• 분석과학
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• 제8권3호
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• pp.229-236
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• 1995

생체시료에 존재하는 유리 아미노산의 분석을 위하여 pH 7.2의 완충용액 조건하에서 Amino Quant $C_{18}$ 컬럼에 diode array detector(DAD) 검출기가 부착된 HPLC에 의한 다단계 기울기 용리법이 사용되었다. 한국인 정신분열증 환자와 정상 한국인의 혈장시료내의 유리 아미노산은 3-mercaptopropionic acid 존재하에서 o-phthalaldehyde와 유도체 반응을 시켰다. 내부표준법에 의한 생체시료에서의 아미노산의 정량분석은 상대표준편차가 2~6%로서 재현성 있는 결과를 보여 주었다. 또한 한국인의 생체시료 중 아미노산의 함량은 외국인의 것과는 다른 결과를 얻었으며 정상인과 비정상인의 평균 tyrosine량은 큰 차이가 있었다.

• BMB Reports
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• 제40권1호
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• pp.72-81
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• 2007

In order to screen the aging related proteins in human normal colon epithelia, the comparative proteomics analysis was applied to get the two-dimensional electrophoresis (2-DE) profiles with high resolution and reproducibility from normal colon epithelial tissues of young and aged people. Differential proteins between the colon epithelia of two age groups were found with PDQuest software. The thirty five differential protein-spots were identified by peptide mass fingerprint (PMF) based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) and database searching. Among them there are sixteen proteins which are significantly up-regulated in the colonic mucosal epithelia of young people group, which include ATP synthase beta chain, electron transfer flavoprotein alpha-subunit, catalase, glutathione peroxidase 1, annexin A2 and heat shock cognate 71 kDa protein, etc.; There are nineteen proteins which are significantly up-regulated in the colonic mucosal epithelia of aged people group, which include far upstream element-binding protein 1, nucleoside diphosphate kinase B, protein disulfide-isomerase precursor and VDAC-2, etc.. The identified differential proteins appear to be involved in metabolism, energy generation, chaperone, antioxidation, signal transduction, protein folding and apoptosis. The data will help to understand the molecular mechanisms of human colon epithelial aging.

• 대한간호학회지
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• 제53권4호
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• pp.412-425
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• 2023

Purpose: Nurses play an important role in ensuring patient rehabilitation and are involved in all aspects of multidimensional rehabilitation. Therefore, strengthening rehabilitation nursing education is vital to ascertain high-quality rehabilitation and optimum outcomes. This study examined the effectiveness of a new teaching reform-a modified Six-Sigma-based training program-against a conventional educational program on rehabilitation specialist nurses' core competencies, post-training performance, and satisfaction. Methods: A quasi-randomized controlled trial was conducted to assess the effectiveness of the modified training program. We recruited 56 learners from the 2020 training course at the Hunan Rehabilitation Specialist Nurse Training Base as the control group. Sixty learners from the base's 2021 training course were recruited as the intervention group. Data were collected in a consistent manner from both groups after the training program was implemented. Results: Those who underwent the modified training program showed better improvement in all core competencies than those who underwent the conventional training program (p < .05); the scores for theoretical knowledge, clinical nursing lectures, reviews, and nursing case management improved significantly following the teaching reform (p < 0.05). Further, overall satisfaction as well as base management and theoretical teaching satisfaction improved significantly (p < .05). Conclusion: The modified training program strengthens rehabilitation nurses' base management abilities; enhances their core competencies; expands their interest in and breadth, depth, and practicability of theoretical courses; and updates the teaching methods.

• 대한인간공학회지
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• 제20권2호
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• pp.83-97
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• 2001

Korea has become an aged society according to the UN specifications. The number of the aged population will increase drastically, and the number of single aged people will also increase. Products used in our daily life are manufactured within the normal capabilities of people. Thus, aged people have encountering problems in using them. Numerous products are used in our daily lives. The purpose of this study is to find the acceptable torque for aged people to open the caps of processed food containers. Depending on the size and shape of the opening hand, hand operation has been classified into three categories. A total of one hundred and nine people participated in this study. Fifty nine people in the 20-30 year old range and fifty people in their 60-70's. Results of the study are as follows: 1) For all categories the acceptable cap torque data for the aged people are established. To satisfy 95% of the aged people, it was found that $74N{\cdot}cm$ for type A caps, and $141N{\cdot}cm$ for B type caps. and $214N{\cdot}cm$ for type C were the acceptable torque levels. 2) The appropriate level of torque for opening the cap was found to be 70% of the maximum torque for the aged people.(71.4% for type A. 71.4% for type B. 72.2% for type C). 3) Capabilities of the 70's drops sharply in function related to opening cap (maximum torque, gripping force, and wrist movement range). 4) Among aged subjects, 65.0% for type A, 42.0% for type B, and 68.8% for type C, had difficulties in opening the container caps.

