• Title/Summary/Keyword: optimum dosage

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Effects of Ionizing Radiation on Sprout Inhibition and Nutritive Value of Potato Tubers (방사선(放射線) 조사(照射)가 감자 괴경(塊莖)의 맹아억제(萌芽抑制) 및 영양가(營養價)에 미치는 영향(影響))

  • Lee, Mie-Soon;Kim, Hong-Lyour
    • Korean Journal of Food Science and Technology
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    • v.4 no.1
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    • pp.29-35
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    • 1972
  • Effects of various dosages of gamma ray ranging from 0 to 16 krad on sprout inhibition and nutritive value of potato tubers were investigated with Irish Cobbler variety. Sprout growth was gradually suppressed with increasing dosage, and completely inhibited with 16 krad treatment. Under this optimum dosage, weight loss of tubers was markedly reduced and tubers kept firm throughout the 2 month storage period. Irradiation had no adverse effects on the cooking quality of potato tubers. Moisture content of stored potato tubers was shown to be in inverse proportion to sprout growth. Tubers treated with 16 krad tended to contain somewhat higher percentage of total carbohydrate than those treated with lower dosages. Significantly larger amounts of ascorbic acid were retained in 8 and 16 krad treatments than in 0 and 2 krad treatments.

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Development of Yeast Strains as Feed for Aquaculture: Possible Yeast Strains (양식을 위한 먹이사료로서의 Yeast 균주의 개발: 가능성 있는 효모 균주)

  • 문정혜;탁건태;김중균
    • Journal of Life Science
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    • v.6 no.2
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    • pp.135-141
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    • 1996
  • Possible yeast strains that could be used as feed for aquaculture were studied. It was shown that the maximum specific growth rate and the biomass yield of Kluyveromyces fragilis yeast and Candida utilis yeast under optimum pH and temperature were much higher than those of Saccharomyces cervisiae yeast which had been as established yeast diet for rotifer culture. Hence, this work was focussed on the growth characteristics of the two yeasts through flask dultures for mass production. With 5% inoculum dosage, the best values of $\mu$$_{max}$ and OD$_{max}$ were obtained with on 2.5% fructose medium and 2% YE medium for K. fragilis and C. utilis, respectively, where the values of $\mu$$_{max}$ and OD$_{max}$ were found to be 0.73 hr$^{-1}$ and 3.00 for K. fragilis and 0.59 hr$^{-1}$ and 2.80 for C. utilis. It was also found that the lag phase of the growth incresed with increasing initial zinc and NaCl concentrations and decreased with increasing inoculum dosage. Both yeasts could survive relatively well at 3.5% NaCl concentration, and only C. utilis yeast could utilize zinc.

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Formulation and Pharmacokinetic Evaluation of Sustained Release Preparation Containing Clebopride Malate (말산클레보프리드 서방성 제제의 제조 및 약물동태학적 평가)

  • Ryou, Hae-Won;Lee, Joo-Han;Chi, Yong-Ha;Hahn, Yang-Hee;Tan, Hyun-Kwang;Lee, Kyu-Heung;Kim, Sang-Lin;Jeon, Seung-Yoon;Choi, Young-Wook
    • Journal of Pharmaceutical Investigation
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    • v.30 no.3
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    • pp.179-189
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    • 2000
  • Clebopride malate(Cm) is a new benzamide drug which has a potent central antidopaminergic activity possessing antiemetic and anxiolytic properties. A purpose of this study was to assess the feasibility of formulating sustained release preparation by dispersing a drug in hydrophilic polymeric matrices and double layered tablets(DLT), using HPMC, carbopol, PEO, PVP/VA and other polymers as a rate controlling barrier. The matrix and DLT showed optimum dissolution pattern up to 8 hours and the contents of polymer were optimized at 30% level in this preparation. After an oral administration in beagle dog, Cm concentration was determined by use of GC-ECD and pharmacokinetic parameters were calculated by Vallner's method. The AUC of DLT showed similar results and the duration of action was increased 55% compared to that of regular release dosage form. The calculated absorption rate effectiveness(ARE) and controlled release effectiveness(CRE) for DLT increased 50% compared to that of matrix, the overall effectiveness(E) of this product appears to be about 70%. in vivo effectiveness test, DLT showed significant differences from control on antiemetic action of Cm. In consequence, it was possible to conclude that double layered tablet might be a good candidate for the sustained release dosage forms.

