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A Case of Pulmonary Hypertension Associated with Portal Hypertension (문맥고혈압에 동반된 폐고혈압 1예)

  • Jun, Byung-Min;Shin, Young-Rok;Kim, Eun-Kyung;Kim, Hyun-Young;Hong, Sang-Bum;Shim, Tae-Sun;Lim, Chae-Man;Koh, Youn-Suck;Kim, Woo-Sung;Kim, Dong-Soon;Kim, Won-Dong;Lee, Sang-Do
    • Tuberculosis and Respiratory Diseases
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    • v.48 no.1
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    • pp.67-71
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    • 2000
  • Since its first description in 1951 by Mantz and Craig, pulmonary hypertension associated with portal hypertension has been observed more frequently. In a recent prospective study Hadengue et al. reported 2 % incidence of pulmonary hypertension in patients with portal hypertension. Thus this simultaneous occurrence can no longer be considered to be coincidental. The etiology remains unclear. It is most likely that vasoactive substances, normally metabolized by the liver, may have gained access to pulmonary circulation through portosystemic collaterals in portal hypertension. In genetically susceptible individuals, these substances could lead to pulmonary hypertension by inducing vasoconstriction or direct toxic damage to the wall of the small pulmonary arteries. A recent case of pulmonary hypertension in a 49-year-old woman with portal hypertension due to liver cirrhosis is reported as well as a review of the literature.

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Syndrome of Inappropriate Secretion of Antidiuretic Hormone Following Adjuvant Chemotherapy with Cisplatin plus Paclitaxel in Non-Small Cell Lung Cancer Patient (보조항암화학치료 후 발생한 항이뇨호르몬분비이상증후군)

  • Baek, Yong-Soo;Ryu, Jeong-Seon;Hong, Seong-Bin;Yoo, Sung-Soo;Yu, Hyung-Kwon;Son, Dong-Wook;Kim, Lucia;Kang, Hye-Sun;Kim, Beom-Joon;Lee, Kyung-Hee;Cho, Jae-Hwa;Yoon, Young-Han;Kwak, Seung-Min;Lee, Hong-Lyeol;Kim, Kwang-Ho
    • Tuberculosis and Respiratory Diseases
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    • v.61 no.6
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    • pp.591-594
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    • 2006
  • We report a case of pulmonary adenocarcinoma complicated by the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) following adjuvant chemotherapy. A 51-year-old woman with stage IIIA adenocarcinoma received left lower lobe lobectomy in July, 2006. And then combination chemotherapy with paclitaxel and cisplatin was given to the patient. In five days after completion of second cycle of the chemotherapy, she visited emergency room because of general weakness and seizure. Her brain MRI was shown to be no evidence of brain metastasis. Serum sodium, urine and plasma osmolarities were 117mEq/L, 589 and 244mOsm/kg, respectively. She was improved with fluid restriction. Although occurrence of SIADH following chemotherapy is rare, physician should give an attention the potential for development of SIADH in the course of chemotherapyin non-small cell lung cancer patient.

A Case of Primary Choriocarcinoma of the Lung (원발성 폐 융모막암종 1예)

  • Cho, Young-Jae;Lee, Sei Won;Lee, Sang Min;Yim, Jae-Joon;Yoo, Chul-Gyu;Han, Sung Koo;Shim, Young-Soo;Kim, Young Whan
    • Tuberculosis and Respiratory Diseases
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    • v.61 no.6
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    • pp.578-584
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    • 2006
  • A primary choriocarcinoma of the lung is extremely rare, and difficult to distinguish from a metastatic choriocarcinoma considering that the lung is also one of the most frequent sites of metastasis. We report a 28-year-old woman patient who was initially misdiagnosed with an ectopic pregnancy and was operated on under the impression of an unidentified malignancy of the lung, which was finally proven to be a choriocarcinoma of the lung. A pelvic examination by a gynecologist, pelvic magnetic resonance imaging and whole body fluorodeoxyglucose positron emission tomography-computed tomography was performed in order to rule out a metastatic choriocarcinoma of the lung. After a curative operation, her serum ${\beta}$-human chorionic gonadotropin (HCG) level, which was highly elevated in the initial evaluation, had decreased dramatically to the normal range. She is currently being followed up regularly without any evidence of recurrence or elevation of her ${\beta}$-HCG level.

