• 제목/요약/키워드: off-target

검색결과 435건 처리시간 0.024초

HYBRID ON-OFF CONTROLS FOR AN HIV MODEL BASED ON A LINEAR CONTROL PROBLEM

  • Jang, Tae Soo;Kim, Jungeun;Kwon, Hee-Dae;Lee, Jeehyun
    • 대한수학회지
    • /
    • 제52권3호
    • /
    • pp.469-487
    • /
    • 2015
  • We consider a model of HIV infection with various compartments, including target cells, infected cells, viral loads and immune effector cells, to describe HIV type 1 infection. We show that the proposed model has one uninfected steady state and several infected steady states and investigate their local stability by using a Jacobian matrix method. We obtain equations for adjoint variables and characterize an optimal control by applying Pontryagin's Maximum Principle in a linear control problem. In addition, we apply techniques and ideas from linear optimal control theory in conjunction with a direct search approach to derive on-off HIV therapy strategies. The results of numerical simulations indicate that hybrid on-off therapy protocols can move the model system to a "healthy" steady state in which the immune response is dominant in controlling HIV after the discontinuation of the therapy.

온라인 2단계 방법을 이용한 회분식 PS 중합반응기의 온도제어 (Temperature control of a batch PS polymerization reactor using on-line two-step method)

  • 이병모;노형준;이현구
    • 제어로봇시스템학회:학술대회논문집
    • /
    • 제어로봇시스템학회 1997년도 한국자동제어학술회의논문집; 한국전력공사 서울연수원; 17-18 Oct. 1997
    • /
    • pp.305-308
    • /
    • 1997
  • The on-line calculation method is developed to obtain the temperature trajectory that brings the reactants to the desired state in batch styrene polymerization reactor. The temperature trajectory is obtained by applying the moments of the polymer concentration to the 2-step calculation method. The computer simulation is also carried out to verify the superiority of the on-line method to the off-line one. When a temperature disturbance of constant size is introduced, the off-line results shows considerable deviation from the target degree of polymerization. The on-line strategy set up a new trajectory to reach the desired state by using the current state of the reactor. Therefore, the on-line strategy deals with the changes of the system more adequately than the off-line strategy.

  • PDF

An Industrial Manipulator for Shipbuilding;Off-Line Programming and Open Architecture

  • Lee, Ji-Hyoung;Hong, Kyung-Tae;Oh, Seung-Min;Hong, Keum-Shik
    • 제어로봇시스템학회:학술대회논문집
    • /
    • 제어로봇시스템학회 2005년도 ICCAS
    • /
    • pp.397-402
    • /
    • 2005
  • In this paper, to improve the efficiency of welding and user convenience in the shipbuilding industry, a PC-based off-line programming (OLP) technique and the development of a robot transfer unit are presented. The developed OLP system is capable of not only robot motion simulations but also automatic generations of a series of robot programs. The strength of the developed OLP system lies in its flexibility in handling the changes of the welding robot's target objects. Moreover, for a precise transfer of the robot to a desired location, an auxiliary mobile platform named a robot-origin-transfer-unit (ROTU) was developed. To enhance the cornering capability of the platform in a narrow area, the developed ROTU is equipped with 2 steering wheels and 1 driving wheel. Both the OLP and the ROTU were field-tested and their performances were proven successful.

  • PDF

HEMT 소자 공정 연구 (Part 1. 금속박막 형성을 위한 Lift-off 공정연구) (A Study on HEMT Device Process (Part I. Lift-off Process for the Metallization))

  • 이종람;박성호;김진섭;마동성
    • 대한전자공학회논문지
    • /
    • 제26권10호
    • /
    • pp.1535-1544
    • /
    • 1989
  • The overhang structure of photoresist in optical lithography was studied for the metallization of GaAs-related devices throughout lift-off method. Optical contact aligner with a dose of 8.5 m J/cm\ulcornerand with a wavelength of 300mm was used for ultraviolet exposure of single layer of S1400-27 photoresist. The overhang thickness shows a linear relationship with the soaking time in monochlorobenzene, which its magnitude becomes high at elevated softbake temperature. Such process conditions as a low softbake temperature, a long monochlorohbenzene soaking time and a little exposed energy make the development rate of photoresist lower. The optimum process conditions to obtain a target line-width, which include an appropriate overhang structure such as complete separation between the sidewall of photoresist pattern and the deposited metal edge, are determined as the softbake temperature of 64-74\ulcornerC, the monochlorobenzene soaking time of 10-15min, the ultraviolet exposure time of 70-100sec and the development time of 50-80sec.

