• The Korean Journal of Physiology and Pharmacology
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• 제2권5호
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• pp.581-589
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• 1998

A regulating mechanism of the ATP-sensitive potassium channels $(K_{ATP}\;channels)$ is yet to fully explained. This study was carried out to investigate the effects of intracellular application of monocarboxylates (acetate, formate, lactate, and pyruvate) on $K_{ATP}$ channels in isolated rabbit ventricular myocytes. Single channel currents of $K_{ATP}$ channels were recorded using the excised inside-out or permeabilized attached (open-cell) patch-clamp technique at room temperature. Intracellular application of acetate, formate and pyruvate led to an inhibition of channel activity, whereas intracellular application of lactate increased channel activity. These effects were reversible upon washout. Analysis of single channel kinetics showed that monocarboxylates did not affect open-time constant and close-time constant. These results suggest that monocarboxylates participate in modulating $K_{ATP}$ channels activity in cardiac cells and that modulation of $K_{ATP}$ channels activity may resolve the discrepancy between the low $K_i$ in excised membrane patches and high levels of intracellular ATP concentration during myocardial ischemia or hypoxia.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제36권1호
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• pp.30-36
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• 2014

There are many treatment options in management of mandibular condylar neck fractures. Closed reduction is the most conservative treatment; however, achievement of anatomic reduction is difficult, and there are some risks of mandibular functional impairment. Open anatomic reduction and internal fixation have some advantages; therefore, many oral and maxillofacial surgeons have attempted to achieve anatomic reduction through the open approach and extracorporeal reduction and fixation. However, when using this method, there is some risk of resorption of the fractured mandibular condylar head. Therefore, we designed a modified extracorporeal reduction technique, without detaching the lateral pterygoid muscle in order to maintain the blood supply to the fractured mandibular condylar head. We believe that this minor modification may minimize the risk of resorption of the fractured mandibular condylar head. In this article, we introduce this technique in detail, and report on two cases.

• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제6권12호
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• pp.581-586
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• 2017

본 연구는 게임을 비롯한 많은 콘텐츠에서 활용하기 위한 GPU기반 사실적 물 애니메이션 기법을 제안한다. 물 표면은 반사 및 굴절과 같은 물리적 현상이 일어나며, 시점에 따른 반사와 굴절의 정도가 자동적으로 조절되어야 한다. 본 논문에서는 GPU 프레임 버퍼를 이용한 렌더투텍스처 방법(RenderToTexture)을 이용하여 반사 및 굴절결과를 텍스처로 저장하며, 이 저장된 데이터에 대한 텍스처 좌표 값을 변형함으로서, 자연스러운 물결의 모습을 표현한다. 또한 표면에 나타나는 굴절 및 반사의 정도가 프레넬(Fresnel) 공식을 통해 시점과 물 표면과의 각도에 따라 자동적으로 계산되도록 한다. 제안된 알고리즘은 윈도우 기반위에서 OpenGL API와 GLSL쉐이더 언어를 통해 구현되었다. 구현 결과, 물결의 자연스러운 움직임이 확인 되었으며, 30 프레임 이상의 속도로 렌더링 되었음이 확인 되었다.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2007년도 Proceedings of ISRS 2007
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• pp.442-444
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• 2007

How to observe the atmosphere is a subject of atmospheric research. The meteorological satellites and the ground states are used to do observation. However, both ways do not satisfy the requirement of scientists, especially the profiles of atmosphere on the ocean and the data for global atmosphere. Radio occultation (RO) technique, which has been used in planet science, is a method to solve the problem. In RO technique, the low Earth orbit (LEO) satellite receives the two frequency signal of Global Positioning System (GPS) satellite. The excess phase of the signal is calculated to retrieve the profiles of atmosphere parameters. In moist troposphere, the fluctuations appear in the phase of the signal and open loop (OL) is used to resolve it. The quality of the GPS signal generally deteriorates as the altitude decreases. In the procedure, the SNR of the GPS signal is used as the criterion. However, the SNR decreases with fluctuation which makes it difficult to locate the data of poor quality. In this paper, the phase of the signal will be used as part of the criterion.

• 대한조선학회논문집
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• 제51권2호
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• pp.162-170
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• 2014

A CFD(Computational Fluid Dynamics) analysis is presented to predict hydrodynamic characteristics of a marine propeller. A commercial RANS(Reynolds Averaged Navier-Stokes equation) solver, namely FLUENT, is utilized in conjunction with fully unstructured meshes around rotating propeller. Mesh generation process is greatly accelerated by using fully unstructured meshes composed of both isotropic and anisotropic tetrahedral elements. The anisotropic tetrahedral elements were used in the flow domain near the blade and shaft, where the viscous effect is important, having complex shape yet resolving the thin boundary layers. For other regions, isotropic tetrahedral elements are utilized. Two different approaches simulating rotational effect of the propeller are employed, namely Moving reference frame technique for steady simulation, and Sliding mesh technique for unsteady simulation. Both approaches are applied to the propeller open water (POW) test simulation. The current results, which are thrust and torque coefficients, are compared with available experimental data.