A Study on Korean Gender Egalitarianism among High School Students (고등학생의 남녀평등의식에 관한 연구)

  • Kim Ji Yoon;Ahn Chae Soon
    • Child Health Nursing Research
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    • v.6 no.3
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    • pp.329-343
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    • 2000
  • This study was conducted to measure the degree of Korean Gender Egalitarianism among the students from six different high schools(132 girls, 127 boys) in Sunchon si, Chunnam province from Dec. 7th to Dec. 15th in 1999. The survey on gender egalitarianism was done in relation to the public understanding of the subject matter, parents' hug times, and parent's communication skills. Korean gender egalitari- anism scale was standardized by Korea Woman Developmental Institutes in 1999. The data was analyzed by SAS program. Results were as follows: 1) Generally, girls are more conscious of gender egalitariannism than boys(t=-13.79, p<.001). Above all, the younger the students are, the more they feel equal(F=8.01, p<.01). In sibling cases, two sisters have the highest level of gender egalitarianism while two brothers have the lowest level of gender egalitarianism(F=9.20, p<.001). Students who come from religious families are more inclined to demonstrate gender equality(t= 2.42, p<.05). However, there is no difference in relation to the parents' ages or academic background or harmony within the family. 2) There is no difference that girls and boys generally communicate with their parents. In ages, 17 years old students communicate more than 18, 19 with parents(father F=3.97 p<.05ㆍmother F=5.31, p<.01). That is, the younger students can communicate with their mothers more often than the older ones. In sibling cases, two sisters have more openly communication to parents while two brothers have(F=2.84, p<.05). Students communicate with their parents regardless of parents' academic background. But those from the family in harmony have more open chance to communicate than those who are not in hamony(father F=21.66, p<.001ㆍmother F=13.37, p<.001). They can comm -unicate with their parents better when their fathers hug them than when they didn't get hugs(father t=-4.76, p<.001ㆍ mother t= -2.34, p<.05). They can also communicate with their patents better when their mothers hug them once or more than when they didn't get hugs(father t=-3.78, p<.001ㆍmother t=-5.64, p<.001). 3) There is no difference whether the father hugs or not, but the mother's hug is very important because students whose mothers hug them once or more have significantly more gender egalitarianism than those students whose mothers didn't do(t=-3.98, p<.001). Based upon these results, it is recommended that we reconsider the role of gender in the socialization of high school students and also include gender egalitarianism in sex education. In this context, further study should be done for the improvement of students' communication within the framework of egalitarianism based upon parents' hugs(semi-language). Continued study is especially important in regards to the mother's hug and its enhancement of the students' gender egalitarianism.

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A Case of Esophageal Perforation and Mediastinitis complicated after Foreign Body Ingestion (식도천공 및 종격동염을 초래한 식도이물 1례)

  • 김무명;나기상;김광현;박찬일
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1981.05a
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    • pp.8.5-9
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    • 1981
  • Foreign body in the esophagus is not uncommon in the otolaryngological field and esophageal perforation followed by mediastinitis is one of the most serious complications. Authors had experienced such case developed in 69 year old female patient. This woman swallowed a piece of sharp glass accidentally. Severe pain and swelling around the neck developed after ingestion. Marked subcutaneous emphysema was noted on first examination. By esophagoscopy, longitudinal laceration at right lateral wall of the cervical esophagus was noted and a lot of food debries were removed through this perforation, but foreign body could not be found. On third hospital day, patient complained chest pain and dyspnea. Mediastinal widening was noted on chest P-A. Tracheostomy was performed on next day and neck swelling decreased much. In spite of massive antibiotics, mediastinal abscess was developed and external drainage was performed on 15th hospital day. She was discharged on 38th hospital day with marked improvement and recovered completely on follow-up study. Still, we do not know where the foreign body is located.

