• Title/Summary/Keyword: non-response

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Brain Wave Response to Bottle Color of Herbicides and Non-selective Herbicides in Korea (제초제 포장지 색상이 소비자들의 뇌파에 미치는 영향)

  • Kim, Minju;Song, Jieun;Sowndhararajan, Kandhasamy;Kim, Songmun
    • Weed & Turfgrass Science
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    • v.7 no.2
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    • pp.130-139
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    • 2018
  • The colors of packaging of herbicides and non-selective herbicides on the market in Korea are defined as brown and red, respectively, according to the notification of RDA. The present study aimed to understand consumer's electroencephalographic (EEG) response when looking at brown and red colors of herbicide and non-selective herbicide packaging papers. The EEG cap was placed on the scalp of each participant (men and women, 10 to 20 years old) and white (control) - brown - white - red colors were sequentially displayed for 5 seconds using the computer monitor. The EEG was measured and statistical analysis was performed using SPSS. For the brown color of the herbicide, men showed a decrease in concentration and a distracting response due to a decrease in the ratio of mid beta to theta (RMT) and the spectral edge of frequency (SEF90). In women, an increase in the ratio of SMR to theta (RSMT) and the spectral edge frequency 50% of the alpha (ASEF) was observed in different brain regions and these EEG changes may enhance the relaxation, stabilization and awakening states of the brain. For the red color of the non-selective herbicide, ASEF increased psychological stability in men. In women, a decrease in absolute high beta (AHB) may associate with a decrease in attention state of the brain. Overall data of the present study clearly revealed that the colors of two herbicides showed significantly different EEG response and gender difference.

ERCC1 Expression Does Not Predict Survival and Treatment Response in Advanced Stage Non-Small Cell Lung Cancer Cases Treated with Platinum Based Chemotherapy

  • Ozdemir, Ozer;Ozdemir, Pelin;Veral, Ali;Uluer, Hatice;Ozhan, Mustafa Hikmet
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.8
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    • pp.4679-4683
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    • 2013
  • Background: ERCC1 is considered as a promising molecular marker that may predict platinum based chemotherapy response in non small cell lung cancer patients. We therefore investigated whether its expression is indeed associated with clinical outcomes in advanced stage NSCLC patients. Materials and Methods: Pretreatment tumor biopsy samples of 83 stage 3B and 4 non-small cell lung cancer patients treated with platinum based chemotherapy were retrospectively analyzed for immunohistochemical ERCC1 expression. None of the patients received curative surgery or radiotherapy. Results: By calculating H- scores regarding the extent and intensity of immunohistochemical staining of tumor biopsy samples, ERCC1 expression was found to be positive in 50 patients (60.2%). ERCC1 positive and negative groups had no statistically significant differences regarding treatment response, progression free survival and overall survival (respectively p=0.161; p=0.412; p=0.823). Conclusions: In our study we found no association between ERCC1 expression and survival or treatment response. The study has some limitations, such as small sample size and retrospective analysis method. There is need of more knowledge for use of ERCC1 guided chemotherapy regimens in advanced stage NSCLC.

Decreased CRTH2 Expression and Response to Allergen Re-stimulation on Innate Lymphoid Cells in Patients With Allergen-Specific Immunotherapy

  • Mitthamsiri, Wat;Pradubpongsa, Panitan;Sangasapaviliya, Atik;Boonpiyathad, Tadech
    • Allergy, Asthma & Immunology Research
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    • v.10 no.6
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    • pp.662-674
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    • 2018
  • Purpose: Group 2 innate lymphoid cells (ILC2s) have been implicated in the pathogenesis of allergic disease. However, the effect of allergen-specific immunotherapy (AIT) on ILCs remains to be clarified. The aim of this study was to evaluate the levels of ILC subsets in allergic rhinitis (AR) patients in response to house dust mite (HDM)-specific immunotherapy. Methods: We enrolled 37 AR patients undergoing AIT (16 responders and 11 non-responders) for 2 years, 35 HDM AR patients and 28 healthy subjects. Peripheral blood mononuclear cells (PBMCs) were analyzed by flow cytometry to identify ILC subsets. Stimulation of ILC2s with recombinant allergen-specific protein was used to determine ILC2's activation (CD69 expression). Results: Responder AIT patients and healthy subjects had a decreased frequency of circulating ILC2s compared to non-responder AIT and AR patients. Conversely, ILC1s from responder AIT patients and healthy subjects showed increased frequency compared to non-responder AIT and AR patients. The frequency of ILC3s natural cytotoxicity receptor $(NCR)^+$ and $NCR^-$ in responder AIT patients was significantly lower compared to AR patients and healthy subjects. The ILC1: ILC2 proportion in responder AIT patients was similar to that of healthy subjects. PBMCs from patients who were responders to AIT had a significantly lower expression of the activation marker CD69 on ILC2s in response to allergen re-stimulation compared to AR patients, but no difference compared to non-responder AIT patients and healthy subjects. Conclusions: We propose that AIT might affect ILC responses. The activation of ILC2s was reduced in AR patients treated with AIT. Our results indicate that a relative ILC1/ILC2 skewed response is a possible key to successful AIT.

