• Nuclear Engineering and Technology
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• v.55 no.3
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• pp.827-838
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• 2023

Centrifugal pump is a key part of nuclear power plant systems, and its health status is critical to the safety and reliability of nuclear power plants. Therefore, fault diagnosis is required for centrifugal pump. Traditional fault diagnosis methods have difficulty extracting fault features from nonlinear and non-stationary signals, resulting in low diagnostic accuracy. In this paper, a new fault diagnosis method is proposed based on the improved particle swarm optimization (IPSO) algorithm-based variational modal decomposition (VMD) and relevance vector machine (RVM). Firstly, a simulation test bench for rotor faults is built, in which vibration displacement signals of the rotor are also collected by eddy current sensors. Then, the improved particle swarm algorithm is used to optimize the VMD to achieve adaptive decomposition of vibration displacement signals. Meanwhile, a screening criterion based on the minimum Kullback-Leibler (K-L) divergence value is established to extract the primary intrinsic modal function (IMF) component. Eventually, the factors are obtained from the primary IMF component to form a fault feature vector, and fault patterns are recognized using the RVM model. The results show that the extraction of the fault information and fault diagnosis classification have been improved, and the average accuracy could reach 97.87%.

• Smart Structures and Systems
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• v.31 no.5
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• pp.501-516
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• 2023

Dynamic irregularity and acceleration of bridges subjected to high-speed trains provide crucial information for comprehensive evaluation of the health state of under-track structures. This paper proposes a novel approach for real-time estimation of vertical track dynamic irregularity and bridge acceleration using deep generative adversarial network (GAN) and vibration data from in-service train. The vehicle-body and bogie acceleration responses are correlated with the two target variables by modeling train-bridge interaction (TBI) through least squares generative adversarial network (LSGAN). To realize supervised learning required in the present task, the conventional LSGAN is modified by implementing new loss function and linear activation function. The proposed approach can offer pointwise and accurate estimates of track dynamic irregularity and bridge acceleration, allowing frequent inspection of high-speed railway (HSR) bridges in an economical way. Thanks to its applicability in scenarios of high noise level and critical resonance condition, the proposed approach has a promising prospect in engineering applications.

• Journal of Ginseng Research
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• v.47 no.6
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• pp.687-693
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• 2023

Due to the Covid-19 pandemic more than 6 million people have died, and it has bought unprecedented challenges to our lives. The recent outbreak of monkeypox virus (MPXV) has brought out new tensions among the scientific community. Currently, there is no specific treatment protocol for MPXV. Several antivirals, vaccinia immune globulin (VIG) and smallpox vaccines have been used to treat MPXV. Ginseng, one of the more famous among traditional medicines, has been used for infectious disease for thousands of years. It has shown promising antiviral effects. Ginseng could be used as a potential adaptogenic agent to help prevent infection by MPXV along with other drugs and vaccines. In this mini review, we explore the possible use of ginseng in MPXV prevention based on its antiviral activity.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.17 no.11
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• pp.3003-3029
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• 2023

The rapid evolution of the IoT has paved the way for new opportunities in smart city domains, including e-health, smart homes, and precision agriculture. However, this proliferation of services demands effective SLAs between customers and service providers, especially for critical services. Difficulties arise in maintaining the integrity of such agreements, especially in vulnerable wireless environments. This study proposes a novel SLA management model that uses an SDN-Enabled WSN consisting of wireless nodes to interact with smart contracts in a straightforward manner. The proposed model ensures the persistence of network metrics and SLA provisions through smart contracts, eliminating the need for intermediaries to audit payment and compensation procedures. The reliability and verifiability of the data prevents doubts from the contracting parties. To meet the high-performance requirements of the blockchain in the proposed model, low-cost algorithms have been developed for implementing blockchain technology in wireless sensor networks with low-energy and low-capacity nodes. Furthermore, a cryptographic signature control code is generated by wireless nodes using the in-memory private key and the dynamic random key from the smart contract at runtime to prevent tampering with data transmitted over the network. This control code enables the verification of end-to-end data signatures. The efficient generation of dynamic keys at runtime is ensured by the flexible and high-performance infrastructure of the SDN architecture.

