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Use of Cellulose and Recent Research into Butyrate (섬유소의 이용과 butyrate의 최근 연구)

  • Yeo, Tae Jong;Choi, In Soon;Cho, Kwang Keun
    • Journal of Life Science
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    • v.22 no.11
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    • pp.1571-1586
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    • 2012
  • On earth, there are about 5,400 kinds of mammals, of which about 1,000 kinds are herbivores. Among herbivores, about 250 kinds are known to be ruminants. As for cattle and sheep, which are ruminants, fermentation takes places mainly in their rumen; in contrast, for pigs and men, which are non-ruminants, fermentation takes place mainly in their caecum, colon, and rectum. As for the kind and dominance of rumen microorganisms, Bacteroidetes account for 51% and Firmicutes for 43%. As for the dominance of the large intestine microorganisms in men, Firmicutes account for 65% and Bacteroidetes for 25%. Cell wall components are decomposed by microorganisms, and short chain fatty acids (SCFAs) are generated through fermentation; the ratio of acetate, propionate, and butyrate generate is 60:25:15. Butyrate absorbed through the primary butyrate transporter MCT1 (mono carboxylate transports-1) in the intestines activates such SCFA receptors as GPR43 and GPR41. Butyrate has a strong anti-tumorigenic function. Butyrate is characterized by the fact that it has an effect on many cancer cells, contributes to the coordination of functions in the cells, and induces cancer apoptosis. Butyrate activates caspase but inhibits the activity of HDAC (histone deacetylase), so as to induce apoptosis. In addition, it increases p53 expression, so as to induce cell cycle arrest and apoptosis. Anti-inflammation actions of SCFA include the reduction of IL-8 expression in intestinal epithelial cells, the inhibition of NO synthesis, and the restraint of the activity of NF-${\kappa}B$ (nuclear factor ${\kappa}B$), so as to suppress the occurrence of cancers caused by inflammation. Butyrate plays an important role in maintaining physiological functions of intestinal mucous membranes and is used as a cure for inflammatory bowel disease (IBD).

Deterioration Assessment and Structural‐Reinforcement of Stone Lantern of the Four Guardian Kings in Beopjusa Temple, Boeun (보은 법주사 사천왕석등의 비파괴 훼손도 평가 및 구조보강)

  • Choie, Myoungju;Lee, Myeong Seong;Jun, Yu Gun;Lee, Mi Hye;Kim, Yuri;Ha, Jun Kyeong
    • Journal of Conservation Science
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    • v.33 no.1
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    • pp.25-33
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    • 2017
  • The stone lantern of the four guardian kings in the Beopjusa temple at Boeun was mainly made of biotite granodiorite consisting of porphyritic-textured potassium feldspar and included in ilmenite series. A base stone made of alkali granite was buried, after founded its place during an earlier restoration process. Cracking and break out are noticeable on this object. In addition, discoloration, salt crusting, and epiphytes were observed. The lantern was vulnerable in terms of physical and structural stability caused by cracking in the front and back of the light chamber and in the non-horizontal direction. According to the conservational condition of the stone lantern, structural reinforcement was carried out based on calculations, including those on the position, size, and anchor length of the titanium stiffener. Chemical and biological pollutants were washed off without damage to the surface of the stone material. Oxygenated iron pieces were replaced with titanium. Ethyl silicate was applied to the surface of the lantern for consolidation and smooth drainage.

A Study on Policy Proposal for Senior Start-up and Marketing Strategies for Entrepreneurs (시니어 창업의 정책 제안과 마케팅전략 구축 방안에 관한 연구)

  • Yun, Jeong-Keun
    • Journal of Distribution Science
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    • v.11 no.1
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    • pp.55-63
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    • 2013
  • Purpose - As the members of the baby boomer generation have retired in earnest, the start-up market has received more attention than ever before. According to recent statistical data, an increasing number of entrepreneurs are in their fifties. There has been a continuous increase in promotional materials on small business issues published by start-ups. This means that senior start-ups have increased in number. A number of support systems have been established for youth start-ups, but there are few government support policies in place for the senior start-up market. Thus, this study suggests a number of constructive alternatives from the perspective of government policy and marketing strategy for entrepreneurs, in order to generate competitiveness in the start-up process, through examining the current state of the senior start-up and by diagnosing extant problems. Research design, data, methodology - This study gives a number of options regarding the government's support policies and the securing of competitiveness in order to vitalize senior business start-ups. As for the government's support policies, funding support policy, publicizing business start-up policies, and operating systematic mentoring policies before retirement have all been covered. In particular, in order for senior business start-ups to become competitive, development through mutual relations with diverse policies is urgently needed. The aging population is becoming an issue in Korea, so businesses for the aged, and the creation of jobs for these people, will become a social issue. Senior business start-ups are playing an important role in expanding enterprise productivity, in addition to enhancing national competitiveness. Expanding senior business start-ups is important, because they also serve to expand the national infrastructure. Productivity increase through continuous expansion is thus recommended. Results - In order to expand the competitiveness of business start-ups, marketing-related observations and learning in regard to customers are necessary for the baby boomer generation, and competitiveness for seniors is urgently needed. Conclusions - Studies on the business start-up policies for the domestic baby boomer generation are almost non-existent, and systematic studies on small businesses are necessary. Only the government is providing statistical studies for small businesses, and such research remains at a general level for entrepreneurs. Therefore, a support system that can actually assist entrepreneurs is essential. Continuous business start-up studies with respect to the baby boomers should be vitalized, to invigorate studies on competition. In order to supplement and strengthen foundational support, senior business start-ups must develop various competitive capabilities with a focus on the customer. The government and the various stakeholder agencies and organizations involved with start-up businesses must find ways to offer support to founders. Such support should include access to knowledge and legal and consultancy services in order to incubate the rapid increase in start-ups founded by seniors. Government support projects should be expanded to meet this end.

