• Title/Summary/Keyword: nutrients analyses

Search Result 134, Processing Time 0.025 seconds

Physiologic and epigenetic effects of nutrients on disease pathways

  • Soo-Hyun Park;Jaein Lee;Jin-Taek Hwang;Min-Yu Chung
    • Nutrition Research and Practice
    • /
    • v.17 no.1
    • /
    • pp.13-31
    • /
    • 2023
  • BACKGROUND/OBJECTIVES: Epigenetic regulation by nutrients can influence the development of specific diseases. This study sought to examine the effect of individual nutrients and nutrient families in the context of preventing chronic metabolic diseases via epigenetic regulation. The inhibition of lipid accumulation and inflammation by nutrients including proteins, lipids, vitamins, and minerals were observed, and histone acetylation by histone acetyltransferase (HAT) was measured. Correlative analyses were also performed. MATERIALS/METHODS: Nutrients were selected according to information from the Korean Ministry of Food and Drug Safety. Selected nutrient functionalities, including the attenuation of fatty acid-induced lipid accumulation and lipopolysaccharide-mediated acute inflammation were evaluated in mouse macrophage Raw264.7 and mouse hepatocyte AML-12 cells. Effects of the selected nutrients on in vitro HAT inhibition were also evaluated. RESULTS: Nitric oxide (NO) production correlated with HAT activity, which was regulated by the amino acids group, suggesting that amino acids potentially contribute to the attenuation of NO production via the inhibition of HAT activity. Unsaturated fatty acids tended to attenuate inflammation by inhibiting NO production, which may be attributable to the inhibition of in vitro HAT activity. In contrast to water-soluble vitamins, the lipid-soluble vitamins significantly decreased NO production. Water- and lipid-soluble vitamins both exhibited significant inhibitory activities against HAT. In addition, calcium and manganese significantly inhibited lipid accumulation, NO production, and HAT activity. CONCLUSIONS: Several candidate nutrients and their family members may have roles in the prevention of diseases, including hepatic steatosis and inflammation-related diseases (i.e., nonalcoholic steatohepatitis) via epigenetic regulation. Further studies are warranted to determine which specific amino acids, unsaturated fatty acids and lipid-soluble vitamins or specific minerals influence the development of steatosis and inflammatory-related diseases.

Biological Assessment of Water Quality by Using Epilithic Diatoms in Major River Systems (Geum, Youngsan, Seomjin River), Korea (돌말(Epilithic Diatom) 지수를 이용한 국내 주요 하천(금강, 영산강, 섬진강)의 생물학적 수질평가)

  • Hwang, Soon-Jin;Kim, Nan-Young;Won, Doo Hee;An, Kwang Kuk;Lee, Jae Kwan;Kim, Chang Soo
    • Journal of Korean Society on Water Environment
    • /
    • v.22 no.5
    • /
    • pp.784-795
    • /
    • 2006
  • The purpose of this study was to assess biological river water quality by using epilithic diatoms at 40 selected sites in Geum, Youngsan, and Seomjin River systems. The sampling and analyses were performed during three seasons including January, April and June in 2005. Various water quality parameters also were analyzed. We attempted to classify the water quality condition by epilithic diatom indices (DAIpo and TDI) with the results of corresponding analyses of various chemical water quality parameters. A five class system was delivered to describe the water quality condition ranged from "very good" to "very poor." We also proposed a way of classifying water quality condition by combining two diatom indices of DAIpo and TDI. Our results showed that biomass of epilithic diatoms varied not only seasonally but spatially; it was not likely that winter diatoms represent average water quality condition, due to high concentration of nutrients. Water quality status assessed by diatom indices was generally worse than that assessed by BOD, indicating that BOD standard likely underestimates the biological condition of the water body. Importantly, nutrient-based diatom index (TDI) generally overestimated organic matter-based index (DAIpo) at most study sites, indicating that diatoms in studied rivers were likely more affected by nutrients than organic matter. Thus, management strategy to improve river water quality in Korea is suggested to emphasize more on the nutrients than organic matters.