  • PDF

Off-axis Sputtering 방법으로 제조한 $Bi_2Sr_2Ca_2Cu_3O_x$ 박막의 초전도상 생성에 관한 연구 (Study on the Formation of Superconducting Phases of $Bi_2Sr_2Ca_2Cu_3O_x$ Thin Films Prepared by Off-axis Sputtering)

  • 심창훈;양우석;제정호
    • 한국세라믹학회지
    • /
    • 제31권7호
    • /
    • pp.715-722
    • /
    • 1994
  • Off-axis supttering using shielder was used to efficiently prevent negative oxygen ions from resputtering deposited films. In this method, the substrate was located vertically to the target and shielded by the semicircled steel plate. By using this method, the resputtering could be reduced, and 2223 high-Tc phase could be formed at the lower substrate temperature and in the broader temperature region. As increasing the substrate temperature, 2212, 2223, 2212 superconducting phases were formed by turns. 2223 phase was formed above 2$\times$10-2 torr, and 2212 phase was formed above 4$\times$10-2 torr.

  • PDF

Off-Line Programming in the Shipbuilding Industry: Open Architecture and Semi-Automatic Approach

  • Lee Ji-Hyoung;Kim Chang-Sei;Hong Keum-Shik
    • International Journal of Control, Automation, and Systems
    • /
    • 제3권1호
    • /
    • pp.32-42
    • /
    • 2005
  • In this paper, to improve the efficiency of welding and user convenience in the shipbuilding industry, a PC-based off-line programming (OLP) technique and the development of a robot transfer unit are presented. The developed OLP system is capable of not only robot motion simulations but also automatic generations of a series of robot programs. The strength of the developed OLP system lies in its flexibility in handling the changes of the welding robot's target objects. Moreover, for a precise transfer of the robot to a desired location, an auxiliary mobile platform named a robot-origin-transfer-unit (ROTU) was developed. To enhance the cornering capability of the platform in a narrow area, the developed ROTU is equipped with 2 steering wheels and 1 driving wheel. Both the OLP and the ROTU were field­tested and their performances were proven successful.

The Characteristics of Accepted Work-related Injuries and Diseases Claims in the Australian Coal Mining Industry

  • Chong, Heng T.;Collie, Alex
    • Safety and Health at Work
    • /
    • 제13권2호
    • /
    • pp.135-140
    • /
    • 2022
  • Background: Coal mining is a hazardous industry. The purpose of the study is to identify the nature of occupational injuries and diseases among coal miners and to determine the factors that affect the rate of injury and duration of time loss from work. Methods: A retrospective cohort study was conducted using accepted workers' compensation claims data of 30,390 Australian coal miners between July 2003 and June 2017. Results: Musculoskeletal and fracture conditions accounted for approximately 60% of claims in all occupational groups. Cox regression analysis showed that older age and female gender were significant predictors of longer time off work. Injury types and occupations were associated with work time loss: mental health conditions, and machine operators and drivers had significantly longer durations of time off work. Conclusion: Future research can further address how these factors led to longer time off work so that coal industry regulators, employers, and healthcare providers can target interventions more effectively to these at-risk workers.

