• Title/Summary/Keyword: observational analysis

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Comparative Analysis of ABM/P-15, Bone Morphogenic Protein and Demineralized Bone Matrix after Instrumented Lumbar Interbody Fusion

  • Sathe, Ashwin;Lee, Sang-Ho;Kim, Shin-Jae;Eun, Sang Soo;Choi, Yong Soo;Lee, Shih-min;Seuk, Ju-Wan;Lee, Yoon Sun;Shin, Sang-Ha;Bae, Junseok
    • Journal of Korean Neurosurgical Society
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    • v.65 no.6
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    • pp.825-833
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    • 2022
  • Objective : ABM/P-15 (anorganic bone matrix/15-amino acid peptide fragment) is a commercially available synthetically manufactured P-15 collagen peptide fragment, that is adsorbed on ABM. This study was done to investigate the efficacy of ABM/P-15 in achieving fusion in the lumbar spine and comparing it with that of recombinant bone morphogenic protein-2 (rhBMP-2) and demineralized bone matrix (DBM). Methods : A retrospective observational study of prospectively collected data of 140 patients who underwent lumbar spinal fusion surgeries in a single specialty spine hospital between 2016 and 2020, with a minimum 6-month follow-up was conducted. Based on the material used for the augmentation of the bone graft at the fusion site, the patients were divided into three categories namely ABM/P-15, rhBMP-2, and DBM group. Results : ABM/P-15, rhBMP-2, and DBM were used in 46, 44, and 50 patients, respectively. Patient characteristics like age, gender, bone mineral density, smoking history, and presence of diabetes mellitus were comparable amongst the three groups. Average follow-up was 16.0±5.2, 17.9±9.8, and 26.2±14.9 months, respectively in ABM/P-15, rhBMP-2, and DBM groups. The fusion was achieved in 97.9%, 93.2%, and 98% patients while the average time-to-union was 4.05±2.01, 10±4.28, and 9.44±3.49 months (p<0.001), respectively for ABM/P-15, rhBMP-2, and DBM groups. The average pre-operative Visual analogue scale score was 6.93±2.42, 7.14±1.97, 7.01±2.14 (p=0.900) for ABM/P-15, rhBMP-2 and DBM groups, respectively, which reduced to 1.02±0.80, 1.21±0.96, and 0.54±0.70 (p=0.112), respectively at the last follow up. Pre-operative Oswestry disability index scores were 52.7±18.02, 55.4±16.8, and 53.56±19.6 (p=0.751) in ABM/P-15, rhBMP-2, and DBM groups, which post-operatively reduced to 33.77±15.52, 39.42±16.47, and 38.3±15.89 (p=0.412) and further to 15.74±8.3, 17.41±10.45, and 16.76±9.81 (p=0.603), respectively at the last follow-up. Conclusion : ABM/P-15 appears to achieve union significantly earlier than rhBMP-2 and DBM in lumbar spinal fusion cases while maintaining a comparable clinical and complication profile.

Solar and Interplanetary Observations and Models in Korea (국내 우주환경 자료 보유 현황: 태양·행성간 공간)

  • Oh, Suyeon;Lee, Jin-Yi;Division of Solar and Space Environment of KSSS,
    • Journal of Space Technology and Applications
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    • v.1 no.2
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    • pp.160-177
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    • 2021
  • The Solar and Space Environment Division of the Korean Space Science Society investigated the use and possession of ground and satellite observations and models of solar and planetary data operated by domestic research institutes and universities. Based on the findings, we would like to introduce observational instruments, data, and models in solar and interplanetary fields in this paper to improve understanding and use of each data and explore opportunities for interdisciplinary research. The ground and satellite observations, which require a lot of investment, were mainly held by research institutes (National Meteorological Satellite Center, Polar Research Institute, Korean Space Weather, Korea Astronomy and Space Science Institute and KAIST Satellite Research Institute), and model development was overwhelmingly carried out at Kyung Hee University. In solar and interplanetary fields, we introduce Fast Imaging Solar Spectrograph (FISS), neutron monitors, and the analysis models [for the Solar Dynamics Observatory/Atmospheric Imaging Assembly (SDO/AIA) and Hinode/X-Ray Telescope (XRT) observations] in nonequilibrium ionization state as representatives. Survey on solar and interplanetary fields can be downloaded from the website of the Korean Space Science Society (http://ksss.or.kr/). The paper makes know the importance of long-term and continuous management of space science-related materials, and hopes to contribute to enhancing the status of domestic space science data by utilizing locally produced data by various personnel participating in space science research.

