• Title/Summary/Keyword: non-Human

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Novel non-apoptotic cell death: ferroptosis (새로운 non-apoptotic 세포사멸: ferroptosis)

  • Woo, Seon Min;Kwon, Taeg Kyu
    • Journal of Yeungnam Medical Science
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    • v.34 no.2
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    • pp.174-181
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    • 2017
  • Ferroptosis is a newly recognized type of cell death that results from iron-dependent lipid peroxidation and is different from other types of cell death, such as apoptosis, necrosis, and autophagic cell death. This type of cell death is characterized by mitochondrial shrinkage with an increased mitochondrial membrane density and outer mitochondrial membrane rupture. Ferroptosis can be induced by a loss of activity of system $X_c{^-}$ and the inhibition of glutathione peroxidase 4, followed by the accumulation of lipid reactive oxygen species (ROS). In addition, inactivation of the mevalonate and transsulfuration pathways is involved in the induction of ferroptosis. Moreover, nicotinamide adenine dinucleotide phosphate oxidase and p53 promote ferroptosis by increasing ROS production, while heat shock protein beta-1 and nuclear factor erythroid 2-related factor 2 inhibit ferroptosis by reducing iron uptake. This article outlines the molecular mechanisms and signaling pathways of ferroptosis regulation, and explains the roles of ferroptosis in human disease.

Study on the Identification Methods of the Non-agglutinating Vibrio (NAG Vibrio의 검사에 관한 소고)

  • Lee M. W.
    • Journal of environmental and Sanitary engineering
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    • v.2 no.2 s.2
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    • pp.61-67
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    • 1987
  • The genus Vibrio contains some of the most important intestinal pathogens of humans, including Vibrio cholerae, the cause of epidemic Asiatic cholera. A group of organisms which have been reffered to as the non-agglutinating vibrio (NAG) do not agglutinate in the Vibrio cholerae 0 group 1 antisera, but are indistinguishable from the 0-1 group both chemically and genetically. Non-O-l Vibrio cholerae can cause isolated as well as focal outbreaks of diarrhea, but the volume of fluid loss does not approach that of classic cholera, and the disease is usually self-limiting. These free-living organisms are found world-widely distributed in the environment including sewage, contaminated water, estuaries, seafood and animals. These strains involved in several cases were isolated from the environment and some patients of diarrhea, and a few epidemiologic reports indicated the wide distribution of the strains throughout the country, giving an attention to the role the organisms may play in an outbreak of diarrhea in Korea. More research on the epidemiology, serologic typing and virulence of the group of organisms, should be, therefore, done to obtain a complete understanding of their role in human disease.

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A Study on the Process of Forming Peer Relations between Students with Disabilities and Non-disabled Students

  • Cho, Woo-Hong;Joo, Young-Shin
    • Journal of the Korea Society of Computer and Information
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    • v.22 no.10
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    • pp.189-194
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    • 2017
  • The purpose of this study was to find out the necessary conditions and factors what effect as a society member through the students with disabilities to have a positive and mutual peer relationship with their classmates in the school and by them analyzed formation process and elucidate signification. The research method focused on the data summarized and enumerated through the investigation methods such as two in-depth interviews and two observation activities part, and the data which are commonly stated or observed in the data. The results of this study start that the factors of peer relationship formation between children with disabilities and their with non-disabled children are caused by lack of prejudice or lack of awareness. However, continuous cognizance improvement program, teacher's education guidance, the age have presence sense and subject about friend equating idea was mainly shown of school education or local community.

Flow Characteristics of Non-Newtonian Fluids in the Stenosed Branch Tubes (협착이 발생된 분기관내 비뉴턴유체의 유동특성 연구)

  • Suh, S.H.;Yoo, S.S.;Roh, H.W.
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.8 no.3
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    • pp.307-316
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    • 1996
  • The objective of present study is to obtain information on the stenosis effects in the branch tubes for industrial piping system and atherogenesis processing in human arteries. Numerical solutions for flows of Newtonian and non-Newtonian fluids in the branch tubes are obtained by the finite volume method. Centerline velocity and pressure along the bifurcated tubes for water, blood and aqueous Separan AP-273 solution are computed and the numerical results of blood and the Separan solution are compared with those of water. Flow phenomena in the stenosed branch tubes are discussed extensively and predicted effectively. The effects of stenosis on the pressure loss coefficients are determined.

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Rational Theories of Discrimination and the Implications for Employment Relations and Transactions (합리적 차별이론과 고용관계 및 거래 관계에 대한 영향)

  • 이세재
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.24 no.69
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    • pp.36-49
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    • 2001
  • Group level discriminations are observed in employment relations and other transactions in the form of residential occupational and production segregation and differential treatments. Recent developments in the rational theories of discrimination both on the market level and the non-market level are reviewed in terms of their relative strengths, weaknesses and complementarities. Taste discrimination could remain much suppressed in the market but could effect much chain reaction through various ways of statistical discrimination, price discrimination, human capital investment and segregation. Taste discrimination could also take the more structured form of co-workers' requiring compensation for reduced productivity due to increasing interactions with members of different language and culture in a non-segregative system. If could also be viewed in the framework of brand learning models. Non-market models of discrimination are seen to be an essential part to explain extended modes of discrimination.

