• Title/Summary/Keyword: oil release

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Use of floating alginate beads for stomach drug delivery (부유특성을 갖는 알지네이트 비드를 이용한 위에서의 약물방출)

  • Song, Won-Hyun;Lee, Ki-Young
    • 한국생물공학회:학술대회논문집
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    • 2002.04a
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    • pp.139-144
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    • 2002
  • Two types of alginate gel beads capable of floating in the gastric cavity were prepared. The first, alginate gell bead containing olive oil(Al-Oil), is a hydrogel bead and its buoyancy is attributable to olive oil held in the alginate gel matrix. The model drug, metronidazole(MZ), contained in Al-Oil was released gradually into artificial gastric fluid. The profiles of MZ release from Al-Oil shown initial burst and after 90 min they were about 100%. The second, alginate gel bead containing curdlan microsphere(Al-C), is a gel bead with curdlan-MZ microsphere in the matrix. To sustained release rate of drug, alginate bead were prepared curdlan microsphere containing MZ. Results demonstrated that sustained delivery of MZ over 2h can be easily achieved while the bead remained float. The release properties of prepared alginate beads are applicable not only for sustained release of drugs but also for targeting the gastric mucosa.

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Evaluation of the Characteristics of Asphalt Release Agents (국내 아스팔트 릴리스 에이전트의 특성 평가)

  • Kim, Boo-Il
    • International Journal of Highway Engineering
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    • v.9 no.2 s.32
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    • pp.13-25
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    • 2007
  • Viscosity, adhesion and cohesion of asphalt binder are very important characteristics in asphalt pavement. However, these characteristics can cause some problems such as inaccurate amount of asphalt mixture, reduction of asphalt content and loss of workability during asphalt pavement construction. Asphalt release agent has been used to solve these problems. Diesel oil and vegetable oil are generally used as an asphalt release agent in Korea. However, these agents have been criticized from environmental and binder integrity reasons. Therefore, this study evaluated the characteristics of asphalt release agents including diesel oil, vegetable oil and two emulsion type oils. From the study, it was found that the diesel oil resolved the binder within ten minutes and vegetable oil stripped the binder from mixture within one hour after contacting with asphalt mixture. And also, from the test for estimating the application cycle of asphalt release agent, it appears that diesel oil and vegetable oil should be applied to construction equipments every time in their uses. However, diesel oil and vegetable oil showed a good performance as a lubricant for detaching the asphalt mixtures from the truck bed.

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Optimization of Emulsification and Spray Drying Process for the Microencapsulation of Flavor Compounds (향기성분 미세캡슐화를 위한 유화 및 분무건조 공정 최적화)

  • Cho, Young-Hee;Shin, Dong-Suck;Park, Ji-Yong
    • Korean Journal of Food Science and Technology
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    • v.32 no.1
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    • pp.132-139
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    • 2000
  • This study was conducted to optimize the emulsion process and the spray drying process for the microencapsulation of flavor compounds. Using the wall system selected, emulsion process for microencapsulation was optimized on the change of the pressure of piston-type homogenizer. Emulsification pressure of 34.5 MPa was found to be the most suitable for preparing flavor emulsion. Effects of drying temperature and atomizer speed of the spray drier on total oil, surface oil, and flavor release of the flavor powder were investigated using response surface methodology. The optimum spray drying conditions for minimal surface oil and flavor release and maximum total oil were $170{\circ}C$ inlet temperature and 15,000 rpm atomizer speed. The spray-dried powder processed with the highest drying temperature showed spherically-shaped particles with smooth surface.

