• Title/Summary/Keyword: optimal pre-treatment

Search Result 141, Processing Time 0.025 seconds

Evaluation of stress-induced analgesia in acupuncture analgesic effect - An Approach on diameters of acupuncture needles and acupuncture point needlings - (침진통 효과에서 스트레스에 의한 진통 효과 개입 여부 평가 - 침굵기, 침자극 부위를 중심으로 -)

  • Jeong, Byeong-Ju;Choe, Il-Hwan;Shin, Hee-Sup;Lim, Sabina
    • Korean Journal of Acupuncture
    • /
    • v.25 no.3
    • /
    • pp.65-80
    • /
    • 2008
  • Objective : In recent years, many investigators have questioned whether the analgesic effect of acupuncture is simply related to the stress-induced analgesia (SIA). However, there has been lack of studies on this issue. In this study, the stress levels induced by manual acupunctures are compared with the stress in animal experiment models. The experiments have been carried out with Sprague Dawley (SD) rats. Method : For stress level evaluation, Hot plate test has been used. Maximum Possible Effect (MPE) has been measured by checking the pre-test time and post-test time. Cortisol and corticosterone concentrations in serum were measured by enzyme-linked immunosorbent assay (ELISA). Results : In the hot plate test, MPE values of post-test time were significantly decreased after 10 minutes than after 5 minutes. Therefore, optimal time interval was chosen as 10 minutes. There was significant difference of MPE values between Suspension group and all other treatment groups. However, there were no significant differences of MPE values between Sham group and all other treatment groups. However, MPE values showed tendency to decrease when acupuncture needle diameter increased. MPE values of ST040, ST040(lido), NAP040(lido) groups were markedly decreased than that of Suspension group, while that of NAP040 group was substantially increased than that of Sham group increased in acupoint and nonacupoint models. Serum cortisol concentrations of treatment groups were not significantly different from that of Suspension and Sham groups. Serum corticosterone concentration of 0.25 mm group was substantially increased than that of compared with Sham group. Serum cortisol and corticosterone concentrations of treatment groups were not significantly different from those of Suspension and Sham groups in acupoint and nonacupoint models. Conclusion : From hot plate test and serum stress hormones concentrations, it is found that manual acupuncture treatment induces negligible stress or SIA on ST36. And the stress induced by manual acupuncture is more closely related to acupuncture point needlings than diameters of acupuncture needles.

  • PDF

Long-term clinical outcome of acute myocardial infarction according to the early revascularization method: a comparison of primary percutaneous coronary interventions and fibrinolysis followed by routine invasive treatment

  • Min, Hyang Ki;Park, Ji Young;Choi, Jae Woong;Ryu, Sung Kee;Kim, Seunghwan;Song, Chang Sup;Kim, Dong Shin;Song, Chi Woo;Kim, Se Jong;Kim, Young Bin
    • Journal of Yeungnam Medical Science
    • /
    • v.34 no.2
    • /
    • pp.191-199
    • /
    • 2017
  • Background: This study was conducted to provide a comparison between the clinical outcomes of primary percutaneous coronary intervention (PCI) and that of fibrinolysis followed by routine invasive treatment in ST elevation myocardial infarction (STEMI). Methods: A total of 184 consecutive STEMI patients who underwent primary PCI or fibrinolysis followed by a routine invasive therapy were enrolled from 2004 to 2011, and their major adverse cardiovascular events (MACEs) were compared. Results: Among the 184 patients, 146 patients received primary PCI and 38 patients received fibrinolysis. The baseline clinical characteristics were similar between both groups, except for triglyceride level ($68.1{\pm}66.62$ vs. $141.6{\pm}154.3mg/dL$, p=0.007) and high density lipoprotein level ($44.6{\pm}10.3$ vs. $39.5{\pm}8.1mg/dL$, p=0.005). The initial creatine kinase-MB level was higher in the primary PCI group ($71.5{\pm}114.2$ vs. $35.9{\pm}59.9ng/mL$, p=0.010). The proportion of pre-thrombolysis in MI 0 to 2 flow lesions (92.9% vs. 73.0%, p<0.001) was higher and glycoprotein IIb/IIIa inhibitors were administered more frequently in the primary PCI group. There was no difference in the 12-month clinical outcomes, including all-cause mortality (9.9% vs. 8.8%, p=0.896), cardiac death (7.8% vs. 5.9%, p=0.845), non-fatal MI (1.4% vs. 2.9%, p=0.539), target lesion revascularization (5.7% vs. 2.9%, p=0.517), and stroke (0% vs. 0%). The MACEs free survival rate was similar for both groups (odds ratio, 0.792; 95% confidence interval, 0.317-1.980; p=0.618). The clinical outcome of thrombolysis was not inferior, even when compared with primary PCI performed within 90 minutes. Conclusion: Early fibrinolysis with optimal antiplatelet and antithrombotic therapy followed by appropriate invasive procedure would be a comparable alternative to treatment of MI, especially in cases of shorter-symptom-to-door time.