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A Study on the Expected Effect of Mobile Prepaid Payment for the Activation of Food Waste Volume-Rate System (음식물 종량제 활성화를 위한 모바일 선불결제 적용에 따른 기대효과 연구)

  • Kim, YongIl;Kim, SeungCheon
    • Journal of Convergence for Information Technology
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    • v.10 no.11
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    • pp.47-54
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    • 2020
  • This study proposes an NFC-based payment system that considers user convenience while expanding the existing payment method for RFID-based individual food and logistics waste equipment. In line with this trend, I proposed to apply NFC to the existing RFID-based food meter to release the food in the meantime and to address the problem of re-carrying due to card loss, card not possessed, and non-filling, and the question that could not be identified by various cumbersome procedures. NFC's function alone has been certified for its convenience, which led to its introduction and research in the period of time. Of course, we need to negotiate fees with the transportation card company, but if we see a market share related to transportation card soon, we think smooth negotiations will take place. NFC method will be expanded to all phones with iPhone NFC opening. Therefore, in the next study, we intend to apply the payment system in NFC by linking with local currency, mobile vouchers, and card companies, which are being paid as respective payment means according to the recent emergency support system for COVID-19.

A Result of Field Survey for Ergonomic Work Risk Factors in General Hospital (의료업종의 작업위험요인에 대한 실태조사 결과)

  • Kim, Jin-Young;Kim, Yeong-Mee;Kim, Day-Sung;Im, Heung-Jae;Kim, Jeung-Ho;Kang, Seong-Kyu
    • Journal of the Ergonomics Society of Korea
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    • v.26 no.3
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    • pp.91-100
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    • 2007
  • The purposes of this research are to survey work-related risk factors of musculoskeletal disorders(MSDs) in various departments and tasks at general hospitals in non-manufacturing sectors, and to use basic data derived from the survey results in preventing work-related MSDs in hospital workers. Investigation started in March of 2006 and continued for 6 months in 220 general hospitals at Seoul, Incheon, Kyeongi, and Kangwon area. Investigators visited and interviewed workers in hospitals to identify the presence of tasks of musculoskeletal burden, the investigation results of ergonomic risk factors required by the Occupational Safety and Health Law, statistical analysis from questionnaire for musculoskeletal symptoms, and major departments and tasks that have such risk factors. Twenty-seven percents of hospitals finished the investigation of ergonomic risk factors, and 69% did not do the investigation while remained 4% did not have such factors in their hospitals. The rank order of major departments that had such musculoskeletal burdens was kitchen rooms of 143, managing departments/computer rooms/dispensaries of 137, physical treatment rooms of 109, nursing departments of 96, radiological and clinical laboratories of 63. Eighteen hospitals that did not hold legal duties by the section 148 of labor minister decree practiced prevention programs of MSDs according to the labor-management cooperation. Nursing departments ranked in the first place for the numbers of musculoskeletal symptoms of 438. Managing departments/computer rooms/dispensaries, kitchen rooms, and medical treatment departments held 127, 52 and 45 symptoms, respectively. The magnitude order of physical symptom areas followed shoulder of 185, backs and waist of 166, hand wrists of 120, necks of 110, and legs/feet of 106. The departments and jobs that had major work-related ergonomic risks were patient transporting, central supplying, patient nursing (moving patients into wheel-chairs, changing of patient posture and sheet alteration), manual transporting, operation, and managing/computer departments.