• 한국운동역학회지
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• 제31권2호
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• pp.113-118
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• 2021

Objective: The purpose of this study was to investigate differences of landing strategy between people with or without chronic ankle instability (CAI) during double-leg drop landing. Method: 34 male adults participated in this study (CAI = 16, Normal = 18). Participants performed double-leg drop landing task on a 30 cm height and 20 cm horizontal distance away from the force plate. Lower Extremities Kinetic and Kinematic data were obtained using 8 motion capture cameras and 2 force plates and loading rate was calculated. Independent samples t-test were used to identify differences between groups. Results: Compared with normal group, CAI group exhibits significantly less hip internal rotation angle (CAI = 1.52±8.12, Normal = 10.63±8.44, p = 0.003), greater knee valgus angle (CAI = -6.78±5.03, Normal = -12.38 ±6.78, p = 0.011), greater ankle eversion moment (CAI = 0.0001±0.02, Normal = -0.03±0.05, p = 0.043), greater loading Rate (CAI = 32.65±15.52, Normal = 18.43±10.87, p = 0.003) on their affected limb during maximum vertical Ground Reaction Force moment. Conclusion: Our results demonstrated that CAI group exhibits compensatory movement to avoid ankle inversion during double-leg drop landing compared with normal group. Further study about how changed kinetic and kinematic affect shock absorption ability and injury risk in participants with CAI is needed.

• 대한인간공학회지
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• 제15권1호
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• pp.119-132
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• 1996

The objectives of this study are to investigate the measurements of clothing for the handicapped compared to that of the normal, and to present the basic data to make clothing for the handicapped who has specific needs. Questionnaires were administered to 927 Cerebral Palsies on height, weight, chest circumference, sitting height, and to 70 handicapped people using a supporting parasite on 18 measurement items. The results show that height, weight , and sitting height of the handicapped are smaller than those of the normal of equal age except for chest circumference. And, the values of the items for the lower half are smaller than the normal of equal age and those for the upper half, especially the items for the shoulder and arm, are greater. Compared to the values of the normal in the three standad size charts, the size charts using height and chest circumference are unsuitable to the handicapped, and the size chart using hip circumference is approximately suitable.

• 한국공간구조학회논문집
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• 제4권4호
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• pp.85-89
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• 2004

A frame element embedded normal to a shear wall or slab (shell element) is common in the structural systems. In that case there is a need for a membrane or shell element to have a normal rotation degree of freedom at each node in order to have a good result of stresses. Even if Many other people studied this area, All man, Cook and Sabir are representative investigators in this area. In this research paper, Sabir's methods of vertex rotation stiffness matrix in a membrane element are studied. New stiffness of vertex rotation are proposed by taking advantage of beam stiffness theory. Rectangular elements stiffness with rotational degree of freedom are compared in accuracy ratio each other.

• 지역사회간호학회지
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• 제15권4호
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• pp.587-599
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• 2004

