• 제어로봇시스템학회:학술대회논문집
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• 2004.08a
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• pp.190-195
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• 2004

We propose a pattern classification algorithm using self-nonself discrimination principle of immune cells and apply it to DNA pattern classification problem. Pattern classification problem in bioinformatics is very important and frequent one. In this paper, we propose a classification algorithm based on the negative selection of the immune system to classify DNA patterns. The negative selection is the process to determine an antigenic receptor that recognize antigens, nonself cells. The immune cells use this antigen receptor to judge whether a self or not. If one composes ${\eta}$ groups of antigenic receptor for ${\eta}$ different patterns, these receptor groups can classify into ${\eta}$ patterns. We propose a pattern classification algorithm based on the negative selection in nucleotide base level and amino acid level. Also to show the validity of our algorithm, experimental results of RNA group classification are presented.

• Journal of muscle and joint health
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• v.9 no.2
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• pp.187-202
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• 2002

This study was aim to provide rheumatoid arthritis patients the basic data of development of nursing intervention to help psychosocial adaptation of rheumatoid arthritis patients as exploring the relationship among causal perception, coping pattern, psychosocial adaptation of rheumatoid arthritis. As the results of this study the mean score of causal perception of the subjects was 3.37. The score of the internal-unstable was the highest. which was followed by extra-stable, internal factor, internal-stable, external factor and external-unstable in order among the factor of causal perception. The mean score of coping pattern was 2.64. The type of coping patterns the score of the receptive coping was the highest, which was followed by wishful coping active coping and negative coping in order among the type of coping pattern. The mean score of psychosocial adaptation was 3.28. The subconcept of psychosocial adaptation the score for personal relationship was the highest, which was followed by role function and mental state in order among the psychosocial adaptation. The analysis of the relation among causal perception, coping pattern and psychosocial adaptation showed significant negative correlation between causal perception and psychosocial adaptation(r=-0.3219, P=0.002). The analysis of the relation between the type of coping pattern and psychosocial adaptation showed significant negative correlation between psychosocial adaptation and active coping(r=-0.3210, P=0.002), negative coping(r=-0.2296, P=0.032). Only causal perception(-.36) and period of illness(-.26) effected on the psychosocial adaptation were shown to the negative direction significantly. The psychosocial adaptation was explained the 17% by these two variables. Based on this study results the factor of causal perception and the type of coping pattern of rheumatoid arthritis were shown significant relations between psychosocial adaptation. We suggests that nurses in practice apply to assessing the factor of causal perception of individuals illness and the type of coping patterns when nursing interventions in rheumatoid arthritis patients.

• The Research Journal of the Costume Culture
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• v.13 no.3 s.56
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• pp.391-405
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• 2005

This study puts emphasis on showing the change of Stripe Pattern, which has been popular for a long period of time in many societies, with change in time, assessing its value as an art. During medieval period, Strife Pattern had a strong negative meaning as a sign of disgrace or inferiority, or had been used as discrimination against a mental or a sinner, who had been rejected or banished from the society. Through French Revolution, Stripe Pattern has become a symbol of liberty and equality, furthermore, the notion of society as well as countries. This event had positively affected on reevaluating its image, from inferior, negative to significant, artistic. Eventually the variety of aesthetic values of Stripe Pattern led its way to the variation of its functional value expanding its use other than fashion industry. It is anticipated that our fashion industry will flourish in creating new, creative design by understanding design and appreciating their aesthetic values with their applications to human sensibility.

• Journal of muscle and joint health
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• v.1 no.1
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• pp.71-87
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• 1994

