• 대한신경집중치료학회지
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• 제7권2호
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• pp.104-110
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• 2014

Background: Cefepime is a fourth-generation cephalosporin widely used for empiric treatment of severe infections. Neurotoxicity by cefepime have been reported due to γ-aminobutyric acid A receptor inhibition or other mechanisms. The aim of this study was to evaluate the risk factors for cefepime-induced neurotoxicity between group showing cefepime-induced neurotoxicity and group without neurotoxicity. Methods: From Jan 2005 to June 2010, a total of 2,461 patients (older than 20) who used cefepime were considered in this study. We compared patients who developed cefepime-induced neurotoxicity (patient group, n=21) to patients who had no cefepime-induced neurotoxicity (control group, n=31). We analyzed demographic, underlying diseases, and metabolic parameters before cefepime treatment and during cefepime treatment between the two groups. Statistical analysis was performed using SPSS 18 software. Results: Of the total 2461 patients, 21 (0.85%) were diagnosed with cefepime-induced neurotoxicity. Impaired glomerular filtration rate (GFR at 15-30 ml/min) before cefepime use were significantly (P<0.05) higher risk for developing cefepime-induced neurotoxicity in patient group compared to that in the control group. Age, sex, and other metabolic parameters except GFR before and during, usage of cefepime did not show any statistical difference between the two groups. Conclusion: The present study revealed that cefepime-induced neurotoxicity was prone to develop in patients with impaired renal function before cefepime usage.

• Asian Pacific Journal of Cancer Prevention
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• 제15권9호
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• pp.4049-4054
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• 2014

Background: Race and ethnicity are significant factors in predicting survival time of breast cancer patients. In this study, we applied advanced statistical methods to predict the survival of White non-Hispanic female breast cancer patients, who were diagnosed between the years 1973 and 2009 in the United States (U.S.). Materials and Methods: Demographic data from the Surveillance Epidemiology and End Results (SEER) database were used for the purpose of this study. Nine states were randomly selected from 12 U.S. cancer registries. A stratified random sampling method was used to select 2,000 female breast cancer patients from these nine states. We compared four types of advanced statistical probability models to identify the best-fit model for the White non-Hispanic female breast cancer survival data. Three model building criterion were used to measure and compare goodness of fit of the models. These include Akaike Information Criteria (AIC), Bayesian Information Criteria (BIC), and Deviance Information Criteria (DIC). In addition, we used a novel Bayesian method and the Markov Chain Monte Carlo technique to determine the posterior density function of the parameters. After evaluating the model parameters, we selected the model having the lowest DIC value. Using this Bayesian method, we derived the predictive survival density for future survival time and its related inferences. Results: The analytical sample of White non-Hispanic women included 2,000 breast cancer cases from the SEER database (1973-2009). The majority of cases were married (55.2%), the mean age of diagnosis was 63.61 years (SD = 14.24) and the mean survival time was 84 months (SD = 35.01). After comparing the four statistical models, results suggested that the exponentiated Weibull model (DIC= 19818.220) was a better fit for White non-Hispanic females' breast cancer survival data. This model predicted the survival times (in months) for White non-Hispanic women after implementation of precise estimates of the model parameters. Conclusions: By using modern model building criteria, we determined that the data best fit the exponentiated Weibull model. We incorporated precise estimates of the parameter into the predictive model and evaluated the survival inference for the White non-Hispanic female population. This method of analysis will assist researchers in making scientific and clinical conclusions when assessing survival time of breast cancer patients.

• 한국산학기술학회논문지
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• 제13권7호
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• pp.3065-3073
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• 2012

