• 제목/요약/키워드: occupational health

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Oxidative DNA Damage from Nanoparticle Exposure and Its Application to Workers' Health: A Literature Review

  • Rim, Kyung-Taek;Song, Se-Wook;Kim, Hyeon-Yeong
    • Safety and Health at Work
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    • 제4권4호
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    • pp.177-186
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    • 2013
  • The use of nanoparticles (NPs) in industry is increasing, bringing with it a number of adverse health effects on workers. Like other chemical carcinogens, NPs can cause cancer via oxidative DNA damage. Of all the molecules vulnerable to oxidative modification by NPs, DNA has received the greatest attention, and biomarkers of exposure and effect are nearing validation. This review concentrates on studies published between 2000 and 2012 that attempted to detect oxidative DNA damage in humans, laboratory animals, and cell lines. It is important to review these studies to improve the current understanding of the oxidative DNA damage caused by NP exposure in the workplace. In addition to examining studies on oxidative damage, this review briefly describes NPs, giving some examples of their adverse effects, and reviews occupational exposure assessments and approaches to minimizing exposure (e.g., personal protective equipment and engineering controls such as fume hoods). Current recommendations to minimize exposure are largely based on common sense, analogy to ultrafine material toxicity, and general health and safety recommendations.

화학제품 제조업 보건관리자의 직무 스트레스 (Job Stress of Occupational Health Managers in Chemicals Manufacturing Factories)

  • 김기웅;박진우;송세욱
    • 한국직업건강간호학회지
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    • 제21권3호
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    • pp.192-200
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    • 2012
  • Purpose: The purpose of this study aimed to investigate job stress levels of occupational health managers and whether job stress levels were affected by various factors such as size and types of company and work-related characteristics of occupational health managers. Methods: The study was conducted from May to September 2011 in the chemicals manufacturing factories in Korea and total subjects were 59 occupational health managers. We measured job stress levels of occupational health managers using Korean occupational stress scale (KOSS) questionnaires and the information of company characteristics was obtained using a self-reported questionnaire. Results: The characteristics of company such as type, size and industries and job characteristics of occupational health managers were significant factors in job stress. Job demand, job control, job insecurity, organizational system and occupational environment scores were significantly associated with type, size and industries of company. In multiple regression analyses, we found that job demand was significantly associated with occupational position and type of company, and job insecurity was significantly associated with working hour. Also, we found that lack of reward was significantly associated with education level, speciality, duration of work and hour and type of company. Conclusion: These results indicate that job stress of occupational health managers is significantly associated with work-related characteristics and company's characteristics.

현상학적 방법에 의한 소규모 사업장 산업간호활동에 관한 연구 (A Study on Occupational Nursing Services in Small Sacle Industry with Reference to Phenomenological Study)

  • 정문희;조정민;이수연
    • 한국보건간호학회지
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    • 제12권1호
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    • pp.13-22
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    • 1998
  • This study was conducted to find qualitative approaches to occupational reference to group health practices. In-depth interviewing was done on 8 subjects health monitor members, owners and occupational nurses, respectively). The major findings were as follows; 1. Visiting health management Useful services were 'health counseling', 'medical examination', 'providing informations about managing diseases', 'agency business in relation to Labour Ministry' and 'giving a recognition about occupational health service to owners'. Insufficiencies were 'lack of treatment service after medical examination' and 'lack of follow up services constantly'. 2. Occupational nursing service Useful services were 'providing health information' and 'counselling about health'. Major contents of occupational nursing services were 'management of occupational and adult diseases' and 'explanation of the results after medical examination'. Insufficiencies were 'deficiency of the place where group health education could be performed', 'lack of additional or closer examinations needed in counselling' and 'discontinuous selection of additional or more exact examinations'. 3. Health monitor members Health monitor members in industries were classified into two. Some were selected by owners and the others were selected simply by considering their administrative abilities such as proficient management of documents. Their major tasks were to connect workers with occupational health management agencies. This study suggests that programs should be developed which enable health monitor members to cooperate with occupational nurses.

