• 치과방사선
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• 제25권1호
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• pp.17-25
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• 1995

The purpose of this study was to obtain some informations for the radiographic differential diagnosis between odontogenic keratocyst and unicystic ameloblastoma in the mandible. The author compared and analysed the clinico-radiographic features of 48 cases of odontogenic keratocyst and 32 cases of unicystic ameloblastoma. The obtained results were as follows : 1. Odontogenic keratocyst and unicystic ameloblastoma occurred the most frequently in the 2nd and 3rd decades, and both lesions occurred with slight predilection in males. The most frequent lesional site was molar area in odontogenic keratocyst(50.0％) and mandibular angle and ramus area in unicystic amelobla-stoma(71.9％). 2. Cortical thinning and expansion were observed with similar occurrences in odontogenic keratocyst(77.l％) and in unicystic ameloblastoma(72.9％). 3. Typical undulating lesional border was observed more frequently in odontogenic keratocyst(79.2％) than in unicystic ameloblastoma(46.9％). 4. Well-defined lesional outline occurred more frequently in odontogenic keratocyst(97.9％) than in unicystic ameloblastoma(53.1％). 5. Root resorption of adjacent teeth occurred more frequently in unicystic ameloblastoma(65.2％) than in odontogenic keratocyst(18.8％) respectively, but loss of lamina dura was frequently observed in odontogenic keratocyst(79.2％). And tooth displacement occurred more frequently in odontogenic keratocyst(50.0％) than in unicystic ameloblastoma(17.4％). 6. Displacement of mandibular canal occurred more frequently in odontogenic keratocyst(75.0％) than in unicystic ameloblastoma(61.5％). 7. Inhomogeneous lesional radiolucency occurred more frequently in unicystic ameloblastoma(53.l％) than in odontogenic keratocyst(39.6％).

• Imaging Science in Dentistry
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• 제30권4호
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• pp.249-254
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• 2000

Purpose: To clarify the clinical and radiologic parameters that can be used to differentiate odontogenic keratocyst and ameloblastoma Materials and Methods: The records of 46 patients of ameloblastoma and 48 patients of odontogenic keratocyst at the Yonsei University Dental Hospital during the period of 1979 to 1995 were retrospectively reviewed. As a possible means for differentiating between the odontogenic keratocyst and ameloblastoma, the clinical parameters and the radiologic parameters were evaluated. Results: In the clinical parameters, there was no significant difference in age, sex, and sign and symptoms (p>0.05). In the radiologic parameters, there was significant difference in site, shape of the lesion, and external root resorption of adjacent teeth (p<0.05). Conclusion: The site, shape of the lesion, and external root resorption of adjacent teeth can be the parameters to differentiate odontogenic keratocyst and ameloblastoma, but a definite differentiation of these two lesions needs a more specialized imaging modality.

• 대한두경부종양학회지
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• 제38권2호
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• pp.37-41
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• 2022

Odontogenic keratocyst (OKC) accounts for 3-11% of all odontogenic cysts. OKC is a benign intra-osseous odontogenic tumor, but what makes this cyst special is its aggressive behavior and high recurrence rate. OKC is relatively aggressive compared to other odontogenic cysts, but its malignant transformation is considered extremely rare. Squamous cell carcinoma associated with odontogenic keratocysts have rarely been reported in the medical literature. We recently experienced a case of a 63-year-old man finally confirmed with squamous cell carcinoma of the mandible, which was initially diagnosed as a benign odontogenic keratocyst. Surgical resection was performed as definitive treatment. Therefore, we present this unique case with a review of the literature.