본 연구는 대구지역 여성들을 대상으로 웰빙 행동의 특성을 파악하고 이에 영향을 미치는 사회 인구학적 변인에 따른 웰빙 수준을 분석하여 이러한 요인들이 웰빙 행동에 어떠한 영향을 미치는지를 파악하고자 하였다. 320명의 여성들을 대상으로 설문조사를 실시하였으며, 사회 인구학적 변인에 따른 웰빙 수준, 웰빙 행동과 웰빙 행동에 영향을 미치는 요인을 검증하기 위해 t-test, ANOVA, 다중회귀분석을 실시하였다. 본 연구의 주요 결과를 요약하면 다음과 같다. 학력이 높을수록 웰빙 수준이 높은 것을 알 수 있었고, 직업에서는 교육 상담직과 자영업이, 월 소득은 높을수록, 자기관리 지출비용이 많고 건강하다고 생각하는 여성일수록, 음주량에서는 주 1~2회 섭취하는 여성들이 웰빙 수준이 높은 것으로 나타났다. 웰빙 행동에 영향을 미치는 요인을 분석한 결과 연령이 높을수록, 학력이 높을수록, 자기관리 지출비용이 많을수록, 흡연을 하지 않을수록 웰빙 행동을 많이 하는 것으로 나타났다. 웰빙에 대한 가치, 신념 등을 확고히 하여 여성들의 정체성을 유지하고 건전한 웰빙 인식을 고취시켜 건전한 웰빙 행동으로 유도해야 된다고 생각된다.

• 한국사회복지학
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• 제65권3호
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• pp.29-52
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• 2013

본 연구는 2009년 통계청 생활시간조사자료를 이용하여 연령과 사회구조적 층화에 따른 시간 배분 경향을 분석하였다. 중고령자의 생활시간배분 경향을 총체적으로 파악하기 위해 유급노동과 더불어 가사활동, 사회참여, 여가시간을 포괄적으로 분석하였으며, 생활시간 배분경향이 연령과 사회구조적 층화의 상호작용에 따라 달라지는지 확인하기 위해 토빗회귀분석을 실시하였다. 분석결과, 중고령자의 시간배분 경향은 유급노동시간의 점진적 감소와 가사노동 및 수동적 여가의 증대로 나타났다. 그러나 이러한 경향은 사회구조적 층화에 따라 상이하게 분화되고 있었다. 교육수준이 높을수록, 무배우자가 유배우자에 비해, 연령증가에 따른 유급노동시간의 감소가 급격히 나타나고 여가시간은 가파르게 증가하는 경향을 보였다. 농가는 비농가에 비해 연령에 따른 노동시간 감소가 완만하게 나타났으며, 여성은 남성에 비해 연령증가에 따라 가사와 돌봄활동을 감소시켰지만, 생산활동시간 총량은 크게 변하지 않았다. 이상의 분석결과를 바탕으로 본 연구에서는 효과적인 고령화 정책을 마련하기 위해 고령자를 단일집단으로 간주하는 획일적인 접근을 탈피하고, 고령화라는 변화를 겪는 이들이 놓여있는 다양한 사회구조적 요인을 반영할 필요성이 있음을 제언하였다.

• 한국산학기술학회논문지
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• 제19권12호
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• pp.584-591
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• 2018

본 연구는 우리나라 100세 이상 고령자의 인지기능장애 수준을 알아보고 그의 관련요인을 규명해 보고자 시도하였다. 연구대상은 2016년부터 2017년까지의 기간 동안에 국민건강보험공단에서 시행하는 건강검진 및 장기요양 인정조사를 받은 주민등록상의 100세 이상 고령자 268명(남성 132명, 여성 136명)으로 하였다. 연구결과, 조사대상 100세 이상 고령자의 인지기능장애수준은 남성보다 여성에서(p=0.000), 혼자 산다는 군보다 배우자나 자녀와 함께 산다는 군에서(p=0.019), 가정의 경제 상태가 낮을수록(p=0.001), 비만도가 낮을수록(p=0.000), 비흡연군보다 흡연군에서(p=0.000), 비음주군보다 음주군에서(p=0.013), 규칙적인 운동을 한다는 군보다 하지 않는다는 군에서(p=0.020)에서 유의하게 낮았다. 조사대상 100세 이상 고령자의 확정적 인지기능장애가 나타날 위험비는 남성보다 여성(ORs=9.85, 95% CI=2.88~33.59)에서 유의하게 증가하였고, 저체중군보다 비만군(ORs=0.25, 95% CI=0.07~0.86)에서, 흡연군보다 비흡연군(ORs=0.30, 95% CI=0.10~0.83)에서 유의하게 감소하였다. 조사대상 100세 이상 고령자의 인지기능장애에 영향을 미치는 요인으로는 성, 거주상태, 경제상태, BMI, 흡연상태가 유의한 변수로 선정되었다. 이상과 같은 연구결과를 보면, 조사대상 100세 이상 고령자의 인지기능장애 수준은 여러 인구사회학적 및 건강관련행위특성 변수에 따라 유의한 차이를 보이고 있었다. 특히 흡연, 음주 및 규칙적인 운동 등과 같은 건강관련행위특성이 좋지 않은 군에서 인지기능 수준이 저하됨을 시사하고 있다.