Effect of Listening Biographies on Frequency Following Response Responses of Vocalists, Violinists, and Non-Musicians to Indian Carnatic Music Stimuli

  • J, Prajna Bhat;Krishna, Rajalakshmi
    • Korean Journal of Audiology
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    • v.25 no.3
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    • pp.131-137
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    • 2021
  • Background and Objectives: The current study investigates pitch coding using frequency following response (FFR) among vocalists, violinists, and non-musicians for Indian Carnatic transition music stimuli and assesses whether their listening biographies strengthen their F0 neural encoding for these stimuli. Subjects and Methods: Three participant groups in the age range of 18-45 years were included in the study. The first group of participants consisted of 20 trained Carnatic vocalists, the second group consisted of 13 trained violinists, and the third group consisted of 22 non-musicians. The stimuli consisted of three Indian Carnatic raga notes (/S-R2-G3/), which was sung by a trained vocalist and played by a trained violinist. For the purposes of this study, the two transitions between the notes T1=/S-R2/ and T2=/R2-G3/ were analyzed, and FFRs were recorded binaurally at 80 dB SPL using neuroscan equipment. Results: Overall average responses of the participants were generated. To assess the participants' pitch tracking to the Carnatic music stimuli, stimulus to response correlation (CC), pitch strength (PS), and pitch error (PE) were measured. Results revealed that both the vocalists and violinists had better CC and PS values with lower PE values, as compared to non-musicians, for both vocal and violin T1 and T2 transition stimuli. Between the musician groups, the vocalists were found to perform superiorly to the violinists for both vocal and violin T1 and T2 transition stimuli. Conclusions: Listening biographies strengthened F0 neural coding, with respect to the vocalists for vocal stimulus at the brainstem level. The violinists, on the other hand, did not show such preference.

Effect of Listening Biographies on Frequency Following Response Responses of Vocalists, Violinists, and Non-Musicians to Indian Carnatic Music Stimuli

  • Prajna, Bhat J;Rajalakshmi, Krishna
    • Journal of Audiology & Otology
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    • v.25 no.3
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    • pp.131-137
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    • 2021
  • Background and Objectives: The current study investigates pitch coding using frequency following response (FFR) among vocalists, violinists, and non-musicians for Indian Carnatic transition music stimuli and assesses whether their listening biographies strengthen their F0 neural encoding for these stimuli. Subjects and Methods: Three participant groups in the age range of 18-45 years were included in the study. The first group of participants consisted of 20 trained Carnatic vocalists, the second group consisted of 13 trained violinists, and the third group consisted of 22 non-musicians. The stimuli consisted of three Indian Carnatic raga notes (/S-R2-G3/), which was sung by a trained vocalist and played by a trained violinist. For the purposes of this study, the two transitions between the notes T1=/S-R2/ and T2=/R2-G3/ were analyzed, and FFRs were recorded binaurally at 80 dB SPL using neuroscan equipment. Results: Overall average responses of the participants were generated. To assess the participants' pitch tracking to the Carnatic music stimuli, stimulus to response correlation (CC), pitch strength (PS), and pitch error (PE) were measured. Results revealed that both the vocalists and violinists had better CC and PS values with lower PE values, as compared to non-musicians, for both vocal and violin T1 and T2 transition stimuli. Between the musician groups, the vocalists were found to perform superiorly to the violinists for both vocal and violin T1 and T2 transition stimuli. Conclusions: Listening biographies strengthened F0 neural coding, with respect to the vocalists for vocal stimulus at the brainstem level. The violinists, on the other hand, did not show such preference.

Effects of Design on the Dynamic Response of Reinforced Concrete Slabs (철근 콘크리트 슬래브의 디자인이 동적 거동에 미치는 영향)

  • Oh, Kyung-Yoon;Cho, Jin-Goo;Choi, Soo-Myung;Hong, Chong-Hyun
    • Journal of The Korean Society of Agricultural Engineers
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    • v.49 no.6
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    • pp.47-54
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    • 2007
  • This paper is on the research of the special character of the dynamic response according to a design of the clamped reinforced concrete slab. In this study, the 20-node solid element has been used to analyze the dynamic characteristics of RC slabs with clamped edges. The elasto-visco plastic model for material non-linearity and the smeared crack model have been adopted in the finite element formulation. The design factor, which affect the dynamic response of the reinforced concrete slab, are the steel layer thickness, steel layer depth, steel layout method, steel layout angle and the slab thickness and span ratio. The main purpose of this study was to find out the dynamic response of the reinforced concrete slab according to above variables. The reduction of deflection/thickness ratio appeared less than 2% when the slab thickness between 20 and 21cm. It is desirable that the slab thickness must be above 20-21cm. The reduction ratio of deflection is appeared greatly when the value of the span/thickness ratio is between 25 and 30. In conclusion, the steel layer depth and thickness had a little effect on deflection of the dynamic response, but had no effect on the steel layout angle.

