• Archives of Pharmacal Research
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• 제21권4호
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• pp.391-397
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• 1998

The toxicity evaluation of oriental herbal drugs is of great concern at present. Bojungchisup-tang (BCST, in Korean), a decocted medicine of oriental herbal mixture, is now well used in clinic at oriental hospitals for the treatment of edema of several diseases in practice. However, the toxicity of the oriental herbal decocted medicines such as genetic toxicity is not well defined until now. In this respect, to clarify the genetic toxicity of BCST, in vitro chromosome aberration assay with Chinese hamster lung (CHL) fibroblasts and in vivo supravital micronucleus assay with mouse peripheral reticulocytes were performed in this study. In the chromosome aberration assay, we used 5,000 $\mu\textrm{g}$/ml BCST as maximum concentration because no remarkable cytotoxicity in CHL cells was observed both in the presence and absence of S-9 metabolic activation system. No statistical significant differences of chromosome aberrations were observed in CHL cells treated with 5,000, 2,500 and 1,250 $\mu\textrm{g}$/ml BCST for 6 hour both in the presence and absence of S-9 metabolic activation. However, very weak positive result (6.5-8.0% aberration) of BCST was obtained in the absence of S-9 metabolic activation system at 5,000 $\mu\textrm{g}$/ml BCST when treated for 24 hour, i.e. 1.5 normal cell cycle time. And also, in vivo clastogenicity of BCST was studied by acridine orange-supravital staining micronucleus assay using mouse peripheral reticulocytes. We used 2,000 mg/kg as the highest oral dose in this micronucleus assay because no acute oral toxicity of BCST was observed in mice. The optimum induction time of micronucleated reticulocytes (MNRETS) was determined as 36 hours after oral administration of 2,000 mg/kg BCST. No significant differences of MNRETs between control and BCST treatment groups were observed in vivo micronucieus assay. From these results, BCST revealed very weak positive result in chromosome aberration assay in vitro with CHL cells and no clastogenicity in micronucieus assay in vivo.

• Journal of the Korean Data and Information Science Society
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• 제23권4호
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• pp.787-796
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• 2012

본 연구의 목적은 PAPS를 실시하여 4, 5급에 해당하는 저체력군 학생을 대상으로 16주 복합운동프로그램을 통해 대사증후군과 자율신경계에 어떠한 변화가 나타나는가를 규명하는 것이다. 16주 복합운동프로그램은 주 5회에 걸쳐 준비운동, 본운동, 정리운동으로 구성하고 1회 50분씩 실시하였다. 자료처리는 SPSS 19.0 통계프로그램을 이용하여 모든 종속변인들의 평균과 표준편차를 산출하였다. 샤피로-윌크 검정값을 이용하여 정규성 검정을 실시하였고, 복합운동집단과 통제집단의 모평균 차이를 위하여 독립표본 t-검정을 실시하였으며, 16주 복합운동프로그램 전 후 각 집단 내변인들의 변화를 알아보기 위해 대응표본 t-검정을 실시하였다. 모든 통계치의 유의수준은 ${\alpha}$=.05로 처리하여 다음과 같은 결과를 얻었다. 본 연구 결과 대사증후군 지표에서는 허리둘레, 중성지방, 공복혈당, HDL-C에서 유의한 차이를 나타냈고, 자율신경계 요인에서는 통계적으로 모두 유의한 차이가 나타나 저체력군 고등학생에 긍정적인 영향을 미친 것으로 사료되어 진다.

• Restorative Dentistry and Endodontics
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• 제24권2호
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• pp.381-391
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• 1999

A new 5th generation adhesive system(ONE-STEP) has been supplied which operators can apply to conditioned tooth surfaces by one simplified step. The purpose of this study was to determine whether different methods of adhesive application and various air drying duration after applying adhesive affect the shear bond strength of composite resin to dentin, and to evaluate the adhesive pattern of composite resin and dentin under SEM. Seventy-seven extracted human molar teeth were cleaned and mounted in palstic test tubes. The occlusal dentin surfaces were exposed with Diamond Wheel Saw and smoothed with Lapping and Polishing Machine (South Bay Technology Co., U.S.A.). Teeth were randomly divided into 7 groups (n=11), In experimental A group, adhesive was applied to dentin with agitation for 20 sec. In experimental N-A group, adhesive were continuously applied to dentin for 20 sec. Also control and experimental 1, 2, 3, 4 groups were dried for 10, 0, 5, 20, 30 seconds after applying adhesive, respectively, Adhesives were light cured for 10 sec. A gelatin capsule 5mm in diameter was filled with Aelitefil$^{TM}$ composite resin, placed on the treated dentin surface and light cured for 40 see, from three sides, All specimens were stored in distilled water at room temperature for 24 hours. The shear bond strengths were measured using a universal testing machine(AGS-1000 4D, Japan) at a crosshead speed of 5mm/min. An one-way ANOVA and LSD test were used for statistical analysis of the data. For SEM evaluation, seven specimens were made and sectioned. Representive postfracture and seven specimens were mounted on brass stubs, sputter-coated with gold and observed under SEM. The results were as follows : 1. The shear bond strength of experimental A group which adhesive were applied to dentin with agitation was higher than that of experimental N-A group (continuous application), and there was significant difference between two groups (p<0.01). 2. The interface between composite and dentin according to different application methods showed close adaptation in experimental A group and showed tinny gap in experimental N-A group. 3. The shear bond strength accoding to various air drying duration was the lowest value(7.57${\pm}$2.60 MPa) in experimental 1 group, so there was significant difference between experimental 1 group and other four groups (p<0.05). But there was no significant difference of shear bond strength between four groups (p>0.05). 4. The interface between composite and dentin according to various air drying duration showed close adaptation in control group and tinny gap in experimental 3 and 4 groups. But experimental 1 and 2 groups showed $30{\mu}$ and 6 - $10{\mu}m$ thick gaps, respectively.

