• Molecular & Cellular Toxicology
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• v.4 no.1
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• pp.85-91
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• 2008

These days there is a constant possibility of exposure to UV radiation which can cause abnormal production of melanin and result in skin disease such as hyperpigmentation and melanoma. Many materials were investigated for skin whitening and protection against UV radiation. In this study, we assessed the melanogenesis inhibitory activities of Korean Red Ginseng (KRG, Ginseng Radix Rubra) and Ginkgo (EGb 761 Ginkgo Biloba) in an attempt to develop a new skin whitening agent derived from natural products. B16F10 melanoma cells were treated for 48 hr with KRG and EGb 761. The inhibitory effect on melanogenesis was measured and related cytokines and proteins expression were also investigated by RT-PCR and Western blotting. In addition, we also assessed the effects of these substances on the skin of C57BL/6 mice. Cell growth, melanin content and tyrosinase activity were inhibited effectively in B16F10 melanoma cells treated with KRG and EGb 761. Moreover, tyrosinase mRNA expression was inhibited clearly and melanogenesis related proteins (MRPs) containing tyrosinase, TRP1 and TRP2 were also reduced by KRG and EGb761, while cytokines such as IL-$1{\beta}$ and IL-6 were induced. In the case of UV irradiated mice, we observed induction of cytokine mRNA levels and reduction of MRPs mRNA expression. In addition, a decrease in pigmentation from treatment with KRG and EGb 761 on the skin of mice was observed. These results indicate that KRG and EGb 761 inhibit melanogenesis in B16F10 cells and have display protective activities against UVB. Therefore, we suggest that KRG and EGb 761 are good candidates to be used as whitening agents and UVB protectors for the skin.

• Journal of radiological science and technology
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• v.41 no.3
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• pp.241-247
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• 2018

The purpose of this study was to compare the ultrasound gel container washing methods for the sterilization of contaminants and to find the useful methods for the prevention of infection caused by the ultrasonic gel containers. In this experiment, a 250 mL ultrasonic gel container was used, and the ultrasonic gel used was a non-sterile gel (ECO GEL 99, SeungWon Medical, Korea). In order to evaluate the degree of contamination, new 250 mL 15 containers were divided into 5 groups to perform five types of washing by no treatment, washing with water, washing with soap, washing with bottle cleaner and high disinfection level washing. After the washing process, filled the gel container with gel and after 2 weeks, the number of colonies in the gel container was sampled repeatedly twice in the same ultrasonic laboratory and compared before and after washing. As a result of among the five cleaning methods used in this study, 87.2% and 88.9% of the soapy water washing (p = 0.028) and high level washing (p = 0.027) showed significant bacterial reduction rates, respectively. Our findings conclusively an ultrasonic gel container cleaning method for removing contaminants has been found to be an effective sterilization method at a low cost with a soapy water cleaning method. Therefore, it is expected that it will be helpful to prevent the infection caused by the ultrasonic gel container by suggesting the sterilization cleaning method that is practically useful in this study.

• Smart Structures and Systems
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• v.10 no.4_5
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• pp.411-426
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• 2012

The Canton Tower (formerly named Guangzhou New TV Tower) of 610 m high has been instrumented with a long-term structural health monitoring (SHM) system consisting of over 700 sensors of sixteen types. Under the auspices of the Asian-Pacific Network of Centers for Research in Smart Structures Technology (ANCRiSST), an SHM benchmark problem for high-rise structures has been developed by taking the instrumented Canton Tower as a host structure. This benchmark problem aims to provide an international platform for direct comparison of various SHM-related methodologies and algorithms with the use of real-world monitoring data from a large-scale structure, and to narrow the gap that currently exists between the research and the practice of SHM. This paper first briefs the SHM system deployed on the Canton Tower, and the development of an elaborate three-dimensional (3D) full-scale finite element model (FEM) and the validation of the model using the measured modal data of the structure. In succession comes the formulation of an equivalent reduced-order FEM which is developed specifically for the benchmark study. The reduced-order FEM, which comprises 37 beam elements and a total of 185 degrees-of-freedom (DOFs), has been elaborately tuned to coincide well with the full-scale FEM in terms of both modal frequencies and mode shapes. The field measurement data (including those obtained from 20 accelerometers, one anemometer and one temperature sensor) from the Canton Tower, which are available for the benchmark study, are subsequently presented together with a description of the sensor deployment locations and the sensor specifications.

