, submandibular gland, anterior belly of the digastric muscle, and geniohyoid muscle) in the 28 volunteers was performed using 1-way repeated measures analysis of variance with the Tukey honest significant difference test. The maximum shear elastic modulus(kPa) of 8 patients with squamous cell carcinoma (SCC) and 2 patients with benign lesions was evaluated with the Mann-Whitney U test. The analysis used a 5% significance level. Results: The mean shear elastic modulus of the sublingual gland ($9.4{\pm}3.7kPa$) was lower than that of the geniohyoid muscle ($19.2{\pm}9.2kPa$, P=.000) and the anterior belly of the digastric muscle ($15.3{\pm}6.1kPa$, P=.004). The maximum shear elastic modulus of the SCCs($109.6{\pm}14.4kPa$) was higher than that of the benign lesions($46.4{\pm}26.8kPa$, P=.044). Conclusion: Our results demonstrated the usefulness of shear wave elastography in the diagnosis of oral and maxillofacial diseases. Shear wave elastography has the potential to be an effective technique for the objective and quantitative diagnosis of oral and maxillofacial diseases.

• 치위생과학회지
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• 제17권1호
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• pp.12-19
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• 2017

인구사회학적 특성과 건강행태 및 스트레스 정도에 따른 만성질환과 구강건강의 연관성에 대한 인식도에 차이가 있는지를 알아보고자 20대부터 50대까지의 성인을 대상으로 분석하여, 다음과 같은 결론을 얻었다. 연구대상자의 만성 질환과 구강건강과의 연관성에 대한 인식도는 구강건강과 당뇨와의 연관성이 3.29로 가장 높게 인식하고 있었으며, 고혈압과의 연관성은 2.82로 가장 낮은 인식도를 보였다. 특히 '항고혈압제 약의 부작용으로 구강건조증, 잇몸출혈, 치유지연, 잇몸비대 등이 나타날 수 있다'라는 항목은 전체 항목에서 1.52로 가장 낮은 인식도로 나타났다. 인구사회학적특성에 따른 만성질환과 구강건강과의 연관성에 대한 인식도를 분석한 결과 직업에 따른 인식도 차이는 통계적으로 유의하였는데 공무원, 전문직 집단에서 가장 높은 인식도를 보였다(p=0.015). 이상의 연구 결과를 종합해볼 때 만성질환과 구강건강의 연관성에 대한 일반인들의 인식을 전환시켜야 할 필요성이 있으며, 치과진료실에서는 구강보건교육시 단순한 구강건강관리뿐만 아니라 통합적인 건강관리의 방향으로 만성질환을 포함한 전신과 구강건강과의 연관성에 대한 교육을 강화하여 수행할 필요성이 있을 것으로 판단된다.

• 한국치위생학회지
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• 제15권6호
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• pp.947-961
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• 2015

Objectives: The purpose of the study was to identify the relationship between metabolic syndrome and oral diseases in the middle aged and elderly in Korea. Methods: The study subjects were 6,390 people over 40 years old from 2010 and 2012 Korea National Health and Nutrition Examination Survey. The survey questionnaire consisted of health, nutrition, and oral examination surveys. The independent variables included general characteristics, health behavior, oral health behavior, and metabolic syndrome. The dependent variables included dental caries experience and periodontal disease. The oral examination was carried out by the dentist based on World Health Organization standard. Results: The average prevalence rate of metabolic syndrome MS was 23.79%, including 54.84% of risk group and 21.37% of normal group. The missing teeth rate was 82.38%, DMFT rate was 90.28% and the periodontal disease rate was 33.15%. Those having abnormal fasting blood glucose had 1.17 fold(95% CI: 1.00~1.37) higher periodontal disease than the normal group. The abnormal HDL cholesterol group had 1.25 times higher odds ratio(95% CI: 1.07~1.46) and the obese group had 1.27 times higher odds ratio(95% CI: 1.07~1.51). The risk group had 1.20 times higher odds ration(95% CI: 1.00~1.44) and that of the metabolic syndrome group was 1.60 times higher(95% CI: 1.29~1.97) in periodontal disease. The high blood pressure group had 1.25 times of missing teeth prevalence rate(95% CI: 1.00~1.37). The metabolic syndrome group had 1.47 times of missing teeth prevalence rate(95% CI: 1.11~1.94). Conclusions: The middle aged and elderly people in Korea had higher rate of metabolic syndrome and oral disease. It is necessary to implement the preventive oral health examination for the control of metabolic syndrome and oral diseases prevalence.

