• Korean Institute of Interior Design Journal
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• v.20 no.5
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• pp.208-216
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• 2011

Today, the market environment for companies around the world has been changed by globalization, digital innovation, information by opening the diversity, consumer awareness, and the development of mass media in the wide areas such as, politics, economy, society and culture. Accordingly, the function of the housing cultural center also has been changed from the Place where the trading had been made to the Space where the marketing could work. The housing cultural center is home to companies to target their corporate culture and corporate image, and the brand identity. From the space marketing standpoint, this study extracts differentiator of the housing cultural center from theoretical consideration to boom up of the housing cultural center and to build up its identification. Based on this analysis, the design identity element of the interior design of the housing cultural center is proposed by the actual and analytical cases. Such a future plan design identity elements in the design of the new housing cultural center is providing basic design guide line to recognize the importance.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2009.01a
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• pp.290-293
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• 2009

In this paper, we propose a method to estimate pointing region in real-world from images of cameras. In general, arm-pointing gesture encodes a direction which extends from user's fingertip to target point. In the proposed work, we assume that the pointing ray can be approximated to a straight line which passes through user's face and fingertip. Therefore, the proposed method extracts two end points for the estimation of pointing direction; one from the user's face and another from the user's fingertip region. Then, the pointing direction and its target region are estimated based on the 2D-3D projective mapping between camera images and real-world scene. In order to demonstrate an application of the proposed method, we constructed an ICGS (interactive cinema guiding system) which employs two CCD cameras and a monitor. The accuracy and robustness of the proposed method are also verified on the experimental results of several real video sequences.

• Journal of Educational Research in Mathematics
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• v.9 no.1
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• pp.321-332
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• 1999

This article made overtures of the relationship between interactive mathematics texts nd the prototype design of computer application with Computer Algebra System Math. Engine, linking together in the school mathematics. School teachers and researchers would try to construct mathematical materials with computers in educating students in the middle and high school grades. As the individual users come to manage hyper-media materials, so they meet with the problem of 'Who does control?'A mass user would be concerned with interactive mathematics materials directly or off-line at realtime and manipulate the process of problem-solving symbolically with MathView/sup 11)/ and ON-Math/sup 12)/. Discussion was made in developing the factor in the domestic situation and reaching out their hands for it. In conclusion, a user may reform the information of math-curriculum limitedly.

• Journal of Dairy Science and Biotechnology
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• v.17 no.1
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• pp.39-49
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• 1999

Since IMF relief financing, domestic economy has been rapidly cooled down. At this point that we predict an overall decrease of production and sale of industries, cooperative marketing activities of the whole dairy industry are required to promote milk consumption. As everyone knows, advertisement is only one of the various factors that affect sales. Other factors include price, distribution, package, promotion, and consumer's needs and taste. The objectives of the cooperative advertising campaign should be trial purchase of new consumers, maintenance of brand loyalty of existing consumers, more positive experience of using the product, and increase of frequency of purchase. Long term analysis is essential to making these kinds of behaviour changes. Also the objectives of the communication program should be a shift of awareness of milk from 'a basic health food for children' to a substitute to the beverage even for adults. To share database of consumers among companies, we need to find ways to use interactive on-line services, the internet, D.M. events and so on as well as the mass media. It should be a precondition that the main body of the cooperative advertisement includes the milk processing board, dairy companies, livestock cooperations, farmers and the Government. To assure continuous, activities to promote milk consumption, the Government should take the lead in legislating 'An enforcement ordinance for milk promotion and research', and seek complementary measures and support to establish the ordinance.

• Advances in Traditional Medicine
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• v.3 no.1
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• pp.34-39
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• 2003

We investigated the immune enhancement effects of JaSaengHwan (JSH). The forced swimming test (FST) has been used as a screening model for new immune enhancement agents. We found that JSH (0.1 mg/ml) significantly reduced the immobility time in the FST compared to the control. Also, we investigated the effect of JSH on the proliferation of T cell and production of cytokines in human T-cell line, MOLT-4 cells and mouse peritoneal macrophages. JSH (1 mg/ml) significantly increased the cell proliferation by $46.78{\pm}6.41%$ (p<0.05) and also significantly increased the interleukin (IL)-2, IL-4 and interferon $(IFN)-{\gamma}$ production compared with media control (about 2-fold for IL-2, 3-fold for IL-4 and 1.5-fold for $IFN-{\gamma}$, p<0.05) at 24 h. In addition, JSH increased the production of IL-12 on the mouse peritoneal macrophages (by 3.6-fold for IL-12, p<0.05). In conclusion, these data indicate that JSH may have an immune-enhancement effect.

• The KIPS Transactions:PartA
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• v.13A no.6 s.103
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• pp.555-560
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• 2006

In contrast with the earlier remote education that simply recorded off-line classes, modern remote education emphasizes on offering additional functions that could maximize learning efficiency. Usage of such multimedia information as the texts, graphics, sounds, animations is considered fundamental element in offering the additional functions. This paper designs and implements an encoder/decoder that could accommodate the multimedia information with emphasis on demonstrating execution files. Instructors can demonstrate my type of execution files or application data files, and the remote learners can freely try running the corresponding execution files by themselves. Consequently, a high-level of learning efficiency can be achieved by the proposed encoder/decoder.