• Journal of Korean Academy of Nursing Administration
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• v.21 no.3
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• pp.243-253
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• 2015

Purpose: The purpose of this study was to identify the impact of practical communication strategies (PCS) on the reduction of AEs (Adverse Events) in pediatric cardiac ICU (PCICU). Methods: Intra-operative findings and care plans were documented and shared between staff members on a daily basis from the day of operation to the day of general ward transfer. Incidence of AEs was investigated in all patients who were admitted to the PCICU and was compared with incidence of AEs one year after establishment of PCS. Results: The study population consisted of 216 patients in pre-PCS group and 156 patients in post-PCS group. Incidence of readmission decreased from 6.0% (13/216) in pre-PCS group to 0.6% (1/156) in post-PCS group (${\chi}^2=7.23$, p=.010). Incidence of other major complications decreased from 4.2% (9/216) to 0.6% (${\chi}^2=6.66$, p=.012). Minor AEs such as intervention omission, order error, and protocol misunderstanding were reduced from 23.3 cases per 100 patient-days to 7.5 cases per 100 patient-days (${\chi}^2=20.31$, p<.001). Conclusion: Handover protocol is an effective strategy to reduce AEs for critically ill patients after pediatric cardiac surgery. Efforts to develop effective communication strategies should be continued and outcome research about communication strategies for patient safety should be further studied.

• Journal of Environmental Health Sciences
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• v.46 no.2
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• pp.204-213
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• 2020

Objective: This study is aimed at investigating indoor air quality on public transportation (subway, train, and bus) according to changes in season and time. Methods: We evaluated TVOC and HCHO on public transportation based on the un-controlled parameters of the Ministry of Environment. We also measured temperature and humidity since they affect the concentration of TVOC and HCHO. For public transportation classification, subway lines were classified into Lines 1 to 4. Additionally, trains were classified as ITX and KTX. Results: When comparing summer and winter on public transportation, the concentrations of TVOC and HCHO did not show any particular tendency. However, the concentrations of TVOC and HCHO during traffic congestion was higher than levels during times of non-congestion on most public transportation. In summer and winter, the measurement results for temperature and humidity showed a normal range, so temperature and humidity did not affect the concentrations of TVOC and HCHO. In the case of TVOC, TVOC concentrations on new trains were found to be relatively higher than on older ones, but there was no statistically correlation. Conclusions: A survey was conducted on the indoor air quality on public transportation. This study also analyzed data based on TVOC and HCHO for designing policies and managing indoor air quality.

• Smart Structures and Systems
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• v.18 no.5
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• pp.955-982
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• 2016

Recent studies integrating vibration control and structural health monitoring (SHM) use control devices and control algorithms to enable system identification and damage detection. In this study real-time SHM is used to enhance structural vibration control and reduce damage. A newly proposed control algorithm, including integrated real-time SHM and semi-active control strategy, is presented to mitigate both damage and seismic response of the main structure under strong seismic ground motion. The semi-active independently variable stiffness (SAIVS) device is used as semi-active control device in this investigation. The proper stiffness of SAIVS device is obtained using a new developed semi-active control algorithm based on real-time damage tracking of structure by damage detection algorithm based on identified system Markov parameters (DDA/ISMP) method. A three bay five story steel braced frame structure, which is equipped with one SAIVS device at each story, is employed to illustrate the efficiency of the proposed algorithm. The obtained results show that the proposed control algorithm could significantly decrease damage in most parts of the structure. Also, the dynamic response of the structure is effectively reduced by using the proposed control algorithm during four strong earthquakes. In comparison to passive on and off cases, the results demonstrate that the performance of the proposed control algorithm in decreasing both damage and dynamic responses of structure is significantly enhanced than the passive cases. Furthermore, from the energy consumption point of view the maximum and the cumulative control force in the proposed control algorithm is less than the passive-on case, considerably.