• 한국치위생학회지
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• 제12권6호
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• pp.1250-1259
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• 2012

Objectives : TThe purpose of this study was to examine the relationship between the oral health education experience of workers and their oral health awareness in an attempt to provide some information on corporate oral health education plans. Methods : The, subjects in this study were 230 workers in Busan and South Gyeongsang Province, on whom a self-administered survey was conducted from August, 2010, to June 18, 2011. A frequency analysis was carried out to grasp the general characteristics of the 205 respondents, and x2-test(p). Results : 1. As for the relationship of the oral health education experience of the workers and their awareness of toothbrush involving optimum toothbrush size, 47.4 percent of those without educational experience thought that a toothbrush should be large enough to cover about two teeth(p<.018). 2. Regarding the relationship between the oral health education experience of the workers and their awareness of fluoride, 59.1 percent of the respondents with educational experience perceived that dentifrice contained fluoride(p<.05). 3. Concerning the relationship between the oral health education experience of the workers and their awareness of periodontal diseases including the cause of the diseases, 43.6 percent of the respondents with educational experience(p<.021). 4. As to the relationship between the oral health education experience of the workers and their awareness of scaling, 50.2 percent of the respondents with educational experience and gingival diseases(p<.037). 5. In terms of the relationship between the oral health education experience of the workers and their awareness of toothbrushing involving toothbrushing frequency, 36.8 percent of those without it considered it necessary to do toothbrushing three times a day(p<.045). Conclusions : The above-mentioned findings illustrated that there were differences among the workers in oral health awareness according to their oral health education experience. Therefore the development of systematic oral health education programs is required to promote the oral health of workers.

• Clinical and Experimental Pediatrics
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• 제54권1호
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• pp.6-10
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• 2011

Many patients assume that allergic reactions against foods are responsible for triggering or worsening their allergic symptoms. Therefore, it is important to identify patients who would benefit from an elimination diet, while avoiding unnecessary dietary restrictions. The diagnosis of food allergy depends on the thorough review of the patients's medical history, results of supplemented trials of dietary elimination, and in vivo and in vitro tests for measuring specific IgE levels. However, in some cases the reliability of such procedures is suboptimal. Oral food challenges are procedures employed for making an accurate diagnosis of immediate and occasionally delayed adverse reactions to foods. The timing and type of the challenge, preparation of patients, foods to be tested, and dosing schedule should be determined on the basis of the patient's history, age, and experience. Although double-blind, placebo-controlled food challenges(DBPCFC) are used to establish definitively if a food is the cause of adverse reactions, they are time-consuming, expensive and troublesome for physician and patients. In practice, An open challenge controlled by trained personnel is sufficient especially in infants and young children. The interpretation of the results and follow-up after a challenge are also important. Since theses challenges are relatively safe and informative, controlled oral food challenges could become the measure of choice in children.

