• Journal of Korean Medicine for Obesity Research
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• v.2 no.1
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• pp.95-104
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• 2002

Objects. There was an increase in obese population due to eating habits resulted in modernization of lifestyle and the change of the tendency to conduct the physical activity, in order words, the reduction in the range of kinetic energy. Obesity is viewed as a major risk factor for serious health problems, including heart disease, high blood pressure, stroke, diabetes, and certain forms of cancer as well as for psychological and social problems owing to our fat-phobic society. In the present study, we investigate the weight loss thanks to giving Handayulso-tang(HD) medication of Taeum-in to induced obesity rats and its effects on lipid metabolism, given that their behavior patterns are changed according to their constitution. Methods: The extracts of Handayulso-tang was orally administered to the rats of HD group 200mg/200g of rats weight every day for 6 weeks, and the control group were fed with equal amount of saline. And measured the body weight and total cholesterol, triglyceride, free fatty acid and total lipid contents in serum in obese rats. Results: 1. The body weight in HD group were decreased. 2. The contents of serum total cholesterol and triglyceride in HD group were decreased and statistically showed the significant difference compared with the control group. 3. The contents of serum free fatty acid and total lipid in HD group were decreased, but did not statistically show the significant difference compared with the control group. Conclusion: Based on the above results, we know that Handayulso-tang have effects on the decrease of the body weight and the contents of serum total cholesterol, triglyceride, free fatty acid and total lipid So it could be concluded that Handayulso-tang can help the treatment of obesity.

• Journal of Physiology & Pathology in Korean Medicine
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• v.32 no.6
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• pp.396-402
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• 2018

Hataedock (HTD) treatment is a traditional preventive therapy for the fetal toxicosis- the acute allergic disease after childbirth, mainly manifested by a variety of skin allergies such as scab, phlegm. The aim of this study was to investigate the efficacy of HTD treatments for the alleviation of inflammation in Dermatophagoides farinae-induced obese NC/Nga mice. 20 mg/kg of Coptidis Rhizoma, Glycyrrhizae Radix (CRGR) extracts as a remedy of HTD treatments were orally administered to NC/Nga mice. We induced obesity in the mice by high-fat diet. To induce skin allergies, the extracts of Dermatophagoides farinae were topically applied on the NC/Nga mice at 4th-6th and 8th-10th weeks. Structural and molecular changes in the skin tissues were measured by immunohistochemical staining. HTD treatment decreased the atopic dermatitis (AD)-like symptoms including hemorrhage, erythema, erosion, edema, and dryness. HTD treatment suppressed the mast cell activation confirmed by reduction of $Fc{\varepsilon}RI$, substance P, and serotonin. The expression of several inflammatory mediators including nuclear factor-kappa B ($NF-{\kappa}B$) p65, inducible nitric oxide synthase (iNOS), vascular endothelial growth factors (VEGFs) was also decreased by HTD treatment. HTD treatment suppressed the allergic, inflammatory responses in the skin tissues of the NC/Nga mice by reducing mast cells and down-regulating several inflammatory mediators.

• Journal of Preventive Medicine and Public Health
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• v.54 no.3
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• pp.199-207
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• 2021

Objectives: Physical inactivity is the fourth leading global risk factor for mortality, followed by obesity. The combination of these risk factors is associated with non-communicable diseases, impaired physical function, and declining mental function. The World Health Organization recommends physical activity to reduce the mortality rate. Thus, this study examined the effects on anthropometric measurements of a 12-week walking program for elderly people in Samarahan, Sarawak, Malaysia with a 7000-step goal and weekly group walking activities. Methods: A quasi-experimental study was conducted involving 109 elderly people with a body mass index (BMI) ≥25.0 kg/m². BMI, body composition, and average daily steps were measured at baseline, 6 weeks, and 12 weeks. Data were analyzed using SPSS version 26.0, and repeated-measures analysis of variance with the paired t-test for post-hoc analysis was conducted. Results: In total, 48 participants in the intervention group and 61 participants in the control group completed the study. A significant interaction was found between time and group. The post-hoc analysis showed a significant difference between pre-intervention and post-intervention (within the intervention group). The post-intervention analysis revealed an increase in the mean number of daily steps by 3571.59, with decreases in body weight (-2.20 kg), BMI (-0.94 kg/m²), body fat percentage (-3.52%), visceral fat percentage (-1.29%) and waist circumference (-2.91 cm). Skeletal muscle percentage also showed a significant increase (1.67%). Conclusions: A 12-week walking program combining a 7000-step goals with weekly group walking activities had a significant effect on the anthropometric measurements of previously inactive and overweight/obese elderly people.

• Journal of Animal Reproduction and Biotechnology
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• v.37 no.4
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• pp.218-225
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• 2022

High levels of proinflammatory cytokines have been observed in obese pregnancies. Obesity during pregnancy may increase the risk of various pregnancyrelated complications, with pathogenesis resulting from excessive inflammation. Palmitic acid (PA) is a saturated fatty acid that circulates in high levels in obese women. In our previous study, we found that PA inhibited the proliferation of trophoblasts developing into the placenta, induced apoptosis, and regulated the number of cleaved halves derived from transfer RNAs (tRNAs). However, it is not known how the expression of tRNA-derived stress-induced RNAs (tiRNAs) changes in response to PA treatment at concentrations that induce inflammation in human trophoblasts. We selected concentrations that did not affect cell viability after dose-dependent treatment of HTR8/SVneo cells, a human trophoblast cell line. PA (200 μM) did not affect the expression of apoptotic proteins in HTR8/SVneo cells. PA significantly increased the expression of inflammatory cytokines including interleukin (IL)-1β, IL-6, IL-8, and tumor necrosis factor (TNF)-α. In addition, 200 μM PA significantly increased the expression of tiRNAs compared to 800 μM PA treatment. These results suggest that PA impairs placental development during early pregnancy by inducing an inflammatory response in human trophoblasts. In addition, this study provides a basis for further research on the association between PA-induced inflammation and tiRNA generation.

