• Journal of KIISE
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• v.42 no.8
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• pp.998-1009
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• 2015

In recent years, there has been a growing interest in RDFS Inference to build a rich knowledge base. However, it is difficult to improve the inference performance with large data by using a single machine. Therefore, researchers are investigating the development of a RDFS inference engine for a distributed computing environment. However, the existing inference engines cannot process data in real-time, are difficult to implement, and are vulnerable to repetitive tasks. In order to overcome these problems, we propose a method to construct an in-memory distributed inference engine that uses a parallel graph structure. In general, the ontology based on a triple structure possesses a graph structure. Thus, it is intuitive to design a graph structure-based inference engine. Moreover, the RDFS inference rule can be implemented by utilizing the operator of the graph structure, and we can thus design the inference engine according to the graph structure, and not the structure of the data table. In this study, we evaluate the proposed inference engine by using the LUBM1000 and LUBM3000 data to test the speed of the inference. The results of our experiment indicate that the proposed in-memory distributed inference engine achieved a performance of about 10 times faster than an in-storage inference engine.

• Journal of the Korea Society of Computer and Information
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• v.15 no.1
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• pp.31-42
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• 2010

GPM(Generic Product Model) developed by Hitachi in Japan is a common data model to integrate and share life cycle data of nuclear power plants. GPM consists of GPM core model, an abstract model, implementation language for the model and reference library written in the language. GPM core model has a feature that it can construct a semantic network model consisting of relationships among objects. Initial GPM developed and provided GPML as an implementation language to support the feature of the core model, but afterwards the GPML was replaced by GPM-XML based on XML to achieve data interoperability with heterogeneous applications accessing a GPM data model. However, data models written in GPM-XML are insufficient to be used as a semantic network model for lack of studies which support GPM-XML and enable the models to be used as a semantic network model. This paper proposes OWL as the implementation language for GPM core model because OWL can describe ontologies similar to semantic network models and has an abundant supply of technical standards and supporting tools. Also, OWL which can be expressed in terms of RDF/XML based on XML guarantees data interoperability. This paper uses OWL DL, one of three sublanguages of OWL, because it can guarantee complete reasoning and the maximum expressiveness at the same time. The contents of this paper introduce the way how to overcome the difference between GPM and OWL DL, and, base on this way, describe how to convert the reference library written in GPML into ontologies based on OWL DL written in RDF/XML.

• The Korean Journal of Archival Studies
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• no.54
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• pp.81-109
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• 2017

This study suggests an analysis of the reviews provided by international archival professionals on the RiC-CM draft published by ICA EGAD. Some implications for the Korean archival management environment were also suggested. Some professional reviews were accessible through the internet. Italian archival professionals held workshops at various levels for the analysis and discussion of the draft. Duranti, the project director of InterPARES, also gave opinions about the draft in cluding the perspective of digital preservation. In the review of Artefactual, the draft was discussed in terms of system implementation. Reed, the director of Recordkeeping Innovation, also gave a feedback based on the record management experiences in Australia. Some implications can be suggested based on these professional opinions. First, we should try to build a test bed for the adoption of RiC to archival description in the Korean environment. Second, a minimum level of data elements that can secure authenticity and integrity will also be needed. Third and lastly, rich authority data for agents and functions related to archival records and records groups are essential to take full advantage of the standard.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.1
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• pp.537-545
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• 2018

In this study, transcriptome analysis was conducted to collect various information from Fagopyrum esculentum and Fagopyrum tataricum during the early germination stage. Total RNA was extracted from the seeds and at 12, 24, and 36 hrs after germination of Jeju native Fagopyrum esculentum and Fagopyrum tataricum and sequenced using the Illumina Hiseq 2000 platform. Raw data analysis was conducted using the Dynamic Trim and Lengths ORT programs in the SolexaQA package, and assembly and annotation were performed. Based on RNA-seq raw data, we obtained 16.5 Gb and 16.2 Gb of transcriptome data corresponding to about 84.2% and 81.5% of raw data, respectively. De novo assembly and annotation revealed 43,494 representative transcripts corresponding to 47.5Mb. Among them, 23,165 sequences were shown to have similar sequences with annotation DB. Moreover, Gene Ontology (GO) analysis of buckwheat representative transcripts confirmed that the gene is involved in metabolic processes (49.49%) of biological processes, as well as cell function (46.12%) in metabolic process, and catalytic activity (80.43%) in molecular function In the case of gibberellin receptor GID1C, which is related to germination of seeds, the expression levels increased with time after germination in both F. esculentum and F. tataricum. The expression levels of gibberellin 20-oxidase 1 were increased within 12 hrs of gemination in F. esculentum but continuously until 36 hrs in F. tataricum. This buckwheat transcriptome profile analysis of the early germination stage will help to identify the mechanism causing functional and morphological differences between species.

