• Title/Summary/Keyword: non-segregation

Search Result 102, Processing Time 0.03 seconds

Sub-Ciliary Segregation of Two Drosophila Transient Receptor Potential Channels Begins at the Initial Stage of Their Pre-Ciliary Trafficking

  • Kwon, Youngtae;Lee, Jeongmi;Chung, Yun Doo
    • Molecules and Cells
    • /
    • v.43 no.12
    • /
    • pp.1002-1010
    • /
    • 2020
  • Cilia are important eukaryotic cellular compartments required for diverse biological functions. Recent studies have revealed that protein targeting into the proper ciliary subcompartments is essential for ciliary function. In Drosophila chordotonal cilium, where mechano-electric transduction occurs, two transient receptor potential (TRP) superfamily ion channels, TRPV and TRPN, are restricted to the proximal and distal subcompartments, respectively. To understand the mechanisms underlying the sub-ciliary segregation of the two TRPs, we analyzed their localization under various conditions. In developing chordotonal cilia, TRPN was directly targeted to the ciliary tip from the beginning of its appearance and was retained in the distal subcompartment throughout development, whereas the ciliary localization of TRPV was considerably delayed. Lack of intraflagella transport-related proteins affected TRPV from the initial stage of its pre-ciliary trafficking, whereas it affected TRPN from the ciliary entry stage. The ectopic expression of the two TRP channels in both ciliated and non-ciliated cells revealed their intrinsic properties related to their localization. Taken together, our results suggest that sub-ciliary segregation of the two TRP channels relies on their distinct intrinsic properties, and begins at the initial stage of their pre-ciliary trafficking.

Multiculturalism and Socio-Spatial Segregation of Honolulu in the 1920s (1920년대 호놀룰루의 다문화주의와 집단간 사회-공간적 분리)

  • Lee, Young-Min
    • Journal of the Korean Geographical Society
    • /
    • v.42 no.5
    • /
    • pp.675-690
    • /
    • 2007
  • It has been widely believed that the ethnic relations in Honolulu and Hawai'i in the early twentieth century were little associated with racist ideology because the white race was minority in terms of the racial composition. In reality, however, the racial and ethnic issues have played a major role in forming the past and present relations among ethnic groups. This study shows that the white-supremacy ideology exerted a strong influence on minority groups in Honolulu throughout the immigration and settling-down process, as much as in the mainland U.S. Clear occupational stratification and residential segregation among the ethnic groups in Honolulu represented almost the same situation as in mainland cities. The social segregation and spatial propinquity of their residential neighborhoods facilitated the construction of dichotomized identity: "Local" versus "Haole". Such transformed identities were a product of on-going inter-ethnic negotiation process embedded in the non-white multi-ethnic neighborhoods.

Determination of Soil Sample Size Based on Gy's Particulate Sampling Theory (Gy의 입자성 물질 시료채취이론에 근거한 토양 시료 채취량 결정)

  • Bae, Bum-Han
    • Journal of Soil and Groundwater Environment
    • /
    • v.16 no.6
    • /
    • pp.1-9
    • /
    • 2011
  • A bibliographical review of Gy sampling theory for particulate materials was conducted to provide readers with useful means to reduce errors in soil contamination investigation. According to the Gy theory, the errors caused by the heterogeneous nature of soil include; the fundamental error (FE) caused by physical and chemical constitutional heterogeneity, the grouping and segregation error (GE) aroused from gravitational force, long-range heterogeneous fluctuation error ($CE_2$), the periodic heterogeneity fluctuation error ($CE_3$), and the materialization error (ME) generated during physical process of sample treatment. However, the accurate estimation of $CE_2$ and $CE_3$ cannot be estimated easily and only increasing sampling locations can reduce the magnitude of the errors. In addition, incremental sampling is the only method to reduce GE while grab sampling should be avoided as it introduces uncertainty and errors to the sampling process. Correct preparation and operation of sampling tools are important factors in reducing the incremental delimitation error (DE) and extraction error (EE) which are resulted from physical processes in the sampling. Therefore, Gy sampling theory can be used efficiently in planning a strategy for soil investigations of non-volatile and non-reactive samples.

