• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.14 no.1
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• pp.99-118
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• 2019

Objectives : The purpose of this study was to analyze trends of posture pattern in Korean literature. Methods : We searched four Korean databases (NDSL, RISS, OASIS, and KISTI) and classified the studies according to publication year and the study type. Additionally, we analyzed clinical research papers according to the predominant reported posture pattern, the type of study, assessment for clinical outcomes. Results : In total, 50 published studies were included in our analysis, and we determined the following: By study type, there were 37 interventional studies, 6 observational studies and 7 non-clinical research papers. In the interventional studies, the most common posture pattern was the forward head posture pattern, which was investigated in 22 studies. As a tool for evaluating posture pattern, cervical vertebral angle and the height of the scapula inferior angle are used most. Conclusions : Although this study has provided insight into the commonly investigated posture patterns types in Korean clinical studies, further research is required and future studies should include randomized controlled trials and systematic reviews in their analyses.

• Korean Journal of Clinical Pharmacy
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• v.24 no.3
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• pp.213-218
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• 2014

Objectives: The aim of this study was to identify the causal relationship between use of levocetrizine or cetrizine, and liver injury, by comparing frequency and pattern of hepatotoxicity in levocetrizine or cetrizine prescribed patients. Methods: This is a retrospective observational study, using data retrieved from electronic medical record system. Among 1164 patients prescribed levocetrizine or cetrizine during study period (Jul, 2009 - Jun, 2010) at Seoul National University Hospital, 543 patients with more than 4- time liver function test (LFT) results were included in final analysis. Liver injury was defined as greater than 3 times elevated level of alanine aminotransferase or 2 times elevated level of alkaline phosphatase or total bilirubin, compared to upper limit of normal, in patient with normal liver function at baseline. The frequency and pattern of liver injury were assessed. Results: Incidence of liver injury in patients prescribed with levotcetrizine or cetrizine were 1.48% and 2.94%, respectively. With few exceptions, most injuries were shown to be hepatocellular type. Rapid recovery was observed after drug cessation and long term use tends to be associated with incidence of liver injury. In patient with digestive system disorder, rate of liver injury was significantly higher (p=0.011). Conclusion: The result of this study implies potential need of liver toxicity monitoring, especially in patients taking long term levecetrizine or cetrizine or in patient with digestive system disorder. However, prospective large scale observational study is needed to confirm liver injury associated with the use of levocetirizine or cetirizine.

• CELLMED
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• v.13 no.6
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• pp.4.1-4.10
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• 2023

Background and objective: Cervicitis are an inflammatory condition of the cervix. This may be acute, chronic, active & specific or non-specific, which may cause various sign & symptoms. Abnormal vaginal discharge, lower abdominal pain, lower backache, post coital bleeding. If not treated timely it causes various complications viz PID, infertility, endometritis, ectopic pregnancy etc. Hence it has been decided to conduct a clinical trial for its management. Method: This study was an open observational study. The entire patients were allocated by considering the criteria of inclusion & exclusion. Marhame dakhilyun with roghane sausan is given 10 mg as ḥamūl at bed time, after menses for 21 days. All the patients were assessed by primary outcome of abnormal vaginal discharge, lower abdominal pain, lower backache, post coital bleeding & secondary outcomes of vaginal symptoms scale score (VSS) which score the vaginal discharge with QOL in cervicitis patients and vaginal analogue scale (VAS) for pain. Result: In this present study, marked improvement is observed in cervicitis. The mean ± SD of vaginal discharge before & after treatment is 2.57±0.050, 0.33±0.48 respectively which is highly significant with p value of<0.0001^**. VSS score before & after treatment is 21.27±6.12, 7.47±2.48 respectively with p<0.0001^** which is highly significant. VAS score used for LAB & LPA before & after treatment is 6.63±1.09, 1.90±1.29 respectively with p<0.0001^** which is highly significant. Interpretation & Conclusion: The study revealed that the formulation has been found effective in healing congestion, hypertrophied of the cervix and discharge and relieving the others associated symptoms of cervicitis. It is useful and provided immediate and effective treatment for cervicitis. Hence, the trial drug can be recommended for its management.