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Learning Orientation Factors Affecting Company Innovation and Innovation Capability: Textile versus Non-textile Manufacturers

  • Yoh, Eun-Ah
    • International Journal of Human Ecology
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    • v.10 no.1
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    • pp.1-11
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    • 2009
  • The effect of learning orientation on company innovation and innovation capability are explored based on survey data collected from 154 small and medium-sized manufacturing firms. The theoretical links between learning orientation and company innovation as well as innovation capability are investigated in four research models that compare textile and non-textile manufacturing firms. Learning orientation has a significant effect on company innovation and innovation capability in the model test. However, some of the three segmented factors (commitment to learning, shared vision, and open-mindedness) of learning orientation had no significant effect on company innovation and innovation capability. Company innovation and innovation capability of textile manufacturing firms are predicted by the commitment to learning and shared vision, whereas those of non-textile firms were determined by shared vision and open-mindedness. Differences show that firms may need to put weight on some distinctive aspects of learning orientation according to the business categories in order to enhance company innovation.

The Turnover Motives of Clothing Salesperson

  • Jung, Hyun-Ju;Han, Young-Shim
    • Journal of Fashion Business
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    • v.10 no.6
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    • pp.131-145
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    • 2006
  • The study used 24 clothing salespersons who had turnover experiences. It used a qualitative research method, through which the following turnover motives were found. The turnover motives can be classified into two: voluntary and non-voluntary. The voluntary turnover motives include marriage, career change, wages, human relationship, family moving, study abroad, health problems, and so forth. This study finds that some salespersons made a turnover because they did not like the products and brand or they preferred another products and brand. This kind of turnover is unique in the field of clothing sales and seldom found in the motives of salesperson turnover in other fields. The non-voluntary turnover motives are caused by non-personal, circumstantial factors which include the bankruptcy of companies due to economic depression, withdrawal of salesroom from department stores due to low sales, etc. This means that the creation, rise, and fall of fashion brands are closely related to frequent turnover of clothing sale associates. As there are various motives for the salesperson turnover, so it is necessary for the clothing industry to examine and investigate the trends of its salespersons and establish an appropriate policy to cope with the matter.

Application of infrared thermography to the pulp vitality test

  • Terada, R.;Hosoya, N.;lino, F.;Komoriyama, M.;Hirano, S.;Arai, T.
    • Proceedings of the KACD Conference
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    • 2003.11a
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    • pp.581-581
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    • 2003
  • The purpose of this study was to search non-invasive and reproductive pulp test. Temperature of the crown surface was measured using the infrared thermography, and the pulp test was investigated with difference of crown temperature of the vital and the non-vital tooth in vitro and in vivo. Twenty extracted human maxillary central incisors were used in this study. Two sample teeth after access cavity preparation were arranged setting with one pair. Then, the each tooth wes estimated as the vital and the non-vital tooth.(중략)

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Effect of Depressive Vulnerability on Interpersonal Problems among University Students: Focusing on Moderating Effect of Ego-Resilience (대학생의 우울취약성이 대인관계문제에 미치는 영향: 자아탄력성의 조절효과를 중심으로)

  • Han, Hye Rim;Lee, Jimin
    • Human Ecology Research
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    • v.57 no.2
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    • pp.213-224
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    • 2019
  • This study investigates the effect of depressive vulnerability on the interpersonal problems of university students. We explore the moderating effects of ego-resilience on the relation between depressive vulnerability and interpersonal problems. We selected 380 university students as participants from Daegu and Gyeongsan cities. Collected data was analyzed by descriptive statistics, Pearson's correlation, moderating effect with SPSS 23.0. PROCESS, a SPSS macro program developed by Hayes (2013). The findings are as follows. First, there were significant correlations between non-sociability and dependency, self-criticism, non-self-assertiveness, over-consideration, dominance, personal relations, emotion control, and optimism. Second, ego-resilience was found to moderate the relationship between depressive vulnerability and non-self- assertiveness, over-consideration, and dominance among university students. This study suggests that intervention to address ego-resilience are important to resolve the interpersonal problems of university students.

A Study on a Chatbot Service Model Architecture using Open Source Chatbot Builders

  • Kim, Cheong Ghil
    • Journal of the Semiconductor & Display Technology
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    • v.21 no.4
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    • pp.14-17
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    • 2022
  • Due to the development of IT technology and the on-going Coronavirus disease, non-face-to-face services have been activated. To overcome the inconvenience of non-face-to-face service, service providers have adopted chatbots as a way to feel like a human being. As the increasing chatbot services, chatbot builders have emerged, which can help non-developers to build them. Although its popularity has increased, its performance evaluation has not been conducted on such chatbot builders. In this paper, we implement a prototype chatbot that classifies hospital departments in the medical field using Dialogflow and Rasa, which are popular chatbot builders. By measuring the accuracy of the chatbot's classification of medical subjects, we evaluated the level of accuracy that the most used chatbot builder can have when they are used to build a chatbot service. The simulation results showed that Dialogflow had 87%, 65%, and 60%, and Rasa did 64%, 70%, and 63% in surgery dermatology, and otolaryngology, respectively.