A Study on the Nosocomial Infection in One Burn Unit (일 화상 치료실에 입원한 화상환자의 감염실태조사)

  • 김정애
    • Journal of Korean Academy of Nursing
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    • v.17 no.3
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    • pp.227-240
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    • 1987
  • Infection has assumed increased importance as a cause of death among thermally injured individuals. Decreased treatment effectiveness and an increase in mortality are the hallmarks of nosocomial infection. Infection control is a monumental task that must be achieved to reduce mortalities. This was a retrospective study to survey the epidemiological features of nosocomial infections in a burn unit and to identify the possibilities for infection control. During the past 6 year 2 month period from July, 1981 to August, 1987, 306 burn patients were treated in the burn unit of university hospital. Among of these, 290 cases were the subjects of this study. The data were collected from the patients' records after discharge. All data collected were analyzed using percent, x$^2$-test, t-test with SPSS program. The results of this study are summariged as follows: 1) Infection rate was 40%. According to site, there were 67 cases of wound infection, 60 cases of post-operative skin graft infection, 20 cases of septicemia and 20 cases of donor site infection. As far as the burn size was concerned, the infection rate for patients whose burn size ranged 61 to 70%, was shown to be 100%, followed by the infection rate of 93.8%, for patients whose burn size ranged from 41~50%. As far as the period of time over which the infection developed, 5 to 7 days showed the highest frequency. Further infection was the main cause of deaths and complications. 2) Based upon the results obained by comparing the general characteristics, between a hospital infection-group and non-hospital infection group, there was a significant defference according to age, the time of the year when the accident happened, the place of accident or length of hospital-admission. And according to the result obtained by comparing the general characteristics of the burn, there was a significant difference according to burn size, burn depth, burn type, and burn site. And also based upon the result obtained by comparing the two groups according to method of treatment, there was a significant difference according to the use of antibiotics and to the type of wound-treatment, and for the 8 different binds of treatment related to infection, there was a significant difference for all. In conclusion, age, length of hospital-admission, burn size, burn type, burn site, burn depth, type of woundtreatment and the 8 different binds of treatment, which are related to burns, were shown to be the factors which affect the infection rate in burn patients.

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TREATMENT OF COMPOSITE RESIN RESTORATION WITH THE AIR ABRASIVE TECHNIQUE (Air abrasive technique을 이용한 복합레진 수복 증례)

  • Lee, Chang-Woo;Jang, Ki-Taeg;Lee, Sang-Hoon;Hahn, Se-Hyun
    • Journal of the korean academy of Pediatric Dentistry
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    • v.24 no.4
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    • pp.763-770
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    • 1997
  • The air abrasive technique is a non-mechanical method by which teeth are treated before restoration and stains and calculi are removed from tooth surfaces using the kinetic energy of small particles. The air abrasive technique in dentistry was first introduced in the 1950's with as instrument called 'Airdent'. But, as the main restorative materials of the period were amalgam and gold, and the instrument's inability to control the flow of particles caused the particles to be spread throughout the clinics, widespread use was not possible. In the 1990's, as these techincal problems were solved and more interest in new restorative materials rose in an effort to preserve sound tooth structure, new developements took place in instruments related to the air abrasive technique. The air abrasive technique produces less pressure, vibration and heat that might cause patient discomfort and facilitates the preservation of sound tooth structure. It also reduces the need for anesthesia and is less harmful to the pulp. Other advantages include increase in dentin bonding strength of composite resin, lower possibility of saliva contamination and maintenance of a dry field. But there is not direct contact between the nozzle and the tooth, the operator cannot use his or her tactile sense and must rely solely upon visual input. Other disadvantages are: the tooth preparation depends on the operator's ability; alpha-alumina particles, after bouncing off the tooth surface, cause damage to dental mirrors; the equipment is expensive and takes up a certain amount of space in the clinic. The author conducted case report using the air abrasive technique on patient visiting the Department of Pediatric Dentistry at Seoul National University Dental Hospital and arrived at the following conclusions. 1. The tooth preparation capability of different air abrasive devices varied widely among manufacturers. 2. It was more effective in treating early caries lesions and stains compared to lesions where caries had already progressed to produce soft dentin. 3. The cold stream and noise caused by the evacuation system was a major cause of discomfort to pediatric patients. 4. As there is no direct contact with tooth surface when using the air abrasive technique for tooth preparation, considerable experience and skill is required for proper tooth preparation.

