• Nuclear Engineering and Technology
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• 제50권2호
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• pp.246-252
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• 2018

A series of simulated reactivity-initiated accident (RIA) tests on irradiated fully recrystallized boiling water reactor Zircaloy-2 cladding has been performed by means of the expansion-due-to-compression (EDC) test method. The EDC method reproduces fuel pellet-clad mechanical interaction (PCMI) conditions for the cladding during RIA transients with respect to temperature and loading rates by out-of-pile mechanical testing. The tested materials had a large variation in burnup and hydrogen content (up to 907 wppm). The results of the EDC tests showed variation in the PCMI resistance of claddings with similar burnup and hydrogen content, making it difficult to clearly identify ductile-to-brittle transition temperatures. The EDC-tested samples of the present and previous work were investigated by light optical and scanning electron microscopy to study the influence of factors such as azimuthal variation of the Zr-hydrides and the presence of hydride rims and radially oriented hydrides. Two main characteristics were identified in samples with low ductility with respect to hydrogen content and test temperature: hydride rims and radial hydrides at the cladding outer surface. Crack propagation and failure modes were also studied, showing two general modes of crack propagation depending on distribution and amount of radially oriented hydrides. It was concluded that the PCMI resistance of irradiated cladding under normal conditions with homogenously distributed circumferential hydrides is high, with good margin to the RIA failure limits. To further improve safety, focus should be on conditions causing nonfavorable hydride distribution, such as hydride reorientation and formation of hydride blisters at the cladding outer surface.

• Journal of Chest Surgery
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• 제21권4호
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• pp.672-680
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• 1988

Munro is generally considered the first person to have demonstrated, in 1888, in an infant cadaver, the feasibility of dissection and ligation of a persistently patent ductus arteriosus. In august, 1938, Robert Gross reported first successful division and suture of the patent ductus of 7 year old girl. Interruption of a ductus is one of the most satisfactory and curative operations in the field of surgery for congenital heart disease. Seventy-eight consecutive cases of closure of patent ductus arteriosus were operated from June 1980 to June 1988 in the department of thoracic and cardiovascular surgery in Maryknoll Hospital. Retrospective clinical analysis of the patients were 1. There were 24 males, 54 females. 2. The age range of the patients were from 7 months to 32 years with the mean age 9.8 years. 3. Chief complaints of the patients were frequent URI[70.5%], dyspnea on exertion[36.9%], palpitation[10.3%], but 15 patients[19.2%] had no subjective symptoms. 4. Continuous machinery murmur could be heard at the 2nd or 3rd intercostal space on the left sternal border in 66 patients[84.6%]. The other 12 patients made systolic murmur. 5. Radiographic findings of the Chest P-A were cardiac enlargement in 55 patients[70%], enlargement of pulmonary conus and/or increasing density of pulmonary vascularity in 68 patients[87%]. 6. Electrocardiographic findings of the patients were within normal limit in 23 patients[36%], LVH in 38 patients[48.7%], RVH in 7 patients[9%], biventricular hypertrophy in 5 patients[6%]. 7. Cardiac catheterization performed in 62 patients. Mean Qp/Qs=2.5, mean pulmonary arterial pressure=45 mmHg. 8. 73 patients were operated through left posterolateral thoracotomy: Closure of the ductus by ligation in 64 cases, division with suture in 6 cases, and division with aortopatch in 3 cases. Ligation through median sternotomy under cardiopulmonary bypass were 5 cases. 9. There was no death associated with operation, but one case was experienced with intraoperative tearing of ductus resulting in massive bleeding. The other complications were transient hoarseness in 2 patients, chylothorax in 2 patients.

• International Journal of Industrial Entomology and Biomaterials
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• 제9권2호
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• pp.235-239
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• 2004

Drosophila melanogaster heat shock protein 70 gene promoter (Dhsp70p) is widely used in transgenic insect to drive exogenous gene, and the homologous region 3 from Bombyx mori nucleopolyhedrovirus (BmNPVhr3) functions as an enhancer for several promoters. To test whether BmNPVhr3 can enhance the Dhsp70ps transcriptional activity, the reporter plasmids, which contain the Dhsp70p, the reporter $\beta$-galactosidase gene with SV40 terminator and BmNPVhr3 fragment, are constructed and transfected into the insect cell lines (Bm-N cells and Sf-21 cells) by lipofectin-mediated method. The results from the transient expression assay show that BmNPVhr3 significantly increases transcriptional activity of Dhsp70p both under the normal condition and under the heat-shock treatment, although the effects are significantly different between in Bm-N cells and in sf-21 cells. The enhancing behavior of BmNPVhr3 on the Dhsp70p is in an orientation-independent manner. Meanwhile, the effects of heat-shock treatment on Dhsp70p alone or Dhsp70p/BmNPVhr3 combination present no significant difference, indicating that BmNPVhr3 only enhances the transcriptional activity of Dhsp70p, but cant alter its characteristic of the response to the heat-shock stress. The above results suggest that the Dhsp70p/BmNPVhr3 combination is more effective one to drive exogenous gene for transgene or stable cell expression system in insects.

