• 제목/요약/키워드: open cut

검색결과 242건 처리시간 0.024초

개착식 굴착공사 중 지반함몰 위험등급 분류시트의 등급 보정에 관한 연구 (Correction of the Ground Subsidence Risk Ratings during Open Cut Excavation)

  • 신상식;김학준
    • 지질공학
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    • 제31권2호
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    • pp.135-148
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    • 2021
  • 굴착 전 지반조사 결과를 활용한 지반함몰 위험등급 분류는 시공 과정에서 들어나는 인자들에 따라 평가 결과가 다르게 나타날 수 있다. 본 연구에서는 기존 연구에서 제안된 굴착 전 지반조사 결과를 활용한 지반함몰 위험등급 분류 방법을 현장상황을 고려하여 보정하는 방법을 제시하였다. 굴착 진행 중 지하수위는 차수공법의 적용 여부나 시공 상태에 따라 유출되는 정도가 시공 전 예측결과와 다르게 나타난다. 굴착 중 급격한 지하수위 하강은 압밀이나 압축 등의 체적 감소로 지반함몰을 유발하고 집중 호우 등에 의한 수위 상승은 굴착 저면의 히빙이나 보일링을 발생시켜 지반함몰 위험도를 높인다. 굴착 중 흙막이 벽체의 과도한 변위나 지반침하는 지반함몰의 원인이 될 수 있으며, 매설된 관로의 파손을 야기하여 지반함몰 위험도를 높인다. 본 연구에서는 굴착 중 지하수 변동 및 유출상태, 지반변위, 흙의 종류 등을 고려하여 지반함몰 영향인자를 재평가하는 방법을 제안하였다. 최종적으로 지반함몰 평가의 영향인자를 5개 카테고리의 12개 영향인자로 평가할 수 있도록 개선하였다.

Mechanical model for analyzing the water-resisting key stratum to evaluate water inrush from goaf in roof

  • Ma, Kai;Yang, Tianhong;Zhao, Yong;Hou, Xiangang;Liu, Yilong;Hou, Junxu;Zheng, Wenxian;Ye, Qiang
    • Geomechanics and Engineering
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    • 제28권3호
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    • pp.299-311
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    • 2022
  • Water-resisting key stratum (WKS) between coal seams is an important barrier that prevents water inrush from goaf in roof under multi-seam mining. The occurrence of water inrush can be evaluated effectively by analyzing the fracture of WKS in multi-seam mining. A "long beam" water inrush mechanical model was established using the multi-seam mining of No. 2+3 and No. 8 coal seams in Xiqu Mine as the research basis. The model comprehensively considers the pressure from goaf, the gravity of overburden rock, the gravity of accumulated water, and the constraint conditions. The stress distribution expression of the WKS was obtained under different mining distances in No. 8 coal seam. The criterion of breakage at any point of the WKS was obtained by introducing linear Mohr strength theory. By using the mechanical model, the fracture of the WKS in Xiqu Mine was examined and its breaking position was calculated. And the risk of water inrush was also evaluated. Moreover, breaking process of the WKS was reproduced with Flac3D numerical software, and was analyzed with on-site microseismic monitoring data. The results showed that when the coal face of No. 8 coal seam in Xiqu Mine advances to about 80 m ~ 100 m, the WKS is stretched and broken at the position of 60 m ~ 70 m away from the open-off cut, increasing the risk of water inrush from goaf in roof. This finding matched the result of microseismic analysis, confirming the reliability of the water inrush mechanical model. This study therefore provides a theoretical basis for the prevention of water inrush from goaf in roof in Xiqu Mine. It also provides a method for evaluating and monitoring water inrush from goaf in roof.

