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http://dx.doi.org/10.23093/FSI.2018.51.1.37

Physical Phenotype Analysis in Obesity Study in vivo  

Kim, Hyunkyung (Department of Food and Nutrition, Hanyang University)
Go, Gwang-woong (Department of Food and Nutrition, Hanyang University)
Publication Information
Food Science and Industry / v.51, no.1, 2018 , pp. 37-44 More about this Journal
Abstract
The prevalence of obesity is continually increasing in South Korea; about 1/3 of adults are diagnosed with obesity and 1/2 of adults are overweight in 2016. Abnormal body fat mass increased the risk factors of metabolic syndrome (including hypertension, type II diabetes, dyslipidemia), chronic kidney failure, osteoarthritis, and cardiovascular disease. Ministry of Food and Drug Safety (MFDS) in Korea established the validation and approval system for "functional food" based on related laws and regulations. According to the guideline of MFDS, the biomarkers for obesity study in vitro, in vivo, and clinical trial are well summarized. The analysis of physical phenotypes is necessary condition to study further molecular phenotypes and pathway analysis in vivo study. Thus, we will review currently available physical phenotype analysis; dual energy X-ray absorptiometry (DEXA) and Oxylet gas analysis will be examined in-depth.
Keywords
body fat mass; DEXA; gas analyzer; obesity; physical phenotypes;
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