• Title/Summary/Keyword: open clusters

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Cloning and Characterization of Homeodomain-Zip Gene, Phc5 in Embryogenic Callus derived from Pimpinella brachycarpa Suspension Cultured Cells (참나물 현탁배양세포 유래 배발생캘러스에서 HD-Zip 유전자, Phc5의 클로닝과 특성)

  • 손수인;김준철
    • Korean Journal of Plant Tissue Culture
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    • v.26 no.2
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    • pp.121-126
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    • 1999
  • Calli were induced from the petiole explants of Pimpinella brachycarpa on MS medium supplemented with 0.5 mg/L 2,4-D and 0.1 mg/L BA after four weeks of culture. Compact clusters of small and dense cells among these calli were selected and suspension-cultured as the source of embryogenic calli. When transferred to MS medium with 0.1 mg/L NAA, the suspension-cultured cells grew to embryogenic callus. Somatic embryos derived from these embryogenic calli developed into plantlets. The cDNA library was constructed in the embryogenic callus and in order to screen the cDNA library, these cDNAs were plated at a density 1.5 $\times$ 10^5 plaques per 15 cm petridish. Among 19 clones showing preferential hybridization with petiole HD-Zip gene, five clones were obtained after second screening. Four clones among them, were highly homologous to P. brachycarpa shoot-tip Phz4 gene, but one clone, Phc5 was about 1.5 kb which has an extra 163 bp to 5' upstream of Phz4. The Phc5 was 1,531 bp containing poly A tails of 18 bases. ATG start codon for Phc5, was located at position 284 with an open reading frame of 906 by which encodes a polypeptide of 302 amino acids. The Phc5 protein revealed that the polypeptides between 135 and 195 contain a homeodomain as the `leucine zipper' motif.

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An Investigation on Intellectual Structure of Social Sciences Research by Analysing the Publications of ICPSR Data Reuse (ICPSR 데이터 재이용 저작물 분석을 통한 사회과학 분야의 지적구조 분석)

  • Chung, EunKyung
    • Journal of the Korean Society for Library and Information Science
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    • v.52 no.1
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    • pp.341-357
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    • 2018
  • Due to the paradigm of open science and advanced digital information technology, data sharing and re-use have been actively conducted and considered data-intensive in a wide variety of disciplines. This study aims to investigate the intellectual structure portrayed by the research products re-using the data sets from ICPSR. For the purpose of this study, a total of 570 research products published in 2017 from the ICPSR site were collected and analyzed in two folds. First, the authors and publications of those research products were analyzed in order to show the trends of research using ICPSR data. Authors tend to be affiliated with university or research institute in the United States. The subject areas of journals are recognized into Social Sciences, Health, and Psychology. In addition, a network with clustering analysis was conducted with using co-word occurrence from the titles of the research products. The results show that there are 12 clusters, mental health, tabocco effect, disorder in school, childhood, and adolescence, sexual risk, child injuries, physical activity, violent behavior, survey, family role, women, problem behavior, gender differences in research areas. The structure portrayed by ICPSR data re-uses demonstrates that substantial number of studies in Medicine have been conducted with a perspective of social sciences.

A Study on Green Space Location Selection to Reduce Particulate Matter by Projecting Distributions of Emission Source and Vulnerable Groups - focusing on Seongdong-gu, Seoul - (미세먼지 배출원과 취약계층 분포 추정을 통한 미세먼지 저감 녹지 입지 선정 연구 - 서울시 성동구를 대상으로 -)

  • Shin, Ye-Eun;Park, Jin-Sil;Kim, Su-Yeon;Lee, Sang-Woo;An, Kyung-Jin
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.24 no.1
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    • pp.53-68
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    • 2021
  • The study aims to propose a locating method of green space for reducing Particulate Matter (PM) in ambient air in conjunction with its source traces and vulnerable groups. In order to carry out the aims and purposes, a literature review was conducted to derive indicators of vulnerable area to PM. Based on the developed indicators, the vulnerable areas and green spaces creation strategies for each cluster were developed for the case of Seongdong-gu, Seoul. As a result, six indicators for vulnerability analysis were came out including the vulnerable groups (children's facilities, old people's facilities), emission sources (air pollutant emission workplaces, roads), and environmental indicators (particulate matter concentration, NDVI). According to the six selected indicators, the target area was divided into 39 hexagons and analyzed to result the most vulnerable areas to particulate matter. As a result of comprehensive vulnerability analysis, the Seongsu-dong area was found to be the most vulnerable to particulate matter, and 5 clusters were derived through k-means cluster analysis. Cluster 1 was analyzed as areas that most vulnerable to particulate matter as a result of the comprehensive analysis, therefore urgent need to create green spaces to reduce particulate matter. Cluster 2 was areas that mostly belonged to the Han River. Cluster 3 corresponds to the largest number of hexagons, and since many vulnerable groups are distributed, it was analyzed as a cluster that required the creation of a green spaces to reduce particulate matter, focusing on facilities for vulnerable groups. Three hexagons are included in cluster 4, and the cluster has many roads and lacks vegetation in common. Cluster 5 has a lot of green spaces and is generally distributed with fewer vulnerable groups and emission sources; however, it has a high level of particulate matter concentration. In a situation where various green spaces creation projects for reducing particulate are being implemented, it is necessary to consider the vulnerable groups and emission sources and to present green space creation strategies for each space characteristic in order to increase the effectiveness of such projects. Therefore, this study is regarded as meaningful in suggesting a method for selecting a green area for reducing PM.

