• Preventive Nutrition and Food Science
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• 제8권2호
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• pp.191-195
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• 2003

We investigated the effects of gamma irradiation on the microbiological, chemical and sensory qualities of bulgogi, a traditional Korean meat product. Gamma irradiation reduced the number of coliform bacteria and bacterial colonies counted in Salmonella-Shigella selective agar to a non-detectable level. Thermophillic microorganisms (mainly Bacillus spp.) in bolgogi refrigerated for 20 days were also significantly reduced by 3 log cycles by 2.5 to 7.5 kGy of irradiation, compared to the control. Electron donating ability and shear force of ready-to-cook bulgogi was not significantly affected by gamma irradiation. Irradiation increased the 2-thiobarbituric acid reactive substances (TBARS) value. The irradiated, raw, ready-to-cook bulgogi had significantly higher scores in color and appearance than those of non-irradiated controls from sensory evaluation. The overall acceptance of cooked bulgogi had higher scores in non-irradiated or 2.5 kGy-irradiated bulgogi than the 5.0- or 7.5-kGy irradiated counterparts. In conclusion, irradiation at 2.5 kGy is recommended as a method to improve shelf-life, safety, and to achieve acceptable quality of ready-to-cook bulgogi without any adverse changes in the sensory characteristics.

• Structural Engineering and Mechanics
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• 제71권5호
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• pp.545-552
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• 2019

The analysis and design of complex structures like sandwich-panel elements are difficult; the use of finite element method for the analysis is complicated and time consuming when non-linear effects are considered. On the other hand, artificial neural network (ANN) models can capture the non-linear effects and its application requires lesser computational demand. Two ANN models were trained, tested and validated to compute the force for a given displacement of a sandwich-type roof element; 2555 force and element deformation pairs were used for training the ANN models. For the models trained without considering the damping effect, there were two values in the input layer: maximum displacement and current displacement, and for the model considering damping, displacement from the previous step was used as an additional input. Totally, 400 ANN models were trained. Results show that there is a good agreement between the experimental and simulated data, and the models showed a good performance with a mean square error value of 4548.85. Both the ANN models could simulate the inelastic behaviour, loss of rigidity, and evolution of permanent displacements. The models could also interpolate and extrapolate, which enables them to be used as an analysis and design tool for such complex elements.

• 한국과학교육학회지
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• 제35권1호
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• pp.143-157
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• 2015

본 연구의 목적은 한국 전통 과학 지식의 과학 교육 가능성에 대해 파악하고자 함에 있다. 한국 전통 과학을 소재로 과학적 개념, 역사적 지식, 문화적 경험 등이 포함된 실험과 그룹 활동, 탐방을 포함한 5개 프로그램을 개발했다. 개발한 프로그램의 주제는 역법, 앙부일구의 원리, 과학자 장영실, 한국의 고대 자연 기록, 경복궁 탐방 등이었다. 이 프로그램에 참여한 고등학생들의 프로그램 전후 인식 조사, 수업 관찰 자료, 수업 활동 자료, 면담을 분석한 결과, 학생들의 한국 전통 과학에 대한 인식은 문화적 범주 내에서 과학적 요소를 찾는 수준을 넘어서서 자연 과학으로서의 한국 전통 과학 가치로 변해갔다. 또한, 우리 전통 과학에 대한 기대감을 과학적, 실용적, 정서적 측면에서 표현했는데, 한국 전통과학의 실용적, 정서적 측면들이 학생들에게는 비과학적 측면으로 인식되기도 하였다. 또한 이들은 서양 과학과 한국의 TSK와의 관계를 통해 과학에 대한 세계관을 드러냈는데 크게 다섯가지로 분류되었다. 학생들은 전반적으로 한국 전통 과학을 아끼고 사랑하는 마음을 가지고 있었지만, 한국 전통 과학의 과학적 가치에 대해서는 혼란스러움을 나타냈다. 학생들은 우리가 배우고 있는 과학이 어떠한 의미를 가지고 있는지 고찰하고 과학 교육자들은 그것을 세심하게 검토할 필요성이 제기되었다. 아울러 우리가 한국의 TSK에 대한 지식을 학생들에게 전달하는 방법에 대해 다시 생각해 보고, 한국 TSK에 대한 학문적, 과학교육적인 심층 연구가 이어져야 할 것이다.

