• 한국조경학회지
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• 제35권2호통권121호
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• pp.71-80
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• 2007

Korea began preserving and managing natural monuments in 1933 under Japanese Colonization, but North Korea and South Korea were forced to establish separate natural monument management policies because of the division after the Korean Independence. The purpose of this study is to compare and analyze the natural monument management policies of both south and North Korea between 1933 and 2005 to introduce new policies for Korea unification. The following are the results: First, South Korea manages every type of cultural asset, including natural monuments, through the 'Cultural Heritage Protection Act,' whereas North Korea managing its cultural assets through the 'Cultural Relics Protection Act' and the 'Landmark/Natural Monument Protection Act.' Second, South Korea preserves and utilizes natural monuments for the purpose of promoting the cultural experience of Korean people and contributing to the development of world culture, whereas North Korea uses its natural monuments to promote the superiority of socialism and protect its ruling power. Third, North and South Korea have similar classification systems for animals, plants, and geology, but North Korea classifies geography as one of its natural monuments. Unlike South Korea, North Korea also designates imported animals and plants not only for the preservation and research of genetic resources, but also for their value as economic resources. Fourth, North Korea authorizes the Cabinet to designate and cancel natural monuments, whereas South Korea designates and cancels natural monuments by the Cultural Heritage Administration through the deliberation of a Cultural Heritage Committee. Both Koreas' central administrations establish policies and their local governments carry them out, while their management systems are quite different. In conclusion, it is important to establish specified laws for the conservation of natural heritages and clarified standards of designation in order to improve the preservation and management system and to sustain the diversity of natural preservation. Moreover it is also necessary to discover resources in various fields, designate protection zones, and preserve imported trees. By doing so, we shall improve South Korea's natural monument management policies and ultimately enhance national homogeneity in preparation for the reunification of the Koreas in the future.

• Toxicological Research
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• 제33권1호
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• pp.49-54
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• 2017

Vitamin D3 is a fat-soluble secosteroid responsible for enhancing intestinal absorption of calcium, iron, and other materials. Vitamin D3 deficiency, therefore, can cause health problems such as metabolic diseases, and bone disorder. Female sex hormones including estrogen and progesterone are biosynthesized mainly in the granulosa cells of ovary. In this study, we isolated granulosa cells from porcine ovary and cultured for the experiments. In order to examine the effect of vitamin D3 on the ovarian granulosa cells, the mRNA and protein levels of genes were analyzed by real-time PCR and Western blot assay. The production of estrogen from the granulosa cells was also measured by the ELISA assay. Genes associated with follicle growth were not significantly altered by vitamin D3. However, it increases expression of genes involved in the estrogen-biosynthesis. Further, estrogen concentrations in porcine granulosa cell-cultured media increased in response to vitamin D3. These results showed that vitamin D3 is a powerful regulator of sex steroid hormone production in porcine granulosa cells, suggesting that vitamin D deficiency may result in inappropriate sexual development of industrial animals and eventually economic loss.

• 한국환경보건학회지
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• 제28권5호
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• pp.13-21
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• 2002

This study analyzed the characteristic of basic river structure, a flood level, the tree planting recommendation and syn thetic design, in order to establish a basic plan for preparing a natural practical area of environmental ecosystem at Bukchun and its surroundings. It was also investigated based on the opinion of citizens, geographical condition and the equipment/utilization examination of Bukchun which were included ecological circumstances, and thus provided a composite item for managing the natural river. This study also considered the development of the river in terms of culture, environment and ecology concept. The results were summarized as followed. Bukchun showed that the speed of a funning fluid is very fast on a period of flood. but very slow in a period of water shortage about 0.02 m/s. To prevent the speed change of a running fluid by a steep slope in a riverbed, there established Dongchun sluice gates under a bridge, including three sluice gates under a bridge, but there occurred extremely a riverbed erosion and corrosion section. The result of comparison between real flood degree and prediction flood data, there should perform a countermeasure the riverbed structure regulation of this area. Also, it was needed an exhaustive flood management in summer. According to the Bukchun and Hyungsangang riverbed investigation, there were needed preparation for natural/practical area and ecology Park development in the future. This study was investigated tree Planting/flower/blossom around the Bukchun and its surroundings. It was recommended willow, Italian poplar, bamboos and cherry blossoms in the Hyungsangang and Bukchun. There exist together historical space, environment space iud have enough possibility both natural learning space and civil rest space. And, it is possible to compose ecology natural learning and experimental area.