Influence of Analysis Models on Variation of Ground Response during Earthquake (지반응답해석기법의 차이에 의한 지반응답 분산도 평가)

  • Kim, Sung-Ryul;Choi, Jae-Soon;Kim, Soo-Il;Park, Dae-Young;Park, Seong-Yong;Kim, Ki-Poong
    • Proceedings of the Korean Geotechical Society Conference
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    • 2007.09a
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    • pp.317-333
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    • 2007
  • The Round-Robin Test (RRT) for ground response analysis was performed by Division of Geotechnical Earthquake Engineering of Korean Geotechnical Society. This research analyzed the influence of analysis methods on variation of ground response by using the results of this RRT. The analysis methods include equivalent linear analysis, non-linear analysis and effective stress analysis. A total of 5 teams among 12 teams applied two kinds of analysis methods. This research compared the results of these 5 teams and analyzed the variation of the results according to analysis methods. The compared results were shear stress-shear strain relation, transfer function, time history and the response spectrum of ground surface acceleration, peak ground acceleration, peak shear strain and maximum excess pore pressure ratio.

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Dose Motor Inhibition Response Training Using Stop-signal Paradigm Influence Execution and Stop Performance?

  • Son, Sung Min
    • The Journal of Korean Physical Therapy
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    • v.32 no.2
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    • pp.70-74
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    • 2020
  • Purpose: This study examined whether 1) the motor inhibition response as cognitive-behavioral component is learning though a stop signal task using stop-signal paradigm, and 2) whether there is a difference in the learning degree according to imagery training and actual practice training. Methods: Twenty young adults (males: 9, females: 11) volunteered to participate in this study, and were divided randomly into motor imagery training (IT, n=10) and practice training (PT, n=10) groups. The PT group performed an actual practice stop-signal task, while the IT group performed imagery training, which showed a stop-signal task on a monitor of a personal computer. The non-signal reaction time and stop-signal reaction time of both groups were assessed during the stop-signal task. Results: In the non-signal reaction time, there were no significant intra-group and inter-group differences between pre- and post-intervention in both groups (p>0.05). The stop-signal reaction time showed a significant difference in the PT group in the intra-group analysis (p<0.05). On the other hand, there was no significant intra-group difference in the IT group and inter-group difference between pre- and post-intervention (p>0.05). Conclusion: These results showed that the motor inhibition response could be learned through a stop-signal task. Moreover, these findings suggest that actual practice is a more effective method for learning the motor inhibition response.

The Item Analysis of Short Form Sasang Classification Questionnaire for American according to Comparison of Responses between Different Ethnic Groups: Pilot test (미국인용 체질진단지에 의한 인종별 응답차이에 따른 문항분석 : Pilot test)

  • Yoo, Jung-Hee;Shin, Hyun-Sang;Lee, Jun-Hee;Kho, Byung-Hee;Lee, Eui-Ju
    • Journal of Sasang Constitutional Medicine
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    • v.22 no.1
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    • pp.26-33
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    • 2010
  • 1. Objectives: This study has focused on response rates for ethnic groups of American by Short Form Sasang Classification Questionnaire for American (SF SSCQ-A). 2. Methods: By analysing the tendency of the respondents who have been defined ethnic groups and comparing of their answers, the result of their ethnic groups analysis by our questionnaire were examined. Each item response rate on SF_SSCQ-A was analysed between Caucasian and Non-Caucasian respectively. 3. Results and Conclusions: There were the significantly different 11 items between Caucasian and Non-Caucasian. And there were the poor response 26 items; the excessively affirmative 1 item, the excessively negative 18 items, no response 7 items.

A Study on the Conversion Time to Minimize of Transient Response during Inter-Conversion between Control Laws (제어법칙 간 상호 전환 시 과도응답 최소화를 위한 전환시간에 관한 연구)

  • Kim, Chongsup
    • Journal of Aerospace System Engineering
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    • v.9 no.1
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    • pp.12-18
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    • 2015
  • The inter-conversion between different control laws in flight has a lot of risk. The SWM(Switching Mechanism) including logic and stand-by mode is designed to analyze the transient response of aircraft during inter-conversion between different control laws, based on the in-house software for non-real-time and real-time simulation. The SWM applies the fader logic of TFS(Transient Free Switch) to minimize the transient response of an aircraft during the inter-conversion, and applies the reset '0' type of the stand-by mode to prevent surface saturation due to integrator effect in the disengaged flight control law. The transition time is also important to minimize the objectionable transient response in the inter-conversion, as well as the transition control law design. This paper addresses the results of non-real-time simulation for the characteristics of transient response to different transition time to select the adequate transient time, and the real-time pilot evaluation, using SSWM(Software Switching Mechanism) and HSWM(Hardware Switching Mechanism), which is met for Level 1 flying qualities and assures safety of flight.