• 제목/요약/키워드: obesity condition

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마우스를 이용한 비만연구에서 활용되는 물리적 표현형 분석 기술 (Physical Phenotype Analysis in Obesity Study in vivo)

  • 김현경;고광웅
    • 식품과학과 산업
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    • 제51권1호
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    • pp.37-44
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    • 2018
  • The prevalence of obesity is continually increasing in South Korea; about 1/3 of adults are diagnosed with obesity and 1/2 of adults are overweight in 2016. Abnormal body fat mass increased the risk factors of metabolic syndrome (including hypertension, type II diabetes, dyslipidemia), chronic kidney failure, osteoarthritis, and cardiovascular disease. Ministry of Food and Drug Safety (MFDS) in Korea established the validation and approval system for "functional food" based on related laws and regulations. According to the guideline of MFDS, the biomarkers for obesity study in vitro, in vivo, and clinical trial are well summarized. The analysis of physical phenotypes is necessary condition to study further molecular phenotypes and pathway analysis in vivo study. Thus, we will review currently available physical phenotype analysis; dual energy X-ray absorptiometry (DEXA) and Oxylet gas analysis will be examined in-depth.

태음인(太陰人) 병증(病證) 분류(分類)에 근거한 비만환자 치험 4례 (Approaching obesity through constitutional therapy: a series of 4 obesity cases who were classified as the Taeeum constitutional type)

  • 박윤성;신현상;이준희;이의주;고병희
    • 사상체질의학회지
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    • 제23권2호
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    • pp.263-274
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    • 2011
  • 1. Objectives: We report a series of 4 obesity cases who responded well to the weight-loss therapy based on the Taeeum Sasang constitutional therapy. 2. Methods: In treating 4 obese patients who were constitutionally typed as the Taeeum type, Case 1 and Case 2 fell into the category of the Lung Dry-Cold symptomatology, Case 3 into the Dry-Heat symptomatology, and Case 4 into the Exterior-Interior Combined symptomatology. Each patient was given Sasang medication according to protocol: Taeeumjowi-tang (Taiyintiaowei-tang) to Case 1 and Case 2, Cheongpyesagan-tang (Qingfeixiegan-tang) to Case 3, and Seunggijowi-tang (Chengqitiaowei-tang) to Case 4. On each visit to the clinic (7-21 times in total), the patients were checked on their general condition and change in body weight. 3. Results and Conclusions: All patients showed improvements in their general condition and a satisfactory decrease in weight (Case 1 showed a decrease of 12.7 kg in 84 days, Case 2 a decrease of 8.9 kg in 39 days, Case 3 a decrease of 33 kg in 250 days, and Case 4 a decrease of 29.3 kg in 155 days). Treating obesity based on Taeeum constitutional therapy was found to be effective for weight loss and general improvement of health. The sustained effects of the therapy should be checked during the following visits. The obesity treatment protocol suggested in this investigation should be explored and verified in future studies.

과체중 및 비만 성인 여성의 비만변증 설문 결과 분석 (Analysis of Oriental Obesity Pattern Identification Questionnaire on Overweight and Obese Korean Adult Women)

  • 황미자;문진석;박경수;송미연
    • 한방비만학회지
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    • 제8권2호
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    • pp.63-72
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    • 2008
  • Objectives We aimed to explore obesity pattern among overweight and obese Korean adult women using oriental obesity pattern identification questionnaire. Methods This survey was performed using data of 83 overweight and obese women aged from 20 to 55 yrs (BMI ${\geq}\;23\;kg/m^2$ : n=18, BMI ${\geq}\;25\;kg/m^2$ :n=65) in Seoul, from 2007 to 2008. Subjects were given written consent and this study was performed under the permission of institutional review board of Kyung-Hee East-west Neo Medical Center. Results 1. The distribution of oriental obesity pattern identification did not show any differences between obese and overweight group(p>0.05). 2. The ratio of significantly-scored oriental pattern identification was ordered by Stagnation of the liver Qi(肝欝, 21.7%) > Indigestion(食積, 18.1%) > Spleen deficiency(脾虚, 16.9%) > Yang deficiency(陽虚, 14.5%) (n=83). 3. The frequency of top-scored oriental obesity pattern was ordered by Stagnation of the liver Qi(肝欝, 36.1%) > Indigestion(食積, 24.1%) > Yang deficiency (陽虚, 15.7%) (n=83). 4. The frequency of oriental obesity pattern identification was ordered by Stagnation of the liver Qi(肝欝, 41.7%) > Indigestion(食積, 29.2%) > Yang deficiency(陽虚, 12.5%) > Stagnation of the liver Qi and Yang deficiency(肝欝兼陽虚, 8.3%) (n=24). Conclusions In Korean adult overweight and obese women, Stagnation of the liver Qi(肝欝), Indigestion(食積), and Yang deficiency (陽虚) were found to be the main pathology based on oriental obesity pattern identification questionnaire. It suggests that not only physical status but also general condition and emotional problem should be concerned in treatment of obesity. This study could play a role as a preliminary data of oriental obesity pattern identification.