Extracorporeal Cardiopulmonary Resuscitation in Infants: Outcomes and Predictors of Mortality

  • Byeong A Yoo;Seungmo Yoo;Eun Seok Choi;Bo Sang Kwon;Chun Soo Park;Tae-Jin Yun;Dong-Hee Kim
    • Journal of Chest Surgery
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    • 제56권3호
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    • pp.162-170
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    • 2023
  • Background: Extracorporeal cardiopulmonary resuscitation (E-CPR) plays an indispensable role when resuscitation fails; however, extracorporeal life support (ECLS) in infants is different from that in adults. The objective of this study was to evaluate the outcomes of E-CPR in infants. Methods: A single-center retrospective study was conducted, analyzing 51 consecutive patients (age <1 year) who received E-CPR for in-hospital cardiac arrest between 2010 and 2021. Results: The median age and body weight was 51 days (interquartile range [IQR], 17-111 days) and 3.4 kg (IQR, 2.9-5.1 kg), respectively. The cause of arrest was cardiogenic in 45 patients (88.2%), and 48 patients (94.1%) had congenital cardiac anomalies. The median conventional cardiopulmonary resuscitation (C-CPR) time before the initiation of ECLS was 77 minutes (IQR, 61-103 minutes) and duration of ECLS was 7 days (IQR, 3-12 days). There were 36 in-hospital deaths (70.6%), and another patient survived after heart transplantation. In the multivariate analysis, single-ventricular physiology (odds ratio [OR], 5.05; p=0.048), open sternum status (OR, 8.69; p=0.013), and C-CPR time (OR, 1.47 per 10 minutes; p=0.021) were significant predictors of in-hospital mortality. In a receiver operating characteristic curve, the optimal cut-off of C-CPR time was 70.5 minutes. The subgroup with early E-CPR (C-CPR time <70.5 minutes) showed a tendency for lower in-hospital mortality tendency (54.5% vs. 82.8%, p=0.060), albeit not statistically significant. Conclusion: If resuscitation fails in an infant, E-CPR could be a life-saving option. It is crucial to improve C-CPR quality and shorten the time before ECLS initiation.

지하철공사에서 풍화대용 쉴드 TBM의 경암 구간 굴진 시 대체공법에 대한 사례연구 (A Case Study on Penetrating Hard Rock with Alternative Methods of Shield TBM for Weathered Layer in Subway Construction)

  • 박형근;고원근
    • 대한토목학회논문집
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    • 제30권6D호
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    • pp.623-629
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    • 2010
  • 최근 도심지 굴착 시 고효율 급속시공이 가능한 쉴드 TBM(Tunnel Boring Machine) 공법의 도입이 점진적으로 증가하고 있다. 그러나 해당 장비에 대한 이해부족과 현지 지반조건을 충분히 고려하지 않은 상태로 쉴드 TBM의 설계 및 선정시 시공능력의 저하, 시공기간의 연장 및 공사비의 증가를 초래하는 경우가 빈번히 발생되고 있다. 이에 따라 본 사례연구에서는 풍화토, 풍화암 굴착에 적합하도록 설계된 쉴드 TBM 터널 굴착현장을 대상으로 쉴드 TBM 굴진 시 사전 지반조사의 결과와 달리 예기치 못한 경암구간 돌출로 굴진 중단 및 공기지연을 최소화하고자 적용된 대체공법의 적용성을 비교 분석하였다. 또, 터널 상 하행선 경암굴착에 적용된 대체공법의 선정부터 적용 후 결과에서 얻어진 굴진자료와 쉴드장비의 굴진속도, 공사기간, 공사비 등을 검토하여 연구대상 현장에 가장 적합한 대체공법을 판단 및 평가하였다. 본 연구의 결과를 요약하면 다음과 같다. 첫째, 굴진중단 및 대체공법 적용으로 인한 공사비, 공사기간의 증가를 방지하려면 대상현장의 정확한 지반조사가 선행되어야 하며, 이를 바탕으로 현장 지반조건에 가장 적합한 쉴드장비를 선정하는 것이 중요하다. 둘째, 대상현장에서 시행한 대체공법의 적용성을 분석한 결과, 경암구간 굴착을 위한 대체공법의 최선안은 개착 공법 후 경암 발파제거 공법임을 알 수 있었다.

