• Journal of Korean Traditional Oncology
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• v.19 no.1
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• pp.61-68
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• 2014

Objectives : To study the effect of SB injection on tumor size in an advanced non-small cell lung cancer patient. Methods : A patient was clinically diagnosed as advanced non-small cell lung cancer (Stage IIIa). Four cycles of intravenous SB injection were conducted. Each cycle lasted 4 days. The content of 7vials SB was injected every day. To compare the tumor size before treatment and after four cycles of SB injection, chest computed tomography (CT) was performed. Results : Follow-up CT images showed that the tumor size was reduced. In admission, size of the tumor $6.7{\times}8.5{\times}9.5cm$ on the left lower lobe of lung. After SB injection, size of the tumor $5.6{\times}6.8{\times}8.4cm$ by Chest CT. The patient's symptoms such as cough, sputum were improving until four cycles of SB injection. Numerical rating scale (NRS) showed improvement of Chest pain from point 3 to point 0. Conclusions : This case study suggests that intravenous SB injection may have significant effects of anti-tumor for non-small cell lung cancer.

• Journal of Oral Medicine and Pain
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• v.40 no.2
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• pp.63-71
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• 2015

Purpose: To investigate the relationship between headache and sleep by evaluating sleep quality, daytime sleepiness, and specific features related to sleep-disordered breathing (SDB). Methods: One hundred one subjects with headache and 118 healthy controls were enrolled. To collect various information on headache attacks, headache group completed self-reported questionnaire about the characteristics of headache attacks and the migraine disability assessment (MIDAS) questionnaire. The subjective quality of sleep was evaluated in all of the subjects using the Pittsburgh sleep quality index (PSQI) and Epworth sleepiness scale (ESS). In addition, the following specific features of sleep were evaluated in 28 subjects selected randomly from each group: apnea-hypopnea index (AHI), prevalence of SDB, nocturnal oxygen saturation (SaO2), and oxygen desaturation index (ODI) as measured using a portable monitoring device. Results: The global PSQI and the prevalence of poor sleeping (global PSQI >5), ESS scores and the prevalence of daytime sleepiness (ESS score >10) were significantly higher in the headache group (both p<0.0001, respectively). The mean scores on the numerical rating scale and the MIDAS were significantly higher in the poor-sleeper group than in the good-sleeper group (p=0.0347 and p=0.0016, respectively). The global PQSI and prevalence of daytime sleepiness were significantly higher in the chronic-headache group than in the acute-headache group (p=0.0003 and p=0.0312, respectively). Conclusions: There is a significant association between headache and sleep. Especially, severity and chronicity of headache were significantly associated with sleep quality and daytime sleepiness.

• Journal of Oral Medicine and Pain
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• v.39 no.3
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• pp.96-99
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• 2014

Purpose: The objective of this retrospective pilot study was to evaluate the effectiveness of Gabapentin in patients with primary burning mouth syndrome (BMS). Methods: Ten subjects were diagnosed with primary BMS (8 women and 2 men). The mean age was 60.1 years. They had clinical examination to exclude local factors such as the presence of Candida species, xerostomia, lichen planus, etc. They also underwent hematological examination to exclude secondary BMS due to systemic disorders. Pain was assessed by patients on an 11-point numerical rating score system (0 to 10). Gabapentin was administered at a starting dose of 300 mg/day, slowly titrated up to maximum of 1,800 mg/day. All patients were treated for 4 weeks. Results: One half of the patients (n=5) obtained reduction in pain over the treatment period. Four patients reported no reduction in pain symptoms. One patient reported that symptoms were worsening. The average pain score before the treatment was 6.3 and after the treatment was 5.25. No significant relationship was detected between pretreatment and posttreatment pain score. Only one patient noted mild side effect (dizziness). Conclusions: This retrospective pilot study provides no preliminary evidence that Gabapentin has effect in the management of BMS. However, further research (well-designed, randomized, and controlled trial with large sample) would be needed to investigate the efficacy of Gabapentin in treatment of BMS.

• Journal of Oral Medicine and Pain
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• v.44 no.4
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• pp.160-168
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• 2019

Purpose: To search the salivary factors that objectively indicate an pain in myalgia patients with temporomandibular joint disorder (TMD) and determine the possibility of the factors as pain-biomarkers. Methods: Participants consisted of pain-free 15 persons (male 7, female 8, mean age±standard deviation (SD); 26.8±16.04 years) and 45 myalgia patients with TMD (male 21, female 24, mean age±SD; 27.98±13.01 years). They were divided into a pain-free group (numerical rating scale [NRS] score 0), a mild pain group (NRS 1-4), a moderate pain group (NRS 5-6), and a severe pain group (NRS 7-10) and members of all groups were age, sex matched. Interleukin-8 (IL-8) and matrix metalloprotease 9 (MMP-9) were selected as pain biomarkers, by searching the Gene Expression Omnibus database and analyzing pain-related genes. Enzyme-linked immunosorbent assays were used to measure the concentration of IL-8 and MMP-9 in the patients' saliva. Results: IL-8 and MMP-9 levels were statistically significantly higher in pain groups than in the pain-free group. Greater differences were observed in patients with acute pain (with painful duration under 3 months) than in the control group and in female patients than in male. Conclusions: Salivary IL-8 and MMP-9 may play a role as biomarkers of myalgia in patients with TMD.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2002.11a
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• pp.139-145
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• 2002