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비만 또는 고혈당 증상 보유에 따른 대사성증후군의 식습관 및 영양상태 비교 (Comparison of Dietary Habits and Nutrient Intakes in Subjects with Obesity or Hyperglycemia Classified Metabolic Syndrome)

  • 박정아;윤진숙
    • Journal of Nutrition and Health
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    • 제38권8호
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    • pp.672-681
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    • 2005
  • Metabolic syndrome (MS) was defined as condition in which the subjects have two or more abnormalities among obesity, hyperlipidemia, hypertension and hyperglycemia. To develop a nutritional education program for MS, this study was performed to compare the dietary habits and nutrients intake of complex symptoms of MS with obesity or hyper-glycemia. The participants in this study were 84 normal adults,62 MS with obesity, 33 MS with hyperglycemia and 54 MS with obesity and hyperglycemia (OB + HG). A dietary survey was conducted using 24-hour recall method. Total cholesterol level of MS with obesity group was significantly higher than other groups. WHR and systolic blood pressure showed no significant difference among MS with obesity, hyperglycemia and OB+HG groups. Dietary intakes of energy, Fe, Vit A, Vit $B_2$ and Ca were less than $75\%$ of 7th Korean RDA in the all groups. Especially, dietary intakes of Vit $B_2$, Vit A and Ca were less than $50\%$ of RDA in MS with hyperglycemia and OB+HG groups. The other nutrient intakes of each group were also below the RDA level except for P, Vit C. It appeared that most of the nutrient intakes in MS with hyperglycemia and OB + HG groups were significantly lower than normal group. In MS with obesity group, each consumption of sweet, organ meat and soup was higher than other groups. Each consumption of garlic and onion in MS with obesity, hyperglycemia and OB + HG groups was lower than normal group. Also, each consumption of soup in MS with hyperglycemia and OB + HG groups was higher than normal group. Indices of nutritional quality (INQ) for Ca, Vit A and Vit $B_2$ were below 1 in all the groups. Food composition group score of MS with hyperglycemia group was significantly lower than normal and MS with obesity groups. Our results indicated that nutritional education program for MS with obesity or hyperglycemia should include specific strategies to modify unsound dietary habits and inappropriate food intake for health.

복부비만과 위험음주가 성인의 고혈압에 미치는 영향 (Effects of Abdominal Obesity and Risk Drinking on the Hypertension Risk in Korean Adults)

  • 이은숙
    • 지역사회간호학회지
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    • 제29권3호
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    • pp.349-358
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    • 2018
  • Purpose: This study was conducted to investigate the combined effects of abdominal obesity and alcohol drinking on the risk of hypertension in Korean adults (aged ${\geq}30yrs$). Methods: Data of 13,885 subjects from the sixth Korea National Health and Nutrition Examination Survey were analyzed. The multiple logistic regression tests were used for the analysis, including potential covariates of the model. Results: Frequency of drinking, typical drinking quantity, and frequency of binge drinking had a positive relation to hypertension. The odds ratio of hypertension for risk drinkers with abdominal obesity was 4.81 compared to non-risk drinkers with normal waist circumstance, whereas the odds ratios of hypertension for risk drinkers with normal waist circumstance and non-risk drinkers with abdominal obesity were 1.58 and 2.37 respectively. Conclusion: Both abdominal obesity and alcohol drinking patterns were strong risk factors of hypertension in the Korean adults. Risk drinkers with abdominal obesity showed a marked high risk in hypertension compared to those with a single condition alone.

