• KSII Transactions on Internet and Information Systems (TIIS)
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• 제14권3호
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• pp.1104-1120
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• 2020

The chest X-rays are a common way to diagnose lung cancer or pneumonia. In particular, the finding of a lung nodule is the most important problem in the early detection of lung cancer. Recently, a lot of automatic diagnosis algorithms have been studied to find the lung nodules missed by doctors. The algorithms are typically based on segmentation network like U-Net. However, the occurrence of false positives that similar to lung nodules present outside the lungs can severely degrade performance. In this study, we propose a multi-task learning method that simultaneously learns the lung region and nodule-labeled data based on the prior knowledge that lung nodules exist only in the lung. The proposed method significantly reduces false positives outside the lung and improves the recognition rate of lung nodules to 83.8 F1 score compared to 66.6 F1 score of single task learning with U-net model. The experimental results on the JSRT public dataset demonstrate the effectiveness of the proposed method compared with other baseline methods.

• 한국정보전자통신기술학회논문지
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• 제8권4호
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• pp.319-326
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• 2015

본 논문에서는 3차원 역학 모델을 이용한 폐 결절 분할 방법을 제안한다. 제안된 폐결절 분할 방법은 세 가지 과정으로 구성된다. 첫 번째, 초기 3차원 역학 모델을 생성한다. 생성된 모델은 삼각형 메쉬로 구성되어져 있고 구의 형태를 갖는다. 두 번째, 구성된 초기 모델의 점들을 변화시킨다. 세 번째, 각각의 변화에 따라 외부 에너지와 내부에너지를 계산 한다. 내부 에너지는 형태 기반 에너지로 구성되어 있고, 외부에너지는 음영값 기반 에너지로 구성된다. 이 초기 모델을 변화시키고, 변화에 따른 에너지의 최소값을 찾는 과정을 반복한다. 모델의 에너지가 수렴되면 이를 이용하여 결절을 분할한다. 제안된 방법은 기존 방법에 비하여 정확도가 크게 개선되었다.

• 한국멀티미디어학회논문지
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• 제23권3호
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• pp.468-475
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• 2020

In this paper, we proposed a three-dimensional visualization system for medical images in augmented reality based on deep learning. In the proposed system, the artificial neural network model performed fully automatic segmentation of the region of lung and pulmonary nodule from chest CT images. After applying the three-dimensional volume rendering method to the segmented images, it was visualized in augmented reality devices. As a result of the experiment, when nodules were present in the region of lung, it could be easily distinguished with the naked eye. Also, the location and shape of the lesions were intuitively confirmed. The evaluation was accomplished by comparing automated segmentation results of the test dataset to the manual segmented image. Through the evaluation of the segmentation model, we obtained the region of lung DSC (Dice Similarity Coefficient) of 98.77%, precision of 98.45%, recall of 99.10%. And the region of pulmonary nodule DSC of 91.88%, precision of 93.05%, recall of 90.94%. If this proposed system will be applied in medical fields such as medical practice and medical education, it is expected that it can contribute to custom organ modeling, lesion analysis, and surgical education and training of patients.

• 대한임베디드공학회논문지
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• 제17권5호
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• pp.265-272
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• 2022

As the risk of lung cancer has increased, early-stage detection and treatment of cancers have received a lot of attention. Among various medical imaging approaches, computer tomography (CT) has been widely utilized to examine the size and growth rate of lung nodules. However, the process of manual examination is a time-consuming task, and it causes physical and mental fatigue for medical professionals. Recently, many computer-aided diagnostic methods have been proposed to reduce the workload of medical professionals. In recent studies, encoder-decoder architectures have shown reliable performances in medical image segmentation, and it is adopted to predict lesion candidates. However, localizing nodules in lung CT images is a challenging problem due to the extremely small sizes and unstructured shapes of nodules. To solve these problems, we utilize atrous spatial pyramid pooling (ASPP) to minimize the loss of information for a general U-Net baseline model to extract rich representations from various receptive fields. Moreover, we propose mixed-up attention mechanism of reverse, boundary and convolutional block attention module (CBAM) to improve the accuracy of segmentation small scale of various shapes. The performance of the proposed model is compared with several previous attention mechanisms on the LIDC-IDRI dataset, and experimental results demonstrate that reverse, boundary, and CBAM (RB-CBAM) are effective in the segmentation of small nodules.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제17권3호
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• pp.678-700
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• 2023

Diagnosing breast diseases using ultrasound (US) images remains challenging because it is time-consuming and requires expert radiologist knowledge. As a result, the diagnostic performance is significantly biased. To assist radiologists in this process, computer-aided diagnosis (CAD) systems have been developed and used in practice. This type of system is used not only to assist radiologists in examining breast ultrasound images (BUS) but also to ensure the effectiveness of the diagnostic process. In this study, we propose a new approach for breast lesion localization and segmentation using a multi-scale pyramid of the ultrasound image of a breast organ and a convolutional semantic segmentation network. Unlike previous studies that used only a deep detection/segmentation neural network on a single breast ultrasound image, we propose to use multiple images generated from an input image at different scales for the localization and segmentation process. By combining the localization/segmentation results obtained from the input image at different scales, the system performance was enhanced compared with that of the previous studies. The experimental results with two public datasets confirmed the effectiveness of the proposed approach by producing superior localization/segmentation results compared with those obtained in previous studies.

• 방송공학회논문지
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• 제18권5호
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• pp.702-712
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• 2013

본 논문은 흉부 CT 영상에서 폐 흉벽에 결절 및 폐혈관이 붙어 있는 경우에도 폐 정보의 손실 없이 폐와 기관지를 분리할 수 있는 알고리즘을 제안 하였다. 마스크 영상의 활용은 폐 및 기관지 분할에서 시간 단축 및 성능을 향상 시킬 수 있었다. 또한 폐 흉벽과 밝기값이 같은 결절을 찾아 제거 하는 방법은 좌 우측폐의 외곽 영상을 2진 영상으로 변환하고, 형태학적 정보를 활용함으로써 가능 하였다. 마지막으로 제거된 부분의 외곽선 연결은 거리가 고려된 최적 화소 추가와 3차 Spline 보간법을 적용하였다. Matlab 시뮬레이션 결과 제안된 알고리즘은 기존 문제점이 보완됨을 확인 할 수 있었다.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2011년도 한국컴퓨터종합학술대회논문집 Vol.38 No.1(C)
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• pp.365-368
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• 2011

흉부 CT 영상은 각종 흉부 질환의 진단에 널리 사용되고 있으며, 영상 분석 기술을 이용하여 암이나 다양한 형태의 종양 등의 관심 영역(region-of-interest)을 자동으로 탐지하는 기법들이 최근 많이 연구되고 있다. 본 논문에서는 흉부 CT 영상에서 연속된 여러 장의 2D 영상의 변화를 분석하여 중요 관심 영역인 노듈(nodule)을 찾는 방법을 제안한다. 인접 영상에서의 노듈의 연속성과 크기의 변화, 모양, 밝기의 특징을 분석하여 노듈을 검출하였고, 실험 결과, 상당한 정도의 정확도를 보였다. 향후 추가적인 연구를 통하여 실제 환경에서도 활용 가능할 것으로 기대된다.