• 한국심리학회지:여성
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• 제17권3호
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• pp.435-456
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• 2012

본 연구는 결혼이주여성의 가족상담 필요성 인식에 미치는 요인들을 파악함으로써, 결혼이주여성과 다문화가족을 위한 가족상담의 지원 방향을 제시하는 데 목적이 있다. 이를 위해 보건복지부에서 실시한 2010년도 전국다문화실태조사자료를 사용하여 결혼이주여성 총 58,072명을 대상으로, 사회인구학적 변인, 한국어 능력, 사회적 지지, 가족관계 만족도, 가족상담 경험 유무를 중심으로 가족상담 필요성 인식에 미치는 요인들을 살펴보았다. 본 연구의 결과는 다음과 같다. 첫째, 결혼이주여성은 가족상담에 대해 보통 수준으로 필요성을 인식하고 있었으며, 한국어 능력 수준도 중간 수준이었다. 사회적 지지원이 한국인, 모국인 모두 2명을 넘지 않았고, 배우자, 자녀, 시부모와의 관계에 대해서는 전반적으로 만족하고 있었다. 둘째, 결혼이주여성의 출신국가에 따른 가족상담 필요성 인식에 대한 차이가 나타났다. 조선족, 중국, 일본 출신의 여성들은 가족상담 필요성 인식이 낮았고, 베트남, 필리핀, 캄보디아 등 동남아 출신 여성들은 가족상담 필요성에 대한 인식이 높게 나타났다. 셋째, 결혼이주여성들은 연령이 어리고, 본인의 학력이 높고, 배우자의 학력이 낮고, 결혼지속년수가 짧고, 자녀가 많고, 배우자 부모와 동거하고 있고, 스스로 배우자를 만나지 않았을 경우, 가족상담에 대한 필요성을 더 높게 인식하고 있었다. 또한, 한국어 능력이 낮고, 사회적 지지원으로 한국인의 수가 적고, 배우자와의 관계에 불만족하고, 자녀와의 관계에 만족하고, 상담에 대한 경험이 있는 경우 가족상담 필요성에 대한 인식이 높아지는 것으로 나타났다.

• 대한가정학회지
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• 제35권1호
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• pp.357-372
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• 1997

The purpose of this study was to 1) segment female adolescent consumers into consumer groups displaying different consumer decision-making styles 2) to determine the consumer characteristics(clothing involvement information search store patronage and demographic variables) that related to each consumer segment and 3) to identify the interrelationship between the consumer characteristics. Decision-making styles were measured by 32 seven-point Likert type scales adapted from Sproles & Kendall and Shim & Kot A total of 78 statements dealing with three aspects of consumer characteristics was adapted from previous research. Data were collected from 567 2nd grade female middle and high school students in Seoul via self-administered questionnaires. and were analysed by frequency factor analysis ANOVA cluster analysis χ2 -test and Duncan's multiple range test. The results of this study were as follows: As a results of cluster analysis and ANOVA on seven factors of desion-making styles(1. brand-consiousness 2. novelty/fashion-consciousness 3. recreational/hedonis-tic orientation, 4. impulsive/carelessness, 5. price-consciousness/value-for-money, 6. perfectionism/high quality orientation 7. habitual/brand-royal consciousness) three consumer groups were identified and labeled as puality-oriented/non-utlitarian shoppers price-oriented shoppers and apathetic shoppers. Quality-oriented/non-utilitarian shoppers showed the highest clothing involvement scores of all aspects the highest consumer knowledge/experience most active ongoing information search and prepurchase information search. They preferred department store and franchise store for apparel shopping and considered service/reliability atmosphere variety of goods as important store attributes, Price-oriented shoppers showed prepurchase information search and planned purchase behavior actively. They preferred factory outlet store specialty stre and considered price very important as store attributes. Apathetic shoppers showed the lowest scores of all aspects of clothing involvement and most passive behavior in information search activities except showing the highest planned purchase. They preferred regional markets.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7473-7478
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• 2015