Numerical analysis of the continuous casting process in the presence of thermo-solutal convection (열농도대류를 고려한 연속주조공정의 수치해석)

  • Jeong, Jae-Dong;Yu, Ho-Seon;Lee, Jun-Sik
    • Transactions of the Korean Society of Mechanical Engineers B
    • /
    • v.21 no.3
    • /
    • pp.445-456
    • /
    • 1997
  • Continuous casting process is numerically analyzed using the continuum model in a non-orthogonal coordinate system. Flow damping in the mush is modeled by combining the viscosity dependence on liquid fraction in dilute mush and the permeability dependence on liquid fraction in concentrated mush. The effect of turbulence is indirectly considered by effective diffusivity determined elsewhere by experiment. The main objective is to investigate the effects of casting parameters such as casting speed and tundish superheat on the distribution of surface temperature, shell thickness, metallurgical length and centerline segregation. Some of the computed results are compared with available experiments, and reasonable agreements are obtained.

An Experimental Study on Underwater Concrete Using the Antiwashout Admixture (수중불분리성혼화제를 첨가한 콘크리트의 특성에 관한 실험적 연구)

  • 정범석;최계식;이규재
    • Proceedings of the Korea Concrete Institute Conference
    • /
    • 1993.04a
    • /
    • pp.47-52
    • /
    • 1993
  • Admixtures for concrete placed underwater have been developed to the stage that they are now widely used. The use of this type of product allows concrete to be placed underwater with far less risk than was previously possible. One of the problems facing users of underwater concreting admixtures is how does one test such products in order to access their performance initially while minimizing the expense of carrying out site trials. This paper will introduce three categories of laboratory test for underwater concrete listed next : fluidity test, non-segregation test, strength test. Trial underwater concretes were ordinary Portland cement. Strength and workability development and segregation resistance properties of the concrete under the coexistence of some kinds of superplasticizer were studied for this laboratory tests.

  • PDF

Comparative Analyses for Aroma and Agronomic Traits of Native Rice Cultivars from Central Asia

  • Sarhadi, Wakil Ahmad;Hien, Nguyen Loc;Zanjani, Mehran;Yosofzai, Wahida;Yoshihashi, Tadashi;Hirata, Yutaka
    • Journal of Crop Science and Biotechnology
    • /
    • v.11 no.1
    • /
    • pp.17-22
    • /
    • 2008
  • Aromatic rice has become popular owing to its aroma. Growing demand for aromatic rice has spurred interest in the development of domestic cultivars that offer similar combinations of grain attributes such as texture, cooking characteristics, aroma, and taste. In this study, the most important agronomic attributes and aroma of 26 cultivars from Afghanistan, Iran, and Uzbekistan, and controls from Japan, Thailand, and India were characterized. Also $F_2$ populations derived from the cross between(Jasmine 85 aromatic$\times$Nipponbare non-aromatic) and(Jasmine 85$\times$Basmati 370 aromatic) were obtained. Tasting individual grains, cooking test, 1.7% KOH sensory test, and molecular marker analysis have been applied to distinguish between aromatic and non-aromatic rice. Diversity for some traits of agronomic importance, such as plant height was detected among countries, e.g. Afghan cultivars classified as tall, and Iranian and Uzbek intermediate and short, respectively. Differentiations of panicle, grain, leaf, basal internode, and culm dimension among rice cultivars, indicating the source of rice diversity in Central Asia. According to the results, 6 of 10, 2 of 7, and 0 of 6 of Afghan, Iranian, and Uzbek rice cultivars were scored as aromatic, respectively. Therefore, Afghan cultivars are a good source of aromatic rice germplasm for Central Asia. The expression between aromatic and non-aromatic, and aromatic and aromatic combinations has been evaluated. The observed segregation ratio of these crosses in the $F_2$ populations was tested by $x^2$ analysis against the expected ratio for a single gene. A segregation ratio of 3:1 between non-aromatic and aromatic combination has been detected, while segregation has not been detected between the aromatic and aromatic combinations. Also, parallel results were obtained from the tested aromatic rice cultivars. Thus, our results suggest that a single recessive gene controls aroma in all aromatic rice cultivars.