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A Study on the Cognitive Factors of the Space in Pulkuksa Temple at Tohamsan Mountain (토함산 불국사의 공간인식특성에 관한 연구)

  • Huh, Joon;Kim, Yong-Ki;Hong, Kwang-Pyo
    • Journal of the Korean Institute of Landscape Architecture
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    • v.26 no.4
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    • pp.125-134
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    • 1999
  • To analyze in detail the cognitive factors in the sense of place in Korea traditional temples and their occurrence and significance, the questionaring was conducted about the actual condition of visitor's using of and preference for Pulkuksa Temple as an object of the investigation. The result from the analysis of the visitors' sense of respective factors forming the image of the temple is as follows: 1. While the male visitors for outnumbered the female, the female visitors are more satisfied with the senses of the temple than male. The younger visitors are larger in number while the older visitors have the more satisfaction. It took the largest number of the visitors at least three hours to come to the temple. The most numerous are the visitors who came to the temple. The most numerous are the visitors who came to the temple by their own cars. The visitors are coming not only from the Kyunsang Provinces but from all over the country and they made a family trip to the temple. 2. 86 people among the questionees replied that the Tower stands best for Pulkuksa temple. The second largest number of the questionees replied that the main sanctuary does. The third largest number of the questionees replied that the natural environment does. 3. The visitors who came to the temple for sightseeing showed their highest preferences for each of the main sanctuary and the tower. The buddhist visitors also showed the same tendency as non Buddhist ones in their preference. 4. On the whole, the space factors such as buildings and scenes which represent Pulkuksa Temple are the towers such as Sukka Tower and Tabo Tower, the sanctuary buildings such as main sanctuary, the natural scenery such as Toham Mountain, and the steps such as Chungwun-Kyo and Paekwun-Kyo. 5. The potential factors to explain the structural characteristics of the scenery in Pulkuksa Temple are revealed to be a factor of overall valuation, of orderliness, of individuality and of comfortableness, through hypothetical. T.V was 54.1% and the orderliness of Sukkatap was highly evaluated in factor score analysis.

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Factors influencing the return of spontaneous circulation of patients with out-of-hospital cardiac arrest (병원외 심정지 환자의 자발적 순환 회복에 영향을 미치는 요인)

  • Park, Il-Su;Kim, Eun-Ju;Sohn, Hae-Sook;Kang, Sung-Hong
    • Journal of Digital Convergence
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    • v.11 no.9
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    • pp.229-238
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    • 2013
  • Out-of-hospital cardiac arrest is a major public health problem in Korea. The survival rate to discharge remains at approximately 3.5% and only 1% have good neurological function. To increase the survival rate, prehospital care should restore spontaneous circulation. The purpose of this study was to analyze the factors associated with return of spontaneous circulation(ROSC) after out-of-hospital cardiac arrest. Data used for this study were collected from KCDC Out-of-Hospital Cardiac Arrest Surveillance 2009. As for the results of decision tree analysis, it is clear that prehospital CPR, cardiac arrest witness, activity, past history(cancer/heart disease/stroke), place, bystander CPR, response time, age, etc are significant contributing factors in ROSC. Among 16 cardiac arrest types from decision tree classification, the ROSC rate of type 1 is the highest(29.6%). Also notable is the fact that bystander CPR was strongly correlated with ROSC of patents with cardiac arrest occurring in non-public places. Community resources should be concentrated on increasing bystander CPR and early prehospital emergency care.

Evaluation of the Forest Bird Community by using a Sound Recording System -Verification for the Avifauna evaluation in the non-breeding season -

  • Yoo, Seung-Hwa;Han, Hyun-Jin;Kim, Dong-Won;Joo, Woo-Young
    • Korean Journal of Environment and Ecology
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    • v.29 no.2
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    • pp.174-183
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    • 2015
  • We have conducted a verification test of correlation between bird community indices and bird sound recording results in order to use the equipment which deals with the automatic sound collecting system, the song meter. The study areas include four sites which are Gombaeryoung and Zochimryoung in Jeombongsan Mountain and Jookryoung and Gochiryoung in Sobaeksan National Park. We collected the bird sound data five times using a sound recorder and field survey results in the same place of the study site. As a result of the sound recording from the field survey, the species recorded by three researchers of sound analyst include common resident species or species which have a relatively conspicuous call and song. On the contrary, the species recorded by only one researcher are a relatively rare or inconspicuous species or was familiar with the personal experiences of each researcher. The number of species recorded by only one researcher totaled fourteen species (36.8 %), and that of two researchers totaled twelve species (31.6 %), and that of three researchers totaled twelve species (31.6 %). The correlations of the number of species among three researchers was not significant in some results, but the sum or maximum count of the number of species was useful to estimate a significant correlation between the result of researchers and the indices of field surveys. As a result of correlation analysis by using sound recordings, the maximum number of species among the three researchers significantly correlated with the number of species, the species diversity index and the species abundance index in the field survey at the same site, however it did not correlate with the number of individuals and species evenness index. As a result of sound analysis collected from the stationary sound recording system; song meter, the number of frequencies in bird songs and calls correlated with the number of species in the field survey at the same site. The number of calls and songs decreased as time went by. Finally, we could test the active time range and change the activity strength by using a sound recording system. In particular, that sound recording system is able to collect data in same time and site, so it is expected so that the equipment not only replenish a shortage of researchers and survey periods in field research in a short term monitoring survey, but also be able to acquire statistical objectivity.