• 대한임상검사과학회지
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• 제44권3호
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• pp.147-154
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• 2012

Metabolic syndrome and homocysteine are associated with increased independent risk factors of cardiovascular disease. We investigated the difference between the degree of obesity, metabolic syndrome risk factors, plasma homocysteine and anthropometric obesity factors. Totally 398 participated in a medical check-up program were selected for this study. Subjects were categorized into three groups according to the number of metabolic syndrome components present as defined by the NCEP-ATP III criteria; Absent (0 criteria, n=124), Pre-MetS (1-2 criteria, n=220) and MetS (${\geq}3$ criteria, n=54). Body mass index (BMI) is a measure used to distinguish between normal weight, overweight and obesity. MetS presented higher homocysteine than Absent (p<.05) and obesity higher than normal weight (p<.01). When Absent+Pre-MetS was used to classify obese or not, obesty presented higher homocysteine than non-obese (p<.05). Further homocysteine levels positively correlated with weight, BMI, waist circumference, hip circumference and waist-hip ratio (WHR). Especially WHR is not only MetS (r=0.378, p<.001) but also Absent+Pre-MetS (r=0.305, p=0.029) significantly positively correlated with homocysteine. The results of our study indicate that homocysteine is related closely to obesity. Although obesity has not been diagnosed with metabolic syndrome, obesity related with increased homocysteine.

• 대한디지털의료영상학회논문지
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• 제10권1호
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• pp.51-58
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• 2008

Obesity which causing many physical and psychological problems is difficult to treatment. The purpose study was investigate relationships between weight, height, body mass index (BMI) and BMD of according to the low, normal, over, obesity, high group. According to obesity index, each group was divided into five proup. Study subjects were man(n=135) and woman(n=145). We checked the BMD of femoral neck and lumbar spine by using dual energy X-ray bone densitometry. Weight was positively correlation with height (p<0.05) by Pearson's correlation matrix. There was a significant difference in BMD of femoral neck and lumbar spine between four(low, normal, over, obesity) groups except for high obesity groul.

• 한국학교보건학회지
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• 제13권1호
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• pp.97-108
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• 2000

This study researches an obesity index and the realities of physical activity of elementary school children and provide basic data to instruct correct physical activity for low weight and obese children. The subject was 813 Elementary School Children of grade 4-6 in Kyungju and data were collected with a Physical Activity Questionnaire from YHS, USA. The collected data were analyzed with real number, percentage, average and standard deviation techniques. The range was by SPSS WIN. Both of them were in the normal range, between -38.3 and 77.7, between low weight and obesity. The results are as follows : 1. An Obesity index according to grade and sex: the average obesity index of 423 boys was $7.56{\pm}15.7$, for girls it was $2.56{\pm}14.3$. Both of them were in the normal range, between -38.3 and 77.7. There were low weight($-38.85{\pm}0.9$) students as well as obese, including extremely low weight children ($-38.85{\pm}0.9$) and extremely obese children. 2. On the whole, in the Frequency of the 25 item physical activities breakdown, children reported to watch TV 1. ($2.7{\pm}0.6$), or do homework($2.1{\pm}0.9$), more than three-fourths of the week, male children, however, played more football($2.0{\pm}0.9$). As male obese children do less MET5, MET8(highly active activity) than male normal children, it was also discovered that low weight children do more severe activity in MET8(high activity). In female cases, it was revealed that neither do highly intense activity. 3. In physical activity, male children received higher points than female children with $92.94{\pm}37.95$ to $74.46{\pm}29.50$. On the whole, male and female obese children had lower score than normal children. 4. As for attitude toward physical activity, male children($31.96{\pm}4.37$) had a positive attitude than female children ($29.57{\pm}3.89$), but obese male children had a negative attitude regarding activity viewed as normal. Therefore, in preventing obesity in elementary school children the treating of under-weight children should be included in the obesity program so as to prevent mal-nutrition or deficiency. It is needed to instruct obese children to carry out intensive work-outs at least 3 times a week through systematic programs. It is also needed that parents and teachers educate elementary school children from an early age with information on the frequency and intensity of work-outs to prevent obesity. It is also desirable that children be educated to carry out physical activities that address their specific needs. As a result of this study, obesity management must be started from elementary school and children should be instructed to act in high-intensity actirities when they spend leisure time.

