• 정보과학회 논문지
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• 제44권10호
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• pp.1026-1033
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• 2017

본 논문은 계층적 디리슐레 과정(HDP)과 은닉 마르코프 모형(HMM)이 결합된 베이스 통계학적 방법과 HMM의 상태 지속 정보를 이용한 건강 상태 예측 방법을 제안한다. HDP-HMM은 베이스 방법의 HMM 확장 모형으로서 건강의 동적 특성을 고려하여 불확실하고 가늠하기조차도 어려운 건강 상태의 수를 추정할 수 있게 해준다. 모의 데이터와 실제 건건 검진 데이터를 이용한 시험을 통하여 흥미 있는 행동 특성을 볼 수 있었으며 최대 5년까지로 제한한 미래 예측도 충분한 가능함을 확인하였다. 미래는 불확실하며 예측 문제는 본질적으로 어렵다. 그러나 본 연구의 실험 결과로 동적인 문맥 하에서 다중 후보 가설을 제시함으로서 실용 가능한 건강상태의 장기 예측이 가능하다는 것을 읽을 수 있었다.

• International Journal of Industrial Entomology and Biomaterials
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• 제25권2호
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• pp.159-162
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• 2012

The Chinese windmill butterfly, Atrophaneura alcinous, is an important butterfly for exhibition in butterfly garden. The objective of this study was to determine the effect of temperature on A. alcinous in the laboratory. Development of A. alcinous reared on leaves of Aristolochia contorta was investigated at five constant the laboratory condition (20, 22.5, 25, 27.5 and $30^{\circ}C$) and at relative humidity of 60% with a photoperiod of 14:10 (L:D). Temperatures have been suggested as an important determinant of developmental rate, lifespan and mortality in invertebrates. As the temperature increased, the length of the developmental period gradually decreased. The developmental time (pupation) from egg hatching to pupation was respectively 25.8, 23.6, 19.6, 15.5, and 12.9 days at the temperatures of 20, 22.5, 25, 27.5 and $30^{\circ}C$. And pupation was respectively 40.0, 30.0, 63.4, 50.0, 23.3% at the temperatures of 20, 22.5, 25, 27.5 and $30^{\circ}C$. The developmental threshold temperature estimated for egg-to-pupae was 10.8, with a thermal constant of 230.4 degree-days. Therefore, the optimal developmental temperature for A. alninous was determined to be $25^{\circ}C$. To compare the effects of the total duration of chilling on the termination of diapause, larvae were subjected to a temperature of $8^{\circ}C$ from 60 to 120 days. The rate of termination of diapause was significantly higher at 60 days compared to other incubation period.

• 한국가축번식학회지
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• 제18권2호
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• pp.113-119
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• 1994

To improve nuclear transplantation(NT) efficiency and to produce a large scale genetically identical cloned calves, examined the in vitro development capacity after co-culture of bovine oviductal epithelial cells (BOEC) and granulosa cells in TCM-199 supplemented with 10% fetal calf serum (FCS) with early bovine embryos derived from in vitro matured fertilized(IVM-IVF) oocyte. In addition, the age dependence of IVM oocyte on electro-stimulation and the effective electric voltage on in ivtro development of bovine NT embryos were examined. The results obtained were summerized as follows; 1. The cleavage rates of IVM-IVF bovine embryos in co-culture with bovine oviductal epithelial cells and granulosa cells were not significantly different(P<0.05), but the developmental rate into morula and blastocyst stage were different showing 38.3 and 20.2%, respectively. 2. The activation (82.5%) and development in vitro(8.6%) into later embryo stages of the aging oocytes of 32 hours post-maturation (hpm) were significantly higher than those of 24 hpm at direct current (DC) voltage of 1.5kV/cm, 60$\mu$sec pulse duration and 1 pulse time. 3. The fusion rates of NT eggs of 32 hpm following to different DC voltages from range 0.75 to 1.5kV/cm were not differ, but the developmental rate into morula and blastocyst stages at DC voltages of 0.75 and 1.0kV/cm were higher(11.4 and 12.6%, respectively) than those of 1.5kV/cm(0%). From these results, it can be suggested the optimal culture system for in vitro culture of IVM-IVF bovine embryos is a co-culture system with BOEC in TCM-199 supplemented 10% FCS. The effective time and the DC voltage for activation, electrofusion and in vitro development of NT embryos derived from IVM-IVF bovine embryo are 32hpm and 0.75~1.0kV/cm. But to improve NT efficiency, the advanced research (cell cycle synchronization, micromanipulation, culture system, etc.) is needed.