A Study on the Development and Application of Korean Medical Critical Pathway of Lumbar Disc Herniation in Four Different Medical Associations (요추 추간판 탈출증의 4종 한의표준임상경로(CP) 개발 및 시범적용 연구)

  • Kim, Jung-Hyun;Chae, Sang Yeup;Ko, Min-Jung;Jo, Min-Gi;Jang, Jun-Yeong;Kim, Jun Yeon;Kim, Ha-Na;Park, Kyeong Ju;Hwang, Ji-Min;Goo, Bonhyuk;Park, Yeon-Cheol;Baek, Yong-Hyeon;Nam, Sang-Soo;Seo, Byung-Kwan
    • The Journal of Korean Medicine
    • /
    • v.42 no.3
    • /
    • pp.1-8
    • /
    • 2021
  • Objectives: A critical pathway defines the optimal care process, sequencing and timing of intervention by multi-disciplinary health care teams for a particular diagnosis and procedure. It plays an important role as a cost-effective health care delivery system and a tool for quality control of medical and dental services by means of standardizing medical practices. The aim of this study is to investigate the satisfaction of patients and medical staff after implementation of a critical pathway for Korean medical treatment of lumbar disc herniation in integrative medical. Methods and Results: The pre-critical pathway group included 3 patients who underwent the implementation procedure from October 2020. All three patients have successfully been applied critical pathways during inpatient and outpatient treatment. Additionally, medical staff members were satisfied with the usefulness of the critical pathway. Conclusions: The implementation of critical pathway for the Korean medical treatment with lumbar disc herniation in integrative medical hospital can appraise possible applicability in actual clinical field.

Dissolution Conditions of Solid Radioactive Wastes Generated from NPP for the Analysis of Radionuclides Using a Closed-vessel Microwave Acid Digestion System (원전 발생 고체 방사성폐기물 내 핵종 분석을 위한 극초단파 산분해 장치를 이용한 용액화 조건)

  • 표형열;이정진;전종선;이창헌;지광용
    • Proceedings of the Korean Radioactive Waste Society Conference
    • /
    • 2004.06a
    • /
    • pp.158-166
    • /
    • 2004
  • The optimal conditions are obtained for the decomposition of solid radioactive wastes, including ion exchange resin, zeolite, active charcoal, and sludge from nuclear power plant. In the process of decomposing the radioactive wastes were used the microwave acid digestion method with mixed acid. The solution after acid digestion by the following method was colorless and transparent. Each solution was analyzed with ICP-AES and AAS and the recovery yield for 5 different elements added the simulated radioactive wastes were over 94%. As an effective pre-treatment, the proposed microwave acid digestion conditions concerning the chemical trait of each radioactive waste are expected to be generally applied to above-mentioned radioactive wastes from nuclear power plant hereafter.