The flow zone through propeller jets are used in evaluating the environmental and constructional effects of navigation on the waterway. It relies on the characteristics of ships and water depth. A numerical model using the momentum theory of the propeller and Shield's diagram was developed in a restricted waterway. Equations for discharge are presented based on thrust coefficients and propeller speed and are the most accurate means of defining discharge. Approximate methods for discharge are developed based on applied ship's power. Equations for discharge are as a function of applied power, propeller diameter, and ship speed. Water depth of the waterway and draft of the shop are also necessary for the calculation of the grain size of the initial motion. The velocity distribution of discharge from the propeller was simulated by the Gaussian normal distribution function. The shear velocity and shear stress were from the Sternberg's formula. Case studies to show the influence of significant factors on sediment movement induced by the ship's propeller at the channel bottom are presented.

• Journal of Navigation and Port Research
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• v.31 no.5 s.121
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• pp.361-368
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• 2007

The storage space requirement is a very important decision variable which determines the storage capacity of a container terminal. Generally, the storage space requirement is dependent upon such factors as ship headway, allowable dwell time of containers, loading/winding time per ship, and so on. Until now, the storage space requirement is estimated under the assumption that the factors are deterministic in several studies. However, this study proposes how to estimate a storage space requirement satisfying the required service level under the assumption that a containership's load size is probabilistic. Numerical experiments, which use a simulation show that the proposed method can estimate more adequately the storage space requirement than other methods under a probabilistic environment.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2013.05a
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• pp.500-502
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• 2013

The metallic underground pipes like as metropolitan water supply pipes and gas pipes have a screening effects for power induction phenomenon. Generally, urban area has more metallic underground facilities than rural areas because of its buildings or population density. So we can expect high screening effects for the power induction in urban areas, and we call it the city screening factor. We had carried out the measuring test in urban and rural area respectively 30 sites to prove the actual effects of city screening factor and we derived the numerical value of city screening effects. But we faced with a difficult question that how we can classify the real urban areas or rural areas correctly. In this paper, we introduce the classification method using density of building in test area to apply the city screening factor reasonably.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.37 no.7A
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• pp.512-521
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• 2012

In this paper, we propose feasible combining rules for a decoding scheme of product codes to apply finite soft decision. Since the decoding scheme of product codes are based on complex tanh calculation with infinite soft decision, it requires high decoding complexity and is hard to practically implement. Thus, simple methods to construct look-up tables for finite soft decision are derived by analyzing the operations of the scheme. Moreover, we focus on using convolutional codes, which is popular for easy application of finite soft decision, as the horizontal codes of product codes so that the proposed decoding scheme can be properly implemented. Numerical results show that the performance of the product codes with convolutional codes using 4-bit soft decision approaches to that of same codes using infinite soft decision.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.3
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• pp.453-459
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• 2020

It is important to increase the probability that all developed weapon systems can be operated in a steady state at any time. In the case of Integrated Logistics Support, this probability is referred to as operational availability, and the numerical value is quantified during the development process. There are several ways to improve operational availability for successful development of weapon systems. One of the methods is to reduce total corrective maintenance time through Automatic Test Equipment(ATE). Recently, customers in the defense market have become aware of this and demand ways to improve operational availability of weapon systems. Therefore, this paper proposes ways to improve operational availability of weapon systems by changing the method of operating the ATE. The detailed method is to allow field maintenance personnel to carry out field maintenance support onsite. This is an effective way to reduce the total corrective maintenance time of weapon systems by reducing the travel time of field maintenance personnel. The proposed ATE is proved to be able to achieve superior maintenance and operational availability.

• Journal of the Korean Institute of Intelligent Systems
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• v.21 no.2
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• pp.268-275
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• 2011

This paper proposes two optimal path planning methods of a mobile robot using uDEAS (univariate Dynamic Encoding Algorithm for Searches). Before start of autonomous traveling, a self-controlled mobile robot must generate an optimal global path as soon as possible. To this end, numerical optimization method is applied to real time path generation of a mobile robot with an obstacle avoidance scheme and the basic path generation method based on the concept of knot and node points between start and goal points. The first improvement in the present work is to generate diagonal paths using three node points in the basic path. The second innovation is to make a smooth path plotted with the blending polynomial using uDEAS. Effectiveness of the proposed schemes are validated for several environments through simulation.