The purpose of this study was to assess pain, discomfort, depression and coping patterns and the relations between these in chronic arthritis patients. The sampling method was a purposive sampling technique. 1) Who have been diagnosed as having chronic arthritis and. 2) Who were at the out patients clinic of rheumatoid arthritis departments of one University hospital in seoul between september, 11, 1993 to september, 18, 1993. The instruments used for this study were Graphic Rating Scales of pain, discomfort level of the activities of daily living(ADL) developed by Lee, Eun Ok and The Beck Depression inventory. The research used to measure coping patterns was a tool developed by the present study researcher. Analysis of data was done frequency, Pearson correlation coefficients, ANOVA, regression and ANCOVA. The results were summerlized as follows ; 1. Female exceed male patients in number and onset of joint pain were more prevalent in the age groups of the 40s and the 50s. The average duration of suffering from the pain were seven years six mounths. 2. The mean pain score : The mean sensory score was 119mm and the affective score was 109mm. 3. The discomfort level of ADL, the mean score was 2.95 out of a possible score of 5.0 and depression syndrome subjects were 62.2%. 4. The coping responses for each pattern were as follows : 1) "Active coping" mean score was 2.28. 2) "Wishful coping" mean score was 2.89. 3) "Receptive coping" mean score was 3.31. 4) "Negative coping" mean score was 1.82. 5. Significant differences were found in age, religion, marriage status and the coping patterns of patients. 1) In the coping pattern of "receptive coping", the score of the age groups of the 50s were higher than that of 20s, and in the coping pattern of "negative coping", the score of the age groups of the 20s were higher than other age groups. 2) In the coping pattern of "wishful coping", the score of the christian were higher than other religion groups. 3) In the coping pattern of "negative coping", the score of the marrieds were lower than other groups. 6. Patients who scored low on factor 2, wishful coping, were much more likely to report having pain sensory than patioets scoring high on this factor. 7. Patients who scored high on factor 4, negative coping, were significantly more likely to report having pain sensory than patients scoring high on this factor. Consider overall, chronic arthritis patients report using a wide varity of strategies, certain strategies such as receptive, wishful and active coping are used frequently, whereas other strategies such as negative coping are rarely used. One of the most important finding of present study is that the reported use of coping strategies is related to adjustment to a chronic pain problem. The present study suggests that negative coping is related to poor emotional adjustment as assessed by depression, but not pain ratings. Considered overall, this pattern of findings suggests that counseling patients to decreased their use of negative coping may be useful. The present study has a number of limitations. First, the sample is restricted to chronic arthritis patients. Weather chronic pain patients suffering from other types of pain syndromes use similar coping strategies needs to be determined in subsequent research. Second, the tool of coping pattern must be studied further to obtain reliability.

• Journal of Plant Biology
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• v.15 no.1
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• pp.33-41
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• 1972

Nine shrub layer communities under two relatively well conserved natural summer green forests in the central region of Korean Peninsula were studied for the pattern of stem distribution in terms of Greig-Smith's multiple split-plot experiment and for the association between the population of the two main species in terms of Kershaw's covariance analysis respectively. Four contiguous belt transects, $4{\times}64m size with 1{\times}1m$ basic unit, were set in each shrub layer communities. Significant primary clumps with $1{\times}1m or 1{\times}2m$ dimension wer observed consistently throughout the nine study sites. The primary clumps themselves were significantly distributed either regularly or at random. The association between the two principal species of each shrub layer is highly significantly either positive or negative in $1{\times}1m or 1{\times}2m$ dimension. As the plot size increases from $1{\times}1m to 8{\times}8m$ the associational trends were changed from negative to positive direction in one forests. But the change from positive to negative direction and the consistent negative association were also observed from the other forest. All of the association trends were observed only from $1{\times}1m to 4{\times}4m$ dimension. These results are suggestive that the distributional pattern of the shrub layer species under the summer green forest is simple mosaic fashioned with $1{\times}1m or 1{\times}2m$ dimension. The rest of the principal species are located in that matrix. The simple mosaic pattern of two principal species are located in that matrix. The simple mosaic pattern of two principal species seems to be controlled by change in micro-environmental pattern. Differences between the primary random group and clumped group among sites also suggest that competition exists for light or/and soil between primary clumped groups.

• International Journal of Fuzzy Logic and Intelligent Systems
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• v.4 no.2
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• pp.231-235
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• 2004

According to revealing the DNA sequence of human and living things, it increases that a demand on a new computational processing method which utilizes DNA sequence information. In this paper we propose a classification algorithm based on negative selection of the immune system to classify DNA patterns. Negative selection is the process to determine an antigenic receptor that recognize antigens, nonself cells. The immune cells use this antigen receptor to judge whether a self or not. If one composes n group of antigenic receptor for n different patterns, they can classify into n patterns. In this paper we propose a pattern classification algorithm based on negative selection in nucleotide base level and amino acid level.

• Design & Manufacturing
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• v.2 no.4
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• pp.1-4
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• 2008

Micro pattern is applied to the light guiding plate(LGP) to enhance the uniformity of the brightness of the LCD. The micro cones are molded in intaglio on the surface of the LGP. The surface roughness of each cone was 40nm and 38nm in negative and positive die for laser ablation. In chemical etching, the surface roughness was 25nm, 24nm in negative and positive. And the surface roughness of negative and positive dies were 4nm and 5nm for LIGA-reflow process.