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Decision Tree of Occupational Lung Cancer Using Classification and Regression Analysis

  • Kim, Tae-Woo;Koh, Dong-Hee;Park, Chung-Yill
    • Safety and Health at Work
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    • 제1권2호
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    • pp.140-148
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    • 2010
  • Objectives: Determining the work-relatedness of lung cancer developed through occupational exposures is very difficult. Aims of the present study are to develop a decision tree of occupational lung cancer. Methods: 153 cases of lung cancer surveyed by the Occupational Safety and Health Research Institute (OSHRI) from 1992-2007 were included. The target variable was whether the case was approved as work-related lung cancer, and independent variables were age, sex, pack-years of smoking, histological type, type of industry, latency, working period and exposure material in the workplace. The Classification and Regression Test (CART) model was used in searching for predictors of occupational lung cancer. Results: In the CART model, the best predictor was exposure to known lung carcinogens. The second best predictor was 8.6 years or higher latency and the third best predictor was smoking history of less than 11.25 pack-years. The CART model must be used sparingly in deciding the work-relatedness of lung cancer because it is not absolute. Conclusion: We found that exposure to lung carcinogens, latency and smoking history were predictive factors of approval for occupational lung cancer. Further studies for work-relatedness of occupational disease are needed.

Knowledge and Risk Perceptions of Occupational Infections Among Health-care Workers in Malaysia

  • Subramanian, Ganesh Chidambar;Arip, Masita;Subramaniam, T.S. Saraswathy
    • Safety and Health at Work
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    • 제8권3호
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    • pp.246-249
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    • 2017
  • Health-care workers are at risk of exposure to occupational infections with subsequent risk of contracting diseases, disability, and even death. A systematic collection of occupational disease data is useful for monitoring current trends in work situations and disease exposures; however, these data are usually limited due to under-reporting. The objective of this study was to review literature related to knowledge, risk perceptions, and practices regarding occupational exposures to infectious diseases in Malaysian health-care settings, in particular regarding blood-borne infections, universal precautions, use of personal protective equipment, and clinical waste management. The data are useful for determining improvements in knowledge and risk perceptions among health-care workers with developments of health policies and essential interventions for prevention and control of occupational diseases.

방향족 탄화수소 화학물질 제조사업장의 MSDS 신뢰성 평가 연구 (MSDSs Reliability Evaluation in Workplaces Manufacturing Aromatic Hydrocarbon)

  • 이권섭;최진희;조지훈;최성봉;이종한;양정선
    • 한국산업보건학회지
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    • 제19권4호
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    • pp.370-380
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    • 2009
  • Reliable hazard and risk communication is needed to prevent the safety accident & occupational disease through right use of chemicals and MSDS(Material Safety Data Sheet) is mainly used as such a tool of communication. MSDS policy has been put into effect in order to prevent the safety accident & occupational disease through right use of chemicals and fulfill workers' right to know. If information on MSDS lacks reliability due to its inaccuracy, prevention of the various effects related with environmental safety & health in advance is not possible to achieve. The most essential thing regarding authoring MSDS is to exactly evaluate the composition and ingredients of the chemical and include reliability-guaranteed information. Therefore, in this study reliability was evaluated on MSDSs in 15 aromatic hydrocarbons(benzene, toluene, xylene, etc.) manufacturers and ways to secure reliability of MSDS were suggested. The results showed 93.5% of composition agreement rate and 89% of reliability on each section in MSDSs. In order to curb MSDSs with low reliability, examination on CBI(confidential business information) in MSDS, certification of MSDS, collection and verification of MSDS are suggested.

