• KIEE International Transaction on Systems and Control
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• v.2D no.2
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• pp.53-58
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• 2002

In this paper, various aspects in magnetoencephalography (MEG) source localization are studied. To minimize the errors in experimental data, an approximation technique using a polynomial function is proposed. The simulation shows that the proposed technique yields more accurate results. To improve the convergence characteristics in the optimization algorithm, a hybrid algorithm of evolution strategy and sensitivity analysis is applied to the neuromagnetic inverse problem. The effectiveness of the hybrid algorithm is verified by comparison with conventional algorithms. In addition, an artificial neural network (ANN) is applied to find an initial source location quickly and accurately. The simulation indicates that the proposed technique yields more accurate results effectively.

• Progress in Superconductivity
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• v.5 no.2
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• pp.98-104
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• 2004

We analyzed a noise-sensitivity profile of a specific SQUID sensor system for the localization of brain activity. The location of a neuromagnetic current source is estimated from the recording of spatially distributed SQUID sensors. According to the specific arrangement of the sensors, each site in the source space has different sensitivity, that is, the difference in the lead field vectors. Conversely, channel noises on each sensor will give a different amount of the estimation error to each of the source sites. e.g., a distant source site from the sensor system has a small lead-field vector in magnitude and low sensitivity. However, when we solve the inverse problem from the recorded sensor data, we use the inverse of the lead-field vector that is rather large, which results in an overestimated noise power on the site. Especially, the spatial sensitivity profile of a gradiometer system measuring tangential fields is much more complex than a radial magnetometer system. This is one of the causes to make the solutions of inverse problems unstable on intervening of the sensor noise. In this study, in order to improve the localization accuracy, we calculated the noise-sensitivity profile of our 40-channel planar SQUID gradiometer system, and applied it as a normalization weight factor to the source localization using synthetic aperture magnetometry.

• 한국초전도학회:학술대회논문집
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• v.13
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• pp.59-59
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• 2003