• 대한지역사회영양학회지
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• 제13권3호
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• pp.334-345
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• 2008

The purpose of this study was to compare nutrient intakes and blood lipids according to the obesity index of middle aged men. Subjects were assigned to one of the following groups based on percentage of body fat (%Fat),; normal weight (10-20% fat), overweight (20-25% fat) and obesity (over 25% fat). Nutrient intakes were evaluated based on questionnaires and 24 hour recall method and blood lipids were analyzed by blood analyzer. The results were as follows: 1) Nutrient intakes were that carbohydrate intake rate in obesity group was lower than normal group and lipids intake rate in obesity group was higher than normal group. The intake of riboflavin and folic acid were differ normal and obesity group (p < 0.05), and normal group ingested under recommended intake. 2) Total-cholesterol, LDL-cholesterol and blood pressure in obesity group were higher than normal group but the differences were not significant. The attack rate of coronary heart disease and blood glucose in obesity group is higher than normal group (p < 0.05). 3) The correlation of anthropometric measurements, blood lipid, blood glucose and blood pressure had significant results. Soft lean mass was associated BMI (p < 0.01), TC (p < 0.05), HDL (p < 0.05), LDL (p < 0.05) and SBP (p < 0.05). TG was associated TC (p < 0.05), HDL (p < 0.01), VLDL (p < 0.001) and Risk (p < 0.01). TC was associated LDL (p < 0.01) and Risk (p < 0.01). Blood glucose was associated TC (p < 0.05), LDL (p < 0.05), SBP (p < 0.05) and DBP (p < 0.05). These results suggest that reduction of body weight for the attack risk of obesity group in coronary heart disease.

• 대한지역사회영양학회지
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• 제29권3호
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• pp.212-221
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• 2024

Objectives: Metabolic disease is strongly associated with future insulin resistance, and its prevalence is increasing worldwide. Thus, identifying early biomarkers of metabolic-related disease based on serum profiling is useful to control future metabolic disease. Our study aimed to assess the association of serum branched chain amino acids (BCAAs) and aromatic amino acids (AAAs) ratio and metabolic disease according to body mass index (BMI) status among Korean adults. Methods: This cross-sectional study included 78 adults aged 20-59 years in Korea. We compared serum amino acid (AA) levels between adults with normal-weight and adults with obesity and investigated biomarkers of metabolic disease. We examined serum AA levels, blood profile, and body composition. We also evaluated the association between serum AAs and metabolic-related disease. Results: The height, weight, BMI, waist circumference, hip circumference, waist-hip-ratio, body fat mass, body fat percent, skeletal muscle mass, systolic blood pressure, and diastolic blood pressure were higher in the group with obesity compared to normal weight group. The group with obesity showed significantly higher levels of BCAA, AAA, and BCAA and AAA ratio. Further, BCAA and AAA ratio were significantly positively correlated with triglyceride, body weight, and skeletal muscle mass. The evaluation of metabolic disease risks revealed an association between the ratios of BCAAs and AAAs, hypertension, and metabolic syndrome. Conclusions: Our study is showed the associations between BCAA and AAA ratio, obesity, and obesity-related diseases using various analytical approaches. The elevated BCAA and AAA ratio could be early biomarkers for predicting future metabolic diseases in Korean population.

• 비만대사연구학술지
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• 제3권1호
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• pp.27-34
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• 2024

The prevalence of obesity in children and adolescents is increasing worldwide. Obesity in children and adolescents not only increases the risk of transitioning to obesity in adulthood but also increases the risk of cardiometabolic diseases such as high blood glucose, high blood pressure, dyslipidemia, fatty liver, and hyperinsulinemia during childhood. The goal of treating obesity in children and adolescents is not to focus on weight loss but to help children reach a healthy weight while maintaining normal growth appropriate for their age and sex. To achieve this goal, regular physical activity and exercise, dietary modification, improvement of obesity-prone environmental factors, and behavioral changes are required for a healthy lifestyle. If appropriate weight control is not achieved through lifestyle modifications, pharmacotherapy may be considered for adolescents with severe obesity aged 12 and above. Recent clinical trials have reported the efficacy and safety of pharmacotherapy in severely obese adolescents. Currently, two medications can be prescribed in Korea for patients with obesity aged 12 and above: Orlistat and Liraglutide. However, despite effective weight control through drug treatment, body weight may increase again after treatment discontinuation. Therefore, it is crucial to evaluate adherence to health behaviors during visits and continue to educate on lifestyle modifications, even during pharmacotherapy, to minimize weight regain.

• 한국농촌간호학회지
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• 제7권2호
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• pp.51-58
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• 2012

Purpose: to investigate the relationship of between socioeconomic characteristics, and weight perception and lifestyle on body mass index (BMI) in Korea. Method: Participants were 2,405 people recruited from the 2007 Fourth Korea National Health and Nutrition Examination Surveys. Data included weight perception, BMI, and lifestyle factors and was analyzed using ${\chi}$ 2-test, logistic regression Results: Perception of weight was significantly different according to gender, age, education and residence. In the obesity group 21.6% perceived their weight as normal whereas 29.6% of the normal group perceived their weight as obese. In the obesity group, men who were over 70 years old, rural residents and only had elementary education perceived their weight range as normal. In the normal weight group, women who were urban residents and university graduates more frequently perceived their weight as obese. Logistic regression analysis of lifestyle factors, indicated that misperceived obesity was associated with walking (OR=0.703, 95% CI=0.553-0.896), weight control (OR=2.693, 95% CI=2.080-3.485), and health exam (OR=0.730, 95% CI=0.567-0.940) whereas misperceived normal weight was associated with walking (OR=0.696, 95% CI=0.497-0.975), weight control (OR=0.523, 95% CI=0.363-0.749). Conclusion: Results indicate differences in self-perceived weight and life style and provide information that can be used for health promotion program development.