Background: Kermanshahi oil is one the most favorable oils in Iran especially in Kermanshah province. We aimed to evaluate the role of usual intake of Kermanshahi oil and other kinds of dietary fats as well as different meats, vegetables and fruits, carbohydrates, cereals, grains, sweets, candy and lifestyle habits in risk of breast cancer. Materials and Methods: A case-control study with 47 consecutive, newly diagnosed premenopausal breast-cancer patients and 105 age and socioeconomic matched healthy women was conducted from 2013-2014 in Imam Reza hospital of Kermanshah using a standardized, validated questionnaire assessing various anthropometric, socio-demographic, lifestyle and dietary characteristics. Results: Kermanshahi oil intake was associated with a 2.1-fold (OR=2.123, 95% CI 1.332-3.38) (p=0.002) higher likelihood of having breast cancer, while daily intake of other solid animal fats also increased the likelihood by 2.8-fold (OR = 2.754, 95% CI 1.43-5.273) (p < 0.001), after various adjustments made. Lack of fish oil, white meat, vegetables, soy products, nuts and dairy products (especially during adolescence) in daily regimens and lack of sun exposure were significantly associated with premenopausal breast cancer risk in this region. Conclusions: This study suggested that animal fat increases the risk of premenopausal breast cancer but many other dietary and non-dietary factors including calcium and vitamin D deficiency are consistently associated with increased odds of breast cancer in this region.

• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3537-3540
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• 2014

Background: Osteosarcomas are the most common solid malignancies of bone. In the last two decades there have been no concrete developments in their systemic treatment. In this trial we aimed to present our osteosarcoma patient clinical and demographic outcomes. Materials and Methods: Patients treated and followed up for osteosarcoma in Ankara Numune Education and Research Hospital from 2002 to 2012 were reviewed retrospectively. Results: A total of 21 patients (15 male, 6 female) were diagnosed with osteosarcoma. The disease was located at extremities in 76% and in 14% was metastatic at the time of diagnosis. Median disease free survival (DFS) was 36 months in non-metastatic patients and median progression free survival (PFS) was 2 months in metastatic patients (p<0.0001). Median overall survival (OS) was 80 months and 4 months, respectively (p=0.012). There were no survival differences in terms of presentation with pathological fracture, tumor size, tumor grade, alkaline phosphatase and lactate dehydrogenase level and type of chemotherapy regimen. Conclusions: Tumor site and stages are the most important prognostic factors for osteosarcoma. Extremity primary tumors have beter survival rates than non-extremity tumors. As a result of the use of effective chemotherapy the long term survival rates have improved from 10-20% to 60-70% in the last decades but we need more active agents, especially for metastatic cases.

• 보건행정학회지
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• 제22권1호
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• pp.49-64
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• 2012

With the burden of chronic diseases mounting among the population as a result of its aging, the importance of health examination is being stressed in order to identify and manage diseases in the early stage. Health examination in Korea is divided largely into periodic health examination provided as a national health screening program and individual physical checkups. The advantages of the former include little economic burden on the examined and those of the latter include the freedom of the individual to select various examination headings depending on the individual's characteristics and preferences. With both examinations now being expanded, empirical analyses from various standpoints are needed. This study proposes to analyze traits of the examined and non-examined as shown in the facts and figures of the 1st and 2nd Korean Longitudinal Study of Ageing (KLoSA), thereby make the determinant factors clear leading to the acceptance of the examinations, and analyze the effects of the examinations upon maintaining or moving to healthy lifestyle. It was confirmed that demographic features such as gender and age, socioeconomic features such as the level of education, place of residence and household income, physical and mental state of health such as chronic disease and dementia, and daily living habits are significantly related with whether to accept physical examination. It is also confirmed that physical examination leads to non-smoking, regular physical exercises and regular dietary habits. It is suggested that, to enhance effects of health examinations, follow-up management programs making use of results of health examinations be further expanded, and the national health screening program be more actively put into operation for the bracket lying in the blind spot of the program.