• Journal of Power Electronics
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• 제11권6호
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• pp.801-810
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• 2011

An open circuit fault diagnostic method in IGBTs for the ac to dc converters used in microgrid applications is developed in this paper. An ac to dc converter is a key technology for microgrids in order to interface both distributed generation (DG) and renewable energy resources (RES). Also, highly reliable ac to dc converters are necessary to keep converters in continuous operation as long as possible during power switch fault conditions. Therefore, the proposed fault diagnostic method is developed to reduce the fault detection time and to avoid any other fault alarms because continuous operation is desired. The proposed diagnostic method is a combination of the absolute normalized dc current technique and the false alarm suppression algorithm to overcome the long fault detection time and fault alarm problems. The simulation and experimental results show that the developed fault diagnostic method can perform fault detection within about one cycle. The results illustrate that the reliability of an ac to dc converter interfaced with a microgrid can be improved by using the proposed fault diagnostic method.

• 대한전기학회논문지:시스템및제어부문D
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• 제55권6호
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• pp.286-295
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• 2006

This paper presents a design of a real-time software GPS receiver which runs on a PC. The software GPS receiver has advantages over conventional hardware based receivers in terms of flexibility and efficiency in application oriented system design and modification. In odor to reduce the processing time of the software operations in the receiver, a shared memory structure is used with a dynamic data control, and the byte-type IF data is processed through an Open Multi-Processing technique in the mixer and integrator which requires the most computational load. A high speed data acquisition device is used to capture the incoming high-rate IF signals. The FFT-IFFT correlation technique is used for initial acquisition and FLL assisted PLL is used for carrier tracking. All software modules are operated in sequence and are synchronized with pre-defined time scheduling. The performance of the designed software GPS receiver is evaluated by running it in real-time using the real GPS signals.

• 대한두개안면성형외과학회지
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• 제23권5호
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• pp.211-219
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• 2022

Background: Correction of secondary cleft nose deformity is one of the most important portions in the management of cleft lip patients. Various techniques have been introduced to achieve adequate shape, balance, and symmetry of anatomical landmarks. None of these methods can claim to universally solve all aspects of the problems encountered in secondary cleft deformity surgery. Some authors overlook the aspect of functional rehabilitation with regard to nasal respiratory pathway problems, which is present in over 90% of the patients. This study aimed to evaluate the aesthetic and functional improvements of the authors' non-destructive technique. Methods: With over 15 years of experience, open rhinoplasty was performed, which included total remodeling of the deformed lower lateral cartilage using several suture fixation techniques without any graft or implantation with septo-turbinoplasty. A total of 150 questionnaires were sent by e-mail, but 55 completed questionnaires were returned. Surgical outcomes were evaluated using questionnaire responses, and outcomes were divided into five categories each for esthetic and functional analyses. Results: The satisfaction rate ranged from 75 % to 98%, which means "more or less," "very much," and "absolutely yes" in the esthetic and functional viewpoints. Conclusion: The results of this study strongly recommend performing the suture fixation technique and functional rehabilitation simultaneously for cleft lip/nose correction.

• 한국터널지하공간학회 논문집
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• 제19권3호
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• pp.489-501
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• 2017

도심지 개착식 굴착공사 중 발생하는 붕괴사고는 공사장 내에서의 인명 및 물질적 피해를 불러일으킬 뿐만 아니라, 공사장 주변의 지반침하로 인한 도로함몰 및 시설물 피해를 유발한다. 따라서, 도심지에서 개착식 굴착공사를 수행함에 있어서, 계획, 설계 및 시공의 건설 전체 단계에서 굴착공사 붕괴 방지를 위한 철저한 대비가 필요하다. 본 연구에서는 이와 같은 개착식 굴착공사 중 붕괴사고 예방을 위해, 중점적으로 관리되어야 할 우선 요소 결정 연구를 수행하였다. 먼저, 과거 흙막이 굴착공사의 사고사례 조사결과를 분석하고, 전문가 합의에 의한 의사결정 방법인 델파이 기법을 이용하여 붕괴 유발 요소에 대한 중요도를 산정하였다. 그 결과, 지하수 처리, 지반조사의 부실, 시공상의 불안정 등이 흙막이 공사 붕괴 예방을 위한 중점 관리 요소로 도출되었다.

• Journal of Gastric Cancer
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• 제15권3호
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• pp.159-166
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• 2015

Purpose: Laparoscopic total gastrectomy (LTG) is more complicated than laparoscopic distal gastrectomy, especially during a surgeon's initial experience with the technique. In this study, we evaluated the short-term outcomes of and learning curve for LTG during the initial cases of a single surgeon compared with those of open total gastrectomy (OTG). Materials and Methods: Between 2009 and 2013, 134 OTG and 74 LTG procedures were performed by a single surgeon who was experienced with OTG but new to performing LTG. Clinical characteristics, operative parameters, and short-term postoperative outcomes were compared between groups. Results: Advanced gastric cancer and D2 lymph node dissection were more common in the OTG than LTG group. Although the operation time was significantly longer for LTG than for OTG ($175.7{\pm}43.1$ minutes vs. $217.5{\pm}63.4$ minutes), LTG seems to be slightly superior or similar to OTG in terms of postoperative recovery measures. The operation time moving average of 15 cases in the LTG group decreased gradually, and the curve flattened at 54 cases. The postoperative complication rate was similar for the two groups (11.9% vs. 13.5%). No anastomotic or stump leaks occurred. Conclusions: Although LTG is technically difficult and operation time is longer for surgeons experienced in open surgery, it can be performed safely, even during a surgeon's early experience with the technique. Considering the benefits of minimally invasive surgery, LTG is recommended for early gastric cancer.