• 대한영양사협회학술지
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• 제6권1호
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• pp.44-52
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• 2000

Two hundred sixty six children were retrospectively surveyed from first to fifth grade to find out the status of obesity during four years. The obesity index was gained by height and weight data from student's health file and the data about eating behaviors and weight control behaviors, etc. were collected by questionnaires. Children assigned to one of the following groups : underweight, normal, overweight and obese. The results were as follows ; 1. Obese children were 18.6%(n=27) of boys and 10.8%(n=13) of girls at fifth grade. 2. Twenty eight children among forty obese children at fifth grade were also overweight or obese at first grade, and the other twelve was normal. 3. Breakfast skipping rate was significantly high among underweight and obese group of boys(p<0.01).The most children(87.6%) had prejudice for special foods. 4. The rate of agreement between obesity index and self recognition of body image was 60.7% in boys and 63.6% in girls. 5. Forty two point five percent of children have ever tried weight control as exercise(35.7%), reducing sugars and snacks(27%), fasting(23.8%), avoiding fatty foods(12.7%), taking diet food or drug(0.8%). In conclusion, the prevalence of children obesity is gradually increasing and children tried weight control without right guidances. In order to prevent progress into adulthood obesity, nutrition education should be followed with school foodservice including the right perception for obesity, proper weight control and eating behavior modification.

• 대한지역사회영양학회지
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• 제16권6호
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• pp.706-715
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• 2011

This study aims to identify the dietary patterns relevant to obesity of Korean women among low income classes. Adults 20-64 years were used as study subjects from the data of 2005 Korea National Health and Nutrition Examination Survey. We compared obese and normal-weight women in terms of their nutrients intake, diet quality and food patterns. Diet quality was assessed by using the Nutritional Adequacy Ratio (NAR) and Index of Nutritional Quality (INQ). Our results showed higher prevalence of obesity among lower socioeconomic status women. In men, there were no significant associations with socioeconomic status and prevalence of obesity. Higher risk of nutritional inadequacy was observed among obese women compared to normal weight women. Obese women showed significantly lower INQ for nutrients such as Ca, Fe, Vitamin A, Thiamin, Riboflavin and Vitamin C compared to other women. They consumed significantly higher amount of rice (p < 0.05) and lower amount of vegetables (p < 0.01). By contrast, obese men from low income classes showed higher intake of those nutrients. Obese men also consumed significantly higher amount of meats than normal weight men. Therefore, this study suggests that gender-specific approaches based on economic situation should be considered in developing the intervention program for managing obesity for low income classes.

• Toxicological Research
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• 제22권4호
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• pp.339-348
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• 2006

Misaengtang (MST), a formula of Korean herbal medicines, has been used as a weight-controlling recipe. We have investigated two experiment of body weight regulation by MST In rats. i) The anti-obesity effect of MTS on a high fat diet-induced obesity, male Sprague-Dawley rats were fed with a high-fat diet containing 30% in the absence or presence of MST (0.3, 1 or 3%) or a reference orlistat (0.05%) for 6 weeks. ii) weight-decrease effect of MST on normal diet, same animal were fed with a normal diet in the absence or presence of MST (3%) for 6 weeks. And the body weights, daily feed and water consumptions, organ weights, fat weights serum biochemistry were measured. In both experiments, MST and orlistat did not affect the body weight gain. But orlistat significantly increased the feed and water consumptions, leading to low-feed efficiency, and orlistat markedly reduced abdominal, paratesticular and perirenal fat weights, although increased the kidney weights. In MST, low dose (0.3%) of MST decreased the perirenal fat and increased the kidney weights in rats fed HFD, and MST 3% decreased the abdominal fat weights in rats fed normal diet. In addition, Orlistat caused changes in parameters of hepatotoxicity (AST and glucose), nephrotoxicity (BUN and B/C ratio) and lipid metabolism (HDL and triglycerides). In comparison, MST decreased AST, ALP and ALT, the hepatotoxicity markers, and somewhat improved the hepatic fatty degeneration. Taken together, it is suggested that MST does not exert anti-obesity activity as well as remarkably direct effects, but MST may be potentially benefit for dietary cure and exercise-cure of obesity.