• Asian Pacific Journal of Cancer Prevention
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• v.15 no.14
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• pp.5901-5908
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• 2014

Background: Data from BreastScreen Australia Screening and Assessment Services (SAS) for 2002-2010 were analysed to determine whether some SAS characteristics were more conducive that others to high screening performance, as indicated by high priority performance indicators and standards. Materials And Methods: Indicators investigated related to: numbers of benign open biopsies, screen-detected invasive cancers, and interval cancers, and wait times between screening and assessment. Multivariate Poisson regression was undertaken using as candidate predictors of performance, SAS size (screening volume), urban or rural location, year of screening, accreditation status, and percentages of clients from culturally and linguistically diverse backgrounds, rural and remote areas, and socio-economically disadvantaged areas. Results: Performance standards for benign biopsies and invasive cancer detection were uniformly met irrespective of SAS location and size. The interval cancer standard was also met, except in 2003 when the 95% confidence interval of the rate still incorporated the national standard. Performance indicators improved over time for: benign open biopsy for second or subsequent screening rounds; rates of invasive breast cancer detection for second or subsequent screening rounds; and rates of small cancer detection. No differences were found over time in interval cancer rates. Interval cancer rates did not differ between non-metropolitan and metropolitan SAS, although state-wide SAS had lower rates. The standard for wait time between screening and assessment (being assessed ${\leq}28$ days) was mostly unmet and this applied in particular to SAS with high percentages of culturally and linguistically diverse women in their screening populations. Conclusions: Gains in performance were observed, and all performance standards were met irrespective of SAS characteristics, except wait times to assessment. Additional descriptive data should be collected on SAS characteristics, and their associations with favourable screening performance, as these may be important when deciding on SAS design

• Journal of Korean Academy of Nursing
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• v.42 no.3
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• pp.424-433
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• 2012

Purpose: To investigate the accuracy, precision and validity of fever detection of tympanic membrane (TM), temporal artery (TA) and axillary temperature (AT) compared with pulmonary artery temperature (PA). Methods: Repeated-measures design was conducted for one year on 83 adult cardiac care unit patients with pulmonary artery catheters after open heart surgery. Sequential temperature measurements were taken three times at 20-minute intervals. Accuracy, precision, repeatability, and validity of fever detection were analyzed. Results: Mean pulmonary artery temperature was $37.04^{\circ}C$ (SD $0.70^{\circ}C$). The mean (SD) offsets from PA, with the mean reflecting accuracy and SD reflecting precision, were $-1.31^{\circ}C$ ($0.75^{\circ}C$) for TA, $-0.20^{\circ}C$ ($0.24^{\circ}C$) for TM, and $-0.97^{\circ}C$ ($0.64^{\circ}C$) for AT. Percentage of pairs with differences within ${\pm}0.5^{\circ}C$ was 9.6% for TA, 19.7% for AT, and 91.6% for TM. Repeated measurements with all three methods had mean SD values within $0.04^{\circ}C$. Sensitivity, specificity, and positive and negative predictive values of tympanic measurements were 0.76, 1.0, and 1.0, and 0.90, respectively. Conclusion: Results show that TM best reflects PA, and is most consistent, accurate, and precise. AT tends to underestimate PA, and TA is least accurate and precise. Therefore tympanic membrane measurement is a reliable alternative to other non-invasive methods of measuring temperatures.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.5
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• pp.3001-3003
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• 2013

Objective: Spleen tyrosine kinase (Syk) is closely related to tumor invasion and metastasis, and has been shown to have potential inhibitory effects in tumors. In this study, we constructed a eukaryotic expression vector for Syk and analyzed its effects on invasive ability of the A549 non-small cell lung cancer cell line in vitro. Methods: A fragment of Syk was obtained by RT-PCR from human lung cancer cells and cloned into the expression vector pLNCXSyk. After restriction endonuclease digestion, PCR and DNA sequencing confirmation, the recombinant Syk expression plasmid was transfected into A549 human lung cancer cells using lipofectamine protocols. After selection, the cells stably expressed Syk. Detection of Syk expression of the cells by RT-PCR, and invasive ability were examined. Results: The eukaryotic expression plamid pLNCXSyk was constructed and expressed stably in the A549 human lung cancer cells. The RT-PCR results showed that Syk mRNA expression was upregulated significantly (P<0.05). Lower invasion through a basal membrane were apparent after transfection (P<0.05). Conclusions: A eukaryotic expression plasmid to cause Syk expression in lung cancer cells can obviously inhibit their invasive ability in vitro.