Quality of Radiomics Research on Brain Metastasis: A Roadmap to Promote Clinical Translation

  • Chae Jung Park;Yae Won Park;Sung Soo Ahn;Dain Kim;Eui Hyun Kim;Seok-Gu Kang;Jong Hee Chang;Se Hoon Kim;Seung-Koo Lee
    • Korean Journal of Radiology
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    • 제23권1호
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    • pp.77-88
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    • 2022
  • Objective: Our study aimed to evaluate the quality of radiomics studies on brain metastases based on the radiomics quality score (RQS), Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD) checklist, and the Image Biomarker Standardization Initiative (IBSI) guidelines. Materials and Methods: PubMed MEDLINE, and EMBASE were searched for articles on radiomics for evaluating brain metastases, published until February 2021. Of the 572 articles, 29 relevant original research articles were included and evaluated according to the RQS, TRIPOD checklist, and IBSI guidelines. Results: External validation was performed in only three studies (10.3%). The median RQS was 3.0 (range, -6 to 12), with a low basic adherence rate of 50.0%. The adherence rate was low in comparison to the "gold standard" (10.3%), stating the potential clinical utility (10.3%), performing the cut-off analysis (3.4%), reporting calibration statistics (6.9%), and providing open science and data (3.4%). None of the studies involved test-retest or phantom studies, prospective studies, or cost-effectiveness analyses. The overall rate of adherence to the TRIPOD checklist was 60.3% and low for reporting title (3.4%), blind assessment of outcome (0%), description of the handling of missing data (0%), and presentation of the full prediction model (0%). The majority of studies lacked pre-processing steps, with bias-field correction, isovoxel resampling, skull stripping, and gray-level discretization performed in only six (20.7%), nine (31.0%), four (3.8%), and four (13.8%) studies, respectively. Conclusion: The overall scientific and reporting quality of radiomics studies on brain metastases published during the study period was insufficient. Radiomics studies should adhere to the RQS, TRIPOD, and IBSI guidelines to facilitate the translation of radiomics into the clinical field.

목질(木質)의 열수추출(熱水抽出) 및 CaCl2 첨가(添加)가 목질(木質)-세멘트 보드의 휨강도(强度) 및 팽윤율(膨潤率)에 미치는 영향(影響) (The Effects of Hot Water Extraction of Wood Meal and the Addition of CaCl2 on Bending Strength and Swelling Ratio of Wood-Cement Board)

  • 안원영;신동소;최돈하
    • Journal of the Korean Wood Science and Technology
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    • 제13권3호
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    • pp.49-53
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    • 1985
  • The effects of pre-treatments, the hot water extraction of wood meal and the addition of chemical ($CaCl_2$) to wood-cement water system on the properties of wood-cement composite such as modulus of rupture (MOR), modulus of elasticity (MOE), water sorption ratio and swelling ratio of resulting boards were studied in this experiment. The wood meals through 0.83mm(20 mesh) and retained on 0.42mm(35 mesh) screen were prepared from Pinus densiflora S. at Z. and Larix leptolepsis G. For hot water extraction, 500 grams of wood meal for each species were heated to boiling with 1,500ml of distilled water in 2-liter beaker for 6 hours. Every 2 hours, the wood meals were washed with boiling distil1ed water and reheated to boiling again. After 6 hours boiling, the boiled wood particles were collected by pouring this particles on 200 mesh screen. The collected particles then washed twice with hot distilled water and dried for 24 hours in an oven at $109{\pm}20^{\circ}C$. A mixture of 663.4 grams of cement with 331.7 grams of wood meal based on oven-dry weight were dry-mixed in a plastic vessel. The mixture was kneaded with 497.6ml of distilled water in the ratio of 1.5ml of water to a gram of wood meal. To add calcium chloride to the mixture as an accelerator, $CaCl_2$ 4% solution by weight per volume, was added to pine-or larch-cement board in the ratio of 3% to cement weight. To set wood-cement board, this mixture was clamped at 30cm ${\times}$ 30cm, in thickness of 1.5cm for 3 days at room temperature, declamped and then placed at open condition for 17 days. The target density was 1.0. The four specimens sized to 5cm in width and 28cm in length were used for MOR and MOE test for each treatment. After MOR test, the tested specimens were cut to the size of 5cm ${\times}$ 5cm for water sorption and swelling test. The twenty specimens used to measure the water sorption ratio (soaking 24 hours) and ten of these were used for swelling ratio measurement The results obtained were as follows: 1) Larch was not suitable for wood-cement boards because larch-cement board developed no strength, but pine showed 97.9kg/$cm^2$ by hot water extraction. 2) To increase MOR, hot water extraction was more effective than the addition of $CaCl_2$ in pine and larch because the $CaCl_2$ addition was seemed to speed up the ratio of cement hydration without reacting with the wood substances. 3) The water sorption ratio was lowered by the addition of $CaCl_2$ to wood-cement system because the chemical additive accelerated the rate of cement hydration. 4) In pine-cement board, the swelling ratio from 0.37 to 0.42 percent was observed in length and the swelling ratio from 0.88 to 2.0 percent in thickness. As a rule, the swelling ratio of wood-cement board was very low and the swelling ratio in thickness was higher than in length.