아동 . 청소년기 식이패턴 분석과 복부비만에 영향을 미치는 요인 - 1998, 2001, 2005년 국민건강.영양조사 자료를 근거하여 - (Dietary Pattern Analysis and Factors Affecting Abdominal Obesity in Children and Adolescents)

  • 백경원
    • 한국학교보건학회지
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    • 제22권2호
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    • pp.137-146
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    • 2009
  • Purpose: This study was performed to identify the socioeconomic factors, the health behavior factors and dietary pattern that have an influence on abdominal obesity, as measured by using the waist circumference in children and adolescents. Methods: This study used data collected from 1998, 2001, 2005 Korean National Health and Nutrition Examination Survey (NHANES). Final sample included 3,596 subjects from 10 to 19 years old who had completed necessary health examinations, health behaviors survey, and nutrition survey. Results: 12 dietary patterns emerged from factor analysis with different factor loading. Logistic regression analysis of the factors that affect abdominal obesity showed that the education level, BMI(Body Mass Index) and dietary pattern, 'Kimchi' including Korean cabbage and radish affected the abdominal obesity in children and adolescents. Conclusions: Abdominal obesity is a risk factor for morbidity and mortality, and it is associated with chronic diseases, including cardiovascular disease and diabetes. Based on the findings, it is essential to modify dietary pattern for preventing abdominal obesity, which is a condition associated with the incidence of chronic disease in adults.

초등학교 아동의 비만 실태 및 관련요인 -대구시 일 초등학교 고학년을 중심으로- (Study on an Actual Condition and Relevant Factors of Obesity of Elementary School Students)

  • 이종렬;박천만
    • 보건교육건강증진학회지
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    • 제21권2호
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    • pp.35-54
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    • 2004
  • This study was intended to provide basic data of nutrition education to a prevention of obesity and living patterns of elementary school students. Through the measurment of the actual obesity rate of children for students who were in the fifth and sixth grades of elementary school as well as their mothers, and by analyzing obesity-related factors. Children have started to have the characteristics obesity and obesity problems. 1. There were total 234 children including 133 boys (56.8%) and 101 girls (43.2%) for the study. There were 80 children in the fifth grade (34.2%) and 154 children in the sixth grade (65.8%). 2. Among the subjects 20.1% were obese. By gender, the obesity rate of boys (27.1%) was higher than that of girls (l0.9%)(p<0.01). By grade, children in the fifth grade (26.3%) had higher obesity rate than children in the sixth grade (l6.9%)(p<0.05). 3. In terms of the educational level of parents, the obesity rate of children of parents who received university and/or higher education was 27.5% (p<0.05). 44.1% of parents answered ‘I almost never give snack’s’(p<0.01). 4. There was 32.8% for an irregular quantity of meal. There was no obese child who under-ate (p<0.05). In terms of impulse eating, ‘I eat.’ and ‘I don't eat.’ were 24.4% and 25.9% respectively. The obesity rate of the case of ‘I eat only food I like.’ was 10.6% (p<0.05). In terms of the obesity rate based on the daily average meal frequency, there was the highest rate of 26.1% for I average meal frequency per day, 13.0% for 2 daily average meal frequency, and 7.4% for over 3 average meal frequency per day (p<0.05). For a degree of a physical activity, the group of active physical activity (p<0.05) and the group which liked the physical exercise showed a lower obesity rate (p<0.001). The obesity rate of children who had regular exercise was 11.8%. It was lower than the obesity rate (24.8%) of children who didn't exercise (p<0.01). The higher exercise frequency per week was, the lower the obesity rate was(p<0.01). In terms of the exercise time, there was 8.3% for over 60 minutes and 28.9% for less 15 minutes. The group which had the long exercise time showed a lower obesity rate(p<0.05). As the result, the education for obesity must enable students to recognize the warning signs for obesity and control their own weight with proper living patterns, by modifying behaviors considering the degree of obesity. Obesity must be controlled by the prevention and education connected with the family for all students as one of the school health programs. There must be also the development of a program through individual consultation considering the degree of obesity.

미국 버지니아주 거주 한국인과 미국인의 건강상태 인식도 및 짠맛 기호도 비교 (A Study on the Level of Perception of the Health Condition of Koreans and Americans in Virginia, USA and Their Preference for Salty Taste)