Purpose: The purpose of this study is to compare abdomen-fat rate, life style and social-support between normal weight women and obese women. Method: 304 women objectives from their 30 to 59 years of age were selected living in Je-chon city, Chung-Buck province and their height and weight were measured from April 1st to June 30th, 2003. Data were classified into low-weight group ($18.5kg/m^2$), normal-weight group ($18.5{\sim}22.9kg/m^2$), over weight group ($23{\sim}24.9kg/m^2$), and obese group ($25kg/m^2$) following the Korean Conference of Obesity, 2001. in which 119 people in the normal weight group and 91 people in the obese group, i.e. total 210 people were analyzed in sequence. Using SPSS Win 10.1 Program, frequency and percentile, and by ANOVA, $X^2-test$ and t-test were treated. Results: The average age of obese women was 46.68 distributing 40.7% of forties and 39.6% of fifties while normal-weight women were average 41.73-year old distributing 53.8% of forties and 34.5% of thirties, which revealed aged in obese women. The body fat rate of obese women averaged $37.52{\pm}4.17%$, in which 98.9% of obese women and 21.0% of normal weight women with a more than 30% of body-fat rate resulted in a higher body-fat rate in obese women. The waists of obese women averaged $88.37{\pm}8.22cm$, in which more than 85cm showed in obese women of 68.2% and normal weight women of 7.6% indicating a higher waist-fat rate in obese women. The abdomen-fat rate of more than 0.85 of waist vs hip-fat showed 74.7% in obese women and 58.4% in normal weight women, indicating a higher abdomen-fat rate in obese women. Obese women and normal weight women showed significant differences in education level, number of children, religion, menstrual status, and mother's weight. Especially, obese women ate hotter or saltier food than normal weight women preferring meat. However, no significant differences appeared in marital status, social economic status. occupation. eating habits. smoking. drinking and physical exercise. Social support levels showed a lower rate in obese women than in normal weight women, indicating a statistically significant difference (p<.05). Observing areas of social support, obese women showed lower rates in attachment/intimacy, social integrity, opportunity of foster and confidence in value except help and instruction, which indicated a statistically significant difference (p<.05). Social support for obese women showed significant differences in age, education level, social hierarchy, religion and menstrual status. Obese women were more negative than normal weight women in health recognition, indicating a statistically significant difference (p<.01). Normal weight women showed higher health recognition when provided high social support and significantly low (p<.01) health recognition when provided low social support. However, there was no significant difference in health recognition in obese women whether high or low social support was given. The health recognition of obese women showed significant differences in age, education level, social hierarchy, number of children, menstrual status, physical exercise, eating habits, eating taste and preference of food. Conclusion: Obese women showed elder than normal-weight women, higher body-fat rate and abdomen-fat rate, lower social support, and a tendency to more negative health recognition. Therefore, providing weight-control programs for the treatment of obesity and prevention of recurrence for obese women to prevent progressing to adult disease and promote a healthy life, we suggest that better eating habits and the encouragement of regular physical exercise should be included, as well as total approachment on change of health recognition and social support would be needed.

• 대한지역사회영양학회지
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• 제6권1호
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• pp.43-50
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• 2001

This study was conducted to compare the dietary characteristics of middle-aged people with different obesity index or food habits. Questionnaires were collected from 480 subjects in Daejon. The data were analyzed by $X^2$-test and ANOVA. The subjects were distributed into the normal weight group(66.3%), overweight group(18.3%) and underweight(15.4%) based on BMI. Twenty-five percent of males and 23.0% of females in the 50＇s belonged to the overweight group. The least consumed food was milk or milk products among the five basic food groups. The frequency of exercise was low in their daily life. The had better food habits than the males. The overweight group had worse food habits than the normal weight or underweight group. The underweight group ate light meal and ate slowly. The better the subjects had, the more regularly they took breakfast(p＜0.001). The good food habits group were more interested in their dietary life and were more careful in selecting foods for their health than the bad food habits group(p＜0.001). Based on the results of this study, the practical education programs should be focused on more intake of milk or products and on daily exercise for the self-health maintenance of middle-aged people. Also, proper education programs should be developed for males and females in their 50＇s to practice weight control and regularity of meals in their life, and to utilize nutrition knowledge in dietary life. Further research on the comparision of dietary characteristics are needed with consideration of the subjects ratio according to BMI.

• 복식
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• 제53권1호
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• pp.1-15
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• 2003

This study as one of a series of systematic studies about dancing costumes will compare the costumes of the middle age with their normal style of dress. In brief, this study wants people to know about middle a9e dancing costumes and understand the culture in the middle ages. It was found that people's everyday clothes in the middle age such as Surcot. Surcot-ouvert, Pourpoint, Houppelande were used as dancing costumes. They were, however. changed from the public's clothes which were tight and long. Rather than wearing costume over others. dancers wore costumes which had slits on skirt or sleeves to increase motion. With the Wild Man of the Wood's which only nobles used for their dancing costumes. costumers highlighted the beauty of human body There were various costume materials used in the middle ages like silk. cotton fabrics, linen or brocade. These materials were used for Surcot and Pourpoint as dancing costumes. The naturalness of nature or geometric patterns also was expressed on the costumes. Further about those patterns, because the development of stained glass, vivid colors were used especially red, light green, blue etc. As for the hair styles used, dancers let their hair down and put a jeweled crown over their hair. In summation. dancers wore the same clothes that normal People did, but the costumes were different depending on social status and gender. The costumes of ordinary people's were based upon ordinary clothes that moved and emphasized the dynamic motion. On the other side, the court dancers' costumes were very fancy. symbolizing a measurement of nobles' from wealth and authority. as well as an expression of a sense of beauty, The main features of middle ages follows. : To emphasize vitality, there were long slits on the side of skirt. Hair decorations and jewels are more used than in the ancient age's. To hide a dancer's social status. they could use a mask. Wild Man of the Wood's was used for the body makeup. All these features of the dancing costumes must contribute to the progress of the dance in the middle age's.