• Title/Summary/Keyword: operating characteristic

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Analysis of SEER Glassy Cell Carcinoma Data: Underuse of Radiotherapy and Predicators of Cause Specific Survival

  • Cheung, Rex
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.1
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    • pp.353-356
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    • 2016
  • Background: This study used receiver operating characteristic curve to analyze Surveillance, Epidemiology and End Results (SEER) for glassy cell carcinoma data to identify predictive models and potential disparities in outcome. Materials and Methods: This study analyzed socio-economic, staging and treatment factors. For risk modeling, each factor was fitted by a generalized linear model to predict the cause specific survival. Area under the receiver operating characteristic curves (ROCs) were computed. Similar strata were combined to construct the most parsimonious models. A random sampling algorithm was used to estimate modeling errors. Risk of glassy cell carcinoma death was computed for the predictors for comparison. Results: There were 79 patients included in this study. The mean follow up time (S.D.) was 37 (32.8) months. Female patients outnumbered males 4:1. The mean (S.D.) age was 54.4 (19.8) years. SEER stage was the most predictive factor of outcome (ROC area of 0.69). The risks of cause specific death were, respectively, 9.4% for localized, 16.7% for regional, 35% for the un-staged/others category, and 60% for distant disease. After optimization, separation between the regional and unstaged/others category was removed with a higher ROC area of 0.72. Several socio-economic factors had small but measurable effects on outcome. Radiotherapy had not been used in 90% of patients with regional disease. Conclusions: Optimized SEER stage was predictive and useful in treatment selection. Underuse of radiotherapy may have contributed to poor outcome.

Characteristic Analysis of Double Effect Absorption Refrigeration Machine using $H_{2}O/LiBr+HO{(CH_{2})}_{3}OH$ ($H_{2}O/LiBr+HO{(CH_{2})}_{3}OH$를 이용한 2중 효용 흡수식 냉동기 특성해석)

  • 문춘근
    • Journal of Advanced Marine Engineering and Technology
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    • v.22 no.6
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    • pp.792-799
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    • 1998
  • Further improvement of existing $H_{2}O/LiBr$ absorption refrigeration machine is absolutely neces-sary to promote the utilization of gas-cooling system Among various methods to improve the per-formance of the absorption refrigeration machine this research has focused on the use of a new working fluid that has better properties than the existing $H_{2}O/LiBr$ working fluid. In the series of the research, $H_{2}O/LiBr+HO{(CH_{2})}_{3}OH$ system was selected as the most promisable candidate. The absorption refrigeration machine is water-cooled double-effect, $H_{2}O/LiBr+HO{(CH_{2})}_{3}OH$ sys-tem with series flow type. In this study we found out the characteristic of new working solution through the cycle simulation and compared the result with that of LiBr solution to evaluate. Theoptimum designs and operating conditions were determined based on the operating constraints and the coefficient of performance. Results demonstrate that new working fluid subsrantially increases COP by as much as 10% and has a wider working range with 8% higher crystallization limits compared to the conventional $H_{2}O/LiBr$.

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Partial AUC using the sensitivity and specificity lines (민감도와 특이도 직선을 이용한 부분 AUC)

  • Hong, Chong Sun;Jang, Dong Hwan
    • The Korean Journal of Applied Statistics
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    • v.33 no.5
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    • pp.541-553
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    • 2020
  • The receiver operating characteristic (ROC) curve is expressed as both sensitivity and specificity; in addition, some optimal thresholds using the ROC curve are also represented with both sensitivity and specificity. In addition to the sensitivity and specificity, the expected usefulness function is considered as disease prevalence and usefulness. In particular, partial the area under the ROC curve (AUC) on a certain range should be compared when the AUCs of the crossing ROC curves have similar values. In this study, partial AUCs representing high sensitivity and specificity are proposed by using sensitivity and specificity lines, respectively. Assume various distribution functions with ROC curves that are crossing and AUCs that have the same value. We propose a method to improve the discriminant power of the classification models while comparing the partial AUCs obtained using sensitivity and specificity lines.