• BMB Reports
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• v.57 no.1
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• pp.50-59
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• 2024

The application of gene engineering in livestock is necessary for various reasons, such as increasing productivity and producing disease resistance and biomedicine models. Overall, gene engineering provides benefits to the agricultural and research aspects, and humans. In particular, productivity can be increased by producing livestock with enhanced growth and improved feed conversion efficiency. In addition, the application of the disease resistance models prevents the spread of infectious diseases, which reduces the need for treatment, such as the use of antibiotics; consequently, it promotes the overall health of the herd and reduces unexpected economic losses. The application of biomedicine could be a valuable tool for understanding specific livestock diseases and improving human welfare through the development and testing of new vaccines, research on human physiology, such as human metabolism or immune response, and research and development of xenotransplantation models. Gene engineering technology has been evolving, from random, time-consuming, and laborious methods to specific, time-saving, convenient, and stable methods. This paper reviews the overall trend of genetic engineering technologies development and their application for efficient production of genetically engineered livestock, and provides examples of technologies approved by the United States (US) Food and Drug Administration (FDA) for application in humans.

• Advances in environmental research
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• v.12 no.2
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• pp.95-111
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• 2023

Pollution, climate change, and waste accumulation are only some of the new problems that have arisen because of the exponential population growth of the past few decades. As the global population expands, managing municipal solid trash becomes increasingly difficult. This is by far the most difficult obstacle for governments to overcome, especially in less developed nations. The improper open dumping of trash, which is causing mayhem across the country, has two immediate effects: it contaminates groundwater and surface water. Air pollution and the accumulation of greenhouse gases are both exacerbated by the release of methane and other harmful waste gases. Leachate from the landfill leaks underground and pollutes groundwater. In most cases, leachate moves into the groundwater zone and pollutes it after forming in association with precipitation that infiltrates via waste. This has far-reaching effects on people's health and disturbs the natural environment. This review article critically examines the current state of Solid Waste Management (SWM), addressing both the highlighted concerns and the government management solutions that have been put in place to address these issues. In addition, the constraints, and difficulties that India will face in the future in terms of solid waste management and the role of models for such a system are discussed.

• Journal of Distribution Science
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• v.22 no.4
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• pp.69-77
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• 2024

Purpose: This paper aims to tackle the challenges and opportunities of cities' response to COVID-19 and provide cities with policy implications for better adapting to the post-pandemic era. Cities around the world are facing new challenges and have had to adapt to maintain social distancing measures while also addressing equity and social inclusion issues. Research design, data and methodology: The research methodology relies on an examination of existing literature, coupled with trend analysis employing discourse analysis to investigate post-pandemic urban resilience. The article also attempts to employ the concepts of adaptive urbanism and spatial flexibility and their potential to address these challenges not only in response to the pandemic, but also in the long-term. Results: The article explores the impact of COVID-19 on urban spatial structure through a public health lens and proposes actions that cities are able to take to enhance their resilience in the aftermath of the pandemic. Conclusions: It underscores the significance of reconstructing with improved distribution dynamics and provides valuable guidance for companies and policymakers on navigating these challenges. Ultimately, it also suggests that the pandemic has initiated a worldwide restructuring of urban planning, potentially leading to the emergence of smart cities grounded in science and technology.

• Journal of Korean Academy of Nursing
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• v.18 no.2
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• pp.162-188
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• 1988