• 에너지공학
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• 제22권2호
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• pp.128-135
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• 2013

산지마다 상이한 성분을 갖는 천연가스의 가스호환성 및 연소특성을 판정하기 위해서는 많은 시간과 비용이 소비되고 그 범위도 넓어 어려움이 있어, 천연가스를 모사하는 등가가스를 대체하여 사용하는 방법이 사용되고 있다. 등가가스는 천연가스와 발열량, 압축계수, 상대밀도, CO 배출농도 및 연소속도에 차이가 거의 없다고 알려져 있지만, 실제 가스기기에 대한 화염형상, NOx 배출농도 및 효율에 대한 연구는 아직 보고되고 있지 않다. 본 연구에서는 천연가스를 모사하는 등가가스를 대상으로 기존에 보고된 CO 배출농도, 연소속도 및 화염온도 등을 재확인하고, 화염형상, NOx 배출농도 및 효율에 대해서 수치해석 및 실험을 통해 비교 검토함으로써 등가가스의 유효성을 검토하였다. 그 결과 천연가스와 등가가스의 차이는 미세하였으며, 등가가스를 이용하여 천연가스의 연소특성 및 호환성 범위를 검토하는데 문제가 없을 것으로 판단되었다.

• Natural Product Sciences
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• 제3권1호
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• pp.29-37
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• 1997

Protein Kinase C (PKC) is generally believed to play a central role in signal transduction, cellular growth control, gene expression, and tumor promotion. And it has been suggested that inhibitors of PKC might play important roles for the prevention and treatment of cancer. In order to investigate the possible inhibitors of PKC from natural products, PKC receptor binding assay was performed using bovine brain particulate as a source of PKC and the amount of $[^3H]Phorbol$ 12,13-dibutyrate (PDBu) bound to PKC was measured in the presence of test materials. Total methanol extracts from 100 kinds of natural products were partitioned into 3 fractions (n-hexane, ethyl acetate and aqueous layer) and their binding ability to the regulatory domain of PKC was evaluated. The ethyl acetate fractions of Morus alba $(roots,\;IC_{50}:\;156.6\;{\mu}g/ml)$, Rehmannia glutinosa $(roots,\;IC_{50}:\;134.3\;{\mu}g/ml)$, Lysimachia foenum-graecum $(roots,\;IC_{50}:\;167.8\;{\mu}g/ml)$, Polygonum cuspidata $(roots,\;IC_{50}:\;157.3\;{\mu}g/ml)$, Cnidium officinale $(aerial\;parts,\;IC_{50}:\;145.2\;{\mu}g/ml)$, and the hexane $(IC_{50}:\;179.3\;{\mu}g/ml)$ and the EtOAc fraction of Symplocarpus nipponicus $(roots,\;IC_{50}:\;155.9\;{\mu}g/ml)$ showed inhibitory activity of $[^3H]PDBu$ binding to PKC.

• Journal of Advanced Marine Engineering and Technology
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• 제38권5호
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• pp.589-601
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• 2014

Natural gas hydrate (NGH) is emerging as a new eco-friendly source of energy to replace fossil fuels in the 21st century. It is well known that the Natural Gas Hydrate contains large amount of natural gas about 170 times as much as its volume and it is easy to be stored and transported safely at about $-20^{\circ}C$ under atmospheric pressure due to so called "self-preservation effect". The option of gas transport by gas hydrate pellets carrier has been investigated and developed in various industry and academy. The natural gas hydrate pellet carrier is on major link in a potential gas hydrate process chain, starting with the extraction of natural gas from the reservoir, followed by the production of hydrate pellets and the transportation to an onshore terminal for further processing or marketing. In recent years, Korean project team supported by Korean Government has been working on the development of NGH total systems including novel NGH carrier since 2011. In order to increase the knowledge on the NGH pellet carrier developed and to understand the major hazards that could have significant impact on the safety of the vessel, this paper presents and evaluates the pros and cons of cargo holds, loading and unloading systems through the analysis of current patent technology. Based on the proven and well-known technologies as well as potential measures to mitigate sintering and minimize mechanical stress on the hydrate pellet in the self-preservation state, this study presents the conceptual and basic design for NGH carrier.