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Comparison of Flocculation Characteristics of Humic Acid by Inorganic and Organic Coagulants: Effects of pH and Ionic Strength

  • Xu Mei-Lan;Lee Min-Gyu;Kam Sang-Kyu
    • Journal of Environmental Science International
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    • v.14 no.8
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    • pp.723-737
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    • 2005
  • The effects of pH (5, 7 and 9) and ionic strength of different salts on the flocculation characteristics of humic acid by inorganic (alum, polyaluminum chloride (PAC) with degree of neutralization, r=(OH/Al) of 1.7) and organic (cationic polyelectrolyte) coagulants, have been examined using a simple continuous optical technique, coupled with measurements of zeta potential. The results are compared mainly by the mechanisms of its destabilization and subsequent removal. The destabilization and subsequent removal of humic acid by PAC and cationic polyelectrolyte occur by a simple charge neutralization, regardless of pH of the solution. However, the mechanism of those by alum is greatly dependent on pH and coagulant dosage, i.e., both mechanisms of charge neutralization at lower dosages and sweep flocculation at higher dosages at pH 5, by sweep flocculation mechanism at pH 7, and little flocculation because of electrostatic repulsion between negatively charged humic acid and aluminum species at pH 9. The ionic strength also affects those greatly, mainly based on the charge of salts, and so is more evident for the salts of highly charged cationic species, such as $CaCl_2$ and $MgCI_2.$ However, it is found that the salts have no effect on those at the optimum dosage for alum acting by the mechanism of sweep flocculation at pH 7, regardless of their charge.

Change of Characteristics during Organic Liquid Fertilizer Processing using Ascidian Tunic (우렁쉥이 껍질을 이용한 유기 액비 제조시 발효액의 특성 변화)

  • Ryoo, Jae-Hwan
    • Korean Journal of Organic Agriculture
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    • v.22 no.4
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    • pp.683-693
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    • 2014
  • This study was carried out to investigate the characteristics of the organic liquid fertilizer and find out optimum fermentation conditions of Effective Microorganisms (EM) including ascidian tunic. During the EM fermentation by adding ascidian tunic, electrical conductivity (EC) was increased, contrast to decrease the pH value, on related to the initial dosage molasses rate. Additionally, the total nitrogen quantity was shown to be increased on EM fermentation and the most effective increasing was recorded up to 220% on more than 15% molasses dosage condition. The phosphorus quantity was to be maximum rate on 21th of EM fermentation, and other contents, such to potassium, calcium, magnesium, sodium, had be shown an increasing patten during the fermentation period. After the EM fermentation, the concentration of hazardous material (Zn, As, Cd, Cu, Cr, Hg, Ni, pb) was measured below than the official criteria for commercial fertilizer. As a effective material in fermentated fertilizer, the 29 kinds free amino acids were detected and their total concentration was measured to 7080.94 mg/L.

A novel nanocomposite as adsorbent for formaldehyde removal from aqueous solution