The purpose of this study is to guide the direction of the Korean nursing education to analysize ⑴ the philosophy and objectives ⑵ curriculum, and ⑶ educational environment. This analysis is based on the data from 50 nursing schools (14 4-year colleges and 35 3-year colleges) The survey was conducted from Dec. 1986 through Jan. 1987 by mail. 1) Educational philosophy and objectives 10 4-year colleges and 8 3-year college program have curricular philosoph. Most popular curricular philosophies are human beings, health, nursing, nursology, nursing education, nurses role in the present and in the future. 10 nursing schools mentioned that human being is the subject to interact with : environment physically, mentally and socially. 2 schools mentioned that health is the state of functioning well physically, mentally and socially. 13 schools mentioned that the nursing is the dynamic act to maintain and to promote the highest possible level of health. 4 schools mentioned that the nursology is an applied science. 4 schools mentioned that nursing education is the process to induce the behavioural changes based on the individual ability. There is different opinion about the nurses' role between 4-year college and 3-year college. In the responses from 4-year colleges they focus on the leadership in effective changes, self-regulating and self-determining responsibilities, applying the new technology, continuing education, and participation in research to further nursing knowledge. In the responses from 3-year colleges, they focus on the education in college, primary health care nursing, direct care provider and public health education. Among 50 respondents 40 schools have educational goals which can be divided into two categories. One is to establish the moral and the other is to develop the professionalism. 2) Curriculm The analsis of curriculum is only based on the data from the 4-year colleges because the most of 3-year colleges follow the curriculum guideline set by the Ministry of Education. a) Comparison of the credits in cultural subject and in nursing major. The average required credit for graduation is 154.6 and the median credit is the range of 140-149. The average credit of cultural subjects is 43.4. In detail, the average number of credit of required course and elective courses are 24.1 and 19.3 respectively. The average credit for major subject is 111.2. In detail, the average credit for required courses and electives course are 100.9 and 10.4 respectively. In 5 colleges, students are offered even on elective course b) Comparison of the credit by class. The average earned credits are as follows : 41.1 in freshman, 400 in sophormore 38.3 in junior and 32.4 in senior. Cultural subjects are studied in early phases. c) Comparison of the compulsory and elective cultural subject by institute. The range of credit is 7-43 in compulsory cultural subjects and there are lot of differences among institutions. While all respondents require liberal arts as compulsary subjects, few respondents lists social science, natural science and behavioral science as required subjects. Social science-related subjects are frequently chosen as cultural subjects d) Distribution of creditsin cultural subjects by institute. The liberal art subjects are taught in 20 institute. English and physical education courses are taught in all instituions. The social science subjects are taught in 15 colleges and the basic Psycology and the Basic sociology are the most popular subjects. The natural science subjects are taught in 7 colleges and Biology and Chemistry are the most popular subjects among them. e) Distribution of credits in major basic courses by institute. Most of the institutes select Anatomy, Microbiology, Physiology, biochemistry and Pathology as basic major courses. f) Comparison of the required and elective courses for nursing major by institutions. Subjects and credit ranges in major are varing by institute. More than half of the respondents select the following subjects as required major subjects. (1) Adults Health Nursing and Practice (19.5 credits) (2) Mother and Child Care and Practice (8.9 credits) (3) Community Health Care and Practice (8.5 credits) (4) Psychiatric Nursing Care and Practice (8.1 credits) (5) Nursing Management and Practice (3.9 credits) (6) Fundamental of Nursing, Nursing Research and Health Assessment and Practice. Three institutions select Introduction to nursing, Rehabilitation Nursing, School Nursing, Public Health Nursing, Nursing English, Communication, Human Development as electives in nursing major. 3) Educational environment a) Nursing institution There are forty-three 3-year colleges and seventeen 4-year colleges and 81.4% of which are private b) Number of students and faculty 19.2% of the students are in 4-year colleges and 80.8% of the students are in 3-year colleges. In 4-year colleges, the number of nursing faculty members is in the other of assistant professor, instructor and professor. In 3-year colleges, the orderiis lecturer, associate professor, full time instructor and assistant professor. In 4-year colleges, 18.8 students are allocated per nursing faculty and in 3-year colleges, 33.1 students are allocated per nursing faculty. c) Clinical practices 66.7% of the 4-year colleges practice over 1201 hours in clinic and 28.5% of 3-year colleges practice over 1201 hours in clinic. In 4-year colleges, 11.5 students are allocated per nursing faculty and in 3-year colleges,17 students are allocated per nursing faculty The survey shows no difference in the procedure between 4-year colleges and 3-year colleges but 3-year colleges choose the more variety practicing site such as special hospital and community health clinic. d) Audiovisual facilities The survey shows a lot of difference in audiovisual facilities among institution and 3-year colleges are less equipped than 4-year colleges.