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A Case of Tuberculous Pericardial Abscess Mimicking Thymic Carcinoma (악성 흉선종으로 오인된 결핵성 심낭농양 1예)

  • Park, Ji-Young;Park, Seung-Ah;An, Young-Hwan;Jang, Gil-Su;Kim, So-Yeon;An, Jeung-Sun;Hong, Eun-Young;Lim, Soo-Young;Kim, Kun-Il;Seo, Jin-Won;Park, Sung-Hoon
    • Tuberculosis and Respiratory Diseases
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    • v.70 no.4
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    • pp.347-351
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    • 2011
  • We report here an unusual case of pericardial tuberculoma that was misdiagnosed as thymic carcinoma on an imaging study. A 48-year-old woman was referred for evaluation of an anterior mediastinal mass. Computed tomography (CT) scans of the chest displayed cystic masses mimicking thymic carcinoma at the anterior mediastinum. Pericardiotomy and surgical drainage of the cystic masses were done, and pathologic examination of the excised pericardial specimen showed a chronic granulomatous inflammation with necrosis, compatible with tuberculosis. Acid-fast bacilli were also identified in the specimen. After treatment with anti-tuberculosis drugs and steroids, the patient showed clinical improvement. Although tuberculous pericarditis usually presents as pericardial effusion or constrictive pericarditis, it can also present as a pericardial mass mimicking thymic carcinoma on CT. Therefore, we suggest that tuberculous pericardial abscess should be included in the differential diagnosis of a mediastinal mass in Korea, with intermediate tuberculosis prevalence.

Coexistence of Hodgkin's Lymphoma and Tuberculosis in the Same Axillary Lymph Nodes (결핵과 호지킨 림프종이 액와부 림프절에 공존하였던 1예)

  • Ban, Woo-Ho;Kang, Hyeon-Hui;Baeg, Myong-Ki;Kim, Jae-Gyung;Kim, Hyun-Jin;Baek, In-Woon;Kim, Eun-Oh;Ko, Sun-Hye;Lee, Sang-Haak;Moon, Hwa-Sik;Min, Ki-Ouk
    • Tuberculosis and Respiratory Diseases
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    • v.70 no.4
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    • pp.342-346
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    • 2011
  • Herein we report the case of a 71-year-old woman who complained of fatigue and enlarged right axillary lymph nodes for 18 months. At her first visit, her chest X-ray showed diffuse nodular opacities in both lung fields. Initial excisional biopsy of the axillary lymph nodes showed granulomatous lesions and acid fast bacilli were seen on Ziehl-Neelsen staining. However, even after 15 months of anti-tuberculosis (TB) medication, her right axillary lymph nodes were enlarged. We re-performed an excisional biopsy of the nodes, which showed Hodgkin's lymphoma (HL). A retrograde review of the biopsy before anti-tuberculous medication, revealed HL coexisting with TB. HL and TB cause difficulties in differential diagnosis due to similarities in clinical course, imaging procedures and histopathological analysis of the involved tissue. Therefore, it is important to consider the possibility of concurrent HL and TB when patients who undergo treatment for TB or chemotherapy for lymphoma complain of persistent systemic symptoms or enlarged lymph nodes.

Bilioptysis Caused by Bronchobiliary Fistula Secondary to Sclerosing Therapy of Liver Cyst (간낭종 경화 치료 후 발생한 기관지담관루에 의한 담즙성 객담 1예)