An Exploratory Study on the Applicability of Semantic Web Technology in the Process of Using Culture and Arts Materials (문화예술자료의 활용 체계에서 시맨틱 웹 기술 적용에 관한 탐색적 연구)

  • Im, Youngsook;Yim, Haksoon
    • Korean Association of Arts Management
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    • no.58
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    • pp.205-239
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    • 2021
  • This study explores the importance of semantic web-based network construction in art data archiving, as well as its meaning and value in the context of arts management along with its potential for future application. The study focuses on oral history obtained from the Arko Arts Archives that contained records of the lives and artistic views of early artists. In this study, the possibility of applying semantic web-based technology to materials concerning culture and the arts was discussed in five aspects based on the results of the case analysis. First, checking the relationship and discovering hidden artists are possible by revealing relationships between characters. Second, understanding and studying society and culture at a given time is possible by interpreting the contextual meaning of information. Third, art exploration can be done broadly and deeply, encompassing various genres from the perspective of the consumer. Fourth, through art construction, history can be reconstructed using a new and rich method. Fifth, expanding the scope beyond the boundaries of art is possible through convergence and collaboration of programs that handle big data. The network data can be used in various methods, such as art history research, art planning, and creation, throughout the art ecosystem. The results of the study suggest that digitizing a large quantity of data concerning culture and the arts is meaningful in arts management as well as identifying and analyzing the relationship network among data clusters using semantic web-based technology.

Analysis of a Compound-Target Network of Oryeong-san (오령산 구성성분-타겟 네트워크 분석)

  • Kim, Sang-Kyun
    • Journal of the Korea Knowledge Information Technology Society
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    • v.13 no.5
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    • pp.607-614
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    • 2018
  • Oryeong-san is a prescription widely used for diseases where water is stagnant because it has the effect of circulating the water in the body and releasing it into the urine. In order to investigate the mechanisms of oryeong-san, we in this paper construct and analysis the compound-target network of medicinal materials constituting oryeong-san based on a systems pharmacology approach. First, the targets related to the 475 chemical compounds of oryeong-san were searched in the STITCH database, and the search results for the interactions between compounds and targets were downloaded as XML files. The compound-target network of oryeong-san is visualized and explored using Gephi 0.8.2, which is an open-source software for graphs and networks. In the network, nodes are compounds and targets, and edges are interactions between the nodes. The edge is weighted according to the reliability of the interaction. In order to analysis the compound-target network, it is clustered using MCL algorithm, which is able to cluster the weighted network. A total of 130 clusters were created, and the number of nodes in the cluster with the largest number of nodes was 32. In the clustered network, it was revealed that the active compounds of medicinal materials were associated with the targets for regulating the blood pressure in the kidney. In the future, we will clarify the mechanisms of oryeong-san by linking the information on disease databases and the network of this research.

From Industrial Clusters to Innovation Districts: Metropolitan Industrial Innovations and Governance (산업클러스터에서 혁신지구로: 도시의 산업혁신과 거버넌스)

  • Keebom Nahm
    • Journal of the Economic Geographical Society of Korea
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    • v.26 no.3
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    • pp.169-189
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    • 2023
  • The study aims to synthesize the discussion of the innovation district and suggest an alternative to the governance system of the innovation district. Cluster policies that focus on industrial specialization, networking, value chains, and industrial ecosystems have shown some problems and limits in advanced industrial economies. The innovation district, suitable for the era of urban innovation, convergence of industry, housing, leisure, and related variety, emphasizes cooperation through the convergence of various innovations, workshops and industries, and communities. It is important to build a quintuple helix based on cooperative governance through public-private partnerships, integrate the physical and cultural atmosphere, and service industries that strengthen the place prestige. Beyond the industrial aspect, innovation districts can facilitate changes in urban amenities and lifestyles and creative atmosphere, such as diversity, lifestyle, charms, and openness, and promote social vitality and economic interactions. The governance of innovative districts can promote inter-organizational exchanges, and combinations. When knowledge is created through exchanges between companies, it also affects changes in the governance system, evolving from a rigid and centralized system to an open, dynamic, and organic system. Through the innovation policy, the existing Central Business Districts (CBD) can be able to be transformed into a Central Lifestyle Districts (CLD).

