Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Primary Choriocarcinoma of the Lung

원발성 폐 융모막암종 1예

  • Cho, Young-Jae (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Lung Institute, Seoul National University College of Medicine) ;
  • Lee, Sei Won (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Lung Institute, Seoul National University College of Medicine) ;
  • Lee, Sang Min (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Lung Institute, Seoul National University College of Medicine) ;
  • Yim, Jae-Joon (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Lung Institute, Seoul National University College of Medicine) ;
  • Yoo, Chul-Gyu (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Lung Institute, Seoul National University College of Medicine) ;
  • Han, Sung Koo (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Lung Institute, Seoul National University College of Medicine) ;
  • Shim, Young-Soo (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Lung Institute, Seoul National University College of Medicine) ;
  • Kim, Young Whan (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Lung Institute, Seoul National University College of Medicine)
  • 조영재 (서울대학교 의과대학 내과학교실, 폐 연구소) ;
  • 이세원 (서울대학교 의과대학 내과학교실, 폐 연구소) ;
  • 이상민 (서울대학교 의과대학 내과학교실, 폐 연구소) ;
  • 임재준 (서울대학교 의과대학 내과학교실, 폐 연구소) ;
  • 유철규 (서울대학교 의과대학 내과학교실, 폐 연구소) ;
  • 한성구 (서울대학교 의과대학 내과학교실, 폐 연구소) ;
  • 심영수 (서울대학교 의과대학 내과학교실, 폐 연구소) ;
  • 김영환 (서울대학교 의과대학 내과학교실, 폐 연구소)
  • Received : 2006.08.07
  • Accepted : 2006.10.18
  • Published : 2006.12.30
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Abstract

A primary choriocarcinoma of the lung is extremely rare, and difficult to distinguish from a metastatic choriocarcinoma considering that the lung is also one of the most frequent sites of metastasis. We report a 28-year-old woman patient who was initially misdiagnosed with an ectopic pregnancy and was operated on under the impression of an unidentified malignancy of the lung, which was finally proven to be a choriocarcinoma of the lung. A pelvic examination by a gynecologist, pelvic magnetic resonance imaging and whole body fluorodeoxyglucose positron emission tomography-computed tomography was performed in order to rule out a metastatic choriocarcinoma of the lung. After a curative operation, her serum ${\beta}$-human chorionic gonadotropin (HCG) level, which was highly elevated in the initial evaluation, had decreased dramatically to the normal range. She is currently being followed up regularly without any evidence of recurrence or elevation of her ${\beta}$-HCG level.

저자들은 뚜렷한 종양성 병변이 방사선학적으로는 물론 전신 PET에서도 유일하게 폐에서만 발견이 되었고, 산부인과적 검진 및 골반 MRI 검사에서도 원발성 종양을 의심할만한 병변이 발견되지 않았으며, 병리학적으로 면역조직화학염색을 통해 ${\beta}$-HCG에 양성인 원발성 폐 융모막암종의 증례를 경험하였기에 이 환자의 임상적 소견과 경과를 문헌 고찰과 함께 보고하는 바이다.

Keywords

References

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