• Title/Summary/Keyword: omega-3

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Clinical safety and efficacy of a novel marine source of the long-chain omega-3 fatty acids

  • Park, Joung-Hyun;Musa-Veloso, Kathy;Ji, Ho-Seok
    • Journal of Marine Bioscience and Biotechnology
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    • v.14 no.1
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    • pp.43-50
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    • 2022
  • Squid is a sustainable source of long-chain omega 3 fatty acids. This study aims to assess the safety and triglyceride-lowering efficacy of refined oil derived from the squid(Todarodes pacificus) viscera. Male and female participants with elevated fasting serum lipids (i.e., total cholesterol of ≥5.2 mmol/L or fasting serum triglyceride of ≥1.65 mmol/L) were randomly allocated to the control (n = 52) or squid oil group (n = 52), and participants in the latter group were instructed to consume 3 g of squid oil daily for 60 days. None of the subjects reported adverse events associated with the consumption of squid oil. Baseline clinical chemistry and hematological parameter values and those toward the end of the treatment period were similar, and all values were within the normal range. Fasting cholesterol and triglyceride levels in the control and squid oil groups were similar; however, toward the end of the 60 day study period, these levels significantly reduced in the squid oil group relative to those in the control group (P< 0.01). However, high-density lipoprotein-cholesterol remained unchanged in both groups. Thus, it can be inferred that squid oil is a safe source of long-chain omega-3 fatty acids and has beneficial effects on the blood lipid levels. This is the first clinical study on squid oil usage, and suggests that it could be a sustainable source of omega 3 fatty acids.

The Study on Vigor and External Factors of Tree in Damaged Pine Stands by Thecodiplosis japonensis Uchida et Inouye (솔잎혹파리 피해임지내 수목의 외형적 인자와 관련한 수세변동과정 해석)

  • Lee, Chan-Yong;Kim, Joung-Kuk;Chae, Hee-Mun;Lee, Sang-Bae;Won, Dae-Sung
    • Journal of Forest and Environmental Science
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    • v.18 no.1
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    • pp.45-52
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    • 2001
  • This paper investigated external factors (height. crown width. diameter breath height, clear length) of tree and electric resistance ($k{\Omega}$) in damaged forest by Thecodiplosis japonensis Uchida et Inouye. The height. crown width and diameter breath height of tree external factors have high a coefficient of correlation. but clear length has not a coefficient of correlation. In relationship of electric resistance and external factor. big tree that height. crown width. diameter breath height has lower electric resistance value than that of small tree. (low electric resistance value is high tree vigor, high electric resistance value is low tree vigor)) Dead tree have smaller diameter breath height. crown width. higher clear length than survival tree in damaged forest by Thecodiplosis japonensis Uchida et Inouye. To investigation of relationship external factors according to electric resistance value. electric resistance value was divided three class (< $l4k{\Omega}$, possible of survival. $14{\sim}20k{\Omega}$, > $20k{\Omega}$, possible of dead). In lower class(< $l4k{\Omega}$), external factors have bigger which was height. crown width. diameter breath height and lower which was clear length than them of higher class ($14{\sim}20k{\Omega}$, > $20k{\Omega}$). Linear regression solutions of electric resistance and external factors were Y = -0.572 ${\times}$ Height - 1.163 ${\times}$ crown width - 0.242 ${\times}$ diameter breath height + 0.757 ${\times}$ clear length + 25.765. Regression solutions were significant in 5%.

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Fatty Acid Intake, Serum Fatty acid Composition and Serum Se Concentration of Elementary School Children in Korea (우리나라 일부 초등학생의 지방산 섭취양상과 혈청 지방산 및 Selenium 수준에 관한 연구)