• Journal of Sensor Science and Technology
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• v.32 no.4
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• pp.219-222
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• 2023

Partial discharges (PD) have long been recognized as a major contributing factor to catastrophic failures in high-power equipment. As the demand for high voltage direct current (HVDC) facilities continues to rise, the significance of on-line and real-time monitoring of PD becomes increasingly prominent. In this study, we have designed, fabricated, and characterized a highly sensitive and cost-effective PD sensor comprising a pair of copper electrodes with different arc lengths. The key advantage of our sensor is its non-invasive nature, as it can be installed at any location along the entire power cable without requiring structural modifications. In contrast, conventional PD sensors are typically limited to installation at cable terminals or insulation joint boxes, often necessitating invasive alterations. Our PD sensor demonstrates exceptional accuracy in estimating PD location, with a success rate exceeding 95% in the straight sections of the power cable and surpassing 89% in curved sections. These remarkable characteristics indicate its high potential for realtime and on-line detection of PD.

• 한국생물공학회:학술대회논문집
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• 2000.11a
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• pp.264-265
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• 2000

Helicobacter pylori(H. pylori) is the causative agent of chronic gastritis and the single most important factor in peptic ulcer disease, however, the pathogenetic mechanisms underlying H, pylori infection are not well understood. Futhermore, there is a strong association between H. pylori infection and gastric cancer. Various diagnostic methods for detecting H. pylori infection are available. These can be divided into invasive methods, requiring endoscopy, and non-invasive tests, mainly 13C-urea breath tests and serologic detection of antibodies. Rapid urease test is the most recommendable endoscopic test for the diagnosis of H. pylori infection, presently. CLO test kit is the represent of rapid urease test kits. The principles of CLO test kit is that hydrolysis of urea by urease Is detected by a dye indicators showing a color change. Our device is used same principle but we improved the reaction time is more faster and positive color change is more distinctive from the color of the negative specimen. So, this kit is more reliable because it response faster and accuracy.

• Journal of Computing Science and Engineering
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• v.8 no.2
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• pp.87-93
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• 2014

Coronary artery disease (CAD) is currently a prevalent disease from which many people suffer. Early detection and treatment could reduce the risk of heart attack. Currently, the golden standard for the diagnosis of CAD is angiography, which is an invasive procedure. In this article, we propose an algorithm that uses data mining techniques, a fuzzy expert system, and the imperialist competitive algorithm (ICA), to make CAD diagnosis by a non-invasive procedure. The ICA is used to adjust the fuzzy membership functions. The proposed method has been evaluated with the Cleveland and Hungarian datasets. The advantage of this method, compared with others, is the interpretability. The accuracy of the proposed method is 94.92% by 11 rules, and the average length of 4. To compare the colonial competitive algorithm with other metaheuristic algorithms, the proposed method has been implemented with the particle swarm optimization (PSO) algorithm. The results indicate that the colonial competition algorithm is more efficient than the PSO algorithm.

• Investigative Magnetic Resonance Imaging
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• v.23 no.3
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• pp.259-263
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• 2019

Although many imaging modalities can play some roles in the diagnosis of vertebral artery dissection (VAD), digital subtraction angiography (DSA) remains the gold standard method, with the highest detection rate and ability to assist in planning for endovascular treatment. However, this tool is often avoided in children because its invasive nature and it exposes them to radiation. High resolution magnetic resonance imaging (HR-MRI) have been suggested to be a reliable and non-invasive alternative, but it has never been discussed in children in whom vertebral artery dissection is a rare condition. In this report, we evaluate a case of a 2-year-old child who initially presented with cerebellar symptoms, and was early diagnosed with vertebral artery dissection using HR- MRI and was successfully treated.

• Proceedings of the Optical Society of Korea Conference
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• 2002.07a
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• pp.252-253
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• 2002

원적외선 영역에서 혈중성분들의 분광 특성이 존재함이 확인되면서 이 영역의 빛을 이용한 혈중 성분의 정량 분석을 통한 진단기술 개발이 활발히 진행되고 있다1). 특히 원적외선 영역에서 특정 파장에서의 반응성을 이용한 여러 방법들 중 photo-Acoustic을 이용한 방법이 여러 가지로 연구되어지고 있다. (2) 현재 수용액 상태의 혈중 성분들의 원적외선 분광 특성을 연구하였으며, 이를 이용한 혼합 성분들의 흡수 spectrum 정량-정성 분석이 가능하며, 이러한 특성을 이용하여 non-invasive로 이용 가능한 분광법을 연구 진행 중이다. (중략)

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2015.11a
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• pp.183-183
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• 2015

Arc in plasma processing chamber results in high current discharge marks and particles on wafers, but it is hard to identify or observe it during the proc ess. In this paper, we report the observations of plasma arc s during various plasma proc esses through a non-invasive optic al plasma monitoring system (OPMS) devised for the in-situ detec tion of abnormal discharge.

• Proceedings of the Korean Nuclear Society Conference
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• 2005.05a
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• pp.275-276
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• 2005