Zig-zag electrode pattern for improvement of electro-optic characteristic in polymer stabilized blue phase liquid crystal cell (고분자 안정화 블루상 액정셀의 전기광학특성 향상을 위한 지그재그 형태 전극 설계)

  • Kang, Wan-Seok;Mun, Byung-June;Lee, Gi-Dong
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.15 no.1
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    • pp.183-187
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    • 2011
  • The polymer-stabilized blue phase liquid crystal (BPLC) cell has advantages such as sub-millisecond response time, wide viewing angle and no rubbing process for the alignment of liquid crystals. However, high operating voltage and low kerr constant of the polymer-stabilized blue phase liquid crystal deteriorate the electro-optical characteristic of the polymer-stabilized BPLC cell. In this paper, we proposed novel zig-zag electrode in cell layout and confirmed that proposed electrode shape could reduce an over 25 percent of operating voltage for BPLC cell without degradation of tranmittance by using Kerr constant simulation.

Diagnostic accuracy of digital images for detection of artificial chemical proximal caries (화학적 인공 인접면 치아우식증의 디지털 영상 진단능 평가)

  • Park Geum-Mee;Nah Kyung-Soo
    • Imaging Science in Dentistry
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    • v.33 no.2
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    • pp.91-95
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    • 2003
  • Purpose : To compare the diagnostic accuracy of proximal caries detection between Kodak Insight film and the Biomedisys CDX2000HQ digital (CCD) sensor. Materials and Methods: 156 proximal surfaces of extracted teeth, 78 of which had chemical artificial caries, were used in this study. Four observers interpreted the radiographs using a five-point confidence rating scale to record their diagnoses. The results were analyzed by receiver operating characteristic curves, ANOVA and Kappa values. Result: Analysis using receiver operating characteristic curves revealed the areas under each curve which indicated a diagnostic accuracy of 0.951 in Insight and 0.952 in CDX2000HQ digital sensor. ANOVA revealed no significant differences between the two images with respect to caries detection. Kappa values indicated that the mean intra-observer agreement was 0.85 and inter-observer agreement 0.71 in conventional radiography. In digital radiography, the mean intra-observer agreement was 0.84 and inter-observer agreement 0.72. Conclusion: The results suggest that no significant difference exists between the two modalities for artificial caries detection and that CDX2000HQ was as good as Insight film for this purpose.

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Development of Fast-Response CO2 Analyzer and Analysis of Engine-out Emission during Cold Start of SI Engine (고속응답 CO2 분석기의 제작 및 이를 이용한 SI엔진에서의 실시간 배기가스 분석에 관한 연구)

  • Song, Hyun-Soo;Park, Kyoung-Seok;Park, Dong-Sun;Min, Kyoung-Doug
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.33 no.2
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    • pp.133-140
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    • 2009
  • A fast-response $CO_2$ analyzer has been developed for measuring the $CO_2$ concentration during transient condition of a SI engine. The analyzer consists of the non-dispersive infrared absorption method, electrical chopping system and water cooling system. The analyzer has good repeatability, linearity and permissible drift characteristic. Besides, it showed 18ms of a response to measure the $CO_2$ concentration. The fast-response $CO_2$ analyzer was applied to a single cylinder SI engine and the $CO_2$ emission was examined during engine start. Simultaneously, the standard exhaust gas analyzer, which has slow response time, was used for confirming the accuracy of the exhaust gas analysis using the fast-response $CO_2$ analyzer. The developed analyzer showed much faster responsive characteristic than that of a standard analyzer and made cycle by cycle exhaust gas analysis possible. The transient engine operating characteristics will be estimated from the $CO_2$ concentration of engine-out emissions and engine operating variables.

Numerical Bayesian updating of prior distributions for concrete strength properties considering conformity control

  • Caspeele, Robby;Taerwe, Luc
    • Advances in concrete construction
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    • v.1 no.1
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    • pp.85-102
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    • 2013
  • Prior concrete strength distributions can be updated by using direct information from test results as well as by taking into account indirect information due to conformity control. Due to the filtering effect of conformity control, the distribution of the material property in the accepted inspected lots will have lower fraction defectives in comparison to the distribution of the entire production (before or without inspection). A methodology is presented to quantify this influence in a Bayesian framework based on prior knowledge with respect to the hyperparameters of concrete strength distributions. An algorithm is presented in order to update prior distributions through numerical integration, taking into account the operating characteristic of the applied conformity criteria, calculated based on Monte Carlo simulations. Different examples are given to derive suitable hyperparameters for incoming strength distributions of concrete offered for conformity assessment, using updated available prior information, maximum-likelihood estimators or a bootstrap procedure. Furthermore, the updating procedure based on direct as well as indirect information obtained by conformity assessment is illustrated and used to quantify the filtering effect of conformity criteria on concrete strength distributions in case of a specific set of conformity criteria.