• 한국수자원학회논문집
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• 제31권3호
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• pp.347-360
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• 1998

균열 암반 매질에서의 지하수 흐름과 오염물질 이송에 대한 수치모의 실험이 hydromechanic 모형과 추계적 그리고 이산적 3차원 균열망 모형에 바탕을 둔 비정상상태 흐름 수치 모형을 이용하여 수행되었다. 오염물질 이송에 대한 수치모의 실험에서 random walk의 일종인 particle following 알고리즘이 사용되었다. 이 연구의 목적은 지하 깊은 곳에 위치한 Hot dry rock에서의 지열 개발을 위해 프랑스 Soultz sous Foret 지역에 설치된 두개의 깊은 착정인 GPK1과 GPK2 사이에서의 tracer test 반응을 1995년에 실행된 유체순환 현장 실험으로 부터 얻어진 자료를 이용하여 예측하는 것이다. 모의 실험 결과 비반응입자(nonreactive particles)에 대한 평균 이송시간은 두 착정 사이에서 약 5일이었다.

• 대한기계학회논문집A
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• 제36권9호
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• pp.1103-1108
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• 2012

주증기관은 보일러와 터빈을 연결하는 주요계통이다. 운전조건으로 인한 배관시스템에 손상을 제한 할 수 있기 때문에 수격현상 해석은 중요하다. 배관시스템의 불안정한 유동에 의해 생성되는 수격현상은 압력의 과도한 변화, 진동 및 소음을 일으킬 수 있다. 주증기관 구조는 운전환경아래 압력맥동 및 여러 진동 등을 안전하게 견딜 수 있도록 설계되어야 한다. 본 논문에서는 정지 및 정상 운전기간 동안 배관에 유입되는 수격현상을 과도조건에 적용하여 ASME 피로수명 방법론과 유한요소해석에 따라 주증기관의 구조건전성을 평가하였다. 계산된 교번응력 및 피로응력 평가 결과, ASME 피로수명의 허용요건을 만족하였다.

• Journal of Mechanical Science and Technology
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• 제20권2호
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• pp.251-261
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• 2006

The objective of this work is to apply artificial neural networks for solving inverse problems in the structural optimization of a fiber optic pressure sensor. For the sensor under investigation to achieve a desired accuracy, the change in the distance between the tips of the two fibers due to the applied pressure should not interfere with the phase change due to the change in the density of the air between the two fibers. Therefore, accurate dynamic analysis and structural optimization of the sensor is essential to ensure the accuracy of the measurements provided by the sensor. To this end, a normal mode analysis and a transient response analysis of the sensor were performed by combining commercial finite element analysis package, MSC/NASTRAN, and MATLAB. Furthermore, a parametric study on the design of the sensor was performed to minimize the size of the sensor while fulfilling a number of constraints. In performing the parametric study, the need for a relationship between the design parameters and the response of the sensor was fulfilled by using a neural network. The whole process of the dynamic analysis using commercial finite element analysis package and the parameter optimization of the sensor were automated within the MATLAB environment.

• 한국철도학회논문집
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• 제20권3호
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• pp.320-328
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• 2017

철도차량에 폭 넓게 적용되고 있는 축상고무스프링의 노화에 따른 탈선안전도 영향을 분석하고자 노화 축상고무스프링 시료를 대상으로 특성시험을 수행하였다. 그리고 축상고무스프링 노화가 탈선 안전에 미치는 영향을 분석하기 위하여 주행 동특성 해석을 수행하였다. 사용연수 17년이 지난 롤고무 축상스프링 시료를 대상으로 한 상하방향 특성시험결과, 고무 노화로 인하여 변위 복원기능이 저하되었고 스프링강성이 현저히 증가하였다. 그리고 EN14363규격 적용 twist궤도 주행 시를 모사한 주행동특성 해석결과, 정상 차량모델(Case1)에 비하여 노화 축상스프링 특성을 적용한 차량모델(Case2)의 탈선계수와 윤중감소가 증가하여 탈선안전도는 저하하였다. 특히 급격한 선형 변동이 발생하는 천이구간 주행 시 윤중감소로 인한 탈선안전도는 취약하게 나타났다.

