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New index for the gifted students(G-Index) with EEG analysis (뇌파검사 자료를 기반으로 한 과학영재 판별 지수(G-Index) 개발과 적용)

  • Kim, Kyung-Hwa;Kim, Kyu-Han;Lee, Sun-Kil;Hur, Myung;Kim, Yong-Jin
    • Journal of Gifted/Talented Education
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    • v.15 no.1
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    • pp.67-84
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    • 2005
  • In this study we investigated the adequacy of tools for distinction gifted students through the comparison these mutual relation on the basis of data, like paper test, the depths interview score, and the rest data((TTCT: Torrance Tests of Creative Thinking, IQ test, FASP: Find A Shape Puzzle, V.T: Visualization Tests and Exp: experimental ability test), and analysis data of EEG test for examining the adequacy of tools for identification gifted students. So, we developed Brain Wave gifted Index(G-Index) for finding another distinction ability as using brain waves data. The standard of index development use gifted brain characteristic in closed-eyes rest state which is judged like that characteristic of distinction between gifted and normal students is the most clear and consistence. That is, the degree of unified pattern between each object and gifted PCA pattern was defined by Pearson method which added spatial mutual index to weight concept. This refer to mean number of spatial PCA pattern. Searching for the possibility of distinction gifted gave distinction effect in 76%. The result of regression analysis on the basis of mutual relation between the rest data is . The probability formula for distinct gifted group is as follow. $$P=\frac 1{1+e^{-[-0.018(TTCT)+0.057(IQ)+1.916(FASP)+0.682(V.T)+0.088(Exp.)+0.034(G-Index)-57.510]}}$$ The result of this calculation showed that probability for distinct in gifted group was very good(95.0%). On the basis of upper result, tools for identification gifted students should be estimated as using many-sided estimation data whatever possible. And following study about development, and operation of tools for distinction suitable to gifted student in science should be progressed.

Kinetics and Mechanism of the Anilinolysis of Dibutyl Chlorophosphate in Acetonitrile

  • Hoque, Md. Ehtesham Ul;Lee, Hai-Whang
    • Bulletin of the Korean Chemical Society
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    • v.33 no.2
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    • pp.663-669
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    • 2012
  • The nucleophilic substitution reactions of dibutyl chlorophosphate (3) with substituted anilines ($XC_6H_4NH_2$) and deuterated anilines ($XC_6H_4ND_2$) are investigated kinetically in acetonitrile at $55.0^{\circ}C$. The obtained deuterium kinetic isotope effects (DKIEs; kH/kD) are secondary inverse ($k_H/k_D$ = 0.86-0.97) with the strongly basic anilines while primary normal ($k_H/k_D$ = 1.04-1.10) with the weakly basic anilines. The DKIEs, steric effects of the two ligands, activation parameters, cross-interaction constants, variation trends of the kH/kD values with X, and mechanism are discussed for the anilinolyses of the nine ($R_1O$)($R_2O$)P(=O)Cl-type chlorophosphates. A concerted mechanism is proposed with a backside nucleophilic attack transition state for the strongly basic anilines and with a frontside attack involving a hydrogen-bonded four-center-type transition state for the weakly basic anilines on the basis of the magnitudes, secondary inverse and primary normal, and variation trends of the $k_H/k_D$ values with X.

Immature thymocyte antigen, JL1, as a possible immunodiagnostic and immunotherapeutic target for leukemia

  • Shin, Young Kee;Choi, Eun Young;Kim, Seok Hyung;Park, Seong Hoe
    • IMMUNE NETWORK
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    • v.1 no.1
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    • pp.1-6
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    • 2001
  • The identification of tumor-specific antigens has represented a critical milestone in cancer diagnosis and therapy. Clinical research in this area for leukemia has also been driven over the past few decades by the hope that surface antigens with restricted tissue expression would be identified. Disappointingly, only a small number of the leukemic antigens identified to date, meet sufficient criteria to be considered viable immunophenotypic markers. In this paper, we nominate anti-JL1 monoclonal antibody as an immunodiagnostic and immunotherapeutic candidate for leukemia. The JL1 molecule appears to be a novel cell surface antigen, which is strictly confined to a subpopulation of limited stages during the hematopoietic differentiation process. Despite the restricted distribution of the JL1 antigen in normal tissues and cells, anti-JL1 monoclonal antibody specifically recognizes various types of leukemia, irrespective of immunophenotypes. On the basis of these findings, we propose JL1 antigen as a tumor-specific marker, which shows promise as a candidate molecule for diagnosis and immunotherapy in leukemia, and one that spares normal bone marrow stem cells.