  • PDF

Effect of re-based Coagulants on Cell Separation Efficiency from the Culture Broth of Alcaligenes eutrophus. (Alcaligenes eutrophus의 배양액으로부터 균체 분리 효율에 미치는 철(Fe)계 응집제의 효과)

  • 류희욱;조경숙;곽종운;장용근
    • Microbiology and Biotechnology Letters
    • /
    • v.26 no.3
    • /
    • pp.257-263
    • /
    • 1998
  • Alcaligenes eutrophus was successfully recovered from high cell density broth by pre-treatment with Fe-based coagulants. An inorganic coagulant, Fe$_2$(SO$_4$)$_3$, and a polymerized coagulant, Ferix-3, were used. Good coagulation was observed in broad pH range of 3 to 13, the floe size was increased with increasing pH of culture broth. The optimum pH of fermentation broth for cell recovery was 10 to 13. The optimum coagulant dosages to recover cells with 95% cell recovery were increased with increasing cell concentration. Optimal coagulant dosage was lower when the polymerized coagulant was used rather than the inorganic coagulant. The coexistence of NH$_4$$\^$+/ was increased coagulant requirement, and the coagulant requirement was 0.066g Fe$_3$$\^$+//g NH$_4$$\^$+/.

  • PDF

Natural Dyeing of Fabrics with Corydalis Tuber Extract - Dyeability and Functionality of Wool Fabrics - (현호색 추출액을 이용한 직물의 천연염색 - 모직물의 염색성과 기능성 -)

  • Kim, Kwan-Young;Lee, Mun-Soo
    • Fashion & Textile Research Journal
    • /
    • v.19 no.5
    • /
    • pp.620-625
    • /
    • 2017
  • In this study, the dyeing conditions(temperature, time, concentration) are changed from various conditions on wool fabrics by using corydalis tuber extract in order to develop new natural dyes. The purpose of this study is to improve the dyeability, color fastness, and functionality and to derive optimal dyeing conditions by comparing and analyzing the changes of K/S values and surface color by dyeing pH changes, mordant method, and mordant type. As a result of the experiment, the optimum dyeing condition of the wool fabrics is shown dyeing temperature:$80^{\circ}C$, dyeing time:90min, dyeing concentration:100%. The dyeability by pH variants of corydalis tuber extract indicates that K/S values is higher alkaline than acidic. The mordant method of corydalis tuber extract showed pre-mordant has high K/S values. In terms of color fastness, marked improvement has not been shown despite of mordant treatment on wool fabrics. In particular, color change of color fastness to washing, color fastness to light indicates the low fastness. In addition, the functionality such as antibacterial activities and deodorization can be given at dyeing with corydalis tuber extract thus it is expected to be applied to underwear or apparel products for the elderly and infirm and children with weak skin that required high functionality.

Determination of major and minor elements in low and medium level radioactive wastes using closed-vessel microwave acid digestion (밀폐형 극초단파 산분해법을 이용한 중${\cdot}$저준위 방사성폐기물의 성분 원소 분석)

  • Lee Jeong-Jin;Pyo Hyung-Yeal;Jeon Jong-Seon;Lee Chang-Heon;Jee Kwang-Yong;Ji Pyung-Kook
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
    • /
    • v.2 no.4
    • /
    • pp.231-238
    • /
    • 2004
  • The conditions are obtained for the decomposition of solid radioactive wastes, including ion exchange resin, zeolite, charcoal, and sludge from nuclear power plant. In the process of decomposing the radioactive wastes was used the microwave acid digestion method with mixed acid. The solution after acid digestion by the following method was colorless and transparent. Each solution was analyzed with ICP-AES and AAS and the recovery yield for 5 different elements added into the simulated radioactive wastes were over $94{\%}$. The elemental analysis of destructive low and medium level radioactive wastes by the proposed microwave acid digestion conditions concerning the chemical characteristics of each radioactive waste are expected to be useful basic data for development of optimal glass formulation.