• The Research Journal of the Costume Culture
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• v.23 no.4
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• pp.726-736
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• 2015

The apparel industry has recently been recognizing the important target market of middle-aged women. The aim of this study was to examine the anthropometric characteristics of US women of 46 to 65 years of age and identify distinctive body shape characteristics of US middle-aged women. A total of 1915 middle-aged women whose ages ranged from 46 to 65 were selected from the SizeUSA database. The age range was divided into two groups: 46-55 and 56-65. Twenty-four body measurements important for apparel development were chosen. Four factors-Girth Factor, Height Factor, Hip Drop Factor, and Bust Drop Factor-accounted for the US middle-aged women's body measurements. The body shapes were classified into four body shapes, which were Y-Shape in the overweight range, S-Shape in the overweight range, H-Shape in the overweight range, and the A-Shape in obese range. H-Shape, which was the least-defined waist in relation to the bust and hips with a short height, existed more in older middle-aged women than in younger middle-aged women. Y-Shape, S-Shape, and A-Shape existed more in the group of younger middle-aged women than in the group of older middle-aged women. In addition, compared with the younger middle-aged women, older middle-aged women had narrower shoulders, a larger waist, thinner legs, and a longer distance between side neck to bust point. The findings from the current study may be applied in the apparel industry for developing clothing sizing systems for US middle-aged women.

• Journal of the Korean Data and Information Science Society
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• v.24 no.4
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• pp.867-876
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• 2013

Metabolic syndrome has been known as a major factor of cardiovascular disease. Several metabolic disorders, particularly chronic disease is complex, and from individuals that appear in our country, the prevalence of the metabolic syndrome is increasing gradually. Therefore, this study, using a multi-factor dimensionality reduction method, checks the major single risk factor of metabolic syndrome and suggests a new diagnosis results of metabolic syndrome. Data of 3990 adults who responded to all the questionnaires of health interview are used from the database of the 5th Korea national health and nutrition examination survey conducted in 2010. As the result, the most dangerous single risk factor for metabolic syndrome was waist circumference and the most dangerous combination factors were waist circumference, triglyceride, and hypertension. This is the result of a new diagnosis of the metabolic syndrome. Especially, waist circumference, low HDL-cholesterol and hypertension were the most dangerous combination for male. In particular, the combination of waist circumference, triglyceride and diabetes was dangerous for obese people.

• The Journal of Korean Academic Society of Nursing Education
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• v.11 no.2
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• pp.200-205
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• 2005

Purpose: This descriptive study was designed to investigative BMI(body mass index) and health behaviors in college students. Method: The subjects of this study consisted of 189 college women and 125 college men. Data were collected using self-report questionnaires from April 1 to April 10, 2005. Data were analyzed by the SPSS /pc 10.0 statistical program using frequency, t-test, $x^2$-test. Result: College women perceived themselves as more obese than indicated their BMI, and the most effective weight control factor was their response to images of people presented in the media. In general college men present more salubrious behavior than college women. Conclusion: The results suggest that health care providers need to educate female students about heathy behavior as well as the normal weight in BMI.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.6
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• pp.3419-3423
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• 2013

Of all gynecologic cancers, endometrial cancer is the most common cancer in the US and Europe. In addition, it is presently the second most common gynecologic cancer in the world. As a result of increasing menopausal, obese and tamoxifen use women, the incidence of the cancer seems to be on the increase. Surgery is the major treatment, whereas postoperative radiation therapy in high-intermediate risk patients many prevent locoregional recurrence. Adjuvant chemotherapy can improve progression free survival in advanced or recurrent cancers. Molecular targeted therapies are now a focus of attention including anti-vascular endothelial growth factor (VEGF), mammalian target of rapamycin (mTOR) inhibitor and tyrosine kinase inhibitor (TKI). They may provide useful future strategies for control of endometrial malignancies in developing countries and across the world.

• Journal of the Korean Home Economics Association
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• v.43 no.10 s.212
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• pp.155-165
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• 2005

The purpose of this study was to analyze difference in clothing preference based on the perceived body types. The objects of this study were to prepare for the establishment of a marketing strategy and alternative plan intended for users operating in a subdivided market, after analyzing the differences in clothing preference based on the perceived body types. The respondents comprised 192 female adults, who were residents in Busan. The questionnaire was composed of three sections: style, textile, and color of clothing. Data were analyzed by frequency, factor analysis, cluster analysis, discriminate analysis, and ANOVA. Cluster analysis was employed to identify groups of respondents based on the five delineated measure items. Based on the findings, three distinct groups were formed: thin, normal, and obese. The result of this study showed statistically significant differences among the three groups in terms of style, textile, and color of clothing, as well as in terms of demographic characteristics. Marketing and management implications for effectively targeting the segments are discussed.

• Journal of the Korean Society of Costume
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• v.54 no.1
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• pp.37-51
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• 2004

The purpose of this study is to measure middle-aged men's bodies around the ages of thirty-five through fifty-five, whose age-group undergoes drastic changes on their body shapes, and to reveal their physical characteristics by comparing the measurements. Sixty Body measurements were taken on 168 subjects. Statistics analysis of data used Oneway Anova, Correlation, Fator Analysis, Cluster Analysis, Crosstabs. Body shapes are grouped based on the measurements, and TypeI is characterized by small and middle-sized body shapes. Tall and obese body shapes belong to TypeII. Lastly, TypeIII is characterized by body shapes with very tall height and obesity, especially around the abdomen area.