• Journal of Yeungnam Medical Science
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• 제33권1호
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• pp.40-43
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• 2016

Retroperitoneal fibrosis (RF) is a disorder characterized by the presence of a retroperitoneal mass and concurrent systemic inflammation. Some cases of RF are recognized as belonging to the spectrum of immunoglobulin G4-related disease (IgG4-RD). Glucocorticoids are highly effective for treatment of retroperitoneal fibrosis, although the optimal dose and duration of therapy have not been established. An initial dose of prednisone (40-60 mg) daily is usually administered with a tapering scheme. We report on a 55-year-old man diagnosed with IgG4-related RF and successfully treated with a 3-day course of daily 250 mg (4 mg/kg) intravenous methylprednisolone, which resulted in the prompt resolution of urinary obstruction and systemic symptoms.

• Journal of Biosystems Engineering
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• 제33권5호
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• pp.317-325
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• 2008

The electrocardiogram (ECG) measurement system consists of I/O interface to input the ECG signals from two electrodes, FPGA (Field programmable gate arrays) module to process the signal conditioning, and real time module to control the system. The algorithms based on wavelet transform were developed to remove the noise of the ECG signals and to determine the QRS-waves. Triangular wave tests were conducted to determine the optimal factors of the wavelet filter by analyzing the SNRs (signal to noise ratios) and RMSEs (root mean square errors). The hybrid rule, soft method, and symlets of order 5 were selected as thresholding rule, thresholding method, and mother wavelet, respectively. The developed wavelet filter showed good performance to remove the noise of the triangular waves with 10.98 dB of SNR and 0.140 mV of RMSE. The ECG signals from a total of 6 subjects were measured at different measuring postures such as lying, sitting, and standing. The durations of QRS-waves, the amplitudes of R-waves, the intervals of RR-waves were analyzed by using the finite impulse response (FIR) filter and the developed wavelet filter. The wavelet filter showed good performance to determine the features of QRS-waves, but the FIR filter had some problems to detect the peaks of Q and S waves. The measuring postures affected accuracy and precision of the ECG signals. The noises of the ECG signals were increased due to the movement of the subject during measurement. The results showed that the wavelet filter was a useful tool to remove the noise of the ECG signals and to determine the features of the QRS-waves.

• 생물환경조절학회지
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• 제6권4호
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• pp.310-316
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• 1997

본 연구는 온실멜론의 양액재배에서 영양진단에 기초한 배양액관리를 하기 위해 유효한 수단으로 이용할 수 있고 신속하고 간편하며 정확한 즙액분석 방법(질산태질소의 정량방법, 인산정량방법, 즙액추출법, 추출비율, 마쇄시간 및 샘플채취 부위 등)들에 관한 비교검토를 하였다. 'Earl's Favorite 춘계를 1993년 1월 11일에 파종하여 본엽 3∼4매의 묘를 정식하여 비순환 방식으로 재배했다. 즙액분석법은 결핍이나 과잉증상이 외관적으로 나타나기 전에 신속하고 간이한 즙액분석법에 의해 물체의 영양상태를 진단하여 대응이 가능하다고 판단되었다. 즙액분석시 질산태질소의 분석에는 자외부 흡광도법, 인산분석에는 바나드몰리브덴산법이 추천되었고, 추출비율은 1：4로, 엽병의 마쇄시간은 60초, 그리고 채취부위는 일정부위로 하는 것이 바람직하다고 판단되었다. 그러나 샘플채취시간에 대해서는 채취시간에 따른 차이가 크기 때문에 앞으로 보다 상세한 검토가 요청되었다.

• Journal of Microbiology and Biotechnology
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• 제25권3호
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• pp.358-365
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• 2015

ε-Poly-L-lysine (ε-PL) is a homopolymer of L-lysine molecules connected between the epsilon amino and alpha carboxyl groups. This polymer is currently used as a natural preservative in food. Insufficient biomass is a major problem in ε-PL fermentation. Here, to improve cell growth and ε-PL productivity, various nitrogen-rich nutrients were supplemented into flask cultures after 16 h cultivation, marking the onset of ε-PL biosynthesis. Yeast extract, soybean powder, corn powder, and beef extract significantly improved cell growth. In terms of ε-PL productivity, yeast extract at 0.5% (w/v) gave the maximum yield (2.24 g/l), 115.4% higher than the control (1.04 g/l), followed by soybean powder (1.86 g/l) at 1% (w/v) and corn powder (1.72 g/l) at 1% (w/v). However, supplementation with beef extract inhibited ε-PL production. The optimal time for supplementation for all nutrients examined was at 16 h cultivation. The kinetics of yeast-extract-supplemented cultures showed enhanced cell growth and production duration. Thus, the most commonly used two-stage pH control fed-batch fermentation method was modified by omitting the pH 5.0-controlled period, and coupling the procedure with nutrient feeding in the pH 3.9-controlled phase. Using this process, by continuously feeding 0.5 g/h of yeast extract, soybean powder, or corn powder into cultures in a 30 L fermenter, the final ε-PL titer reached 28.2 g/l, 23.7 g/l, and 21.4 g/l, respectively, 91.8%, 61.2%, and 45.6% higher than that of the control (14.7 g/l). This describes a promising option for the mass production of ε-PL.