• Journal of Korean Medicine Rehabilitation
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• v.33 no.3
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• pp.129-134
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• 2023

Objectives The purpose of this study was to review the studies of catgut embedding related to obesity treatment. Methods We searched the papers with key words of obesity and catgut embedding via searching Research Information Sharing Service, DBpia, Koreanstudies Information Service System, Oriental Medicine Advanced Searching Integrated System, Scopus, PubMed. Additional data including study design, study topics, characteristics of participants and treatment, outcomes was extracted from full text of each study. Results There were nine studies about the catgut embedding related to obesity treatment. Five articles were conducted in China, two articles were conducted in Mexico, and two articles was published in Korea. Analysis of seven experimental studies and two observational studies were conducted to describe each research subject, method, and research results. Conclusions More interest and further research will be needed on catgut embedding related to obesity treatment in the Korean medicine to achieve clinical application and to develop treatment protocols for the obesity disease.

• Journal of Internet Computing and Services
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• v.18 no.5
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• pp.55-60
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• 2017

The pulmonary function test (PFT) is an essential data source for evaluating the effect of drugs on the lungs or the status of lung function. However, the numeric values of PFT cannot be easily used for clinical studies without labor-intensive manual efforts, because PFTs are usually recorded as image files. This study was aimed at constructing a de-identified, open-access PFT database with various clinical information. For constructing the PFT database, optical character recognition (OCR), regular expression, and the parsing technique were used to extract alphanumeric data from the PFT images in a Korean tertiary teaching hospital. This longitudinal observational database contains 413,000 measurements of PFT from 183,000 patients.

• Journal of the Korean Society of Physical Medicine
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• v.17 no.1
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• pp.11-20
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• 2022

PURPOSE: A gait assessment is an important component of the rehabilitation process, and observational gait assessment (OGA) is used routinely in clinical settings. This study examined the association of OGA tools with the independent walking ability in stroke patients to determine a cutoff value of the OGA tool according to independence levels of stroke patient gait. METHODS: Two hundred ten hemiparetic stroke patients participated in the study. The independence of gait was identified using the Functional Ambulation Category (FAC) classifications. The walking ability was assessed using OGA tools (Rivermead Visual Gait Assessment [RVGA], Wisconsin Gait Scale [WGS], Tinetti Gait Scale [TGS], and Functional Gait Analysis [FGA]). RESULTS: Stepwise multiple regression analysis showed that among the OGA tools, the FGA correlated with the FAC. The FGA explained approximately 77% of the variance in FAC. In distinguishing the independence levels, the cutoff values were as follows: between FAC 1 and FAC 0 was .5 points; between FAC 2 and lower levels, 5.5; between FAC 3 and lower levels, 11.5; between FAC 4 and lower levels, 14.5; and between FAC 5 and lower levels, 18.5. Items 1, 2, 3, and 10 were identified as explaining most of the variance in the FGA in the stepwise multiple regression. CONCLUSION: The present study found that the FGA is an assessment tool related to the level of gait independence after stroke. Furthermore, the FGA total score can serve as an index of the increase in independence level after stroke.

• Journal of Acupuncture Research
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• v.31 no.4
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• pp.21-28
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• 2014

Objectives : Lumbar disc herniations are common conditions which induce severe pain and disability. We assessed the clinical effectiveness of Korean medical combination treatment. Methods : This is an observational study. We reviewed the medical records of 46 patients with lumbar disc herniations, who attended intensive Korean medical combination treatments at Mokhuri Neck and Back Hospital, Korea during March, 2012 to October, 2012. All the patients took combination treatments of acupuncture, Chuna and herbal medicines during the hospitalization treatments. Zero to ten pain numerating rating scale(NRS) of pain and SF-36 were assessed before and after treatments. Results : During the period, 46 patients with lumbar disc herniation participated in the treatments, respectively. Average admission duration were 20.32 days(SD 9.67) in lumbar disc patients. For lumbar patients, low back pain NRS decreased from $5.84{\pm}2.58$ to $2.12{\pm}1.74$(p<0.001) and radiating pain from $6.25{\pm}2.30$ to $2.59{\pm}1.97$(p<0.001). Total SF-36 score increased significantly after treatment in lumbar disc patients(p<0.001). Conclusions : Korean medical combination treatment might be effective in reducing pain and improving life quality of patients with lumbar disc herniation.

