• Bulletin of the Korean Chemical Society
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• v.23 no.8
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• pp.1139-1143
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• 2002

Analysis of lysophosphatidic acids (LPAs) is of clinical importance as they can serve a potential marker for ovarian and other gynecological cancers and obesity. It is critically important to develop a highly sensitive and specific method for the early detection of gynecological cancers to improve the overall outcome of this disease. We have established a novel quantification method of LPAs in human plasma by negative ionization tandem mass spectrometry (MS-MS) using multiple reaction monitoring (MRM) mode without the conventional TLC step. Protein-bound lipids, LPAs in plasma were extracted with methanol : chloroform (2:1) containing LPA C14:0 as an internal standard under acidic condition. Following back extraction with chloroform and water, the centrifuged lower phase was evaporated and reconstituted in methanol. The reconstituted solution was directly injected into electrospray source of MS/MS. For MRM mode, Q1 ions selected were m/z 409, 433, 435, 437 and 457 which corresponds to molecular mass [M-H]- of C16:0, C18:2, C18:1, C18:0 and C20:4 LPA, respectively. Q2 ions selected for MRM were m/z 79, phosphoryl product. Using MS/MS with MRM mode, all the species of LPAs were completely separated from plasma matrix without severe interferences. This method allowed simultaneous detection and quantification of different species of LPAs in a plasma over a linear dynamic range of 0.01-25 ㎛olL-1 . The detection limit of the method was 0.3 pmol/mL, with a correlation coefficient of 0.9983 in most LPAs analyzed. When applied to the plasmas of normal and gynecological cancer patients, this new method differentiated two different groups by way of total LPA level.

• 유체기계공업학회:학술대회논문집
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• 2006.08a
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• pp.269-272
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• 2006

The heat and smoke which generated by subway under fire is one of the most harmful factor in air tighten underground station. To prevent this, Trackway Exhaust System(TES) can be used. The heat released from the train running in the tunnel raises the temperature at the platform and the trackway, and thus proper ventilation system is required for comfortable underground environment. When the fire is occurred, TES is operated as smoke exhaust mode from normal ventilation mode. In the present study, the subway station which is one of the line number 9 in Seoul subway is modeled, and fired situation is simulated with several ventilation mode of ventilation system in trackway. For this simulation whole station is modeled. Non steady state 3D simulation which considered train under fire is entering to the station is performed. Temperature and smoke distribution in platform and trackway are compared. To represent heat by fire, heat flux was given to the fired carriage, also to describe smoke by fire, concentration of CO is represented. As the result of present study, temperature and smoke distribution is different as the method of ventilation in trackway and platform is changed. In over side of trackway, the fan must be operated as exhaust mode for efficient elimination of heat and smoke, and supply mode of fan operation in under side shows better distribution of heat and smoke. The ventilation system which is changed from ventilation mode to exhaust mode can be applied to control heat and smoke under fire.

• Journal of Multimedia Information System
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• v.1 no.2
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• pp.127-132
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• 2014

The transverse electromagnetic (TEM) cells are widely used for electromagnetic compatibility (EMC) testing and field probe calibrations. We propose the verification of TEM mode with statistical method using a four-port TEM cell. The verification results are compared with Normal, Rayleigh, and Gamma distribution. As a result, the 75 % quantile of the Rayleigh distribution is excellent agreement with the true quantiles for a number of calibration points.

• Proceedings of the Korea Concrete Institute Conference
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• 1998.10b
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• pp.839-844
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• 1998

The purpose of this study is to analyze the interface debonding failure on RC beams strengthened with carbon fiber sheet(CFS). The behavior of damaged RC beams strengthened with CFS is analytically investigated using both linear elastic fracture mechanics (LEFM) approach and the finite element method. This study includes the investigation of the separation mode by interface fracture of the strengthening materials due to the interfacial shear and normal stresses.

• Structural Engineering and Mechanics
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• v.8 no.2
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• pp.193-205
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• 1999

A formulation for the dynamic stability analysis of cylindrical shells resting on elastic foundations is presented. In this previously not studied problem, a normal-mode expansion of the partial differential equations of motion, which includes the effects of the foundation as well as a harmonic axial loading, yields a system of Mathieu-Hill equations the stability of which is analyzed using Bolotin's method. The present study examines the effects of the elastic foundation on the instability regions of the cylindrical shell for the transverse, longitudinal and circumferential modes.