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Skin Pigment Recognition using Projective Hemoglobin- Melanin Coordinate Measurements

  • Yang, Liu;Lee, Suk-Hwan;Kwon, Seong-Geun;Song, Ha-Joo;Kwon, Ki-Ryong
    • Journal of Electrical Engineering and Technology
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    • v.11 no.6
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    • pp.1825-1838
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    • 2016
  • The detection of skin pigment is crucial in the diagnosis of skin diseases and in the evaluation of medical cosmetics and hairdressing. Accuracy in the detection is a basis for the prompt cure of skin diseases. This study presents a method to recognize and measure human skin pigment using Hemoglobin-Melanin (HM) coordinate. The proposed method extracts the skin area through a Gaussian skin-color model estimated from statistical analysis and decomposes the skin area into two pigments of hemoglobin and melanin using an Independent Component Analysis (ICA) algorithm. Then, we divide the two-dimensional (2D) HM coordinate into rectangular bins and compute the location histograms of hemoglobin and melanin for all the bins. We label the skin pigment of hemoglobin, melanin, and normal skin on all bins according to the Bayesian classifier. These bin-based HM projective histograms can quantify the skin pigment and compute the standard deviation on the total quantification of skin pigments surrounding normal skin. We tested our scheme using images taken under different illumination conditions. Several cosmetic coverings were used to test the performance of the proposed method. The experimental results show that the proposed method can detect skin pigments with more accuracy and evaluate cosmetic covering effects more effectively than conventional methods.

Plane-Strain Analysis of Auto-Body Panel Using the Rigid-Plastic Finite Element Method (강소성 유한요소법을 이용한 자동차 판넬 성형공정의 평면 변형해석)

  • 양동열;정완진;송인섭;전기찬;유동진;이정우
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.15 no.1
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    • pp.169-178
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    • 1991
  • A plane-strain finite element analysis of sheet metal forming is carried out by using the rigid-plastic FEM based on the membrane theory. The sheet material is assumed to possess normal anisotropy and to obey Hill's new yield criterion and its associated flow rule. A formulation of initial guess generation for the displacement field is derived by using the nonlinear elastic FEM. A method of contact treatment is proposed in which the skew boundary condition for arbitrarily shaped tools is successively used during iteration. In order to verify the validity of the developed method, plane-strain drawing with tools in analytic expression and with arbitrarily shaped tools is analyzed and compared with the published results. The comparison shows that the present method can be effectively used in the analysis of plane-strain sheet metal forming and thus provides the basis of approximate sectional analysis of panel-like sheet forming.

Effect of Initial Concentration on Pilot-Scale Composting of Diesel-Contaminated Soil (초기농도가 파일럿 규모의 디젤 오염토양 콤포스팅 처리에 미치는 영향)

  • 임재량;박준석;황의영;남궁완
    • Journal of Environmental Health Sciences
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    • v.28 no.5
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    • pp.35-41
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    • 2002
  • This study was conducted to evaluate the effect of initial concentration on pilot-scale composting of diesel-con-laminated soil. Sandy soi] was used in this study. Target contaminant, diesel oil, was spiked. at about 10,000, 25,000, and 50,000 mg TPH/kg of dry roil. Mit ratio of soil to sludge was 1:0.5 as wet weight basis. Removal efficiencies for initial concentrations of 12,966,23,894 and 51,042 mg TPH/kg were 90, 93 and 54%, respectively, during 33 days of composting. Normal alkanes in TPH ranged from 15 to 22% in initial soils. Volatilization of individual normal alkane in 1,999 mg n-alkanes/kgwas completed within 4 days, while n-alkane compounds of Cl1-Cl4 in 5,270 and 9,836 mg n-alkanes/kg were volatilized continuously during 33 days of composing operation. The first order degradation rate con-stants for 12,966, 23,894, and 51,042 mg TPH/kg were 0.058, 0.076, and 0.022/day, and those for 1,997 5,270, and 9,836 mg n-alkanes/kg were 0.093, 0.100, and 0.019/day, respectively. Considering TPH removal rate, $CO_2$porduction rate, and dehydrogenase activity, the concentration of 51,042 mg TPH/kg inhibited biodegradation of diesel-composting.

Kinetics and Mechanism of the Anilinolysis of Dicyclohexyl Phosphinic Chloride in Acetonitrile

  • Hoque, Md. Ehtesham Ul;Lee, Hai-Whang
    • Bulletin of the Korean Chemical Society
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    • v.32 no.6
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    • pp.1997-2002
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    • 2011
  • The nucleophilic substitution reactions of dicyclohexyl phosphinic chloride [3; $cHex_2$P(=O)Cl] with substituted anilines ($XC_6H_4NH_2$) and deuterated anilines ($XC_6H_4ND_2$) are investigated kinetically in acetonitrile at 60.0 $^{\circ}C$. The anilinolysis rate is too slow to be rationalized by the stereoelectronic effects. The rate is contrary to expectations for the electronic influence of the two ligands and exhibits exceptionally great negative deviation from the Taft's eq. The deuterium kinetic isotope effects (DKIEs) involving deuterated anilines invariably change from primary normal ($k_H/k_D$ > 1; max $k_H/k_D$ = 1.10 with X = 4-MeO) with the strongly basic anilines (X = 4-MeO, 4-Me, 3-Me) to secondary inverse ($k_H/k_D$ < 1; min $k_H/k_D$ = 0.673 with X = 3-Cl) with the weakly basic anilines (X = H, 4-F, 4-Cl, 3-Cl). A concerted $S_N2$ mechanism is proposed on the basis of both secondary inverse and primary normal DKIEs. The obtained DKIEs imply that the fraction of a frontside attack increases as the aniline becomes more basic. A hydrogen-bonded, four-center-type transition state is suggested for a frontside attack, while the trigonal bipyramidal pentacoordinate transition state is suggested for a backside attack.