Analysis of HYBE Insight's BTS Exhibition Content from the New Museology Perspective (뉴 뮤지올로지 관점의 하이브 인사이트 방탄소년단(BTS) 전시 콘텐츠 분석)

  • Kim, Su-Mi
    • Journal of Korea Entertainment Industry Association
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    • v.15 no.8
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    • pp.193-202
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    • 2021
  • HYBE Insight, opened in May 2021, is an exhibition space that visually displays and re-interprets the BTS Universe and its content. The space echoes the identity of BTS as an artist and the specificity of the cultural phenomenon they have generated. This study analyzes HYBE Insight's BTS exhibition by applying new museological theories and discourses. Based on a qualitative research methodology including literature review and observational method, the primary themes of the exhibition are follows: 1) a contextualized exhibition content presenting the identity of BTS and their music, 2) the role of the fandom Army's participation in (re) producing BTS content related to the characteristic of popular music museums, 3) the elements of convergence art and its contemporary implication, 4) and the illumination of cultural value in popular music museum management. As the pivotal theory of new museology suggests, investigating a specific exhibition based on each context it has created is significant. However, those studies, including exhibitions related to popular music/artists, were mostly developed in Western nations. In this respect, HYBE Insight's BTS exhibition provides considerable room to explore. In addition to the recent research on BTS, such as their convergent artistry, socio-cultural influence, the role of Army, and the characteristics of HYBE's content management, this article aims to contribute to the multifaceted research by scrutinizing the BTS exhibition content from the new museology perspective.

Effects of Korean Medicine on 20 Post-TKR Inpatients: A Retrospective Observational Study (슬관절 전치환술 후 한방병원에 입원한 환자 20명에 대한 후향적 분석)

  • Im, Ji-Sung;Kim, Ji-Eun;Jeong, Yeong-jin;Kang, Do-Young;Park, Eun-Sang;Kim, Jong-gyu;Song, Yung-sun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.36 no.4
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    • pp.138-142
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    • 2022
  • This study aimed to evaluate the effectiveness of Korean rehabilitation treatement for patients with post-TKR. The medical records of inpatients undergoing Korean rehabilitation treatment after TKR from 2016.01.01. to 2021.12.31. during the admission, were analyzed retrospectively. The effect of treatment was evaluated by using a numeric rating scale(NRS) and range of motion(ROM) of knee. Statistical analysis was done using the IBM SPSS statistics 26 program. If the period of hospitalization was within 7 days or change of NRS and ROM was not recorded properly, the case was excluded. All inpatients received acupuncture treatment, Electro-acupuncture. Soyeom pharmaco-acupuncture were used at a high rate. Blood letting cupping therapy, dry cupping therapy, Interferential Current Therapy(ICT) continuous passive motion(CPM), cryotherapy were used at a high rate. A significant improvement was noted when comparing the NRS and knee ROM results at the time of admission and discharge. Korean medical rehabilitation can be effectively used for patients who have undergone TKR, to relieve pain and enable returning to daily activities. It is expected to be helpful in future studies of post-TKR in Korean Medicine. Also It can be used for medical treatment of post-TKR in Korean Medicine Hospital and clinic. However, further research with a high level of evidence is necessary to support this finding.

Characteristics of poisoning patients visiting emergency departments before and after the COVID-19 pandemic (코로나바이러스감염증-19 대유행 전, 후의 응급실로 내원한 중독 환자의 특성)

  • Seung Jae Kee;Yongil Cho;Hyunggoo Kang;Tae Ho Lim;Jaehoon Oh;Byuk Sung Ko;Juncheol Lee
    • Journal of The Korean Society of Clinical Toxicology
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    • v.20 no.2
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    • pp.66-74
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    • 2022
  • Purpose: This study investigates the characteristics and prognosis of acute poisoning patients visiting nationwide emergency departments before and after the Coronavirus disease 2019 (COVID-19) pandemic. Data were obtained from the National Emergency Department Information System (NEDIS). Methods: This nationwide retrospective observational study included acute poisoning patients who visited the emergency departments between February 1 to December 31, 2020, which has been determined as the pandemic period. The same periods in 2018 and 2019 were designated as the control periods. The primary outcome assessed was the length of stay in emergency departments (EDLOS). The secondary outcomes examined were intensive care unit admission rate and in-hospital mortality rate before and after the pandemic. A subgroup analysis was performed for inpatients and intentional poisoning patients. Results: A total of 163,560 patients were included in the study. During the pandemic, the proportion of women increased from 50.0% in 2018 and 50.3% in 2019 to 52.5% in 2020. Patients aged 20-29 years increased from 13.4% in 2018 and 13.9% in 2019 to 16.6% in 2020. A rise in cases of intentional poisoning was also noted - from 33.9% in 2018 and 34.0% in 2019 to 38.4% in 2020. Evaluating the hospitalized poisoned patients revealed that the EDLOS increased from 3.8 hours in 2018 and 3.7 hours in 2019 to 4.2 hours in 2020. ICU admissions were also markedly increased (2018, 48.2%; 2019, 51.8%; 2020, 53.2%) among hospitalized patients. Conclusion: The COVID-19 pandemic has changed the epidemiology, clinical characteristics, and prognosis of acute poisoning patients visiting nationwide emergency departments in Korea. The proportion of young adults, women, and intentional poisoning patients has increased after the COVID-19 pandemic. Prolonged length of stay at the emergency department and an increased rate of intensive care unit admissions were determined in hospitalized acute poisoning patients.