  • PDF

Segregation of the Lowest Social Class and Transformation of Communal Consciousness : As a Case Study of Douwa District in Yao City, Osaka (사회적 최하층계급의 거주지분리와 공동체의식의 변화 : 대판부(大阪府) 팔미시(八尾市)의 동화지구를 사례로)

  • Jo, Hyun-Mi
    • Journal of the Korean association of regional geographers
    • /
    • v.15 no.6
    • /
    • pp.803-819
    • /
    • 2009
  • This study explores of the lowest social class segregation in the residential area of Yao city of the Osaka Prefecture. The Buraku people, who constitute a social class that was the object of societal discrimination and exclusion since the beginning of modem times, formed a segregated residential area of their own. During the process of an organized struggle against discrimination that was institutionally recognized, communal consciousness among the constituents was consolidated. Moreover, in the Yao city, Korean immigrants in Japan, another discriminated group, as well as Vietnamese refugees and Chinese, who are also social minorities, increased in number. Also, activities by the Buraku people and Korean immigrants in Japan to defend human rights and the rights of social minorities began to unfold. Recently, the number of small scale factories in the Buraku's Douwa District decreased due to relocation of manufacturing companies elsewhere throughout Japan and to the effects of depression. New non-Buraku houses began to appear one by one on the site where factories started to disappear. While the spatial separatism of Yao city, as part of the isolated Douwa District, is weakening, the struggle based on communal consciousness among the social minorities and continued human rights activity is exerting great influence upon the administrative policy of Yao city. In the case of Yao city, while the visual appearance of spatial segregation is weakening, the communal consciousness among the regional residents remains. From this perspective, it can be said that this case represents a modified form of isolated space or the social pattern of segregation which is in the stage of extinction.

  • PDF

An Experimental Study on the Properties of High Flowing Concrete according to Water/Binder Ratio(W/B) (물결합재비에 따른 고유동콘크리트의 특성에 관한 실험적 연구)

  • 김무한;최세진
    • Journal of the Korea Concrete Institute
    • /
    • v.13 no.4
    • /
    • pp.329-335
    • /
    • 2001
  • Recently, in many laboratories and institutes it is being studied on the high flowing concrete widely, which has high fluidity, non-segregation ability and fillingability, and sometimes being applied to the construction field actually. And the fluidity properties of high flowing concrete are influenced according to the several factors ; binder content, water/binder ratio and water content etc. This is an experimental study to compare and analyze the effect of water/binder ratio and water content on the properties of high flowing concrete. For this purpose, the mix proportion of high flowing concrete according to water/binder ratio(W/B : 0.30, 0.35, 0.40, 0.45) and water content (W : 155, 165, 175, 185 kg/㎥) was selected. And then slump-flow, V-lot, L-passing test in fresh concrete, and compressive strength, freezing and thawing test in hardened concrete were peformed. According to test results, it was found that the viscosity of all those high flowing concrete with the water content 175 kg/㎥ was satisfied with 50 cm pass time of slump flow prescribed by Japanese Architectural Standard Specification (JASS 5) - from 3 to 8 seconds. And non-segregation ability of concrete with W/B 0.35 was better than the other mix proportions. Especially, the compressive strength after curing 24 hours(1 day) of all high flowing concrete was higher than that prescribed by JASS 5(50 kgf/㎠).

An Experimental Study on the Development of Non-Compacting Concrete Using Viscosity Agent and Fly-ash (증점제 및 플라이애쉬를 이요한 다짐불요 콘크리트의 개발에 관한 실험적 연구)

  • 김기철;한민철;원종필;최은규;한천구
    • Proceedings of the Korea Concrete Institute Conference
    • /
    • 1996.10a
    • /
    • pp.266-270
    • /
    • 1996
  • The objective of this study is to develop the Non-compacting concrete with mormal strength in practice by using viscosity agent and flyash. In this paper, we present the reference data about not only the properties of Non-compacting concrete at fresh state such as flowability, segregation-resistibility, placebility and so on but, optimum mixing design using viscosity agent and flyash. The test results indicate that optimum dosage of viscosity agent in combination of flyash in 50% of W/C is about 400g/$\textrm{m}^3$ with 20% of the ratio of flyash replacement.

  • PDF

Design Program of Deck Plate Slab System with Non-welding Truss Type Reinforced Bar (철근트러스 압접 데크플레이트 바닥 구조의 설계 프로그램)

  • Yoon, Myung-Ho;Oh, Sang-Hoon
    • Journal of The Korean Digital Architecture Interior Association
    • /
    • v.8 no.1
    • /
    • pp.57-64
    • /
    • 2008
  • There are many problems in present truss-deck slab system for example welding defect, segregation, water leakage, rust and tarnish etc. These problems may be caused by spot welding thin galvanized steel plate and lattice bar. The TOX Joining Systems is to join metal sheets of different material and thickness with and without coating or painting without adding heat or a joining part. Newly developed TOX-deck slab system using non-welding joint is free from above mentioned problems. The objects of this study are suggestion of design strength of TOX joint by experimental and statistical analyses and development of window based program to design the TOX-deck slab system.

  • PDF