• Korean Journal of Veterinary Service
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• v.41 no.1
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• pp.57-61
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• 2018

Canine peripheral nerve sheath tumors (PNSTs) are spindle cell tumors that arise from Schwann cells, perineural cells, fibroblasts or all of them. Based on the morphology and biologic behavior, PNSTs are divided into benign PNST (BPNST) and malignant PNST (MPNST) forms. The aim of this study is to diagnose the two cases of neoplastic tissue samples with features of PNSTs by the histopathology and immunohistochemistry. The study was performed using two specimens from small animal clinic. The first case, A was a mass, 3~4 cm in diameter, extruded from vaginal mucosa of 10-year-old spayed female mixed-breed dog. And the second case, B was a subcutaneous mass, 1.5 cm in diameter, which is originated from right hind leg of 9-year-old castrated male mixed-breed dog. Two cases were stained with hematoxylin and eosin (H&E) for histopathological examination. And also immunohistochemistry (IHC) was performed by the avidin-biotin peroxidase complex (ABC) method with antibodies specific for the following proteins: S-100 protein, smooth muscle actin (SMA) and epidermal growth factor receptor (EGFR). In results, Antoni B schwannoma pattern characterized by pleomorphic, round and fusiform polygonal cells was seen in A. In B, Antoni A pattern, densely packed spindle cells arranged in interlacing bundles was seen in addition to Antoni B pattern. In IHC, cytoplasms of neoplastic cells were diffusely labeled for S-100 expression in A and B. For SMA, both A and B show negative expression. And for EGFR, A shows negative expression but B shows partially positive expression in areas of Antoni B schwannoma pattern. The histopathologic features of two cases coupled with the S-100 immunoreactivity led to a diagnosis of PNST. For SMA, both A and B show negative expression. The diagnosis of A will be a BPNST with the negative result and B will be a MPNST with the positive result for EGFR.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2006.11a
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• pp.173-179
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• 2006

In order to explain a U-shape pattern of stock returns, Fama and French(1988) suggested the state-space model consisting of I(1) permanent component and AR(1) stationary component. They concluded the autoregression coefficient induced from the state-space model follow the U-shape pattern and the U-shape pattern of stock returns was due to both negative autocorrelation in returns beyond a year and substantial mean-reversion in stock market prices. However, we found negative autocorrelation is induced under the assumption that permanent and stationary noise component are independent in the state-space model. In this paper, we derive the autoregression coefficient based on ARIMA process equivalent to the state-space model without the assumption of independency. Based on the estimated parameters, we investigate the pattern of the time-varying autoregression coefficient and conclude the autoregression coefficient from the state-space model of ARIMA(1,1,1) process does not follow a U-shape pattern, but has always positive sign. We applied this result on the data of 1 month retums for all NYSE stocks for the 1926-85 period from the Center for Research in Security Prices.

• Journal of Oral Medicine and Pain
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• v.41 no.1
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• pp.16-20
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• 2016

Purpose: Oral lichen planus (OLP) is relatively common mucosal disease in clinical dentistry. OLP is intractable and regarded having malignant potential. Until now, there is some debate on how far OLP can be malignant, and which characteristics can be a risk factor for malignant transformation. Clinician need to know some differences between OLP and lesions similar to OLP to manage properly and suppose prognosis correctly. Therefore, the aim of this study was to divide clinical OLP into two groups and to compare the results of direct immunofluorescence (DIF) between two groups. Methods: This study was conducted on outpatients who visited at the department of Oral Medicine in Chonbuk National University Hospital from January 2007 to November 2015. Patients with DIF result were retrospectively reviewed. The selected patients were classified 'clinical typical of OLP' (CTO) or 'clinical compatible with OLP' (CCW) by modified World Health Organization diagnostic criteria of OLP and oral lichenoid lesion. Results: DIF were classified by deposition intensity or pattern of anti-human antibody and fibrinogen. The classification of fluorescence pattern in each specimen was graded as positive, possibly positive or negative. Conclusions: Both CTO and CCW had positive and possibly positive pattern. Prevalence of positive pattern was 68.8% in CTO and 52.6% in CCW and that of possibly positive pattern was 9.4% in CTO and 5.3% in CCW. Prevalence of negative was 21.8% in CTO and 42.1% in CCW.