• Imaging Science in Dentistry
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• 제32권2호
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• pp.89-97
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• 2002

Purpose: The objective of this study is to find the differentiating characteristics of ameloblastomas and odontogenic keratocysts of the jaw by analyzing computed tomography (CT) images of the lesions, clarify radiological characteristics associated with jaw lesions, and to make a diagnsis based on these findings. Materials and Methods : Test subjects were chosen among the patients who were diagnosed as having an odontogenic keratocyst or ameloblastoma at the Yonsei University Dental Hospital from January 1996 to December 2000 and had CT scans taken preoperatively. The subject pool was comprised of 51 cases of odontogenic keratocyst and 37 cases of ameloblastoma. The following measures were used for image analysis of the lesion: the anatomic location, CT pattern, mesiodistal width, buccolingual width, the ratios between mesiodistal width and buccolingual width, height, CT number, homogeneity of radiodensity, the appearance of a sclerotic rim, continuity of adjacent cortical bone, and displacement and resorption of adjacent teeth. Results: Comparing the CT patten, mesiodistal width, buccolingual width, height, CT number, homogeneity, appearance of sclerotic rim, continuity of adjacent cortical bone, there were statistically significant differences between ameloblastoma and odontogenic keratocyst test subjects (p<0.05). Comparing the ratios between mesiodistal width and buccolingual width, displacement and resorption of adjacent teeth, there were no statistically significant differences (p>0.05). Conclusion: We compared odontogenic keratocysts and ameloblastomas in CT scans. They occurred most frequently in the posterior to the ramus of the mandible. The findings of patterns of the CT images showed that size and border of lesions were more aggressive in ameloblastomas than in odontogenic keratocysts. The internal contents represented an increased attenuation area (IAA) in odontopenic keratocyst. Odontogenic keratocysts were shown to have higher CT numbers than ameloblastomas.

• Imaging Science in Dentistry
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• 제30권3호
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• pp.199-205
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• 2000

Purpose: To determine whether the significant relationship exists between radiographic appearance, whether it is unilocular or multilocular, and its corresponding clinical and histologic features by examining the odontogenic keratocyst clinically, radiologically and histologically. Materials and Methods: This study was conducted on 48 cases of odontogenic keratocyst from the files of Dental Hospital, Yonsei University for the years 1982 through 1995. Results and Conclusions : The mean age of patients was 30.5 years in the unilocular group and 35.5 years in the multilocular group. The male to female ratio was 1 : 1.06 in the unilocular group and 1 : 1.75 in the multilocular group. The chief complaint was swelling in both groups(unilocular 35.1 %, multilocular 54.5%). In the occurrence site, the border of the lesion, the displacement and external root resorption of the adjacent teeth, there were no statistically significant difference between the unilocular group and multilocular group, but in the border type, there was statistically significant difference (x²-test, p<0.05)wo recurred cases were observed among 11 cases of odontogenic keratocyst. One was unilocular case and the other was multilocular case.

• Imaging Science in Dentistry
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• 제35권1호
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• pp.51-54
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• 2005

Purpose : To acquire the useful diagnostic information through the analysis of the clinical and radiological characteristics of mandibular odontogenic keratocyst. Materials and Methods : The researchers compared and analysed the clinical and radiological features of 112 cases of mandibular odontogenic keratocyst confirmed by histopathlogic examination. Results : Mandibular odontogenic keratocysts occurred more frequently in males than in females and the incidence is the highest in the 2nd and 3rd decades. These cysts occurred in the mandibular posterior area, angle-ramus area and anterior area $51.8\%$, $31.2\%$ and $17.0\%$ respectively. These cysts had undulating border ($69.6\%$) rather than smooth border ($30.4\%$). Most of these cysts had well-defined hyperostotic border ($94.6\%$). These cysts caused cortical thinning or expansion ($78.6\%$) rather than no cortical reaction ($21.4\%$). Loss of lamina dura was observed in $72.3\%$, displacement of tooth appeared in $35.7\%$ and root resolution appeared in $12.5\%$ of cases. In $71\%$ of cases, displacement of mandibular canal was observed. Internal patterns of lesional radiolucency were even ($61.6\%$) or uneven ($38.4\%$). Conclusion : These results would be helpful in diagnosing of mandibular odontogenic keratocyst. (Korean J Oral Maxillofac Radiol 2005; 35 : 51-4)

• 대한기관식도과학회지
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• 제5권1호
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• pp.68-72
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• 1999