• Asia pacific journal of information systems
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• v.19 no.1
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• pp.33-62
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• 2009

Internet computing is a disruptive IT innovation. Semantic Web can be considered as an IT innovation because the Semantic Web technology possesses the potential to reduce information overload and enable semantic integration, using capabilities such as semantics and machine-processability. How should organizations adopt the Semantic Web? What factors affect the adoption and diffusion of Semantic Web innovation? Most studies on adoption and diffusion of innovation use empirical analysis as a quantitative research methodology in the post-implementation stage. There is criticism that the positivist requiring theoretical rigor can sacrifice relevance to practice. Rapid advances in technology require studies relevant to practice. In particular, it is realistically impossible to conduct quantitative approach for factors affecting adoption of the Semantic Web because the Semantic Web is in its infancy. However, in an early stage of introduction of the Semantic Web, it is necessary to give a model and some guidelines and for adoption and diffusion of the technology innovation to practitioners and researchers. Thus, the purpose of this study is to present a model of adoption and diffusion of the Semantic Web and to offer propositions as guidelines for successful adoption through a qualitative research method including multiple case studies and in-depth interviews. The researcher conducted interviews with 15 people based on face-to face and 2 interviews by telephone and e-mail to collect data to saturate the categories. Nine interviews including 2 telephone interviews were from nine user organizations adopting the technology innovation and the others were from three supply organizations. Semi-structured interviews were used to collect data. The interviews were recorded on digital voice recorder memory and subsequently transcribed verbatim. 196 pages of transcripts were obtained from about 12 hours interviews. Triangulation of evidence was achieved by examining each organization website and various documents, such as brochures and white papers. The researcher read the transcripts several times and underlined core words, phrases, or sentences. Then, data analysis used the procedure of open coding, in which the researcher forms initial categories of information about the phenomenon being studied by segmenting information. QSR NVivo version 8.0 was used to categorize sentences including similar concepts. 47 categories derived from interview data were grouped into 21 categories from which six factors were named. Five factors affecting adoption of the Semantic Web were identified. The first factor is demand pull including requirements for improving search and integration services of the existing systems and for creating new services. Second, environmental conduciveness, reference models, uncertainty, technology maturity, potential business value, government sponsorship programs, promising prospects for technology demand, complexity and trialability affect the adoption of the Semantic Web from the perspective of technology push. Third, absorptive capacity is an important role of the adoption. Fourth, suppler's competence includes communication with and training for users, and absorptive capacity of supply organization. Fifth, over-expectance which results in the gap between user's expectation level and perceived benefits has a negative impact on the adoption of the Semantic Web. Finally, the factor including critical mass of ontology, budget. visible effects is identified as a determinant affecting routinization and infusion. The researcher suggested a model of adoption and diffusion of the Semantic Web, representing relationships between six factors and adoption/diffusion as dependent variables. Six propositions are derived from the adoption/diffusion model to offer some guidelines to practitioners and a research model to further studies. Proposition 1 : Demand pull has an influence on the adoption of the Semantic Web. Proposition 1-1 : The stronger the degree of requirements for improving existing services, the more successfully the Semantic Web is adopted. Proposition 1-2 : The stronger the degree of requirements for new services, the more successfully the Semantic Web is adopted. Proposition 2 : Technology push has an influence on the adoption of the Semantic Web. Proposition 2-1 : From the perceptive of user organizations, the technology push forces such as environmental conduciveness, reference models, potential business value, and government sponsorship programs have a positive impact on the adoption of the Semantic Web while uncertainty and lower technology maturity have a negative impact on its adoption. Proposition 2-2 : From the perceptive of suppliers, the technology push forces such as environmental conduciveness, reference models, potential business value, government sponsorship programs, and promising prospects for technology demand have a positive impact on the adoption of the Semantic Web while uncertainty, lower technology maturity, complexity and lower trialability have a negative impact on its adoption. Proposition 3 : The absorptive capacities such as organizational formal support systems, officer's or manager's competency analyzing technology characteristics, their passion or willingness, and top management support are positively associated with successful adoption of the Semantic Web innovation from the perceptive of user organizations. Proposition 4 : Supplier's competence has a positive impact on the absorptive capacities of user organizations and technology push forces. Proposition 5 : The greater the gap of expectation between users and suppliers, the later the Semantic Web is adopted. Proposition 6 : The post-adoption activities such as budget allocation, reaching critical mass, and sharing ontology to offer sustainable services are positively associated with successful routinization and infusion of the Semantic Web innovation from the perceptive of user organizations.