The Riboflavin Status in Insulin-Dependent Diabetes Mellitus During Growing Period (성장기 인슐린 의존성 당뇨병 환자의 리보플라빈 영양상태)

  • 이정희
    • Journal of Nutrition and Health
    • /
    • v.27 no.7
    • /
    • pp.729-739
    • /
    • 1994
  • Riboflavin status of 17 insulin-dependent diabetic mellitus(IDDM) patients in growing period was evaluated as a function of energy intake and expenditure, biochemical nutritional status and diabetic control indicators. Compared with recommended dietary allowances for Koreans(RDA, 1989), only 35.3% of subjects was at good levels of all nutrients intakes and 52.9% of subjects was below normal level of height and weight. Nutrients consumed below RDA levels were energy(=88.5% of subjects), niacin(64.7%), iron(52.9%) and protein(23.5%) respectively. The riboflavin status was within normal range by urinary riboflavin excretion but 17.6% of subjects was evaluated as showed riboflavin deficiency by erythrocyte glutathione reductase activity coefficient(EGRAC). Correlation between riboflavin intake, urinary riboflavin excretion, EGRA level and diabetic duration were not statistically significant. Correlation analyses indicated that EGRA level was inversely correlated with thiamin, niacin and cabohydrate intake. No significant correlations were found between the EGRA and glycosylated hemoglobin A1(HbA1) (r=-0.464, p=0.129). From this study, it is suggested that IDDM subjects need to maintain balanced diet containing nutrients above RDA for individual activity during growing period. It needs more study whether the current recommended riboflavin allowance is adequate for diabetic patients.

  • PDF

Nutritional Evaluation of the School Lunch Program : The Nutritent Density and Nutrients that affect the Cost of a Meal (학교급식식단의 영양평가 : 식단의 영양밀도 및 식단가에 영향을 미치는 영양소 연구)

  • 임경숙
    • Journal of Nutrition and Health
    • /
    • v.29 no.10
    • /
    • pp.1132-1141
    • /
    • 1996
  • To provide approprate nutrition informatios and guidelines for the healthy school lunch program(SLP) menus, the nutritional quality of the SLP and the nutrients that affect the food cost of SLP were evaluated after analysis of recipes and food price lists of 776 menus collected from 10 elementary SLP schools in Seoul and Kyunggi province in Korea in the year of 1995. Index of nutritional quality of SLP menus were good enough, showing over 1.0 in all nutrients except vitamin A(0.86) in kyunggi province. The percent of calories from carbohydrates, protein and fat was 52%, 16% and 32%, while the polyunsaturated fatty acid/monousaturate fatty acid/saturated fatty acid(P/M/S) ratio was 1.0/0.95/1.15. On the other hand, the nutrient-cost evaluation showed that the most expersive nutrient for the RDA(Recommended Dietary Allowance) standard of SLP was origined from the cost of energy and vitamin A. In Pertary correlation analyses, the cost of SLP meals was positively asociated with energy(r=0.244, p<0.001), protein(r=0.306, p<0.001) and carbohydrate(r=0.159, p<0.001) in diet, while the most important predictor of the cost of SLP meal provides sufficient nutrients with enough calories, but fat level is somewhat higher than the suggested value from Dietary Guidelines for Koreans. These data also suggest that meals which could offer enough vitamin A might be included in SLP menus and the cost of a SLP meal can be reduced when choosing the cheap protein source food.

  • PDF

Influence of Co-Habitation on a Family Line Resemblance in Nutrient and Food-Group Intake among Three Generations of Japanese Women

  • Sasaki, Satoshi;Tsuji, Tomiko
    • Journal of Community Nutrition
    • /
    • v.5 no.2
    • /
    • pp.93-104
    • /
    • 2003
  • Although a generation-related difference in nutrient and food-group intake has been broadly recognized in the Japanese population, few studies have examined the difference and correlation of intakes with consideration of a family line and co-habitation status. We conducted a dietary survey using female college students in dietetic course in Aichi, Japan, and their mothers and grandmothers. A validated self-administered diet history questionnaire was used for assessment of intakes. Data from 110 families were included in the analysis. The means of 13 nutrients and 10 food groups (of the 15 and 14, respectively) showed significant differences among the three generations. A significant difference was observed in the carbohydrate, protein, saturated fatty acid, cholesterol, and fish intakes between the students living with their mothers and those apart. In the correlation analyses between generations, moderate correlation was observed for most nutrients and food groups between the students and their mothers living together (correlation range = 0.30-0.61 for nutrients, and = 0.21 -0.56 for food groups). A wide variation with no consistency was observed for the correlation between the students and their grandmothers (-0.18 -0.59 and -0.33 -0.65, respectively), No meaningful correlation was observed between any two generations living apart. Among the food groups examined, pulses, fish, and vegetables showed relatively large differences for the correlation between two groups with different living conditions. When living together, the correlation coefficients for nutrients and food groups between the students and their mothers decreased according to the increase in frequency of eating out by the students. These results suggest that living together and eating together were an important factor for the resemblance in dietary habits between generations in the population with a marked generation-related difference in intakes. (J Community Nutrition 5(2) : 93-104, 2003)

Investigation of Hanwoo manure management and estimation of nutrient loading coefficients on land application

