• 한방재활의학과학회지
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• 제32권4호
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• pp.47-60
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• 2022

Objectives The purpose of this study is to identify the latest research trends regarding the nonsurgical treatment of rib fractures and suggest the direction for future research. Methods We searched for papers published from January 1, 2015 to July 1, 2022 in PubMed and the China National Knowledge Infrastructure (CNKI) based on keywords 'rib fracture'. 'Korean medicine', 'oriental medicine', 'TCM', 'moxibustion', 'acupunture', 'cupping', 'electroacupuncture', 'pharmacopuncture', 'fire needling'. Results A total of 79 studies were searched at first research. Then the studies were screening according to criteria and Finally 20 studies were selected. The oriental medical interventions analyzed in this study were fumigation method, herbal medicine, external application, acupuncture, ointment, herb fomentation, Tending Diancibo Pu far-infrared therapy. Conclusions Various oriental medical interventions such as herbal medicine, acupuncture, fumigation, herb fomentation, ointment, and physical therapy are being studied abroad for the treatment of rib fractures. It is considered that additional research related to the nonsurgical treatment for rib fractures is needed in the future in korea.

• Journal of Yeungnam Medical Science
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• 제16권2호
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• pp.347-356
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• 1999

복막 투석은 혈액 투석 및 신 이식과 함께 말기 신 질환의 중요한 치료 방법의 하나로 성공적인 복막 투석을 위해서는 복막 투석에 따른 여러 합병증을 줄이는 것이 필수적이다. 그러나 도관 출구 감염이나 복막염 등 투석 관련 감염은 여전히 도관 제거로 인한 복막 투석의 중단을 유발하는 중요한 원인이 되고 있다. 영남대학 의과대학 부속병원에서 1993년 10월부터 1999년 2월까지 복막 투석을 시행 후 추적 가능한 139명의 환자를 대상으로 도관 출구 감염과 복막염의 발생 빈도 및 원인 균주, 도관 제거의 빈도 및 원인 균주, 도관 전환술의 성적, 그리고 mupirocin ointment 사용 전과 사용 후의 도관 출구 감염의 빈도 차이 등을 후향 분석하였다. 복막 투석을 시행한 총 환자-투석기간은 2,401개월이었고 도관 출구 감염은 36명의 환자에서 105례 발생하여 발생 빈도는 1/22.8 환자-개월이었고 복막염은 67명의 환자에서 112례 발생하여 그 빈도는 1/21.4 환자-개윌로 나타났다. 대다수 출구 감염의 경우 일반적인 투약에 잘 반응하였으나 치료에 불응하여 도관 전환술을 시행한 7명 중 5명은 메티실린 저항성 포도상 구균(Methicillin Resistant, Staphylococcus aureus, MRSA), 2명은 Pseudomonas aeruginosa에 의한 감염이었다. revision후 3명에서 감염이 재발하였으나 한 명은 항생제에 바로 치유되었고 또 한 명은 second revision으로 치료하였으며 나머지 한 명은 MRSA에 의한 반복 감염이 지속되어 결국 도관 제거와 동시에 도관 재삽입을 시행하였다. 재발에 대한 치료 후 평균 추적기간 14.0개월 동안 더 이상의 출구 감염은 없었다. 1998년 10월부터 1999년 2월까지 mupirocin을 국소 도포 한 34명의 환자를 살펴보면, pre-mupirocin 기간의 총 투석기간은 687개월이었고 그 기간동안 도관 출구 감염이 54례 발생하여 발생 빈도는 1/12.7 환자-개월로 나타났으나 mupirocin 기간의 경우 총 투석기간 136개월 동안 4례 발생하여 그 빈도가 1/34.0 환자-개월로 유의하게(P<0.01) 감소하였다. 도관 출구 감염의 72.2%가 SA에 의한 것으로 조기에 적절한 항생제 치료를 함으로써 대부분 완치되었고 일부 약제에 잘 반응하지 않고 반복 감염되어 도관 탈락의 위험이 있는 경우에도 도관 전환술을 통하여 비교적 안전하고 효과적으로 난치성 출구 감염을 치유할 수 있었다. 그리고 도관 출구 부위에 mupirocin을 간헐적으로 국소 도포 함으로써 포도상 구균(Staphylococcus aureus)에 의한 출구 감염을 예방할 수 있었다. 그러나 이러한 도관 전환술과 mupirocin의 장기적인 효과 및 부작용에 대해서는 보다 많은 환자군을 대상으로 하는 전향적 연구가 있어야 할 것으로 생각된다.

• Archives of Pharmacal Research
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• 제11권3호
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• pp.185-196
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• 1988

The inflence of hydrophilic vehicles on percutaneous absorption rate of griseofulvin was studied using intact skin of full thickness of hairless rat. The in vitro absorption rates were used as the characteristics for deciding the optimum formula of ointment vehicles. The optimum formula of vehicle compositions for maximum absorption rate was obtained from the polynomial regression equation and the two graphical techniques, contour graph and partial derivative graph. It was composed of sodium lauryl sulfate (1.65 W /W%), white petrolatum (16.5 W /W%), propylene glycol (12.0 W /W%), and stearyl alcohol (19.6W /W%). The experimental value obtained from the optimum formula and the prediction value were 33.99 and 33.87 ${\mu}g/\sqrt{min}$, respectively. From these results, it was believed that optimum formula for semisolid dosage forms could be obtained from the application of the optimization technique used in this study.