Cases Series of Malignant Lymphohematopoietic Disorder in Korean Semiconductor Industry

  • Kim, Eun-A;Lee, Hye-Eun;Ryu, Hyung-Woo;Park, Seung-Hyun;Kang, Seong-Kyu
    • Safety and Health at Work
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    • 제2권2호
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    • pp.122-134
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    • 2011
  • Objectives: Seven cases of malignant lymphohematopoietic (LHP) disorder were claimed to have developed from occupational exposure at two plants of a semiconductor company from 2007 to 2010. This study evaluated the possibility of exposure to carcinogenic agents for the cases. Methods: Clinical courses were reviewed with assessing possible exposure to carcinogenic agents related to LHP cancers. Chemicals used at six major semiconductor companies in Korea were reviewed. Airborne monitoring for chemicals, including benzene, was conducted and the ionizing radiation dose was measured from 2008 to 2010. Results: The latency of seven cases (five leukemiae, a Non-Hodgkin's lymphoma, and an aplastic anemia) ranged from 16 months to 15 years and 5 months. Most chemical measurements were at levels of less than 10% of the Korean Occupational Exposure Limit value. No carcinogens related to LHP cancers were used or detected. Complete-shielded radiation-generating devices were used, but the ionizing radiation doses were 0.20-0.22 uSv/hr (background level: 0.21 ${\mu}Sv/hr$). Airborne benzene was detected at 0.31 ppb when the detection limit was lowered as low as possible. Ethylene oxide and formaldehyde were not found in the cases' processes, while these two were determined to be among the 263 chemicals in the list that was used at the six semiconductor companies at levels lower than 0.1%. Exposures occurring before 2002 could not be assessed because of the lack of information. Conclusion: Considering the possibility of exposure to carcinogenic agents, we could not find any convincing evidence for occupational exposure in all investigated cases. However, further study is needed because the semiconductor industry is a newly developing one.

An Empirical Analysis on Labor Unions and Occupational Safety and Health Committees' Activity, and Their Relation to the Changes in Occupational Injury and Illness Rate

  • Yi, Kwan-Hyung;Cho, Hm-Hak;Kim, Ji-Yun
    • Safety and Health at Work
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    • 제2권4호
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    • pp.321-327
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    • 2011
  • Objectives: To find out from an analysis of empirical data the levels of influence, which a labor union (LU) and Occupational Safety and Health Committee (OSHC) have in reducing the occupational injury and illness rate (OIIR) through their accident prevention activities in manufacturing industries with five or more employees. Methods: The empirical data used in this study are the Occupational Safety and Health Tendency survey data, Occupational Accident Compensation data and labor productivity and sales data for the years 2003 to 2007. By matching these three sources of data, a final data set (n = 280) was developed and analyzed using SPSS version 18 (SPSS Inc., Chicago, IL, USA). Results: It was found that a workplace with a LU has a lower OIIR than one without a LU. In manufacturing industries with five or more employees in 2007, the OIIR of the workplaces without a LU was 0.87%, while that of workplaces with a LU was much lower at 0.45%. In addition, workplaces with an established OSHC had a lower OIIR than those without an OSHC. Conclusion: It was found that the OIIR of workplaces with a LU is lower than those without a LU. Moreover, those with the OSHC usually had a lower OIIR than those without. The workplace OIIR may have an impact on management performance because the rate is negatively correlated with labor productivity and sales. In the long run, the OIIR of workplaces will be reduced when workers and employers join forces and recognize that the safety and health activities of the workplace are necessary, not only for securing the health rights of the workers, but also for raising labor productivity.

Inhalation Toxicity of 1-Bromoprpane (1-BP)

  • Kim, Hyeon-Yeong;Lee, Jun-Yeon;Lim, Cheol-Hong;Chung, Yong-Hyun;Han, Jung-Hee;Jeong, Jae-Hwang;Lee, Sung-Bae;Jhoon, Yoon-Sook;Lee, Yong-Muk
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2001년도 International Symposium on Signal transduction in Toxicology
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    • pp.126-126
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    • 2001
  • The purpose of this study was to investigate the acute(4 hrs) and repeated-dose(6 hrs a day, 5 days a week, 8 weeks) toxic effects of 1-bromopropane(1-BP) on Sprague-Dawley (SD) rats which were treated by inhalation. The results were as follows ;(omitted)

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