  • Lee, Sang-Hoon;Lee, Kyung-Jong;Kim, Song-Yee;Lee, Sang-Kook;Jung, Kyu-Sik;Park, Byung-Hoon;Jung, Ji-Ye;Son, Ji-Young;Yoon, Yoe-Wun;Kang, Young-Ae;Park, Moo-Suk;Kim, Young-Sam;Chang, Joon;Kim, Se-Kyu;Moon, Jin-Wook
    • Tuberculosis and Respiratory Diseases
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    • v.69 no.2
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    • pp.119-123
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    • 2010
  • Bronchobiliary fistula is a rare disorder consisting of an abnormal communication between the bronchial tree and the biliary duct. In Western countries, trauma, postoperative biliary stenosis, and biliary lithiasis are the predominant causative factors of bronchobiliary fistula. Bilioptysis (bile stained sputum) is a pathognomic finding for bronchobiliary fistula. To date, there are just a few reported cases of bronchobiliary fistula after sclerosis of a liver cyst. We describe the case of a 74-year-old woman who developed bronchobiliary fistula after sclerosing therapy of a liver cyst. The diagnosis was confirmed by the presence of bilioptysis and the chest and dynamic liver CT findings. The patient was successfully treated with antibiotics and percutaneous transhepatic catheter drainage.

A Case of Spontaneously Regressed Endobronchial Sarcoma after Obstructive Pneumonia (폐쇄성 폐렴 후 자연 퇴행을 보인 기관지내 육종 1예)

  • Park, Sun Hyo;Jeon, Yong June;Kwon, Kun Young;Han, Seung Beom
    • Tuberculosis and Respiratory Diseases
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    • v.63 no.1
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    • pp.94-99
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    • 2007
  • The spontaneous regression (SR) of cancer is defined as the complete disappearance of a malignant disease without adequate treatment. SR is a very rare biological event, particularly in a pulmonary sarcoma. We report the first documented case of an endobronchial sarcoma that regressed spontaneously in Korea. We encountered a rare case of a 72-year-old woman with an undiagnosed intrapelvic cystic mass, who presented with a smooth surfaced endobronchial tumor obstructing the orifice of the right lower lobe bronchus on a bronchoscopic examination. She had a prior history cervical cancer and adenocarcinoma in the right middle lobe lateral segment of her lung for which she had undergone radiation therapy. The tumor was diagnosed as an endobronchial sarcoma by the histopathology findings and immunohistochemistry. It was unclear if the tumor was a primary sarcoma of the lung or a metastatic lesion of an intrapelvic cystic mass because she refused a diagnostic exploratory laparotomy. Two months later, obstructive pneumonia of the right lower lobe with parapneumonic effusion developed with fever above 38.5degrees C for 10 days. After recovering from pneumonia, she was followed up regularly in the outpatient clinic without any specific treatment. One year later after treating the obstructive pneumonia, the follow-up bronchoscopy revealed complete SR of endobronchial sarcoma. It is believed that the obstructive pneumonia accompanied by fever above 38.5degrees C for 10 days might have played a role in this SR.

Prenatal Diagnosis of a Satellited Chromosome 8p Results from a de novo Cryptic Translocation between Chromosomes 8 and 22 (산전 진단에서 관찰된 8번과 22번 염색체 사이의 미세 전좌에 의한 8번 염색체 단완 위성체)

  • Oh, Ah-Rum;Lee, Bom-Yee;Choi, Ene-Yuong;Ryu, Hyun-Mee;Lee, Seung-Jae;Jung, Ji-Ye;Park, So-Yeon
    • Journal of Genetic Medicine
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    • v.8 no.2
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    • pp.135-138
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    • 2011
  • The authors of the present study report the prenatal detection of a chromosomal abnormality with additional satellites on the distal short arm of chromosome 8. A 35-year-old woman was referred for amniocentesis because of her advanced maternal age and positive result for maternal serum screening test. Cytogenetic analysis of cultured amniocytes showed a satellite 8p chromosome. The satellite 8p chromosome was positive for nucleolus organizer region (NOR) staining. The parents' karyotypes were normal. Fluorescence in situ hybridization (FISH) study for metaphases of fetal amniocytes revealed a cryptic translocation of chromosomes 8p and 22p. The fetal karyotype was described as 46,XY,8ps.ish t(8;22)(p23.3;p11.2) (D8S504-;D8S504+)dn. The parents decided to continue the pregnancy and a phenotypically normal boy was born at 38 weeks of gestation. In case of de novo terminal NORs detected prenatally, more accurate cytogenetic and molecular analysis should be performed in order to rule out cryptic chromosomal rearrangement among other chromosomes.