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취입모의 경제적 계획취입수심 산정방법에 대한 연구 (A Study on a Calculation Method of Economical Intake Water Depth in the Design of Head Works)

  • 김철기
    • 한국농공학회지
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    • 제20권1호
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    • pp.4592-4598
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    • 1978
  • The purpose of this research is to find out mathemetically an economical intake water depth in the design of head works through the derivation of some formulas. For the performance of the purpose the following formulas were found out for the design intake water depth in each flow type of intake sluice, such as overflow type and orifice type. (1) The conditional equations of !he economical intake water depth in .case that weir body is placed on permeable soil layer ; (a) in the overflow type of intake sluice, {{{{ { zp}_{1 } { Lh}_{1 }+ { 1} over {2 } { Cp}_{3 }L(0.67 SQRT { q} -0.61) { ( { d}_{0 }+ { h}_{1 }+ { h}_{0 } )}^{- { 1} over {2 } }- { { { 3Q}_{1 } { p}_{5 } { h}_{1 } }^{- { 5} over {2 } } } over { { 2m}_{1 }(1-s) SQRT { 2gs} }+[ LEFT { b+ { 4C TIMES { 0.61}^{2 } } over {3(r-1) }+z( { d}_{0 }+ { h}_{0 } ) RIGHT } { p}_{1 }L+(1+ SQRT { 1+ { z}^{2 } } ) { p}_{2 }L+ { dcp}_{3 }L+ { nkp}_{5 }+( { 2z}_{0 }+m )(1-s) { L}_{d } { p}_{7 } ] =0}}}} (b) in the orifice type of intake sluice, {{{{ { zp}_{1 } { Lh}_{1 }+ { 1} over {2 } C { p}_{3 }L(0.67 SQRT { q} -0.61)}}}} {{{{ { ({d }_{0 }+ { h}_{1 }+ { h}_{0 } )}^{ - { 1} over {2 } }- { { 3Q}_{1 } { p}_{ 6} { { h}_{1 } }^{- { 5} over {2 } } } over { { 2m}_{ 2}m' SQRT { 2gs} }+[ LEFT { b+ { 4C TIMES { 0.61}^{2 } } over {3(r-1) }+z( { d}_{0 }+ { h}_{0 } ) RIGHT } { p}_{1 }L }}}} {{{{+(1+ SQRT { 1+ { z}^{2 } } ) { p}_{2 } L+dC { p}_{4 }L+(2 { z}_{0 }+m )(1-s) { L}_{d } { p}_{7 }]=0 }}}} where, z=outer slope of weir body (value of cotangent), h1=intake water depth (m), L=total length of weir (m), C=Bligh's creep ratio, q=flood discharge overflowing weir crest per unit length of weir (m3/sec/m), d0=average height to intake sill elevation in weir (m), h0=freeboard of weir (m), Q1=design irrigation requirements (m3/sec), m1=coefficient of head loss (0.9∼0.95) s=(h1-h2)/h1, h2=flow water depth outside intake sluice gate (m), b=width of weir crest (m), r=specific weight of weir materials, d=depth of cutting along seepage length under the weir (m), n=number of side contraction, k=coefficient of side contraction loss (0.02∼0.04), m2=coefficient of discharge (0.7∼0.9) m'=h0/h1, h0=open height of gate (m), p1 and p4=unit price of weir body and of excavation of weir site, respectively (won/㎥), p2 and p3=unit price of construction form and of revetment for protection of downstream riverbed, respectively (won/㎡), p5 and p6=average cost per unit width of intake sluice including cost of intake canal having the same one as width of the sluice in case of overflow type and orifice type respectively (won/m), zo : inner slope of section area in intake canal from its beginning point to its changing point to ordinary flow section, m: coefficient concerning the mean width of intak canal site,a : freeboard of intake canal. (2) The conditional equations of the economical intake water depth in case that weir body is built on the foundation of rock bed ; (a) in the overflow type of intake sluice, {{{{ { zp}_{1 } { Lh}_{1 }- { { { 3Q}_{1 } { p}_{5 } { h}_{1 } }^{- {5 } over {2 } } } over { { 2m}_{1 }(1-s) SQRT { 2gs} }+[ LEFT { b+z( { d}_{0 }+ { h}_{0 } )RIGHT } { p}_{1 }L+(1+ SQRT { 1+ { z}^{2 } } ) { p}_{2 }L+ { nkp}_{5 }}}}} {{{{+( { 2z}_{0 }+m )(1-s) { L}_{d } { p}_{7 } ]=0 }}}} (b) in the orifice type of intake sluice, {{{{ { zp}_{1 } { Lh}_{1 }- { { { 3Q}_{1 } { p}_{6 } { h}_{1 } }^{- {5 } over {2 } } } over { { 2m}_{2 }m' SQRT { 2gs} }+[ LEFT { b+z( { d}_{0 }+ { h}_{0 } )RIGHT } { p}_{1 }L+(1+ SQRT { 1+ { z}^{2 } } ) { p}_{2 }L}}}} {{{{+( { 2z}_{0 }+m )(1-s) { L}_{d } { p}_{7 } ]=0}}}} The construction cost of weir cut-off and revetment on outside slope of leeve, and the damages suffered from inundation in upstream area were not included in the process of deriving the above conditional equations, but it is true that magnitude of intake water depth influences somewhat on the cost and damages. Therefore, in applying the above equations the fact that should not be over looked is that the design value of intake water depth to be adopted should not be more largely determined than the value of h1 satisfying the above formulas.