Determination of cut-off value by receiver operating characteristic curve of norquetiapine and 9-hydroxyrisperidone concentrations in urine measured by LC-MS/MS

  • Kim, Seon Yeong;Shin, Dong Won;Kim, Jin Young
    • Analytical Science and Technology
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    • v.34 no.2
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    • pp.78-86
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    • 2021
  • The objective of this study was to investigate urinary cut-off concentrations of quetiapine and risperidone for distinction between normal and abnormal/non-takers who were being placed on probation. Liquid chromatography-tandem mass spectrometric (LC-MS/MS) method was employed for determination of antipsychotic drugs in urine from mentally disordered probationers. The optimal cut-off values of antipsychotic drugs were calculated using receiver operating characteristic (ROC) curve analysis. The sensitivity and specificity of the method for the detection of antipsychotic drugs in urine were subsequently evaluated. The area under the ROC curve (AUC) was 0.927 for norquetiapine and 0.791 for 9-hydroxyrisperidone, respectively. These antipsychotic drugs are classified readily in the ROC curve analysis. The cut-off values for distinguishing regular and irregular/non-takers were 39.1 ng/mL for norquetiapine and 67.9 ng/mL for 9-hydroxyrisperidone, respectively. The results of this study suggest the cut-off values of quetiapine and risperidone were highly useful to distinguish regular takers from irregular/non-takers.

A comparison of the performance characteristics of large 2 MW and 3 MW wind turbines on existing onshore wind farms

  • Bilgili, Mehmet;Ekinci, Firat;Demirdelen, Tugce
    • Wind and Structures
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    • v.32 no.2
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    • pp.81-87
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    • 2021
  • The aim of the current study is to compare the performance of large 2 MW and 3 MW wind turbines operating on existing onshore wind farms using Blade Element Momentum (BEM) theory and Angular Momentum (AM) theory and illustrate the performance characteristic curves of the turbines as a function of wind speed (U∞). To achieve this, the measurement data obtained from two different Wind Energy Power Plants (WEPPs) located in the Hatay region of Turkey was used. Two different horizontal-axis wind turbines with capacities of 2 MW and 3 MW were selected for evaluation and comparison. The hub-height wind speed (UD), turbine power output (P), atmospheric air temperature (Tatm) and turbine rotational speed (Ω) data were used in the evaluation of the turbine performance characteristics. Curves of turbine power output (P), axial flow induction factor (a), turbine rotational speed (Ω), turbine power coefficient (CP), blade tip speed ratio (λ), thrust force coefficient (CT) and thrust force (T) as a function of U∞ were obtained for the 2 MW and 3 MW wind turbines and these characteristic curves were compared. Results revealed that, for the same wind speed conditions, the higher-capacity wind turbine (3 MW) was operating at higher turbine power coefficient rates, while rotating at lower rotational speed ratios than the lower-capacity wind turbine (2 MW).

Broadband U-Shaped RFID Tag Antenna with Near-Isotropic Characteristic (광대역에서 일정한 준 등방성 특성을 가지는 U-형태의 RFID 태그 안테나)

  • Lee, Sang-Woon;Jung, Hak-Joo;Choo, Ho-Sung;Park, Ik-Mo
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.20 no.5
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    • pp.480-492
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    • 2009
  • In this paper, we proposed a broadband U-shaped RFID tag antenna with near-isotropic characteristic at UHF band. The proposed tag antenna is composed of the U-shaped half wavelength dipole and a rectangular shaped feed. The rectangular shaped feed that is located inside U-shaped dipole is connected for conjugate impedance matching with the commercial tag chip. A better constant gain deviation characteristic in the operating frequency band is achieved by inserting a rectangular slit in the lower center of the U-shaped antenna body. On the condition of VSWR<2, the tag antenna had the measured bandwidth of 10.36%, from 860.5 to 954.5 MHz, and 9.84%, from 864.5 to 954 MHz, for antenna without slit and with slit, respectively. On the condition of VSWR<5.8, the tag antennas had the measured bandwidth of 15.78%, from 835.5 to 979.5 MHz, and 15.89%, from 837 to 981.5 MHz, for antenna without slit and with slit, respectively. The difference between the maximum and minimum gain deviations of tag antenna without slit in the operating frequency band is 0.53 dB since the maximum and minimum gain deviations are 3.86 dB and 3.33 dB, respectively. Whereas the difference between the maximum and minimum gain deviations of tag antenna with slit in the operating frequency is 0.06 dB since the maximum and minimum gain deviations are 3.60 dB and 3.54 dB, respectively.