• 생약학회지
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• 제49권2호
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• pp.145-154
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• 2018

Aconiti Kusnezoffii Tuber has been traditionally used to treat the symptoms of rheumatoid arthritis and joint pain. The main constituents are diterpenoid alkaloids such as benzoylmesaconine, benzoylaconine, mesaconitine, aconitine, and hypaconitine. In Korea, Aconiti Kusnezoffii Tuber is officially defined as the tubers of Aconitum kusnezoffii Reichb., A. ciliare Decasisne, and A. triphyllum Nakai. On the other hand, only the tuber of A. kusnezoffii is to be used in China. In order to identify the botanical origin of Aconiti Kusnezoffii Tuber circulated in Korea, we analyzed 24 samples of Aconiti Kusnezoffii Tuber obtained from local markets for comparative DNA analysis. The sequence analysis of nrRNA ITS 1 was useful to distinguish Aconitum species and revealed that the roots of A. karakolicum were circulated in Korean markets without discretion. HPLC quantitative analysis showed that aconitine was detected at the highest amount in A. karakolicum. Authentic diterpenoid alkaloids were coinjected for quantification of aconitine-type ingredients. All data were statistically grouped by Principal Component Analysis (PCA). This study suggests that both molecular and chemical analyses should be utilized for the standardization and the quality control for Aconiti Kusnezoffii Tuber.

• 한국가스학회지
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• 제19권5호
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• pp.13-19
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• 2015

본 연구에서는 보다 현실적인 파쇄균열 전파를 묘사하기 위해 수압파쇄균열 전파 모델을 개발하였다. 이 모델에서는 두 가지 균열 전파 기준을 적용하였다. 첫 번째는 균열의 발생각을 결정하기 위한 최대 접선응력 기준과 두 번째는 파쇄균열의 자연균열 통과 여부 기준이다. 본 모델의 검증 결과, 수압파쇄균열이 자연균열을 통과하는 양상이 실험값과 동일함을 확인하였다. 균열의 전파에 직접적인 영향을 미치는 요소인 최대수평응력 방향, 균열면의 마찰계수, 자연균열의 방향성에 대한 민감도 분석 결과, 이론적 기준에 적합하게 균열의 전파 방향과 통과 여부가 결정되는 것으로 나타났다. 기존의 수직 판형 균열 전파 모델과 본 모델을 비교하여 균열의 연결성과 유정 자극부피 측면에서 차이가 있음을 확인하였다.

• Journal of Electrical Engineering and Technology
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• 제13권4호
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• pp.1682-1691
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• 2018

Natural ester is a suitable substitute for mineral oil and has been widely used in AC transformer in many countries. In order to further application of natural ester in direct current (DC) equipment, it is needed to investigate its long term insulation property under DC condition. In this paper, a thermal ageing experiment was conducted for both mineral oil-paper and natural ester-paper insulation. The DC breakdown and space charge characteristics of insulation paper impregnated with natural ester and mineral oil was compared. Results show that the resistivity of the paper immersed in natural ester and mineral oil both increase as the ageing goes on. While insulation paper impregnated with natural ester has higher resistivity and DC breakdown voltage than the paper impregnated with mineral oil. The DC breakdown voltage for the oil impregnated insulation paper being DC pre-stressing is higher than that without pre-stressing. The average DC breakdown field strength difference between the test with pre-stressing and without pre-stressing clearly shows that there is an apparent enhancement effect for the homo-charge injection on the DC breakdown.

• Advances in Traditional Medicine
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• 제1권2호
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• pp.45-51
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• 2000

This study was carried out to evaluate cytotoxicity of the methanol extract from Sophora flavescens Ait. against L1210 (lymphocytic leukemia) and $P388D_1$ (lymphoid neoplasma) Cells in vitro. We have determined cytotoxicity by the MTT (3- (4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H- tetrazolium bromide) assay. The order of cytotoxicity of Sophora flavescens Ait. extracts against L1210 and $P388D_1$ cells in vitro is as follows: Fr. 4 > Fr. 3 > Fr. 5 > Fr. 2 > Fr. 1. These results suggest that the fraction 4 of the methanol extracts from Sophora flavescens Ait. may be a valuable choice for the development of antitumor agents. In order to develop an antimicrobial agent, dried Sophora flavescens Ait. was extracted with hot methanol, and then antimicrobial activity (MIC test) was investigated. In this study, the fraction 3 of the methanol extracts from the roots of S. flavescens showed strong growth inhibition activity against gram-positive and gram-negative bacteria (MIC, $3.125\;{\mu}g/ml$) such as S. mutans, S. epidermidis and P. putida. These results indicate that fractions 3 and 4 inhibit tumor cells and bacteria.