A prospective multicenter clinical study on the efficiency of detachable ball- and spring-retained implant prosthesis

  • Min-Jung Kim;Won-Tak Cho;Su-Hyun Hwang;Ji-Hyeon Bae;Eun-Bin Bae;June-Sung Shim;Jong-Eun Kim;Chang-Mo Jeong;Jung-Bo Huh
    • The Journal of Advanced Prosthodontics
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    • v.15 no.4
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    • pp.202-213
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    • 2023
  • PURPOSE. This prospective clinical study was conducted to evaluate the clinical usefulness of the freely detachable zirconia ball- and spring-retained implant prosthesis (BSRP) through a comparative analysis of screw- and cement-retained implant prosthesis (SCRP). MATERIALS AND METHODS. A multi-center, randomized, prospective clinical study evaluating the clinical usefulness of the detachable zirconia ball- and spring-retained implant prostheses was conducted. Sixty-four implant prostheses in 64 patients were examined. Periodic observational studies were conducted at 0, 3, 6, and 12 months after delivery of the implant prosthesis. Factors such as implant success rate, marginal bone resorption, periodontal pocket depth, plaque and bleeding index, and prosthetic complications were evaluated, respectively. RESULTS. During the 1-year observation period, all implants survived without functional problems and clinical mobility, showing a 100% implant success rate. Marginal bone resorption was significantly higher in the SCRP group than in the BSRP group only at the time of implant prosthesis delivery (P = .043). In all observation periods, periodontal pocket depth was slightly higher in the BSRP group than in the SCRP group, but there was no significant difference (P > .05). The modified plaque index (mPI) scores of both groups were moderate. Higher ratio of a score 2 in modified sulcus bleeding index (mBI) was observed in the BSRP group in the 6- and 12-months observation. CONCLUSION. Within the limitations of this study, the newly developed zirconia ball- and spring-retained implant prosthesis could be considered as an applicable and predictable treatment method along with the existing screw- and cement-retained prosthesis.

Statistical Analysis on Hospitalized Patients with Thoracolumbar Compression Fracture at Single Korean Medicine Hospital: Retrospective Review (일개 한방병원에서의 흉요추 압박골절 입원 환자에 대한 통계적 분석: 후향적 차트리뷰)

  • Hyun jin Jang;So jeong Kim;Min Ju Kim;Hyeon Kyu Choi;Pil Je Park;Yeon Soo Kang;Jeong Kyo Jeong;Ju Hyun Jeon;Young Il Kim
    • The Journal of Korean Medicine
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    • v.44 no.2
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    • pp.149-169
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    • 2023
  • Objectives: This study was designed to statistically analyze patients hospitalized for thoracolumbar compression fractures at Daejeon University Daejeon Korean Medicine Hospital from January 1, 2017 to December 31, 2021. Methods: A total of 62 patients were analyzed through electronic medical records in this study. The extracted data was analyzed using IBM SPSS ver.27.0. Results: 1. Traffic accident patients were more likely to reduce pain by more than half compared to falls and other patients. Patients without spinal disease were more likely to reduce pain by more than half compared to those without. The shorter the absolute bed rest and the longer the hospital stay, the higher the probability of pain reduction by more than half. 2. The duration of pain half-reduction was longer in patients with diabetes than in patients without diabetes. 3. The longer the hospitalization period and the shorter the absolute bed rest period, the less pain was reported upon discharge. Males complained of less pain at discharge than females, and patients without spinal disease complained less than those without. Patients who did not receive absolute bed rest complained of less pain upon discharge than those who did not. Conclusions: This study included patients hospitalized for thoracolumbar compression fractures and showed that etiology, absolute bed rest period, hospitalization period, gender, spinal disease, diabetes statistically affected the degree of pain reduction.