• Journal of Korean Biological Nursing Science
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• v.16 no.4
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• pp.267-275
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• 2014

Purpose: The practice of enteral nutrition with gastric residual volumes (GRVs) as a clinical indicator is poorly standardized in intensive care units. This study aims to summarize the results from studies that evaluated the clinical outcomes related to the GRVs. Methods: This systematic review study analyzed 11 studies consisting of four randomized controlled trials, one non-randomized controlled trial, and six observational studies. Results: No consistent relationship between GRV thresholds and clinical outcomes was observed. Higher GRVs were not consistently correlated with clinical outcomes such as higher gastrointestinal complications, aspiration pneumonia, or mortality. Higher GRVs significantly generate complications more often. Findings show that a single GRV more than 200 mL or two consecutive GRVs more than 150 mL should raise concern about negative consequences. Conclusion: Critical care nurses need to monitor GRVs closely during their practice of enteral nutrition. For critically ill patients receiving enteral nutrition, a GRV threshold of 200 ml would be a desirable limit to provide safe and adequate nutrition with a conservative approach.

• Clinical and Experimental Pediatrics
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• v.64 no.3
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• pp.130-135
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• 2021

Background: The clinical significance of lip-tie, or a tethered maxillary frenulum, remains under debate. Clinicians and parents are often perplexed when deciding whether procedures available to relieve a seemingly tight or severe maxillary frenulum are needed. Purpose: No previous studies have assessed the consequences of not subjecting a tethered maxillary frenulum in newborns to surgical intervention. This study aimed to contribute the first prospective trial on this topic with a relatively extended follow-up of these newborn infants. Methods: This prospective observational questionnaire-based cohort trial was performed in a community setting and aimed to determine whether lip-tie is associated with an increased likelihood of eventual feeding or oral disorders. Results: The convenience sample comprised of 61 consecutively arriving infants with concomitant tethered frenula who were treated at the clinic for various reasons. This cohort was compared with a random sample of 66 age-matched children for a mean follow-up period of 6.42 years. Infants undergoing oropharyngeal procedures were excluded. Awareness of a deviation in oral structures was reported by 18% of the study group versus 0% of the controls. Mothers participating in the study group (24.6%) less frequently recalled painful nipples or discomfort during breastfeeding than those in the control group (47.0%) (P<0.01). There were no intergroup differences in other types of feeding difficulty, dental hygiene, pronunciation, or speech development. Conclusion: Our findings suggest that a tethered labial frenulum is not associated with an increase in breastfeeding disturbances or oral disorders. These data encourage clinicians to question the need to intervene in cases of tethered maxillary frenula.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.25 no.4
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• pp.35-44
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• 2012

Objectives : This study was aimed to evaluate the treatment effect of psoriasis patient using pyretotherapy. Methods : The clinical study was performed using retrospective observational research method. Treatment method was pyretotherapy that optimized core temperature through herbs therapy, food therapy, excercise and life style change. In other aspects, pyretotherapy is skin cure therapy that rise core temperature, down skin temperature and open sweat gland. Results : 1. 40s years showed the most coming of clinic in the distribution of age of psoriasis patient. 2. Board type showed the most number in the classification of psoriasis. 3. Pyretotherapy was very effective results in psoriasis patient treatment. 4. Pyretotherapy showed effects of rising axillary temperature and moving facial high skin temperature toward abdominal portion. Conclusions : The author is able to say that it is possible for pyretotherapy to become new skin therapy for many skin disease, especially psoriasis.