• Clinical and Experimental Reproductive Medicine
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• v.33 no.2
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• pp.125-132
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• 2006

Objective: In the previous study, we complied the differentially expressed genes during early folliculogenesis. Objective of the present study was to identify downstream target genes of transcription factors (TFs) using bioinformatics for selecting the target TFs among the gene lists for further functional analysis. Materials & Methods: By using bioinformatics tools, constituent domains were identified from database searches using Gene Ontology, MGI, and Entrez Gene. Downstream target proteins/genes of each TF were identified from database searches using TF database ($TRANSFAC^{(R)}$ 6.0) and eukaryotic promoter database (EPD). Results: DNA binding and trans-activation domains of all TFs listed previously were identified, and the list of downstream target proteins/genes was obtained from searches of TF database and promoter database. Based on the known function of identified downstream genes and the domains, 3 (HNF4, PPARg, and TBX2) out of 26 TFs were selected for further functional analysis. The genes of wee1-like protein kinase and p21WAF1 (cdk inhibitor) were identified as potential downstream target genes of HNF4 and TBX2, respectively. PPARg, through protein-protein interaction with other protein partners, acts as a transcription regulator of genes of EGFR, p21WAF1, cycD1, p53, and VEGF. Among the selected 3 TFs, further study is in progress for HNF4 and TBX2, since wee1-like protein kinase and cdk inhibitor may involved in regulating maturation promoting factor (MPF) activity during early folliculogenesis. Conclusions: Approach used in the present study, in silico analysis of downstream target genes, was useful for analyzing list of TFs obtained from high-throughput cDNA microarray study. To verify its binding and functions of the selected TFs in early folliculogenesis, EMSA and further relevant characterizations are under investigation.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.5
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• pp.836-847
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• 2020

Objective: We investigated the temporal expression profiles of long noncoding RNA (lncRNA) and mRNA in the peripheral blood of pigs during development and identified the lncRNAs that are related to the blood-based immune system. Methods: Peripheral blood samples were obtained from the pigs at 0, 7, 28, and 180 days and 2 years of age. RNA sequencing was performed to survey the lncRNA and mRNA transcriptomes in the samples. Short time-series expression miner (STEM) was used to show temporal expression patterns in the mRNAs and lncRNAs. Gene ontology and Kyoto encyclopedia of genes and genomes analyses were performed to assess the genes' biological relevance. To predict the functions of the identified lncRNAs, we extracted mRNAs that were nearby loci and highly correlated with the lncRNAs. Results: In total of 5,946 lncRNA and 12,354 mRNA transcripts were identified among the samples. STEM showed that most lncRNAs and mRNAs had similar temporal expression patterns during development, indicating the expressional correlation and functional relatedness between them. The five stages were divided into two classes: the suckling period and the late developmental stage. Most genes were expressed at low level during the suckling period, but at higher level during the late stages. Expression of several T-cell-related genes increased continuously during the suckling period, indicating that these genes are crucial for establishing the adaptive immune system in piglets at this stage. Notably, lncRNA TCONS-00086451 may promote blood-based immune system development by upregulating nuclear factor of activated T-cells cytoplasmic 2 expression. Conclusion: This study provides a catalog of porcine peripheral blood-related lncRNAs and mRNAs and reveals the characteristics and temporal expression profiles of these lncRNAs and mRNAs during peripheral blood development from the newborn to adult stages in pigs.