• Nuclear Engineering and Technology
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• 제22권1호
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• pp.66-74
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• 1990

원자력 7, 8호기에 장전된 17$\times$17 최적 핵연료집합체의 열수력학적 특성을 원자력 5, 6호기에 장전된 17$\times$17표준 핵연료집합체와 비교하여 분석하였다. 분석된 열수력학적 특성은 정상상태와 과도출력상태에서의 최소 DNBR, 연료봉 중심온도, 출구 기포율등이며, 아울러 연료봉의 중심이 용융되는 국부선출력과 원자로 운전변수들에 대한 DNBR 민감도 계수도 계산하였다. 사용된 코드는 COBRA-IV-I이며, 임계열속 계산에는 R형 그리드에 대해 수정된 W-3 상관식을, 기포율계산에는 drift-flux model을 이용하였다. 계산결과, DNB가 발생할 확률은 최적 핵연료집합체가 더 높았으나, 연료봉의 중심이 용융되는 국부선출력은 표준 핵연료집합체와 거의 동일한 것으로 나타났다.

• Korean Journal of Acupuncture
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• 제36권1호
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• pp.52-62
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• 2019

Objectives : The objective of this study was to investigate the effects of Zingiberis Rhizoma Pharmacopuncture(ZP) at GB30 and ST36 in neuropathic pain induced SD rats by the block of Transient Receptor Potential Vanilloid 1(TRPV1). Methods : Neuropathic pain in rats was induced by tibial and common peroneal nerve transection of right leg. The rat subjects were divided into 6 groups : normal(Nor, n=5), control(Con, n=5), neuropathic pain plus 2 mg/kg ZP injection at GB30 and ST36(ZP-A, n=5), 10 mg/kg ZP(ZP-B, n=5), 20 mg/kg ZP(ZP-C, n=5) and 0.45 mg/kg Tramadol(Tra, n=5). Three days after the surgery, injections were administered once a day for 17 days. Withdrawal response of neuropathic rats' legs were measured by stimulating the paw of Right leg with von frey filament, acetone and radient heat on day 3, 7, 11, 15, 19 after surgery. After all treatments were completed, c-Fos in the midbrain central gray and TRPV1 & TRPA1 of DRG(L5) were analyzed. Results : Groups ZP-B and ZP-C showed a meaningful decrease in the withdrawal response of mechanical allodynia, thermal hyperalgesia and cold allodynia compared to the control group(p<0.05, p<0.01, p<0.001). Groups ZP-B and ZP-C showed a meaningful decrease in the expression of c-fos and TRPV1 protein level compared to the control group(p<0.05, p<0.01, p<0.001). Conclusions : These results suggest that Zingiberis Rhizoma Pharmacopuncture at GB30 and ST36 could decrease mechanical & cold allodynia and thermal hyperalgesia by block the TRPV1 on the model of neuropathic pain.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2014년도 추계학술대회
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• pp.338-341
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• 2014

인지무선 (cognitive radio) 환경에서 2차사용자 (secondary user) 들의 일시적인 서비스 요구를 효과적으로 다룰 수 있는 스펙트럼풀링 (spectrum pooling) 기법이 최근 주목을 받고 있다. 스펙트럼풀링은 WSP (wireless service provider) 에 의해서 관리되며, 사용자의 요구가 있을 때, 금전적인 지불을 받고 스펙트럼을 2차사용자에게 대여해 주는 방식이다. 여기서, WSP는 가급적 많은 이윤을 남기기를 원한다. 이 논문에서 우리는 WSP가 유지하는 스펙트럼 풀 (pool) 을 확률 인벤토리모델 (probabilistic inventory model) 로 표현하고 2차사용자의 스펙트럼 요구가 정규분포를 따를 때, WSP가 비용을 최소화시키는 방향으로 인벤토리를 운영하는 전략을 제시한다. WSP가 지불해야하는 비용에는 일반적인 인벤토리 모델과 마찬가지로, 주문비용, 보관비용, 스톡아웃비용이다. 우리는 시뮬레이션을 통해, 고정된 인벤토리 레벨을 유지하는 것보다 확률 인벤토리모델에 의해 결정되는 레벨에 맞추어 유지하는 것이 총 소요비용을 절약할 수 있음을 보인다.