• 한국방재학회 논문집
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• 제10권3호
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• pp.109-118
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• 2010

본 연구에서는 소규모 저류시설의 유출저감효과를 NRCS 유출곡선지수의 감소율로 정량화하였다. 저류시설로 유입되는 유출용적을 계산하기 위해 수정합리식을 이용하였다. 다양한 강우 특성(강우 빈도, 지속시간)과 저류시설의 규모에 따라 설치 전후의 NRCS 유출곡선지수 감소율을 정량화하였다. 마지막으로 저류시설의 규모에 따른 유출곡선지수의 감소율을 나타내는 도표를 개발하였다. 이 도표는 저류시설의 최적 위치 및 용량 결정을 할 경우 저류시설의 효율을 평가하는데 합리적이고 효율적으로 활용될 수 있을 것으로 기대된다. 본 연구에서 제안된 방법에 의한 결과는 또한 기존 연구와의 비교를 통해 검증하였다.

• 한국운동역학회지
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• 제16권4호
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• pp.175-187
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• 2006

The purpose of this study was to find the relationship between Achilles tendon angle, angular velocity from 2D cinematography utilized to easily analyze the functions of shoes, ankle joint moment, knee joint moment, and hip joint moment from 3D cinematography utilized to predict the injury. Also, this study was to provide the optimal standard to analyze the injury related to the shoes. Subjects in this study were 30 university male students and 18 conditions (2 types of running speed, 3 of midsole hardness, 3 of midsole height) were measured using cinematography and force platform. The results were as following. 1) Hip joint abduction moment was effected by many variables such as running speed, midsole height, maximum achilles tendon angle, ground reaction force. 2) Knee joint rotational moment in running was approximately 1/10 - 1/4 times of the injury critical value and eversion moment was approximately 1/4 - 1/2 times of the injury critical value. 3) Ankle joint pronation moment in running was 1/3 - 1/2 times of the injury critical value. 4) Knee joint rotational moment was found to be irrelevant with maximum achilles tendon angle or angular velocity. 5) Pronation from running was thought to be relevant to rather eversion moment activity than rotational moment activity of knee joint. 6) Plantar flexion abductor of ankle showed significant relationship with the ground reaction force variable. 7) When the loading rate for ground reaction force in passive region increased, extensor tended to be exposed to the injury. Main variables in biomechanical analysis of shoes were impact absorption and pronation. Among these variables, pronation factor was reported to be relevant with knee injury from long duration exercise. Achilles tendon angle factor was utilized frequently to evaluate this. However, as the results of this study showed, the relationship between these variables and injury relating variable of knee moment was so important. Studies without consideration on this finding should be reconsidered and reconfirmed.

• International Journal of Industrial Entomology and Biomaterials
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• 제32권1호
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• pp.41-48
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• 2016

Mealworms, Tenebrio molitor (Coleoptera: Tenebrionidae), are widely used as food sourcefor animal rearing as well as human diet. Conventionally, mealworms raised on wheat bran. In this study, we investigated the effects of brewer's spent grain (BSG) on the growth of mealworm larvae to reduce the rearing cost. We prepared five different diets with various BSG content, 0, 10, 30, 50, and 70% of heated air dried BSG with wheat bran. We compared survivorship, larval weight, developmental duration, pupation rate, and pupal weight of five different groups of T. molitor raised on these five diets. The larval survivorships were almost similar with the control group except a group with 70% of BSG. For the larval weight, groups with 30% and 50% of BSG gained more weight than that with control treatment, 0% of BSG. For the developmental period, the groups with 30% of BSG took less time compared to the control group. In all treatment groups, more than 90% of pupation rate were observed. Especially, the group with 30% of BSG showed highest pupation rate among the five groups. Wheat bran with 30~50% of BSG was the optimal diet for successive insect rearing among the five diet treatments. Based on this study, we concluded that adding BSG to wheat bran helps to improve the quality of T. molitor and to reduce the rearing period.