• Journal of Convergence for Information Technology
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• v.10 no.4
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• pp.175-183
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• 2020

The change in the demand and perception of wigs worn for hair loss is getting better, but hair extension is emerging as a new treatment method that improves as there are inconvenient areas such as hair loss, bleaching, and tangling of wigs themselves, and time spent on unnatural hair styling and wearing wigs. The purpose of this study is to verify that the quality of life of middle-aged female hair loss is positively affected by hair growth techniques that weave wool strands into their hair. Those surveyed were middle-aged women with hair loss and were analyzed by measuring the quality of life before and after hair growth. The analysis showed that hair increased techniques affects the economic satisfaction, physical satisfaction, mental satisfaction and social satisfaction of middle-aged women with hair loss, indicating that hair increased techniques is effective in improving the quality of life for middle-aged women with hair loss. It is also expected that the beauty industry will develop high value through hair increased techniques, a blue ocean in the beauty market.

• Journal of Electrical Engineering and Technology
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• v.7 no.3
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• pp.376-383
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• 2012

A number of scientific researches are currently being conducted on the potential health hazards of power frequency electric and magnetic field (EMF). There exists a non-objective and psychological belief that they are harmful, although no scientific and objective proof of such exists. This possible health risk from ELF magnetic field (MF) exposure, especially for children under 17 years of age, is currently one of Korea's most highly contested social issues. Therefore, to assess the magnetic field exposure levels of those children in their general living environments, the personal MF exposure levels of 436 subjects were measured for about 6 years using government funding. Using the measured database, estimation formulas were developed to predict personal MF exposure levels. These formulas can serve as valuable tools in estimating 24-hour personal MF exposure levels without directly measuring the exposure. Three types of estimation formulas were developed by applying evolutionary computation methods such as genetic algorithm (GA) and genetic programming (GP). After tuning the database, the final three formulas with the smallest estimation error were selected, where the target estimation error was approximately 0.03 ${\mu}T$. The seven parameters of each of these three formulas are gender (G), age (A), house type (H), house size (HS), distance between the subject's residence and a power line (RD), power line voltage class (KV), and the usage conditions of electric appliances (RULE).

• KSCE Journal of Civil and Environmental Engineering Research
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• v.37 no.1
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• pp.195-201
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• 2017

Urbanization and industrialization have led to a severe deterioration in urban air qualities. As an air pollution is closely associated with human health, citizen has a growing concern about the air quality policy to improve their residential environment. Due to the recently advance in web- and mobile computing technologies, citizens can easily access various air quality information and public authorities utilize the social media service to communicate citizens with air quality issues. Also citizens' participation and role has been increased to improve urban air qualities. Thus, to meet the technical and societal changes, a GIS-based air quality information system is developed based upon the Ubiquitous Public Access (UPA) model in ISO19154. The proposed system employs the context information model to provide air quality information depending on citizens' health conditions and locations. Also, citizens can present their perceptions of an air quality at their current location Public authorities can thus utilize the citizens' perceptions when establishing new air quality policies.

• Korean Institute of Interior Design Journal
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• v.17 no.3
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• pp.23-33
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• 2008

After the concept of apartments was introduced in 1960s in Korea, on account of the development of architectural technology and science, high-rise residences in Korea are getting higher, and these residences have been becoming high-rise commercial/residential buildings since 1990. Nowadays, as the construction of high-rise commercial residential building complex is booming, the difference between these complex and high-rise apartments is getting smaller, and these two kind of high-rise residences are becoming new residential style in Korea. And these high-rise residences are considered the symbol of wealth owing to the marketing strategy emphasizing high quality, refined interior, a fair view, and the protection of privacy. However, high-rise residences bring about many problems related to health and psychology caused by the consumption of a large amount of energy, pollutant emission, the deterioration of the quality of indoor air, and vibration. For this reason, in this study, we tried to emphasize the necessity of environment-friendly access to provide healthy living environment and to reduce the negative effect of housing life in high-rise residences, and find the method to improve environment-friendly quality and health of residents in interior space. Therefore, this study aims to detect the problems and the items to be improved of interior spaces of high-rise residences by quantitative, qualitative analysis of the evaluation elements and the floor planning elements deduced from environment-friendly architectural certification in Korea and the other countries, and suggest the guideline to improve the environment-friendly quality of these interior spaces.