  • 이양자
    • Journal of Nutrition and Health
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    • v.32 no.7
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    • pp.802-811
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    • 1999
  • The purposes of this study were to 1) examine the dietary patterns of fatty acids and the fatty acid composition in serum, 2) determine selenium (Se) concentrations, and 3) investigate how serum fatty acid compositon affects serum levels of Se in Korean elementary school children. The subjects consisted of 168 school children(82 boys & 86 girls) belonging to 1st through 6th grades, and their dietary assessment was evaluated. The serum fatty acid composition was analyzed by GLC, and the ICP/MS method was employed to measure serum Se concentration. Total average intake of PUFA, MUFA and SFA were 10.5g, 12.7g, 11.2g respectively. Total average dietary P/M/S ratio was 1.10/1.18/1.0. The average intake of $\omega$3 fatty acids and $\omega$6 fatty acids were 1.33g, 9.19g, respectively. The $\omega$6/$\omega$3ratio was 14.2 which is higher than the recommended range. In serum fatty acid composition, PUFA, MUFA, SFA were 40.6%, 28.1% and 31.6% respectively. The average $\omega$3 fatty acid composition was 3.80%, and the mean value of $\omega$6 series was 36.8%. The M/S ratio of girls was significantly higher than boy's in fatty acids intake and in serum composition. Mean Se concentration of total subjects was 416.7ug/l and it was significantly higher in the lower grades(1st-3rd)than in the upper grades(4th~6th, p<0.05). Although the mean serum Se concentration was negatively correlated with PUFA composition in total boys and girls, it was not significant. Serum Se concentration was negatively correlated with P/S ratio and C24:1 concentration(p<0.05). In addition, serum composition of $\omega$6 PUFA and C24:1 showed negative correlations with serum Se in only lower grades girl(1st~3rd), and further studies are needed to clarify in these phenomena. In conclusion, the mean serum Se concentration was significantly lower in upper grades (4th~6th)than in lower grades(1st~3rd) of elementary school children and was negatively correlated with P/S ratio of serum fatty acids. More detailed studies on relationship between Se and fatty acids are required.

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Pd/Si/Ti/Pt Ohmic Contact for Application to AlGaAs/GaAs HBT (AIGaAs/GaAs HBT 응용을 위한 Pd/Si/Ti/Pt 오믹 접촉)

  • 김일호;박성호(주)가인테크
    • Journal of the Korean Vacuum Society
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    • v.10 no.3
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    • pp.368-373
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    • 2001
  • Pd/Si/Ti/Pt ohmic contact to n-type InGaAs was investigated. As-deposited contact showed non-ohmic behavior, and high specific contact resistivity of $5\times10^{-3}\Omega\textrm{cm}^2$ was achieved by rapid thermal annealing at $375^{\circ}C$ for 10 seconds. However, the specific contact resistivity decreased remarkably to $1.7\times10^{-6}\Omega\textrm{cm}^2$ and $2\times10^{-6}\Omega\textrm{cm}^2$ at $375^{\circ}C$/60sec and $425^{\circ}C$/10sec, respectively. Superior ohmic contact and non-spiking planar interface between ohmic materials and InGaAs were maintained even at $450^{\circ}C$, therefore, this thermally stable ohmic contact system is a promising candidate for compound semiconductor devices.

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Effect of Supplement of Korean Pinenut Oil on Plasma Total Fatty Acid Composition in Cholesterol-fed Rabbits (한국산 잣기름이 콜레스테롤 첨가식이로 사육한 토끼의 혈장 총지방산 조정에 미치는 영향)

  • Yoon, Tai-Heon
    • Journal of the Korean Applied Science and Technology
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    • v.11 no.1
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    • pp.17-26
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    • 1994
  • The present study was carried out in atheroscleorotic New Zealend white(NZW) rabbits. to evaluate the effect of dietary supplementation with Korean pinenut oil, on plasma total fatty acid composition. In study I, NZW rabbits were fed 10 weeks on a commercial chow diet supplemented with 5% of energy as fats(soybean oil or pinenut oil) or 10% of energy as fats(soybean oil or pinenut oil) with the addition of 1% cholesterol to the diet. Nineteen fatty acids ranged from myristic acid (14:0) to cervonic acid (22:6 ${\omega}3$) were identified in all the samples. The c5, c9, $c12{\sim}18$ : 3 acid was not reported in the fatty acid methyl ester profiles of each group because it was included in the linoleic acid peak. The major constitutent fatty acids in the chow diet group were linoleic acid, oleic acid, palmitic acid and ${\alpha}$-linolenic acid. In the cholesterol group, oleic acid, linoleic acid and palmitic acid were the major fatty acids. In plasma of cholesterol-fed animals, the levels of 16:1 ${\omega}$ 7 and 18:1 1 ${\omega}$ 9 were increased. Linoleic acid was the major fatty acid in soybean oil/cholesterol and pinenut oil/cholesterol groups. Plasma linoleic acid levels were significantly incresed from 4 to 6% by the supplementation of 5% soybean or 5% pinenut oil in the cholesterol diet for 5 weeks, compared to cholesterol group. Plasma 16 : 1 ${\omega}$ 7 levels in animals fed with 5 or 10% pinenut oils were significantly lower than in those fed cholesterol for 5 weeks. After 10 weeks on the soybean oil and pinenut oil diet there were no significant differences in the fatty acid composition. In study II, the fatty acid composition was not affected by the types or levels of oils supplemented for 5 weeks. After 10 weeks on the oil diets 16:1 ${\omega}$ 7 and 18:1 ${\omega}$ 9 were decreased in 10% soybean in oil/cholesterol and 10% pinenut oil/cholesterol groups, compared to cholesterol group.