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무화과 발효물의 급여가 한우의 생산성, 혈액성상 및 육질에 미치는 영향 (The Effects of Fig Fermented Product Supplementation on Animal Performance, Serum Profile and Meat Quality in Hanwoo Bulls)

  • 국길;김광현
    • Journal of Animal Science and Technology
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    • 제44권6호
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    • pp.739-746
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    • 2002
  • 본 연구는 한우 수소 10두를 공시하여 전남 영암군의 지역특산물인 무화과 열매와 잎를 발효시킨 발효물을 10% 첨가하여 출하전 8개월간 급여하였을 때 생산성, 혈액성상, 도체성적 및 육질특성을 조사하였다. 한우 수소에 무화과 발효물 10%을 급여했을때 사료섭취량은 무화과 발효물 급여구가 대조구에 비해 약간 증가하였으나, 종료체중과 일당증체량에서는 처리구간에 유의적인 차이는 나타내지 않았다. 혈액성상은 처리구간에 유의적인 차이는 없었다. 도체성적에서는 육량등급에는 처리간에 차이는 없었으나 육질등급에서 무화과 발효물 급여구에서 근내지방도가 유의적(P<0.05)으로 증가하여 육질등급 개선 효과가 있었다. 산육성적은 처리간에 유의적인 차이가 없었다. 등심의 이화학적 특성으로 조지방 함량이 무화과 발효물 급여구에서 유의적(P<0.05)으로 증가하였다. 물리적 특성에서는 pH와 육색, 가열감량에는 처리간에 유의적인 차이는 없었으나, 전단력과 cholesterol 함량은 무화과 발효물 급여구에서 유의적(P<0.05)으로 감소하였다. 지방산 조성에서는 등심부위에서 리놀레인산이 무화과 발효물 급여구에서 유의적(P< 0.05)으로 증가하였으며 무화과 발효물 급여구의 등심부위 피하지방에서 C16:0이 유의적(P< 0.05)으로 감소한 반면 C18:1는 유의적(P<0.05)으로 증가하였다. 따라서 무화과 발효물 급여구에서 포화지방산이 유의적(P<0.05)으로 감소한 반면에 불포화지방산은 유의적(P<0.05)으로 증가하였다. 관능평가에서는 냄새는 무화과 발효물 급여구에서 약간 개선되었으며 외관과 맛에 있어서는 무화과 발효물 급여구에서 유의적(P<0.05)으로 증가하였다. 이상의 결과, 무화과 열매와 잎을 발효시킨 발효물을 한우 수소에 급여시 도체등급 향상에 따른 축산농가의 생산성 향상과 더불어 한우고기의 연도개선과 저콜레스테롤 그리고 외관과 맛에 차별화로 고급육생산에 효과가 있는 것으로 사료된다.