• Journal of Intelligence and Information Systems
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• v.15 no.1
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• pp.87-102
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• 2009

With the growth of Web 2.0, lots of services allow yours to post their personal information and useful knowledges on networked information spaces such as blogs and online communities etc. As the services are generalized, recent researches related to social network have gained momentum. However, most social network services do not support machine-processable semantic knowledge, so that the information cannot be shared and reused between different domains. Moreover, as explicit definitions of relationships between individual social entities do not be described, it is difficult to analyze social network for inferring unknown semantic relationships. To overcome these limitations, in this paper, we propose a social network analysis system with personal photographic data up-loaded by virtual community users. By using ontology, an informative connectivity between a face entity extracted from photo data and a person entity which already have social relationships was defined clearly and semantic social links were inferred with domain rules. Then the inferred links were provided to yours as a visualized graph. Based on the graph, more efficient social network analysis was achieved in online community.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.2
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• pp.187-196
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• 2020

Objective: Porcine respiratory disease is one of the most important health problems causing significant economic losses. To understand the genetic basis for susceptibility to swine enzootic pneumonia (EP) in pigs, we detected 102,809 single nucleotide polymorphisms in a total of 249 individuals based on genome-wide sequencing data. Methods: Genome comparison of susceptibility to swine EP in three pig breeds (Jinhua, Erhualian, and Meishan) with two western lines that are considered more resistant (Duroc and Landrace) using cross-population extended haplotype homozygosity and F-statistic (F_ST) statistical approaches identified 691 positively selected genes. Based on quantitative trait loci, gene ontology terms and literature search, we selected 14 candidate genes that have convincible biological functions associated with swine EP or human asthma. Results: Most of these genes were tested by several methods including transcription analysis and candidate genes association study. Among these genes: cytochrome P450 1A1 and catenin beta 1 (CTNNB1) are involved in fertility; transforming growth factor beta receptor 3 plays a role in meat quality traits; Wnt family member 2, CTNNB1 and transcription factor 7 take part in adipogenesis and fat deposition simultaneously; plasminogen activator, urokinase receptor (completely linked to AXL receptor tyrosine kinase, r² = 1) plays an essential role in the successful ovulation of matured oocytes in pigs; colipase like 2 (strongly linked to SAM pointed domain containing ETS transcription factor, r² = 0.848) is involved in male fertility. Conclusion: These adverse genes susceptible to swine EP may be selected while selecting for economic traits (especially reproduction traits) due to pleiotropic and hitchhiking effect of linked genes. Our study provided a completely new point of view to understand the genetic basis for susceptibility or resistance to swine EP in pigs thereby, provides insight for designing sustainable breed selection programs. Finally, the candidate genes are crucial due to their potential roles in respiratory diseases in a large number of species, including human.

• Journal of KIISE:Software and Applications
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• v.36 no.3
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• pp.187-199
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• 2009

With the advent of Web 2.0, OpenAPIs are becoming an increasing trend to emphasize Web as platform recently. OpenAPIs are used to combine services and generate new services by mashup. However because the standard documents for OpenAPIs do not exist, it may restrict the use of OpenAPIs. Previous studies of OpenAPIs mashup have been limited to tool design or language definition for service combination rather than dynamic composition. On the other hand, Web services that are a software technology implementing SOA provide standard documents such as WSDL to explain each service, UDDI to register it, and SOAP to transfer messages. Thus Web applications can interpret and execute services by using these technologies. Recent works have also been performed to provide semantic features and dynamic composition for SOA. If a dynamic and systematic approach is provided to combine Web services and OpenAPIs, Web applications can provide users with diverse services. In this study, we present a SOA based framework for mashup of OpenAPIs and Web services. The framework supports dynamic composition of OpenAPIs and Web services, where the process of composite services is described in OWL-S. A prototype is provided to validate our framework. The framework is expected to add diversity to typical Web services.