Ni/Si/Ni Ohmic contacts to n-type 4H-SiC (Ni/Si/Ni n형 4H-SiC의 오옴성 접합)

  • Lee, J.H.;Yang, S.J.;Noh, I.H.;Kim, C.K.;Cho, N.I.;Jung, K.H.;Kim, E.D.;Kim, N.K.
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2001.11b
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    • pp.197-200
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    • 2001
  • In this letter, we report on the investigation of Ni/Si/Ni Ohmic contacts to n-type 4H-SiC. Ohmic contacts have been formed by a vacuum annealing and $N_2$ gas ambient annealing method at $950^{\circ}C$ for 10 min. The specific contact resistivity ( $\rho_{c}$ ), sheet resistance($R_s$), contact resistance($R_c$), transfer length($L_T$) were calculated from resistance($R_T$) versus contact spacing(d) measurements obtained from 10 TLM(transmission line method) structures. The resulting average values of vacuum annealing sample were $\rho_{c}=3.8{\times}10^{-5}\Omega cm^{3}$, $R_{c}=4.9{\Omega}$, $R_{T}=9.8{\Omega}$ and $L_{T}=15.5{\mu}m$, resulting average values of another sample were $\rho_{c}=2.29{\times}10^{-4}\Omega cm^{3}$, $R_{c}=12.9{\Omega}$ and $R_{T}=25.8{\Omega}$. The physical properties of contacts were examined using X-Ray Diffraction and Auger analysis, there was a uniform intermixing of the Si and Ni, migration of Ni into the SiC.

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Thermal Degradation of BZO Layer on the CIGS Solar Cells

  • Choi, Pyungho;Kim, Sangsub;Choi, Byoungdeog
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.02a
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    • pp.458-458
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    • 2013
  • We investigated a study on the thermal degradation of boron doped zinc-oxide (BZO) layer which used as a transparent conducting layer on the Cu (In1-xGax) Se2 (CIGS) based thin film solar cells. Devices were annealed under the temperature of $100^{\circ}C$ or 100 hours and then Hall measurement was carried out to characterize the parameters of mobility (${\mu}Hall$), resistivity (${\rho}$), conductivity (${\sigma}$) and sheet resistance (Rsh). The initial values of ${\mu}Hall$, ${\rho}$, ${\sigma}$ and Rsh were $29.3cm^2$/$V{\cdot}s$, $2.1{\times}10^{-3}{\Omega}{\cdot}cm$, $476.4{\Omega}^{-1}{\cdot}cm^{-1}$ and $19.1{\Omega}$/${\Box}$ respectively. After the annealing process, the values were $4.5cm^2$/$V{\cdot}s$, $12.8{\times}10^{-3}{\Omega}{\cdot}cm$, $77.9{\Omega}^{-1}{\cdot}cm^{-1}$ and $116.6{\Omega}$/${\Box}$ respectively. We observed that ${\mu}Hall$ and ${\sigma}$ were decreased, and ${\rho}$ and Rsh were increased. In this study, BZO layer plays an important role of conducting path for electrons generated by incident light onthe CIGS absorption layer. Therefore, the degradation of BZO layer characterized by the parameters of ${\mu}Hall$, ${\rho}$, ${\sigma}$ and Rsh, affect to the cell efficiency.

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ON SEMILOCAL CONVERGENCE OF A MULTIPOINT THIRD ORDER METHOD WITH R-ORDER (2 + p) UNDER A MILD DIFFERENTIABILITY CONDITION

  • Parida, P.K.;Gupta, D.K.;Parhi, S.K.
    • Journal of applied mathematics & informatics
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    • v.31 no.3_4
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    • pp.399-416
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    • 2013
  • The semilocal convergence of a third order iterative method used for solving nonlinear operator equations in Banach spaces is established by using recurrence relations under the assumption that the second Fr´echet derivative of the involved operator satisfies the ${\omega}$-continuity condition given by $||F^{\prime\prime}(x)-F^{\prime\prime}(y)||{\leq}{\omega}(||x-y||)$, $x,y{\in}{\Omega}$, where, ${\omega}(x)$ is a nondecreasing continuous real function for x > 0, such that ${\omega}(0){\geq}0$. This condition is milder than the usual Lipschitz/H$\ddot{o}$lder continuity condition on $F^{\prime\prime}$. A family of recurrence relations based on two constants depending on the involved operator is derived. An existence-uniqueness theorem is established to show that the R-order convergence of the method is (2+$p$), where $p{\in}(0,1]$. A priori error bounds for the method are also derived. Two numerical examples are worked out to demonstrate the efficacy of our approach and comparisons are elucidated with a known result.