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Preparation and Characterization of Poly(lactide-co-glycolide) Micro-spheres for the Sustained Release of AZT

  • Gilson Khang;Lee, Jin-Ho;Lee, Jin-Whan;Cho, Jin-Cheol;Lee, Hai-Bang
    • Macromolecular Research
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    • v.8 no.2
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    • pp.80-88
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    • 2000
  • Biodegradable microspheres were prepared with poly(L-lactide-co-glycolide) (PLGA, 75 : 25 by mole ratio) by an oil/oil solvent evaporation method for the sustained release of anti-AIDS virus agent, AZT The microspheres of relatively narrow size distribution (7.6$\pm$ 3.8 ㎛) were obtained by controlling the fabrication conditions. The shape of microspheres prepared was smooth and spherical. The efficiency of AZT loading into the PLGA microsphere was over 93% compared to that below 15% for microspheres by a conventional water/oil/water method. The effects of Preparation conditions on the morphology and in vitro AZT release pattern were investigated. in vitro release studies showed that different release pattern and release rates could be achieved by simply modifying factors in the fabrication conditions such as the type and amount of surfactant, initial amount of loaded drug, the temperature of solvent evaporation, and so on. PLCA microspheres prepared by 5% of initial drug loading, 1.0% (w/w) of surfactant concentration, and 25$\^{C}$ of solvent evaporation temperature were free from initial burst effect and a near-zero order sustained release was observed. Possible mechanisms of the near-zero order sustained release for our system have been proposed.

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A Study on the Engine Performance and Combustion Characteristics of Fish Oil in a Diesel Engine (디젤기관에서의 어유의 연소특성과 기관성능에 관한 연구)

  • 서정주;왕우경;안수길
    • Transactions of the Korean Society of Automotive Engineers
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    • v.2 no.3
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    • pp.85-93
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    • 1994
  • The engine performance and combustion characteristics of diesel oil and fish oil blended with diesel oils were investigated at various blending rate of fish oil in a diesel engine. The maximum pressure showed no significant difference among test fuels at low load, but it was higher as the blending rate of fish oil increases at high load. Increasing the blending rate of fish oil, the rate of heat release and burned fraction were higher than those of diesel oil. The ignition delay became longer than that of diesel oil as the blending rate of fish oil increases, and its differences were larger at different loads. The combustion duration and density of smoke were shorter and lower as the blending rate of fish oil increases. The rate of fuel consumption showed no significant difference between diesel oil and fish blended with diesel oils.

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Essential oil impregnation into graphene sponges with electric desorption control

  • Mendez, Jose Antonio Cabello;Bueno, Jose de Jesus Perez;Valencia, Jorge Ivan Mendoza;Soto, Jonathan Soto;Lopez, Maria Luisa Mendoza;Guerrero, Mizraim Uriel Flores
    • Advances in nano research
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    • v.12 no.6
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    • pp.629-638
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    • 2022
  • This work shows the impregnation of scents using a graphene sponge (GS). This was functionalized by the modified Hummers method, pursuing to add different functional groups. It is proposed to achieve the release and seek to control it through electrical potential applied to the graphene sponge with essential oils. The graphene sponge was functionalized and steeped with two kinds of oil. The electrochemical study demonstrates the variation in the electrochemical behaviour of the functionalized graphene sponge without and impregnated with oil. The release of the oil and its aromatic scents was carried out by applying an electrical potential of 30 V, with a release rate of 1.86 mg/min. The heating of the sample that causes the release of oil, associated with the electrical resistance of the system, reaches temperatures of about 150℃. The essential oils, graphene sponge, surfactant, graphene sponge with essential oils, graphene sponge recuperated after applying electric potential, graphene sponge recovered by temperature and dipropylene glycol (DPG) were characterized using Fourier transformed infrared spectroscopy (FTIR), digital microscopy, and x-ray photoelectron spectroscopy (XPS).

Effect of the Pan Oil Type on the Releasing Power, Changes of Peroxide and Acid alue of the Oil (이형유 종류에 따른 Cake 제품의 이탈성, 이형유의 과산화물가 및 산가의 변화)

  • 이정훈;조남지
    • The Korean Journal of Food And Nutrition
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    • v.11 no.2
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    • pp.137-142
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    • 1998
  • This study aims to examine appropriate kinds of pan oil to release a cake from the pan coated with polyether sulphone and to prove the change of acid value and peroxide value during the process of baking. The major factor effecting the rate of release of the cakes from the pan was properties of the oils rather than the additives. The releasing rate appeared higher as the iodine value was lower. The highest releasing rate was found in the sample, which was made of coconut oil plus 2% of wax, 2% of lecithin. The changes of acid value of the pan oil between the beginning and after baking was little different. In contrast, Peroxide value showed a great change after baking.