Odontogenic keratocyst is a central destructive lesion of the jaws characterized by a thin, fragile layer of orthokeratinizing or parakeratinizing stratified squamous epithelium. Correlation between the histologic type and the recurrence ratio remains a subject of controversy, and multiple cysts are known to be associated with the nevoid basal cell syndrome. We experienced a case of multiple odontogenic keratocyst in a 25 year-old male patient involving bilateral mandible and maxilla. The cystic mass of the right maxilla was removed by Caldwell-Luc's approach and the right mandibular mass was removed by intraoral approach but the teeth that were impacted in the mandibular bone were remained in order to prevent an iatrogenic fracture.

• Imaging Science in Dentistry
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• 제40권2호
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• pp.99-101
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• 2010

Odontogenic keratocyst (OKC) with secondary inflammation involving the maxillary sinus was presented. Radiological diagnosis of this case was made based on the various findings from the cone-beam computed tomography, computed tomography and magnetic resonance images. There were calcified materials and impacted tooth within the lumen of the lesion, which is not uncommon in OKC. Histopathologic findings confirmed this lesion as OKC with secondary inflammation.

• 대한치과의사협회지
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• 제55권7호
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• pp.489-496
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• 2017

Oral and maxillofacial cyst is defined as an pathogenic cavity with an lining epithelium and connective tissue wall. Cysts of the jaws and periapical regions vary in histogenesis, treatment and prognosis. Cysts with similar clinical and radiographic can be shown different histopathologic features. Cysts are classified into odontogenic cysts and nonodontogenic cysts. Cysts are also divied into true cysts and pseudocyst. True cysts are lined with an epithelium, however pseudocysts are not lined with epithelium. A periapical cyst, dentigerous cyst and odontogenic keratocyst is clinically common and important lesions at dental clinic.

• 대한소아치과학회지
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• 제35권4호
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• pp.731-736
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• 2008

치성각화성낭종(Odontogenic keratocyst, OKC)은 치체(dental lamina)로부터 발생하는데, 모든 악골 낭의 $5{\sim}17$% 정도를 차지하며 낭의 내부는 이장상피로부터 유래한 점액성이나 치즈양 물질인 케라틴(keratin)으로 채워져 있다. 치성낭 중 가장 높은 재발률을 보인다는 것이 이 낭의 중요한 특징이다. 간혹 기저층에서 인접 결체조직 벽으로 돌기가 증식하기도 하며 결체조직 벽 내에 존재하는 치성 상피조직 섬의 증식이 위성 소낭을 발생시키기도 한다. 이들 소낭들이 치성각화성낭종의 높은 재발률의 원인으로 여겨진다. 치성각화성낭종은 다양한 연령층에서 발견되나, 20대와 30대에서 호발한다. 남성에서 다소 호발하며 하악, 특히 제3대구 치와 하악지 부위에서 자주 발생한다. 대개 피질골의 팽융에 의해 처음 발견되며 매복치와 관련되어 있고 일반적으로는 증상이 없지만 동통과 감염이 나타날 수도 있다. 흡인시 걸쭉한 노란 치즈양 물질인 케라틴이 관찰되며 특히 재발이 잘 된다. 치성 각화낭의 중요한 특징 중의 하나는 병소가 피질골의 팽창을 많이 유발시키지 않으면서 악골의 내면을 따라 성장한다 는 것이다. 치성각화성낭종화낭은 인접 치아를 변위시키고 흡수시킬 수 있으나 함치성낭보다는 정도가 심하지 않다. 하악관을 하방으로 변위시키기도 하며 상악 병소의 경우는 상악동을 침범해서 상악동 전체를 차지하기도 한다. 본 증례는 7세 10개월 된 여아의 하악 우측 제2유구치 부위에 발생한 치성각화성낭종에 대한 증례로써 전신마취하 낭종적 출술을 시행하였다. 낭종에 포함된 제1,2유구치, 유견치 및 제1소구치 치배를 발거하였으며, 현재 공간유지장치를 장착후 주기적으로 내원중이다.