• Natural Product Sciences
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• v.8 no.1
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• pp.1-15
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• 2002

An International Cooperative Biodiversity Group (ICBG) program based at the University of Illinois at Chicago initiated its activities in 1998, with the following specific objectives: (a) inventory and conservation of of plants of Cuc Phuong National Park in Vietnam and of medicinal plants of Laos; (b) drug discovery (and development) based on plants of Vietnam and Laos; and (c) economic development of communities participating in the ICBG project both in Vietnam and Laos. Member-institutions and an industrial partner of this ICBG are bound by a Memorandum of Agreement that recognizes property and intellectual property rights, prior informed consent for access to genetic resources and to indigenous knowledge, the sharing of benefits that may arise from the drug discovery effort, and the provision of short-term and long-term benefits to host country institutions and communities. The drug discovery effort is targeted to the search for agents for therapies against malaria (antimalarial assay of plant extracts, using Plasmodium falciparum clones), AIDS (anti-HIV-l activity using HOG.R5 reporter cell line (through transactivation of the green fluorescent protein/GFP gene), cancer (screening of plant extracts in 6 human tumor cell lines - KB, Col-2, LU-l, LNCaP, HUVEC, hTert-RPEl), tuberculosis (screening of extracts in the microplate Alamar Blue assay against Mycobacterium tuberculosis $H_{37}Ra\;and\;H_{37}Rv),$ all performed at UIC, and CNS-related diseases (with special focus on Alzheimer's disease, pain and rheumatoid arthritis, and asthma), peformed at Glaxo Smith Kline (UK). Source plants were selected based on two approaches: biodiversity-based (plants of Cuc Phuong National Park) and ethnobotany-based (medicinal plants of Cuc Phuong National Park in Vietnam and medicinal plants of Laos). At mc, as of July, 2001, active leads had been identified in the anti-HIV, anticancer, antimalarial, and anti- TB assay, after the screening of more than 800 extracts. At least 25 biologically active compounds have been isolated, 13 of which are new with anti-HIV activity, and 3 also new with antimalarial activity. At GSK of 21 plant samples with a history of use to treat CNS-related diseases tested to date, a number showed activity against one or more of the CNS assay targets used, but no new compounds have been isolated. The results of the drug discovery effort to date indicate that tropical plant diversity of Vietnam and Laos unquestionably harbors biologically active chemical entities, which, through further research, may eventually yield candidates for drug development. Although the substantial monetary benefit of the drug discovery process (royalties) is a long way off, the UIC ICBG program provides direct and real-term benefits to host country institutions and communities.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.4
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• pp.543-550
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• 2018

The rapid growth of IoT technology induced by the fourth industrial revolution has resulted in research into various types of wireless sensors, and applications based on this technology are prevalent in many areas. However, among the various sites where this technology is used, railway bridges and tunnels with lengths of tens of kilometers have problems with data acquisition, due to the signal noise induced by the long distance measurement and EMI induced by the high voltage power feeding system, when conventional electric sensors are used. To overcome these problems, many studies on fiber optic sensors have been conducted as a substitute for the conventional electric sensors. However, restrictions on the types of fiber optic sensors have limited their application in railways. For this reason, a hybrid measurement system with IoT based wireless data communication, in which both electric and fiber optic sensors can be applied simultaneously, has been developed. In this study, in order to evaluate the applicability of the hybrid measurement system developed in the previous study, a real-time test for 4 types of measurement environments, which reflect possible railway sites, is performed. As a result, it was confirmed that the signals from both the electric and fiber optic sensors, which were acquired at a remote area in real-time, showed good agreement with each other and that this measurement system has the potential to handle sensors with a sampling rate of 2.5 kHz. In the future, it is expected that the IoT-based hybrid measurement system will contribute to the improvement of structural safety by enabling real-time structural health monitoring when applied to various measurement sites.