  • Hejri, Zahra;Hejri, Mehri;Omidvar, Maryam;Morshedi, Sadjad
    • Advances in nano research
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    • v.8 no.1
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    • pp.1-11
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    • 2020
  • In order to develop a new adsorbent for removal of formaldehyde from aqueous solution, surface modification of TiO2 nanoparticles was performed with 2,4-Dinitrophenylhydrazine (DNPH) that have a strong affinity to the formaldehyde. Sodium dodecyl sulfate (SDS) surfactant was used to improve the DNPH grafting to TiO2 surface. Modified adsorbents were characterized by SEM, TEM, XRD, EDX and FTIR. Since the COD level in wastewaters including formaldehyde is considerable, it is necessary to determine the COD content of the synthetic wastewater. In order to determine the optimal removal conditions, the effect of contact time (60-210 min), pH (4-10) and adsorbent dosage (0.5-1.5 g/L) on adsorption and COD removal efficiencies were studied, using response surface method. EDX and FTIR analysis confirmed the presence of nitrogen-containing functional groups on the modified TiO2 surface. The maximum formaldehyde adsorption and COD removal efficiencies by modified TiO2 were about 15.65 and 7.35% higher than the unmodified nanoparticles respectively. Therefore, the grafting of nano-TiO2 with DNPH would greatly improve its formaldehyde adsorption efficiency. The optimum conditions determined for a maximum formaldehyde removal of 99.904% and a COD reduction of 94.815% by TiO2/SDS/DNPH nanocomposites were: adsorbent dosage 1.100 g/L, pH 7.424 and the contact time 183.290 min.

Degradation of Reactive Black 5 by potassium ferrate(VI) (페레이트를 활용한 아조 염료 Reactive Black 5 분해 연구)

  • Minh Hoang Nguyen;Il-kyu Kim
    • Journal of Korean Society of Water and Wastewater
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    • v.38 no.1
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    • pp.17-27
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    • 2024
  • This paper aims to study the degradation process for refractory azo dye namely Reactive Black 5(RB5) by potassium ferrate(VI) synthesized using the wet oxidation method. The process of degradation of azo dyes by Ferrate was studied with several parameters such as pH, different Ferrate(VI) dosage, different azo dye initial concentration, and temperature. A second-order reaction was observed in all degradation processes for RB5 having the highest degradation efficiency. The highest kapp value of RB5 degradation was 190.49 M-1s-1. In the pH experiments, the neutral condition has been identified as the optimum condition for the degradation of RB5 with 63.2% of dye removal. The efficiency of degradation also depends on the amount of ferrate(VI) available in the reactor. Degradation efficiency increased with an increase in Potassium Ferrate(VI) dosage or a decrease of RB5 initial concentration. The temperature has been reported as one of the most important parameters. From the results, increasing the temperature(up to 45℃) will increase the degradation efficiency of azo dye by Ferrate(VI) and if the temperature exceeds 45℃, the degradation efficiency will be decreased.

Effective correlation between coagulation efficiency and the sludge settling characteristic (슬러지 응집효율이 침강특성에 미치는 상관관계에 대한 연구)

  • Han, Gee-Bong;Yoon, Ji-Hyun
    • Journal of the Korea Organic Resources Recycling Association
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    • v.14 no.1
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    • pp.151-159
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    • 2006
  • In these days, the importance of sludge treatment is emerging due to the London Convention, so this study was conducted to propose the alternatives for the improved sludge treatment on the organic wastewater and sewage sludge with JAR test and settling column equipped with stirrer. The minimum coagulant dosage to earn the optimum sludge settling efficiency resulted from 200mg/l and each critical sludge settling interface showed no distinct difference when PAC was dosed over 200mg/l. Accordingly, Clarification Rate(CR) with 200mg/l dosage was calculated to CR=(Ho-Ht) / Ho=1-0.4=0.6 because the critical sludge settling height stopped at 0.4. The settling velocity of sludge interface was decreased with the increase of MLSS concentration but rather increased with MLSS concentration over 1,000mg/l. This resulted from positive effect of interacted coagulation for floc formation by transfer to the zone of compressed settling when MLSS concentration increased over 1,000mg/l. The settling velocity of sludge interface showed $28.66{\times}10^{-3}/min$ for average settling velocity of sewage sludge which is 6.7 times higher than $4.25{\times}10^{-3}/min$ for average settling velocity of organic wastewater sludge. The increasing rate of CR for organic wastewater activated sludge was higher than that of settling velocity under 200mg/l of PAC dosage but settling velocity was higher than CR over 200mg/l of PAC dosage. However, in case of sewage sludge, the differential rate of CR was low when PAC dosage was increased but the settling velocity was suddenly increased with over 200mg/l dosage. Therefore coagulation effect was more efficient to MLSS settling velocity rather than SS removal effect in the supernatant.