• 대한예방한의학회지
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• 제20권1호
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• pp.145-159
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• 2016

Objectives : The aim was to investigate the characteristics of low dose effect and non monotonic dose responses(NMDRs) and to predict the influence it might have on the health and medicine, traditional Korean medicine. Methods : By investigating recently published major literatures related to low dose effect and NMDRs, the definition, mechanism, major related fields, and the influence on public health and medicine has been categorized and summarized. Results : Although there are still heated debates about the definition of low dose, it implies the biological responses in environmental exposure level and the NDMDRs means the nonlinear relationship between the dose-response in the slope sign change. Also, it implies the new form of the curve showing a U, reverse U shape, and the slop sign constantly changing showing various forms. This mechanism is because the two acceptor shows opposing effects to toxic materials and the affinity is different along with the numerical value that increase and decrease being different. These characteristics generally appear in endocrine disrupters such as bisphenol A, agricultural pesticides, metal, and radiation. The research field in the public health and medical treatment is obesity, problems in metabolism, growth hormone treatment, climacteric treatment, breast cancer, intake of Korean traditional medicine for pregnancy, menopause and phytoestrogen. Conclusions : As a result of discussing implications, NMDRs is a particular effect in low dose and heated debates surround this response, research is being conducted surrounding the field of obesity, problems in metabolism, growth hormone treatment, climacteric treatment, breast cancer, intake of Korean traditional medicine for pregnancy, menopause, and phytoestrogen. More research and interest in needed as it can have a massive influence in the public health and medicine.

• 정보과학회 논문지
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• 제43권2호
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• pp.152-162
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• 2016

비 휘발성 메모리를 할당받아 사용하기 위해서는 비 휘발성 메모리 전용의 가비지 수집 기법이 필수적이다. 본 논문에서는 이를 위해 비 휘발성 메모리 할당 정보 관리용 메타데이터를 설계하였고 이를 Allocation Tree라고 명명하였다. 이 메타데이터는 검색 속도의 향상을 위해 트리 자료구조를 이용하여 구성되었고, 하나의 노드 안에는 할당 메모리 시작 주소와 저장소 ID 정보가 키-밸류 형태로 저장된다. 비 휘발성 메모리 공간이 부족하여 가용 공간이 70% 이하로 떨어지면 가비지 수집기가 작동되어 가비지 수집을 수행하게 되고 Allocation Tree와 사용자 데이터를 비교하여 가비지를 판정한다. 본 연구에서는 이 알고리즘을 Persistent Heap기반의 메모리 할당 플랫폼인 'HEAPO'에서 구현하여 정상적으로 동작함을 증명하였다.

• 한국식품조리과학회지
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• 제21권4호
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• pp.422-432
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• 2005

Shinuncho(Angelica keiskei koidz)sulgi is a kind of steamed rice cake by an earthenware steamer. I made Shinuncho-sulgi samples with different amounts of Angelica keiskei koidz - powder and different types of sugars (sugar or honey). The more Angelica keiskei koidz powder it has the bitter it tastes but the lower sweetness, moistness and chewiness it has. Samples with honey have higher sweetness, moistness and chewiness but lower bitterness and after-swallowing than ones with sugar. Color is Shinsuncho-sulgi with $3\%$ of Angelica keiskei koidz - powder and honey has been judged to have the best quality. Flavor and Overall-acceptability are Shinsuncho-sulgi with $2\%$ of Amge;oca keiskei koidz - powder and honey has been judged to have the best quality. The more Angelica keiskei koidz powder it has the higher hardness but the significantly cohesiveness, springiness, gumminess, and chewiness it has. Samples with honey have higher hardness, springiness, cohesiveness, gumminess and chewiness, but lower adhesiveness, than ones with sugar. The moisture content of Shinsuncho-sulgi is $35.89\~37.08\%$. Samples with honey have higher b-value but lower L-value and a-value than ones with sugar. Based on the results of the study, the best ratio of ingredients is as follow non-glutinous flour 196g, Angelica keiskei koidz powder $2\%$ (4g), honey 35ml, salt 2g, water 20ml and $37.08\%$ of moisture content.

• 한국정보처리학회논문지
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• 제4권12호
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• pp.3185-3199
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• 1997

본 논문에서는 블록 근사화식을 적응적으로 선택하여 프랙탈 계수를 결정함으로서 기존의 프랙탈 부호화 방법에서 문제가 되는 부호화 시간을 개선하는 방법과 복원 영상의 화질을 향상시킬 수 있는 방법을 제안한다. 첫 번째로 부호화 시간을 단축하기 위해 밝기값과 분산에 의해 특성이 결정된 Domain 블록을 선형 리스트로 구성한 후 l차 허용오차 임계치에 의해 블록 탐색 시간을 제어할 수 있게 하였다. 두 번째로 블록 분할 레벨을 3단계로 하여 부호화할 때 최저 분할 레벨의 Range 블록이 만족할 만한 근사화 오차를 갖는 Domain블록을 찾지 못하면 그 블록에 한하여 밝기항을 비선형 변환식으로 새로운 변환 계수를 결정하여 화질을 향상시켰다. 제안한 방법으로 실험한 결과 기존의 부호화 방식보다 부호화 시간은 2배이상 향상되었고 동일한 압축율에서 PSNR값은 1-2dB정도가 향상되었다.