Calculating Sea Surface Wind by Considering Asymmetric Typhoon Wind Field (비대칭형 태풍 특성을 고려한 해상풍 산정)

  • Hye-In Kim;Wan-Hee Cho;Jong-Yoon Mun
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.29 no.7
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    • pp.770-778
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    • 2023
  • Sea surface wind is an important variable for elucidating the atmospheric-ocean interactions and predicting the dangerous weather conditions caused by oceans. Accurate sea surface wind data are required for making correct predictions; however, there are limited observational datasets for oceans. Therefore, this study aimed to obtain long-period high-resolution sea surface wind data. First, the ERA5 reanalysis wind field, which can be used for a long period at a high resolution, was regridded and synthesized using the asymmetric typhoon wind field calculated via the Generalized Asymmetric Holland Model of the numerical model named ADvanced CIRCulation model. The accuracy of the asymmetric typhoon synthesized wind field was evaluated using data obtained from Korea Meteorological Administration and Japan Meteorological Administration. As a result of the evaluation, it was found that the asymmetric typhoon synthetic wind field reproduce observations relatively well, compared with ERA5 reanalysis wind field and symmetric typhoon synthetic wind field calculated by the Holland model. The sea surface wind data produced in this study are expected to be useful for obtaining storm surge data and conducting frequency analysis of storm surges and sea surface winds in the future.

Validation of Satellite Altimeter-Observed Sea Surface Height Using Measurements from the Ieodo Ocean Research Station (이어도 해양과학기지 관측 자료를 활용한 인공위성 고도계 해수면고도 검증)

  • Hye-Jin Woo;Kyung-Ae Park;Kwang-Young Jeong;Seok Jae Gwon;Hyun-Ju Oh
    • Korean Journal of Remote Sensing
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    • v.39 no.5_1
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    • pp.467-479
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    • 2023
  • Satellite altimeters have continuously observed sea surface height (SSH) in the global ocean for the past 30 years, providing clear evidence of the rise in global mean sea level based on observational data. Accurate altimeter-observed SSH is essential to study the spatial and temporal variability of SSH in regional seas. In this study, we used measurements from the Ieodo Ocean Research Station (IORS) and validate SSHs observed by satellite altimeters (Envisat, Jason-1, Jason-2, SARAL, Jason-3, and Sentinel-3A/B). Bias and root mean square error of SSH for each satellite ranged from 1.58 to 4.69 cm and 6.33 to 9.67 cm, respectively. As the matchup distance between satellite ground tracks and the IORS increased, the error of satellite SSHs significantly amplified. In order to validate the correction of the tide and atmospheric effect of the satellite data, the tide was estimated using harmonic analysis, and inverse barometer effect was calculated using atmospheric pressure data at the IORS. To achieve accurate tidal corrections for satellite SSH data in the seas around the Korean Peninsula, it was confirmed that improving the accuracy of tide data used in satellites is necessary.

Enhancing GEMS Surface Reflectance in Snow-Covered Regions through Combined of GeoKompsat-2A/2B Data (천리안 위성자료 융합을 통한 적설역에서의 GEMS 지표면 반사도 개선 연구)

  • Suyoung Sim;Daeseong Jung;Jongho Woo;Nayeon Kim;Sungwoo Park;Hyunkee Hong;Kyung-Soo Han
    • Korean Journal of Remote Sensing
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    • v.39 no.6_1
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    • pp.1497-1503
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    • 2023
  • To address challenges in classifying clouds and snow cover when calculating ground reflectance in Near-UltraViolet (UV) wavelengths, this study introduces a methodology that combines cloud data from the Geostationary Environmental Monitoring Spectrometer (GEMS) and the Advanced Meteorological Imager (AMI)satellites for snow cover analysis. The proposed approach aims to enhance the quality of surface reflectance calculations, and combined cloud data were generated by integrating GEMS cloud data with AMI cloud detection data. When applied to compute GEMS surface reflectance, this fusion approach significantly mitigated underestimation issues compared to using only GEMS cloud data in snow-covered regions, resulting in an approximately 17% improvement across the entire observational area. The findings of this study highlight the potential to address persistent underestimation challenges in snow areas by employing fused cloud data, consequently enhancing the accuracy of other Level-2 products based on improved surface reflectivity.