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Formation Characteristics of $BDOC_{rapid}$ and $BDOC_{slow}$ by Ozonation (오존처리에 의한 $BDOC_{rapid}$$BDOC_{slow}$ 생성 특성)

  • Son, Hee-Jong;Jung, Chul-Woo;Choi, Young-Ik;Bae, Sang-Dae
    • Journal of Korean Society of Environmental Engineers
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    • v.28 no.12
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    • pp.1274-1279
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    • 2006
  • The formation characteristics of $BDOC_{rapid}$ and $BDOC_{slow}$ with different ozone dosages for 3 different kinds of waters from Maeri raw water in the down stream of Nakdong river, Hoidong reservoir water in Busan City and treated Maeri raw water(sand filtered) has been investigated in this study. The ozone dosages for producing maximum $BDOC_{total}$ in the Maeri raw water, Hoidong reservoir water and sand filtered water of Maeri were 0.9, 1.1 and 1.4 $mgO_3$/mgDOC respectively. It could be concluded that the ozone dosages for formations of maximum $BDOC_{total}$ were determined by characteristics of water. The ozone dosages for producing maximum $BDOC_{rapid}$ in the Maeri raw water, Hoidong reservoir water and sand filtered water of Maeri were 0.9, 0.9 and 1.0 $mgO_3$/mgDOC respectively that were same or lower than the used ozone dosages for producing maximum $BDOC_{total}$. $BDOC_{slow}$ was being formated and increased continuously with the higher ozone dosages which were the used ozone dosages for maximum formation of $BDOC_{total}$ and $BDOC_{rapid}$. For the best results of a pre-treatment of biofiltration, the optimum ozone dosage ranges in formation of $BDOC_{rapid}/BDOC_{total}$ were $0.6{\sim}1.0\;mgO_3$/mgDOC that were lower than the ozone dosage ranges of $0.9{\sim}1.4\;mgO_3$/mgDOC for the maximum formation $BDOC_{total}$. The reported results indicated that the best and effective ways from economic and technical points of view to determine the optimum ozone dosages of the pretreatment of biofilteration process were investigating and classifying BDOC.

A Practical Study on the Solid-Liquid Separation of the Swine Wastewater from Slurry Feedlot (슬러리 양돈분뇨의 최적 고액분리 방안 연구)

  • Park, Seung-Kyun;Choi, Jae-Gil;Chung, Yoon-Jin
    • Journal of the Korea Organic Resources Recycling Association
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    • v.8 no.2
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    • pp.60-70
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    • 2000
  • The swine wastewater from slurry feedlot has been a social problem in Korea since the proper treatment is very difficult. Therefore, a practical study on the Solid-Liquid separation of swine wastewater from slurry feedlot was carried out as a pan of pretreatment for the successful biological treatment. The appropriate type of coagulant and optimum dosage were proposed for the most efficient Solid-Liquid separation and the best Solid-Liquid separation methods for different size of feedlot were determined through the tests with field-scaled Solid-Liquid separation equipment. The appropriate coagulant for the conditioning of dewatering property was E-851, which is a cationic polyelectrolyte made of polyacrylamide, and the optimum dosage was 0.24~0.6% of unit solids weight. Mesh Screen, Drum Screen, Cyclone Drum Filter, Screw Press, High-speed Screw Decanter, Low-speed Screw Decanter, and Dissolved Air Flotation Process had been investigated in this study. According to the results, the Screw Press was the best dewatering equipment for the small & medium size for feedlot and low-speed Screw Decanter was the best for the large size feedlot & public owned treatment facilities for the primary Solid-Liquid separation, and the most suitable secondary treatment process was DAF. On the other hand, reductions for the requirement of bulking agent and organic loading by Solid-Liquid separation process were 94.8% and 84.7%, respectively Therefore, the Solid-Liquid separation process must be required for the successful treatment of swine wastewater from slurry feedlot.

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