  • PDF

Monitoring of Roasting Conditions for the Functional Properties of Lateral Root of Red Ginseng (홍삼의 기능적 특성에 대한 볶음 조건 모니터링)

  • Jeon, Eun-Ju;Kim, Kyo-Yeon;Lee, Jeog-Eun;Waje, Catherine;Kwon, Joong-Ho
    • Food Science and Preservation
    • /
    • v.15 no.3
    • /
    • pp.396-404
    • /
    • 2008
  • This study investigated the functional properties of lateral roots of red ginseng following roasting treatment The ten different conditions, based on the central composite design for roasting parameters, were pre-established according to roasting temperature($140{\sim}240^{\circ}C$) and time($5{\sim}25\;min$). The functional characteristics were monitored using response surface methodology, whereby polynomial equations and correlation coefficients were investigated between roasting conditions. The functional properties of the samples were affected more by roasting time than temperature. The optimal roasting condition ranges for maximizing the functional qualities of lateral roots of red ginseng were predicted to be a roasting temperature of $194.5-210.9^{\circ}C$, and a roasting time of 13.8-20.0 min.

Comparative Study of Mechanical and VOC Properties According to Manufacturing Conditions of Glass Fiber/Bamboo Fiber/PP Composites (유리섬유/대나무섬유/PP 복합재의 제조 조건에 따른 기계적 및 VOC 특성 비교 연구)

  • Lee, Su-kyoung;Park, Tae-sung;An, Seung-kook
    • Textile Coloration and Finishing
    • /
    • v.33 no.3
    • /
    • pp.153-160
    • /
    • 2021
  • In this study, composite materials were prepared by varying the content of glass fiber and bamboo fiber in PP/glass fiber/bamboo fiber. Experiments were conducted to confirm the mechanical properties(tensile, impact and burst strength) and volatile organic compound content of the bamboo fiber composite prepared under these conditions. An improvement in the main properties was observed at a fiber content of 30wt%. When the fiber fraction was increased above 30wt%, the mechanical properties tended to decrease due to the agglomeration of fibers at higher load fractions. In addition, the content of volatile organic compounds increased as the content of bamboo fibers increased, which is thought to be due to the volatile organic compounds generated during the manufacturing process of the composite material being present in the composite material without escaping from the pores of the bamboo fibers and volatilizing at a certain temperature. As a result of confirming the physical properties of the composite, it is considered that the optimal mixing condition is 30wt% of bamboo fiber for the composite produced by varying the amount of bamboo fiber composite. In the future, it is thought that follow-up experiments to confirm and improve the pre-treatment conditions for reducing the content of volatile organic compounds in the manufactured composite material are possible.

Pre-Hospital and In-Hospital Management of an Abdominal Impalement Injury Caused by a Tree Branch

  • Ahn, So Ra;Lee, Joo Hyun;Kim, Keun Young;Park, Chan Yong
    • Journal of Trauma and Injury
    • /
    • v.34 no.4
    • /
    • pp.288-293
    • /
    • 2021
  • In South Korea, most patients who visit trauma centers with abdominal injuries have blunt trauma, and penetrating injuries are relatively rare. In extremely rare cases, some patients are admitted with a long object penetrating their abdomen, and these injuries are referred to as abdominal impalement injuries. Most cases of impalement injuries lead to fatal bleeding, and patients often die at the scene of the accident. However, patients who survive until reaching the hospital can have a good prognosis with optimal treatment. A 68-year-old female patient was admitted to the trauma center with a 4-cm-thick tree branch impaling her abdomen. The patient was transported by a medical helicopter and had stable vital signs at admission. The branch sticking out of the abdomen was quite long; thus, we carefully cut the branch with an electric saw to perform computed tomography (CT). CT revealed no signs of major blood vessel injury, but intestinal perforation was observed. During laparotomy, the tree branch was removed after confirming that there were no vascular injuries, and enterostomy was performed because of extensive intestinal injury. After treating other injuries, the patient was discharged without any complications except colostomy. Abdominal impalement injuries are treated using various approaches depending on the injury mechanism and injured region. However, the most important consideration is that the impaled object should not be removed during transportation and resuscitation. Instead, it should only be removed after checking for injuries to blood vessels during laparotomy in an environment where injury control is possible.