Effects of Salviae Miltiorrhizae Radix on the Diet-induced Hyperlipidemia in Rats (단삼이 흰쥐의 식이성 고지혈증에 미치는 영향)

  • Kim, Min su;Seo Il bok;Kim Jeung beum
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.2
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    • pp.431-435
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    • 2004
  • The purpose of this study was to examine the effects of Salviae Miltiorrhizae Radix on the high fat diet-induced hyperlipidemia in rats. Sixty male Sprague-Dawley rats, around 270g of B.W., were divided into normal, control, sample A and sample B group. Normal and control groups were orally administrated with saline during 4 weeks, sample A and sample B with 252.5mg/kg(rat) and 420.1 mg/kg(rat) of solid extract of Salviae Miltiorrhizae Radix during 4 weeks respectively. Blood samples were collected from each of animals at 4 weeks, and used for the blood chemical analysis. Animals were sacrificed at 4 weeks, and chemical analysis was performed on the collected liver samples. The serum total cholesterol, HDL-cholesterol, LDL-cholesterol levels of sample A group were significantly decreased compared with the control group. On the basis of these of results, it is confirmed that Salviae Miltiorrhizae Radix has the curative effects on the hyperlipidemia in rats induced by high fat diet

A Case Study on imposing anti-dumping duty against Chinese Ceramic Tile (중국산 도자기질 타일 반덤핑관세부과 사례에 관한 연구)

  • Kim, Hee-Kil
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.42
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    • pp.337-364
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    • 2009
  • Trade remedy is the system that additional duty or import quantity restriction would be imposed on the import products, in case that unfair imports damage domestic industry or even proper import products damage significantly domestic industry. The system is secured by the act of unfair trade practice investigation & industrial damage remedy, tariff act, WTO agreement. Anti-dumping duty act is the system that duties are assessed with the equal or less amount of the difference between normal transaction price and dumping price, in case that the product imported under dumping price causes or may cause damages in domestic industry, or the development of domestic industry should be delayed practically. Recently, the problems related with anti-dumping duty imposed as the part of the trade remedy occur frequently. It is necessary to discuss whether the anti-dumping duty act is practically trade remedy which does comply with GATT regulations and WTO agreements as the criteria of international law and is in line with the intent of domestic act in the suffered country, or it does return to protective trade or reduce the protection of consumer. On the basis of this discussion, it would be difficult to impose the antidumping duty on industrial products in order to protect domestic industry, when considering the expected free trade agreements of Korea-US, Korea-China and Korea-Japan. In order to survive under the current severe competition of world trade market, companies should raise the competitiveness by themselves without relying on the current trade acts to provide with a certain protection. This thesis should bring those attentions.

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Evaluation of Neuronal Dysfunction in Schizophrenia before and after Neuroleptic Treatment by ??H MRS

  • C, Bo-Young;Paik, In-Ho;Lee, Chang-Uk;Lee, Hyoung-Koo;Suh, Tae-Suk
    • Journal of the Korean Magnetic Resonance Society
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    • v.5 no.1
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    • pp.56-65
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    • 2001
  • Localized in vivo proton magnetic resonance spectroscopy (MRS) was performed to evaluate metabolic alterations in the right and left frontal lobe before and after neuroleptic treatment of schizophrenic patients (n=24) and a group of healthy normal subjects (n=20). Proton metabolic ratios obtained from the 8㎤ yokels in the right and left frontal lobe were compared with the clinical assessment of PANSS for each subject. There was no significant difference in the metabolic ratios between the right and the left frontal lobes in either the schizophrenic group or the control group, indicating no laterality. Compared with those of the normal control group, NAA/Cr and (GABA+Glu)/Cr ratios of the schizophrenic patients showed significantly lower (p=0.023) and higher (p=0.005) value, respectively. The (GABA+Glu)/Cr ratio of the schizophrenic patients was generally decreased after neuroleptic treatment, while the NAA/Cr ratio was not changed. Significant correlation between the (GABA+Glu)/Cr ratio and the clinical symptom scores assessed by PANSS was established. The present study supports the “hypofrontality” hypothesis of schizophrenia on the basis of the altered metabolic ratios before and after neuroleptic treatment.

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