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Encapsulation of Flavors by Molecular Inclusion Using $\beta$-Cyclodextrin: Comparison with Spray-drying Process Using Carbohydrate-based Wall Materials

  • Cho, Young-Hee;Park, Ji-Yong
    • Food Science and Biotechnology
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    • v.18 no.1
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    • pp.185-189
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    • 2009
  • Microencapsulation of flavor was carried out by molecular inclusion process using $\beta$-cyclodextrin (${\beta}CD$). ${\beta}CD$-flavor complex was prepared at various flavor-to-${\beta}CD$ ratios (1:6-1:12) to determine the effect of ${\beta}CD$ concentration on the inclusion efficiency. Maximum total oil retention and minimal surface oil content were obtained at flavors to ${\beta}CD$ ratio of 1:10. The physical properties and controlled release pattern of flavors from ${\beta}CD$-flavor complex were measured and compared with spray-dried microcapsules prepared using carbohydrate wall system. ${\beta}CD$-flavor complex showed higher total oil retention and surface oil contents, smaller mean particle size, lower moisture uptake, and higher oxidation stability than spray-dried microcapsule. Oxidative stability of flavor was correlated with hygroscopicity of wall materials. The controlled release mechanism was highly affected by temperature and characteristics of wall materials.

Influence of Surface Treatment of SiO$_2$ and Stirring Rate on Fragrant Oil Release Behavior of Poly($\varepsilon$-caprolactone) Microcapsules (실리카의 표면 처리와 교반 속도가 폴리카프로락톤 마이크로캡슐의 향유 방출 거동에 미치는 영향)

  • 박수진;양영준;이재락;서동학
    • Polymer(Korea)
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    • v.27 no.5
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    • pp.464-469
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    • 2003
  • In this work, the fragrant oil release behavior of poly($\varepsilon$-caprolactone) (PCL) microcapsules containing SiO$_2$ was investigated. The SiO$_2$ was chemically treated in 10, 20, and 30 wt% hydrochloric acid and sodium hydroxide. The acid and base values were determined by Boehm's titration technique and $N_2$/77 K adsorption isotherm characteristics, the specific surface area and total pore volume were studied by BET. The PCL microcapsules containing SiO$_2$ and fragrant oil were prepared by oil-in-water (o/w) emulsion solvent evaporation method. The shape and surface of PCL microcapsules were observed using image analyzer and scanning electron microscope (SEM). The fragrant oil release behavior of PCL microcapsules was characterized using UV/vis. spectra. The average diameters of PCL microcapsules were decreased from 35 to 21 $\mu$m with increasing stirring rate. It was found that in the case of acidic treatment the fragrant oil adsorption capacity and release rate were increased due to the increase of specific surface area and acid value. In the case of basic treatment, the fragrant oil adsorption capacity and release rate were decreased due to the decrease of sp ecific surface area and the increase of acid-base interactions between SiO$_2$-NaOH and fragrant oil with increasing base value of SiO$_2$.

A Study on the Performance Characteristics According to the Compression Ratio of Spark Ignition Engine Fuelled with Coal Oil (Coal Oil을 사용한 스파크 점화기관의 압축비 변화에 따른 엔진 성능에 관한 연구)

  • HAN, SUNG BIN;CHUNG, YON JONG
    • Transactions of the Korean hydrogen and new energy society
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    • v.28 no.2
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    • pp.225-230
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    • 2017
  • Coal oil is widely used as a home heating fuel for portable and installed coal oil heaters. Today, Coal oil is widely used as fuel for jet engines and some rocket engines in several grades. This paper describes the performance characteristics according to the compression ratio of spark ignition engine fuelled with coal oil. As a result, the following knowledge is obtained: As the compression ratio is decreased, there is an increase in torque, indicated mean effective pressure (IMEP), heat release rate, and brake thermal efficiency. Higher compression ratio of the engine decreases the ignition delay period, combustion period, and cooling loss.