• 한국산학기술학회논문지
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• 제15권9호
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• pp.5675-5682
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• 2014

구강질환은 단독 진행만이 아닌 혼합감염증으로 발생하므로 치아우식증 및 치주질환에 관여하는 원인 균주들의 명확한 분석이 필요하다. 이에, 본 연구는 치아우식증 및 치주질환의 원인균으로 잘 알려져 있는 세균을 검출하기 위해 타액을 채취하였다. 성인의 연령, 흡연 및 음주, 질병유무에 따른 구강세균분포 차이를 보고 구강세균의 위험요소를 확인하고자 한다. 본 연구 대상은 20대 이상 65세 미만 성인 120명을 대상으로 2014년 3월 15일 - 5월 10일까지 조사하였다. 타액 내 gDNA를 추출 후 PCR 방법을 이용하여 구강질환의 균 분포도를 확인하였다. 그 결과, S. mutans는 72명, P. intermedia 88명, S. mutans와 P. intermedia 균이 모두 검출된 성인은 54명, 구강세균이 검출되지 않은 성인은 14명으로 나타났다. 구강세균의 위험 요소 결과, 흡연자는 비흡연자에 비해 S. mutans 2.8배, P. intermedia 3.5배 더 높게 나타났다. 음주자는 비음주자에 비해 S. mutans 검출 위험도가 3.3배 더 높은 것으로 나타났으며, 전신질환자는 정상인에 비해 P. intermedia 검출된 위험도가 4.1배 더 높은 것으로 나타났다. 흡연, 음주, 전신질환은 구강 내 세균 검출위험도가 높은 인자임을 확인할 수 있었다. 또한 연령이 증가할수록 치주질환 세균이 더 많이 검출되었으며, 20대는 치아우식증과 치주질환이 공존하는 연령대인 만큼 구강세균의 분포가 더 두드러지게 나타남을 알 수 있었다. 구강세균이 검출된 성인은 치아우식증과 치주질환에 이환될 위험도가 그만큼 높다고 볼 수 있으므로, 구강환경을 청결히하고 정기적인 치과방문을 통해 구강질환을 예방해야 할 것이다.

• 한국치위생학회지
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• 제15권4호
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• pp.727-733
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• 2015

Objectives: The purpose of the study is to investigate the awareness toward oral health and plaque removal in the elderly people in Korea. Methods: An interview method was carried out to 308 elderly people from a senior welfare facility in Mokpo, Jeonnam from May 1 to December 30, 2011 after receiving informed consents. Except 4 incomplete answers, data were analyzed using SPSS 18.0 program. The questionnaire consisted of demographical characteristics of the subjects, experience of plaque removal, recognition towards plaque removal, and correlation to systemic diseases. Results: Most of the elderly people experiences plaque removal(63.4%) and 55.9% had revisit intention. Those having plaque removal accounted for 47.8% and they had good subjective oral health recognition. Those not having plaque removal accounted for 61.8% and 61.8% having average systemic health condition and 53.3% having poor oral health recognition. The plaque removal was closely related to subjective oral health recognition. Conclusions: It is necessary to develop the preventive oral health program for the elderly people. The plaque removal in the elderly people is the most important services to prevent the systemic diseases including hypertension, arthritis, diabetes, nervous disease, and gastrointestinal diseases.

• 한국치위생학회지
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• 제22권1호
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• pp.29-36
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• 2022

Objectives: This study aimed to examine the association between age at menarche and two major oral diseases. Methods: Data from the 7th Korean National Health and Nutrition Examination Survey (2016-2018) were used. The participants included girls and women aged 12 years and above. Thedataofa total of 7,420 participants were analyzed. Statistical analyses were performed using complex samples cross-tabulation analysis and complex samples general linear model. Results: The average age at menarche of those aged 12 to 80 years was 13.81 years. The age at menarche was found to be associated with decayed-missing-filled teeth (DMFT) (p<0.05). When the age at menarche was nine years, DMFT was 4.20 when it was 19 years, DMFT was 10.80. The age at menarche was found to be associated with periodontal tissue state (p<0.05). The group with early menarche age had healthier periodontal tissues (17.1%), whereas the group with late menarche age had more unhealthy periodontal tissues (17.9%) (p<0.001). Conclusions: The age at menarche was associated with two major oral diseases. Therefore, it is necessary to provide women with oral hygiene care and oral health education to prevent major oral diseases before their secondary sex characteristics appear.