• Journal of the Korea Society of Computer and Information
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• v.23 no.4
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• pp.71-80
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• 2018

In this paper, we developed an interactive animation authoring tool and developed the Android based interactive edutainment contents. The authoring tool for creating interactive animations developed in this paper is based on a graphical user interface, so users can easily create interactive animations. Interactive animation contents created by this authoring tool can be created as images and xml files so that they can be used directly on mobile devices. In order to increase learning efficiency for children, Android-based interactive edutainment electronic storybooks, which is implemented using this authoring tool, provided a recording function to listen to the parents' voice as well as an interactive action in which the characters move in accordance with the story line. We also provided a STEAM game that combines creativity and imagination with creative science and technology. Therefore, by creating the edutainment contents through the proposed authoring tool for interactive animation, various interactive animation contents could be produced more easily than the code implementation method. Through this study, I hope that it will be helpful for the development of various interactive edutainment contents to provide educational contents considering the quantity and quality to infants.

• Journal of Distribution Science
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• v.19 no.1
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• pp.49-60
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• 2021

Purpose: A good physical appearance greatly affects a person's self-confidence, especially when the media constantly depicts that beautiful men and women are those with perfect bodies, which later forms the perception that being fat or too thin is not attractive. That is in line with the increasing knowledge and the need for nutritious foods and drinks for diets. Therefore, this study aims to see whether there is a relationship between the Weight Rejuvenation Program Everyday product innovation towards millennial purchase decision and the motivation of having an ideal body as a moderating effect. Research design, data, and methodology: Distributed online Google form questionnaires to 96 audiences who commented on "Mute" web series. The respondents consisted of 63 women and 33 men from the millennial generation who lived in Greater Jakarta and were classified as the middle to upper economic class. After all of the data were collected, they were processed using Structural Equation Modeling Partial Least Squares. Results: Product innovation had a significant influence on the purchasing decisions of the millennial consumer, but motivation did not have the moderating function in the relationships between product innovation and purchase decision. Conclusions: The main factor for product innovation that can be accepted by millennials is the product quality that remains good.

• Radiation Oncology Journal
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• v.17 no.1
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• pp.70-77
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• 1999

Purpose : The expression of p53, P211WAF/CIP, Bcl-2, and Bax underlying the radiation-induced apoptosis in different pH environments using SCK mammary adenocarcinoma cell line was investigated. Materials and Methods Mammary adenocarcinoma cells of hi) mice (SCK cells) in exponential growth phase were irradiated with a linear accelerator at room temperature. The cells were irradiated with 12 Gy and one hour later, the media was replaced with fresh media at a different pHs. After Incubation at 37Microbioiogy, College of Medicine Dong A University for 0$\~$48 h, the extort of apoptosis was determined using agarose gel electrophoresis and flow cytometry. The progression of cells through the cell cycle after irradiation in different pHs was also determined with flow cytometry. Western blot analysis was used to monitor p53, p211WAFfCIP, Bcl-2, and Bu protein levels. Results : The induction of apoptosis by irradiation in pH 6.6 medium was markedly less than that in pH 7.5 medium. The radiation-induced G2IM arrest in pH 6.6 medium lasted markedly longer than that in pH 7.5 medium. Considerable amounts of p53 and p21 proteins already existed at pH 7.5 and increased the level of p53 and p21 significantly after 12 Gy X-irradiation. An incubation at pH 6.6 after 12 Gy X-irradiation did not change the level of p53 and p21 protein levels significantly. Bcl-2 proteins were not significantly affected by radiation and showed no correlation with cell susceptibility to radiation-induced apoptosis in different pHs. An exposure to 12 Gy of X-rays increased the level of Bax protein at pH 7.5 but at pH 6.6, it was slight. Conclusions : The molecular mechanism underlying radiation-induced apoptosis in dinerent pH environments using SCK mammary adenocarcinoma cell line was dependent of the expression p53 and P211YVAF/CIP proteins. We may propose following hypothesis that an acidic stress augments the radiation-induced G2iM arrest, which inhibiting the irradiated cells undergo post-mitotic apoptosis. The effects of environmental acidity on anti-apoptotic and pro-apoptotic function of Bcl-2 family was unclear in SCK mammary adenocarcinoma cell line.

• Journal of Radiation Protection and Research
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• v.43 no.2
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• pp.66-74
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• 2018

Background: Tumor response to anticancer therapies can much be influenced by microenvironmental factors. In this study, we determined the effect of these microenvironmental factors on DNA methylation using A549 human lung adenocarcinoma cell line. Materials and Methods: We subjected A549 cells to various conditions mimicking tumor microenvironment including hypoxia, acidosis (sodium lactate), oxidative stress ($H_2O_2$), bystander effect (supernatant from doxorubicin (Dox)-treated or irradiated cells), and immune cell infiltration (supernatant from THP-1 or Jurkat T cells). Genomic DNA was isolated from these cells and analyzed for DNA methylation. Clonogenic cell survival, gene expression, and metabolism were analyzed in cells treated with some of these conditions. Results and Discussion: We found that DNA methylation level was significantly decreased in A549 cells treated with conditioned media from Dox-treated cells or Jurkat T cells, or sodium lactate, indicating an active transcription. To determine whether the decreased DNA methylation affects radiation sensitivity, we exposed cells to these conditions followed by 6 Gy irradiation and found that cell survival was significantly increased by sodium lactate while it was decreased by conditioned media from Dox-treated cells. We further observed that cells treated with conditioned media from Dox-treated cells exhibited significant changes in expression of genes including BAX and FAS (involved in apoptosis), NADPH dehydrogenase (mitochondria), EGFR (cellular survival) and RAD51 (DNA damage repair) while sodium lactate increased cellular metabolism rather than changing the gene expression. Conclusion: Our results suggest that various tumor microenvironmental factors can differentially influence DNA methylation and hence radiosensitivity and gene expression in A549 cancer cells.