양상태-단상태 변환 기반 잠수함 양상태 표적강도 해석 (Submarine bistatic target strength analysis based on bistatic-to-monostatic conversion)

  • 김국현;박성주;이근화;조대승
    • 한국음향학회지
    • /
    • 제43권1호
    • /
    • pp.138-144
    • /
    • 2024
  • 본 논문에서는 잠수함 양상태 표적강도 해석을 위한 양상태-단상태 변환 기법을 제안하였다. 이 기법은 송신 음원이 수중 표적면에 의해 산란된 후 수신자에 도달하는 음파 전달 경로 길이를 산정하고, 이에 상응하는 가상 산란면을 생성함으로써, 수중 표적의 표적강도 문제를 양상태에서 단상태로 변환하는 방법이다. 변환된 단상태 표적강도 문제는 기 정립된 단상태 표적강도 수치 해석 기법을 활용하여 양상태 표적강도를 평가한다. 표적강도 표준모델로 활용되고 있는 BeTTSi에 대한 양상태 표적강도 해석을 수행하였으며, 그 결과는 경계 요소법과 키르히호프 근사에 의한 해석 결과와 비교하여 제안된 해석 기법의 신뢰성과 잠수함 표적강도 평가 도구로서의 실무 활용성을 확인하였다.

안구 운동의 생리 (Physiology of Eye Movements)

  • 김지수
    • Annals of Clinical Neurophysiology
    • /
    • 제1권2호
    • /
    • pp.173-181
    • /
    • 1999
  • Eye movements serve vision by placing the image of an object on the fovea of each retina, and by preventing slippage of images on the retina. The brain employs two modes of ocular motor control, fast eye movements (saccades) and smooth eye movements. Saccades bring the fovea to a target, and smooth eye movements prevent retinal image slip. Smooth eye movements comprise smooth pursuit, the optokinetic reflex, the vestibulo-ocular reflex (VOR), vergence, and fixation. Saccades achieve rapid refixation of targets that fall on the extrafoveal retina by moving the eyes at peak velocities that can exceed $700^{\circ}/s$. Various brain lesions can affect saccadic latency, velocity, or accuracy. Smooth pursuit maintains fixation of a slowly moving target. The pursuit system responds to slippage of an image near the fovea in order to accelerate the eyes to a velocity that matches that of the target. When smooth eye movements velocity fails to match target velocity, catch-up saccades are used to compensate for limited smooth pursuit velocities. The VOR subserves vision by generating conjugate eye movements that are equal and opposite to head movements. If the VOR gain (the ratio of eye velocity to head velocity) is too high or too low, the target image is off the fovea, and head motion causes oscillopsia, an illusory to-and-fro movement of the environment.

  • PDF

자율주행 차량의 다 차선 환경 내 차량 추종 경로 계획 (Car-following Motion Planning for Autonomous Vehicles in Multi-lane Environments)

  • 서장필;이경수
    • 자동차안전학회지
    • /
    • 제11권3호
    • /
    • pp.30-36
    • /
    • 2019
  • This paper suggests a car-following algorithm for urban environment, with multiple target candidates. Until now, advanced driver assistant systems (ADASs) and self-driving technologies have been researched to cope with diverse possible scenarios. Among them, car-following driving has been formed the groundwork of autonomous vehicle for its integrity and flexibility to other modes such as smart cruise system (SCC) and platooning. Although the field has a rich history, most researches has been focused on the shape of target trajectory, such as the order of interpolated polynomial, in simple single-lane situation. However, to introduce the car-following mode in urban environment, realistic situation should be reflected: multi-lane road, target's unstable driving tendency, obstacles. Therefore, the suggested car-following system includes both in-lane preceding vehicle and other factors such as side-lane targets. The algorithm is comprised of three parts: path candidate generation and optimal trajectory selection. In the first part, initial guesses of desired paths are calculated as polynomial function connecting host vehicle's state and vicinal vehicle's predicted future states. In the second part, final target trajectory is selected using quadratic cost function reflecting safeness, control input efficiency, and initial objective such as velocity. Finally, adjusted path and control input are calculated using model predictive control (MPC). The suggested algorithm's performance is verified using off-line simulation using Matlab; the results shows reasonable car-following motion planning.