  • Won, Seunggun;You, Byung-Gu;Ra, Changsix
    • Journal of Animal Science and Technology
    • /
    • v.57 no.5
    • /
    • pp.20.1-20.8
    • /
    • 2015
  • Background: In order to prepare for the regulation about the limit of manure production, the status of manure management and the amount of nutrients in the compost discharged from Hanwoo breeding farm shall be known. This study aimed to find the practical amount of nutrients (volatile solids, VS; total nitrogen, T-N; total phosphorus, T-P) in manure, and compost samples collected from 40 Hanwoo breeding farms and the loss of the nutrients was calculated during the composting period, which supports to develop nutrient loading coefficients (NLCs) for each nutrient. Results: Although the addition of bedding materials for composting caused the increase of the VS amount before composting, the comparison of VS, N, and P amounts in between manure and compost showed the lower VS by 4 % as well as T-N and T-P amounts by 69 and 40 %, respectively, of which values were corresponded with the NLCs of 0.96, 0.31, and 0.60 for VS, N, and P, respectively, based on the questionnaire, and sample analyses. Considering with the environmental impacts including land application from Hanwoo manure, P loss should be zero before and after composting. In this regard, nitrogen loss of 50 % occurs and VS was increased by 30 %. In addition, feasible cases for the calculations based on the notification from Ministry of Environment were compared with this study. Conclusions: The development of NLCs from Hanwoo manure in this study implies that the loss of nutrients in manure occurs during the composting or storing period. The mass balances of N and P from livestock manure to land application may be overestimated over the practical values. It is necessary to build up the database about each livestock category other than Hanwoo.

Relative Importance of Bottom-up vs. Top-down Controls on Size-structured Phytoplankton Dynamics in a Freshwater Ecosystem: II. Investigation of Controlling Factors using Statistical Modeling Analysis (담수성 식물플랑크톤의 크기별 동태에 대한 상향식, 하향식 조절간의 상대적 중요도 조사: II. 통계 모델링 분석을 이용한 조절인자 분석)

  • Song, Eun-Sook;Lim, Jang-Seob;Chang, Nam-Ik;Sin, Yong-Sik
    • Korean Journal of Ecology and Environment
    • /
    • v.38 no.4 s.114
    • /
    • pp.445-453
    • /
    • 2005
  • Relative importance between bottom-up and top-down controls on phytoplankton dynamics was investigated in the Juam Reservoir, Chonnam based on the results from statistical analyses including regression and artificial neural network (ANN) modeling. Effects of nutrients on size-structured phytoplankton dynamics were explored by simple linear regression analysis and relative importance between bottom-up and top-down controls was estimated based on results from the artificial neural network analyses. Although there is a limitation in determining direct grazing effects since chlorophyll a : pheopigments ratios, indirect index for grazing activity rather than grazing rates or herbivores biomass were used, the results from regression analysis showed that nutrients especially orthophosphates were positively correlated with the phytoplankton biomass and chlorophyll a : pheopigments ratios were also positively correlated with the phytoplankton biomass at lower coefficient of determination ($r^2$) compared to orthophosphates. The simulation results from ANN suggested that the bottom-up mechanisms including water temperature and availability of nutrients, especially orthophosphates were more important than top-down mechanisms such as grazing in the phytoplankton dynamics.

Review of Soil Structure Quantification from Soil Images

  • Chun, Hyen-Chung;Gimenez, Daniel;Yoon, Sung-Won;Park, Chan-Won;Moon, Yong-Hee;Sonn, Yeon-Kyu;Hyun, Byung-Keun
    • Korean Journal of Soil Science and Fertilizer
    • /
    • v.44 no.3
    • /
    • pp.517-526
    • /
    • 2011
  • Soil structure plays an important role in ecological system, since it controls transport and storage of air, gas, nutrients and solutions. The study of soil structure requires an understanding of the interrelations and interactions between the diverse soil components at various levels of organization. Investigations of the spatial distribution of pore/particle arrangements and the geometry of soil pore space can provide important information regarding ecological or crop system. Because of conveniences in image analyses and accuracy, these investigations have been thrived for a long time. Image analyses from soil sections through impregnated blocks of undisturbed soil (2 dimensional image analyses) or from 3 dimensional scanned soils by computer tomography allow quantitative assessment of the pore space. Image analysis techniques can be used to classify pore types and quantify pore structure without inaccurate or hard labor in laboratory. In this paper, the last 50 years of the soil image analyses have been presented and measurements on various soil scales were introduced, as well. In addition to history of image analyses, a couple of examples for soil image analyses were displayed. The discussion was made on the applications of image analyses and techniques to quantify pore/soil structure.