상지(上肢) 외전위(外轉位)에서 시행(施行)한 쇄골상(鎖骨上) 상완신경총차단(上腕神經叢遮斷) (Supraclavicular Brachial Plexus block with Arm-Hyperabduction)

  • 임권;임화택;김동권;박오;김성열;오흥근
    • The Korean Journal of Pain
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    • 제1권2호
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    • pp.214-222
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    • 1988
  • With the arm in hyperabduction, we have carried out 525 procedures of supraclavicular brachial plexus block from Aug. 1976 to June 1980, whereas block with the arm in adduction has been customarily performed by other authors. The anesthetic procedure is as follows: 1) The patient lies in the dorsal recumbent position without a pillow under his head or shoulder. His arm is hyperabducted more than a 90 degree angle from his side, and his head is turned to the side opposite from that to be blocked. 2) An "X" is marked at a point 1 cm above the mid clavicle, immediately lateral to the edge of the anterior scalene muscle, and on the palpable portion of the subclavian artery. The area is aseptically prepared and draped. 3) A 22 gauge 3.5cm needle attached to a syringe filled with 2% lidocaine (7~8mg/kg of body weight) and epineprine(1 : 200,000) is inserted caudally toward the second portion of the artery where it crosses the first rib and parallel with the lateral border of the muscle until a paresthesia is obtained. 4) Paresthesia is usually elicited while inserting the needle tip about 1~2 em in depth. If so, the local anesthetic solution is injected after careful aspiration. 5) If no paresthesia is elicited, the needle is withdrawn and redirected in an attempt to elicit paresthesia. 6) If, after several attempts, no paresthesia is obtained, the local anesthetic solution is injected into the perivascular sheath after confirming that the artery is not punctured. 7) Immediately after starting surgery, Valium is injected for sedation by the intravenous route in almost all cases. The age distribution of the cases was from 11 to 80 years. Sex distribution was 476 males and 49 females (Table 1). Operative procedures consisted of 103 open reductions, 114 skin grafts combined with spinal anesthesia in 14, 87 debridements, 75 repairs, i.e. tendon (41), nerve(32), and artery (2), 58 corrections of abnormalities, 27 amputations above the elbow (5), below the elbow (3) and fingers (17), 20 primary closures, 18 incisions and curettages, 2 replantations of cut fingers. respectively (Table 2). Paresthesia was obtained in all cases. Onset of analgesia occured within 5 minutes, starting in the deltoid region in almost all cases. Complete anesthesia of the entire arm appeared within 10 minutes but was delayed 15 to 20 minutes in 5 cases and failed in one case. Thus, our success rate was nearly 100%. The duration of anesthesia after a single injection ranged from $3\frac{1}{2}$ to $4\frac{1}{2}$, hours in 94% of the cases. The operative time ranged from 0.5 to 4 hours in 92.4% of the cases(Table 3). Repeat blocks were carried out in 33 cases when operative times which were more than 4 hours in 22 cases and the others were completed within 4 hours (Table 4). Two patients of the 33 cases, who received microvasular surgery were injected twice with 2% lidocaine 20 ml for a total of $13\frac{1}{2}$ hours. The 157 patients who received surgery on the forearms or hands had pneumatic tourniquets (250 torrs) applied without tourniquet pain. There was no pneumothorax, hematoma or phrenic nerve paralysis in any of the unilateral and 27 bilateral blocks, but there was hoarseness in two, Horner's syndrome in 11 and shivering in 7 cases. No general seizures or other side effects were observed. By 20ml of 60% urcgratin study, we confirm ed the position of the needle tip to be in a safer position when the arm is in hyperabduction than when it is in adduction. And also that the humoral head caused some obstraction of the distal flow of the dye, indicating that less local anesthetic solution would be needed for satisfactory anesthesia. (Fig. 3,4).