• 사상체질의학회지
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• 제15권2호
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• pp.111-116
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• 2003

Drug Eruption refers to an adverse effect which is unintentionally given rise to by dosage, injection, inhalation, suppository and ointment, etc. Hereby this report is about a remedial value of Gwaghyangjungkisan which was prescribed for a 78 year-old male featuring Soeumin who had suffered from papular eruption after taking a medicine composed of extract of gingko leaves.

• Biomolecules & Therapeutics
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• 제1권2호
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• pp.280-283
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• 1993

Single subcutaneous injection to SD rats of both sexes was performed to investigate the acute toxicity of new skin allergy-remedy ointment, Banaron. Banaron is composed of lidocaine hydrochloride, chloro-pheniramine maleate, prednisolone acetate, chlorohexidine hydrochloride, methyl salicylate, 1-menthol and d-camphor. The results were as fellows. $LD_{50}$, /TEX> values of Banaron were 8373.6 mg/kg for male and 8260.1 mg/kg for females. Death occurred within 24 hours after administration at doses up to 6600 mg/kg. The main cause of deaths seemed to be respiratory disturbance. General symptoms decreased of activity and respiratory rate, salivation, tremor and loss of consciousness which were commonly observed by some survived animals and all dead animals. No significant gross findings of internal organs and body weight changes in treatment groups in comparison with these of control group were observed at the maximum dose levels in Banaron.

• 한방안이비인후피부과학회지
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• 제18권2호
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• pp.104-108
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• 2005

Drug eruption refers to an adverse effect which is unintentionally given rise to by dosage, injection, inhalation, suppository and ointment, etc. Maculopapular, urticarial, morbilliform, papulosquamous, pustular, and bullous morphologies may be encountered. Adverse drug reactions also can cause pruritus or dysesthesia unaccompanied by rash. We treated a patient suffered from maculopapular rash and pruritus with acupuncture, herb medication and wet dressing. After treatment we observed the improvement. Based on this study, it is considered that oriental medical treatment can be applied to the management of drug eruption.

• Advances in pediatric surgery
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• 제15권2호
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• pp.166-172
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• 2009

Labial adhesion in prepubertal girls is a common gynecologic problems. The labia minora are fused by thin transparent or thick fibrous membrane in the midline from the clitoris to posterior fourchet. The prevalence of labial adhesion may be even greater because many children with labial fusions are asymptomatic and these cases remain unreported. They are often unrecognized by physician and parents because most of symptomatic children complained urinary symptoms. The authors experienced 2 cases of labial adhesion in girls; one asymptomatic partial fusion and the other symptomatic complete fusion. These lesions were treated successfully by mechanical separation of labial adhesion and petroleum ointment (Vaseline) application without recurrence in follow-ups.

• 대한약침학회지
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• 제10권3호
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• pp.127-135
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• 2007

Objectives This study observed the efficacy of bee venom pharmacopuncture on the treatment of Molluscum Contagiosum commonly manifesting in children. Methods 104 patients admitted for Molluscum Contagiosum at Love Blossoming Oriental medicine clinic from August 2005 to August 2006 were administered with Bee Venom Pharmacopuncture and measured and analyzed changes in symptoms. Results 1. Regardless of age or duration of Molluscum Contagiosum, all 104 patients showed improvement. 2. Recurrence of Molluscum Contagiosum was not noticeable when treated with Bee Venom Pharmacopuncture, and the duration of treatment was significantly shorter than treating with conventional allopathic ointment. 3. Regardless of size or location of Molluscum Contagiosum, most cases improved with one or two treatments. Conclusion Based on above findings, we can deduce Bee Venom Pharmacopuncture has superior anti-viral effects on the pox virus of molluscum contagiosum (MCV1,2).

• 대한한의학원전학회지
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• 제22권2호
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• pp.107-126
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• 2009

King Seonjo, the second son of King Jeongjo, is the twenty-third King of the Joseon Dynasty. He suffered mainly from spleen-stomach weakness syndrome[脾胃虛弱], neurasthenic neurosis and abscess according to the Annals of the Joseon Dynasty[朝鮮王朝實錄]. He experienced chicken pox at the age of twelve, measles at thirteen, smallpox at sixteen. In his twenties he was ill with chronic breakdown due to the spleen-stomach weakness[脾胃虛弱], accompanied by neurasthenia. Abscess occurred during his twenties and the septicemia induced by abscess worsening led him to death. Most treatments were herb-extract medication taken orally, and to some extent ointment care was applied as a cure for abscess.

• 대한약침학회지
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• 제11권2호
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• pp.111-116
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• 2008

Objectives This study obserbed the efficiency of Sweet Bee Venom pharmacopuncture on the treatment of 70 Molluscum Contagiosum cases. Methods 70 patients admitted for Molluscum at Love Blossoming Oriental medicine clinic from February 2007 to October 2007 were administered with Sweet Bee Venom Pharmacopuncture and measured an analyzed changes in symptoms. Results 1. Regardless of age or duration of Molluscum Contagiosum, all 70 patients showed improvement. 2. Recurrence of Molluscum Contagiosum was not noticeable when treated with Sweet Bee Venom Pharmacopuncture, and the duration of treatment was significantly shorter than treation with conventional allopathic ointment. Conclusion Based on above findings, we can deduce Sweet Bee Venom Pharmacopuncture has superior anti-viral effects on th pox virus of Molluscum Contagiosum.