  • 김미옥
    • 한국식품영양학회지
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    • 제27권4호
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    • pp.716-724
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    • 2014
  • This study was conducted as a comparative analysis, using the SPSS 17.0 program for a survey conducted from March to July 2013, on the level of perception and preference factors of Koreans and Americans residing in Virginia, USA(89 male and female adults of 20 years of age or above). For the information on the degree of obesity, a survey was used and the subjects provided with their heights and weights. The researcher used this data to calculated their BMI and distinguished the degrees of obesity. For the BMI, the obesity diagnosis of Korean Society for the Study of Obesity was used for Koreans, and the WHO's obesity diagnosis on adults were employed for Americans. First, regarding the Korean participants, the level of obesity appeared in the order of normal (79.6%), overweight (14.3%), and underweight (6.1%). Also, the level of perceptions of their health conditions appeared in the order of average (51.7%) and good (34.7%). No one perceived their health to be in poor condition. Meanwhile, for the American participants, the order was as follows: overweight at about 45%, normal weight at about 35%, obesity at about 12.5%, and underweight at about 7.5%. In terms of the level of perception of health during ordinary times, about 55% of the American participants answered that they are in good health. Therefore, the Americans were found to perceive their health to be in relatively better condition than the Koreans residing in the USA. Also, concerning the level of interest in health while eating food at ordinary times, the American participants were discovered to be more interested (about 62.5%) than the Korean participants. The research on their preference for salty taste was conducted as a survey, and the subjects were asked to choose an item according to their subjective feeling. Regarding the preference for salty taste, both Koreans and Americans residing in the USA responded as moderate. However, a higher proportion of Americans than Koreans responded to favor salty taste. Concerning the reason for their preference for salty taste, Koreans responded with various reasons whereas Americans mostly responded that it is because they eat salty food frequently. For any changes in dietary behavior related to eating salty food, both Korean and American respondents thought that the amount of their daily intake of salt is appropriate and that they consider taste as most important in selecting a snack. Based on the above data, the results of this research indicate a need for actual improvement in the diet with regard to salty food along with diverse policies for promoting life with a low salt diet in future.

대사적으로 건강한 비만 성인과 대사적으로 불건강한 비만 성인의 신체활동 및 영양소 섭취량에 관한 연구 (Study of Physical Activities and Nutrient Intakes of Adults with metabolically healthy obesity and those with metabolically unhealthy obesity)

  • 한정원
    • 한국산학기술학회논문지
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    • 제16권10호
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    • pp.7043-7052
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    • 2015
  • 본 연구는 대사적으로 건강한 비만인과 대사적으로 불건강한 비만인을 구분하여 대사적으로 건강한 비만인에게 영향을 미치는 신체활동과 영양소들을 확인하고자 시행된 연구이다. 대상자들은 2013년 1월-12월까지 실시한 제 6기 국민건강영양조사에서 참여한 대상자들이며 복합표본 로지스틱 분석을 시행하였다. 연구결과 대사적으로 건강한 비만인은 대사적으로 불건강한 비만인에 비해 1주일 동안의 유연성 운동일수(Odds ratio (OR)=1.18, 95% confidence interval (95% CI)=1.01-1.38), 수분 섭취(OR=1.04, 95% CI=1.01-1.06)및 단백질 섭취량(OR=1.07, 95% CI=1.02-1.13)이 높고, 지방(OR=0.99, 95% CI=0.98-1.00)과 탄수화물(OR=0.98, 95% CI=0.97-0.99)의 섭취량이 낮은 것으로 확인되었다. 이를 근거로 하여 비만 성인에 대한 간호중재는 대사적 상태에 따른 접근이 필요하다고 사료된다.

저체중, 정상, 마른 비만 및 비만 여대생의 식행동 및 혈액 임상지표 비교 (Comparison of Dietary Behaviors and Blood Clinical Indices in Underweight, Normal Weight, Normal Weight Obese and Obese Female College Students)

  • 이수빈;김정희
    • 대한지역사회영양학회지
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    • 제23권5호
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    • pp.431-443
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    • 2018
  • Objectives: Normal weight obesity (NWO) is defined as excessive body fat in the context of a normal body mass index (BMI). This condition carries a greater risk of developing noncommunicable chronic disease and has been associated with early inflammation. This study was conducted to compare the anthropometric measurements, eating behaviors, and blood clinical indices among four groups: underweight, normal, normal weight obesity and obesity. Methods: The subjects included 215 female college students. A questionnaire was administered regarding general characteristics, dietary behaviors, food consumption frequency. Anthropometric measurements and blood clinical indices were also investigated. Results: The average BMI, body fat percentage, waist circumference, fat-free mass, and muscle mass were highest in the obesity group (p<0.05). Most subjects had tried to lose weight and perceived that their health was worse than before they became college students. The ratio of students in the NWO group who thought their health was very poor was significantly higher than in the other three groups (p<0.05). The obesity and NWO groups seemed to eat more and their eating speed was significantly faster than the other groups (p<0.001). The consumption frequency of caffeinated beverages was significantly higher in the NWO group than in the other three groups (p<0.01). WBC was significantly higher in the obesity group (p<0.05). Serum levels of TG and total cholesterol were also significantly higher in the obesity group (p<0.05). Serum GPT was significantly higher in the obesity group (p<0.05) while BUN level was highest in the NWO group (p<0.05). Conclusions: The obesity group showed the most health problems while the NWO group seemed relatively healthy. However, NWO can lead to problems such as metabolic syndrome and cardiovascular disease in later life if poor dietary habits are maintained. Therefore, education in appropriate eating habits is needed for these subjects.