• 한국방사선학회논문지
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• 제8권1호
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• pp.19-26
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• 2014

본 논문에서는 프랙탈 부호화시 변환식의 계수를 찾는 과정에서 블럭의 탐색영역을 줄이기 위해 탐색영역인 도메인 블럭의 특성을 화소의 밝기의 평균에 의한 클래스와 분산에 의한 클래스로 분류하여 리스트를 구성한 후 레인지 블럭과 같은 클래스를 가지는 도메인 블럭만 검색하도록 하면서 도메인 블록 탐색시 1차 허용 오차 한계값을 제어하여 리스트 탐색시 RMS값에 일정 허용오차 이내의 값을 가지면 리스트를 끝까지 탐색하지 않고 변환값을 결정하도록 하여 부호화 시간을 향상시켰다. 또한 퀴드트리 분할법으로 레인지 블럭의 크기를 가변시켜 변환($w_i$)의 수를 줄임으로서 압축효율을 높이고 도메인 레인지 블럭의 크기에 따라 탐색 영역의 탐색 밀도와 허용오차를 변화시켰을 때 화질 개선 여부를 검토하였다. 제안된 방법으로 부호화한 결과 부호화 시간은 허용오차의 범위에 따라 향상되며 압축효과는 높아 졌고 PSNR값은 다소 떨어졌으나 거의 무시할 수 있을 정도의 변화가 있었다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3451-3455
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• 2014

Background: The serum carcinoembryonic antigen (CEA) level can reflect tumor growth, recurrence and metastasis. It has been reported that epidermal growth factor receptor (EGFR) mutations in exons 19 and 21may have an important relationship with tumor cell sensitivity to EGFR-TKI therapy. In this study, we investigated the clinical value of EGFR mutations and serum CEA in patients with non-small cell lung cancer (NSCLC). Materials and Methods: The presence of mutations in EGFR exons 19 and 21 in the tissue samples of 315 patients with NSCLC was detected with real-time fluorescent PCR technology, while the serum CEA level in cases who had not yet undergone surgery, radiotherapy, chemotherapy and targeted therapy were assessed by electrochemical luminescence. Results: The mutation rates in EGFR exons 19 and 21 were 23.2% and 14.9%, respectively, with the two combined in 3.81%. Measured prior to the start of surgery, radiotherapy, chemotherapy and targeted treatment, serum CEA levels were abnormally high in 54.3% of the patients. In those with a serum CEA level <5 ng/mL, the EGFR mutation rate was 18.8%, while with 5~19 ng/mL and ${\geq}20ng/mL$, the rates were 36.4% and 62.5%. In addition, in the cohort of patients with the CEA level being 20~49 ng/mL, the EGFR mutation rate was 85.7%, while in those with the CEA level ${\geq}50ng/mL$, the EGFR mutation rate was only 20.0%, approximately the same as in cases with the CEA level<5 ng/mL. Conclusions: There is a positive correlation between serum CEA expression level and EGFR mutation status in NSCLC patients, namely the EGFR mutation-positive rate increases as the serum CEA expression level rises within a certain range (${\geq}20ng/mL$, especially 20~49 ng/mL). If patient samples are not suitable for EGFR mutation testing, or cannot be obtained at all, testing serum CEA levels might be a simple and easy screening method. Hence, for the NSCLC patients with high serum CEA level (${\geq}20ng/mL$, especially 20~49 ng/mL), it is worthy of attempting EGFR-TKI treatment, which may achieve better clinical efficacy and quality of life.

• Journal of Information Processing Systems
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• 제17권2호
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• pp.306-317
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• 2021

The unbalance between system ergodic sum rate and high fairness is one of the key issues affecting the performance of non-orthogonal multiple access (NOMA) system. To solve the problem, this paper proposes a power allocation algorithm to realize the ergodic sum rate maximization of NOMA system. The scheme is mainly achieved by the construction algorithm of fair model based on α fair utility function and the optimal solution algorithm based on the interior point method of penalty function. Aiming at the construction of fair model, the fair target is added to the traditional power allocation model to set the reasonable target function. Simultaneously, the problem of ergodic sum rate and fairness in power allocation is weighed by adjusting the value of α. Aiming at the optimal solution algorithm, the interior point method of penalty function is used to transform the fair objective function with unequal constraints into the unconstrained problem in the feasible domain. Then the optimal solution of the original constrained optimization problem is gradually approximated within the feasible domain. The simulation results show that, compared with NOMA and time division multiple address (TDMA) schemes, the proposed method has larger ergodic sum rate and lower Fairness Index (FI) values.