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폐 결절에서 FDG-PET의 유용성과 표준섭취계수와 혈당농도의 상관관계 (Utility of FDG-PET in Solitary Pulmonary Nodules and the Relationship Between Standardized Uptake Values of PET and Serum Glucose)

  • 김규식;임성철;고영춘;박경화;주진영;조계중;김수옥;오인재;김유일;김영철;김성민;송호천;범희승;박경옥
    • Tuberculosis and Respiratory Diseases
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    • 제55권6호
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    • pp.589-596
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    • 2003
  • 연구배경 : 고립성 폐 결절의 양성과 악성의 감별은 치료와 예후를 결정하는데 중요하지만 결핵성 육아종의 빈도가 높은 국내에서는 감별진단이 쉽지가 않다. 이에 저자들은 최근 고립성 폐 결절의 진단에 정확성이 높다고 알려진 PET의 유용성과 혈당농도와 결절의 표준섭취계수의 차이를 알아보고자 하였다. 방 법 : 2001년 1월부터 2002년 6월까지 전남대학교 의과대학병원에서 시행한 단순 흉부사진상 발견된 고립성 폐 결절과 타 병원에서 이를 주소로 내원한 환자들 중 FDG-PET 및 조직학적인 검사로 진단된 61명의 환자를 대상으로 하였다. 결 과 : 조직학적으로 진단된 61례에서 악성 결절은 48례(편평상피세포폐암 23례, 선암 16례, 소세포폐암 9례), 양성 결절은 13례(염증성 육아종 9례, 결핵종 3례, cryptococcosis 증 l례) 이었다. 침상형을 가진 경우는 모두 악성 결절을 보였으나 분엽성과 침상형을 모두 갖지 않은 경우에서도 악성 결절을 보여 이러한 결절의 변연으로 악성과 양성 결절을 명확히 구분할 수 없었다. PET의 경우 SUV cut-off value를 3.0으로 하였을 때 13례의 양성 결절 중 10례에서 3.0 이하의 수치를 보였으며 3례에서 SUV가 3.0 이상으로 증가되었다. 악성 결절 48례는 모두 SUV가 3.0 이상의 값을 보였다. 악성 결절의 평균 SUV는 $9.52{\pm}5.20$, 양성 결절은 $1.61{\pm}3.60$으로 두 군간에 의의 있게 차이를 보였다. 폐암 환자에서 당뇨병을 가진 환자 군과 당뇨병이 없는 군의 평균 SUV에선 $9.10{\pm}4.51$, $9.65{\pm}5.46$으로 두 군 사이에 차이를 보이지 않았다. FDG-PET 검사의 민감도, 특이도, 양성 예측치 및 음성 예측치는 100%, 77%, 94% 및 100%의 결과를 보여 다른 검사에 비하여 진단적 정확성은 높았으나 상대적으로 특이도는 낮았다. 결 론 : 고립성 폐 결절에 대해 FDG-PET 진단검사는 비침습적인 검사로 다른 검사에 비하여 높은 정확도를 보여 주고 있으며 혈중 포도당 농도에 영향을 받지 않는 것으로 생각되고 있다. 특이도가 낮은점은 결핵종 등이 많은 우리나라에서 더 많은 연구가 이루어져야 할 것으로 생각된다.