• Proceedings of the KSME Conference
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• 2008.11b
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• pp.2946-2951
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• 2008

Combustion instability is a major issue in design of gas turbine combustors for efficient operation with low emissions. Combustion instability is induced by the interaction of the unsteady heat release of the combustion process and the change in the acoustic pressure in the combustion chamber. In an effort to develop a technique to predict self-excited combustion instability of gas turbine combustors, a new stability analysis method based on the transfer matrix method is developed. The method views the combustion system as a one-dimensional acoustic system with a side branch and describes the heat source as the input to the system. This approach makes it possible to use the advantages of not only the transfer matrix method but also well-established classic control theories. The approach is applied to a simple gas turbine combustion system to demonstrate the validity and effectiveness of the approach.

• Computers and Concrete
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• v.2 no.2
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• pp.125-146
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• 2005

The objective of this paper is setting out, for a cable-stayed bridge with a curtain suspension, a method to determine the modes of vibration of the structure. The system of differential equations governing the vibrations of the bridge, derived by means of a variational formulation in a nonlinear field, is reported in Appendix C. The whole analysis results from the application of Hamilton's principle, using the expressions of potential and kinetic energies and of the virtual work made by viscous damping forces of the various parts of the bridge (Monaco and Fiore 2003). This paper focuses on the equation concerning the transversal motion of the girder of the cable-stayed bridge and in particular on its final form obtained, restrictedly to the linear case, neglecting some quantities affecting the solution in a non-remarkable way. In the hypotheses of normal mode of vibration and of steady-state, we propose the resolution of this equation by a particular method based on a numerical approach. Respecting the boundary conditions, we derive, for each mode of vibration, the corresponding frequency, both natural and damped, the shape-function of the girder axis and the exponential function governing the variability of motion amplitude in time. Finally the results so obtained are compared with those deriving from the dynamic analysis performed by a finite elements calculation program.

• Proceedings of the KIPE Conference
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• 2013.11a
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• pp.11-12
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• 2013

In this research, a novel multi-converter system for the fuel cell diagnostics and the load leveling function under varying load condition is proposed. The proposed system is composed of two converters and operates in two different modes. In the normal mode operation the additional bidirectional converter is used for the load leveling and in the diagnostic mode it is used for implementing integral diagnostics by way of electrochemical impedance spectroscopy (EIS). The proposed method can perform the EIS for fuel cell under varying load conditions with no influence to the load. The validity and feasibility of the proposed system is verified by the experiments and the design procedure of the proposed system is detailed.

• Journal of the Korean Society for Nondestructive Testing
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• v.29 no.6
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• pp.586-590
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• 2009

Poisson's ratio, one of elastic constants of elastic solids, has not attracted attention due to its narrow range and difficult measurement. Transverse wave velocity as well as longitudinal wave velocity should be measured for nondestructive measurement of Poisson's ratio. Rigid couplants for transverse wave is one of obstacle for scanning over specimen. In the present work, a novel measurement of Poisson's ratio distribution was applied. Immersion method was employed for the scanning over the specimen. Echo signals of normal beam longitudinal wave were collected, and transverse wave modes generated by mode conversion were identified. From transit time of longitudinal and transverse waves, Poisson's ratio was determined without the information of specimen thickness. Poisson's ratio distribution of the carbon steel weldment was mapped. Heat affected zone of the weldment was clearly distinguished from base and filler metals.

• Journal of the Korean Society for Nondestructive Testing
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• v.28 no.6
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• pp.519-523
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• 2008

Poisson's ratio is one of elastic constants of elastic solids. However, it has not attracted attention due to its narrow range and difficult measurement. Transverse wave velocity as well as longitudinal wave velocity should be measured for nondestructive measurement of Poisson's ratio. Hard couplant for transverse wave prevents transducer from scanning over specimen. In the present work, a novel measurement of Poisson's ratio distribution was proposed. Immersion method was employed for the scanning over the specimen. Echo signals of normal beam longitudinal wave were collected. Transverse wave modes generated by mode conversion were identified. From transit time of longitudinal and transverse waves, Poisson's ratio can be determined without information of specimen thickness. This technique was demonstrated for aluminum and steel specimens.