Benthic Macroinvertebrates Inhabiting Estuaries in Sea Area and Relationship with Major Drivers of Change in Estuaries (해역별 하구에 서식하는 저서성 대형무척추동물 현황과 하구 서식지 주요 변화 동인과의 관계)

  • Lim, Sung-Ho;Jung, Hyun-Chul;Lee, Min-Hyuk;Lee, Sang-Wook;Moon, Jeong-Suk;Kwon, Soon-Hyun;Won, Du-Hee
    • Korean Journal of Ecology and Environment
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    • v.55 no.1
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    • pp.10-18
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    • 2022
  • This study analyzed the relationship between the community structure of benthic macroinvertebrates and habitat changes in open estuaries among the sites included in the national estuary monitoring program. The estuary survey was conducted under the "Guidelines for Investigation and Evaluation of Biometric Networks" and classified by sea area, 80 places in the East Sea, 102 places in the South Sea, and 19 places in the West Sea were investigated. In a total of 201 open estuaries, benthic macroinvertebrates were identified with 4 phyla, 9 classes, 41 orders, 139 families, 269 species and 196 species in the East Sea, 182 species in the South Sea, and 90 species in the West Sea. The highest population densities were Insecta in the East Sea, the Malacostraca in the South Sea, and the Annelida in the West Sea. Through SIMPER analysis, species contributing to the similarity of benthic macroinvertebrates communities in each sea area were identified. Some species greatly influenced the similarity of clusters. The benthic community in the East Sea was affected by the salinity, so the contribution rate of freshwater species was high. On the other hand, the benthic communities of the South and West Seas showed species compositions are influenced by the substrate composition. As results, the benthic macroinvertebrate community in Korean estuaries was impacted by salinity and substrate simultaneously, and the close relationship with geographical distance was not observed. The result of this study is expected to be used to respond to environmental changes by identifying and predicting changes in the diversity and distribution of benthic macroinvertebrates in Korea estuaries.

Anthropometric Measurement, Dietary Behaviors, Health-related Behaviors and Nutrient Intake According to Lifestyles of College Students (대학생의 라이프스타일 유형에 따른 신체계측, 식행동, 건강관련 생활습관 및 영양소 섭취상태에 관한 연구)

  • Cheong, Sun-Hee;Na, Young-Joo;Lee, Eun-Hee;Chang, Kyung-Ja
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.36 no.12
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    • pp.1560-1570
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    • 2007
  • The purpose of this study was to investigate the differences according to lifestyle in anthropometric measurement, dietary attitude, health-related behaviors and nutrient intake among the college students. The subjects were 994 nation-wide college students (male: 385, female: 609) and divided into 7 clusters (PEAO: passive economy/appearance-oriented type, NCPR: non-consumption/pursuit of relationship type, PTA: pursuit of traditional actuality type, PAT: pursuit of active health type, UO: utility-oriented type, POF: pursuit of open fashion type, PFR: pursuit of family relations type). A cross-sectional survey was conducted using a self administered questionnaire, and the data were collected via Internet or by mail. The nutrient intake data collected from food record were analyzed by the Computer Aided Nutritional Analysis Program. Data were analyzed by a SPSS 12.0 program. Average age of male and female college students were 23.7 years and 21.6 years, respectively. Most of the college students had poor eating habits. In particular, about 60% of the PEAO group has irregularity in meal time. The students in PAH and POF groups showed significantly higher consumption frequency of fruits, meat products and foods cooked with oil compared to the other groups. As for exercise, drinking and smoking, there were significant differences between PAH and the other groups. Asked for the reason for body weight control, 16.2% of NCPR group answered "for health", but 24.8% of PEAO group and 26.3% of POF group answered "for appearance". Calorie, vitamin A, vitamin $B_2$, calcium and iron intakes of all the groups were lower than the Korean DRIs. Female students in PTA group showed significantly lower vitamin $B_1$ and niacin intakes compared to the PFR group. Therefore, these results provide nation-wide information on health-related behaviors and nutrient intake according to lifestyles among Korean college students.