• 유통과학연구
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• 제13권1호
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• pp.83-91
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• 2015

Purpose - Despite the structural irrationality of multi-level transportation and the oil price rise, the domestic freight transportation market continues to grow, mirroring the rise in e-commerce and resultant increase in courier services and freight volumes. Several studies on courier services have been conducted. However, few studies or statistics have been published regarding regular freight services although they have played a role in the freight service market. The present study identifies the characteristics of regular freight service users to seek competitiveness enhancement measures specific to regular freight services. Research design, data, and methodology - IPA is a comparative analysis of the relative importance of and satisfaction with each attribute simultaneously. This study used IPA because it facilitates the process of analyzing importance and performance, deriving implications and a visual understanding of results. To enhance the competitiveness of regular freight services, this study surveyed its current users regarding the importance of the regular freight service factors. A total of 200 copies of a questionnaire were circulated and 190 copies were returned. In addition to demographics, respondents answered questions about the importance of and satisfaction with services on a 5-point Likert scale. Excluding 3 inappropriate copies, 187 out of 190 copies were analyzed. PASW Statistics 18 was used for statistical analysis. A total of 20 question items were selected for the service factors presented in the questionnaire based on the 1st pilot survey and previous studies. Results - According to the IPA performed to compare the importance of and satisfaction with service factors, both importance and satisfaction are high in the 1st quadrant, which involves the economic advantage of using regular freight services, quick arrival at destinations, weight freight handling, and less time constraints on freight receipt/dispatch. This area requires continuous management. Satisfaction is higher than importance in the 2nd quadrant, which involves the adequacy of freight, cost savings over ordinary courier services, notification on freight arrival, and freight tracking information. This area requires intensive investment and management. Satisfaction is lower than importance in the 3rd quadrant, involving the credit card payment system, courier delivery service, distance to freight handling sites, easy access to freight handling sites, and prompt problem solving. This area requires further intensive management. Both importance and satisfaction are low in the 4th quadrant, involving the availability of collection service, storage space at freight handling sites, kindness of collection/delivery staff, kindness of outlet staff, and easy delivery checks. This area is a set of variables should be excluded from priority control targets. Conclusions - Based on the IPA, service factors that need priority controls because of high importance and low satisfaction include the credit card payment system, delivery service, distance to freight handling sites, easy access to freight handling sites, and prompt problem solving. The findings need to be applied to future marketing strategies for regular freight services and for developing competitiveness enhancement programs.

• Bulletin of the Korean Chemical Society
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• 제7권5호
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• pp.367-371
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• 1986

Dynamic and equilibrium properties of n-alkane chains immersed in solvent molecules have been investigated by a molecular dynamics method. The n-alkane chain is assumed to be a chain of elements (CH$_2$) interconnected by bonds having a fixed bond length and bond angle, but each bond of the chain is allowed to execute hindered internal rotation. We studied the effect of the number of the chain elements (N$_c$ = 10, 15 and 20) on the equilibrium properties of the system, e.g., the pair correlation functions between a chain element and solvent molecules, g$_{cs}$(r), and between the chain elements, g$_{cc}$(r), and the configurational properties such as the mean-square end-to-end distance < R$^2$ >, the mean-square radius of gyration < S$^2$ >, and the eigenvalues of the moment-of-inertia tensor < S$_i^2$ > / < S$^2$ > (i = 1, 2 and 3). We also studied the dynamic properties of the system, e.g., the autocorrelation function C(A;t) where A = R$^2$(t), = S$^2$(t), or = ${\vec{V}}(t)({\vec{V}}$ = velocity of the center of mass), and the diffusion coefficient D. The g$_{cs}$(r)'s are almost equal irrespective of the change of Nc while g$_{cc}$(r) becomes larger as N$_c$ increases; The MD computed configurational properties < R$^2$2 > and < S$^2$ > were found to be a little different from the values calculated from the statistical equations of < R$^2$ > and < S$^2$ >, it may be due to the fact that our model for the MD simulations includes a long-range volume effect. From the < S$_i^2$ > / < S$^2$ >, it is found that the chain molecule has a nearly spherical shape irrespective of the variation of N$_c$. For the dynamic properties we found that the C(R$^2$;t) and C(S$^2$;t) of lower N$_c$ decay faster than those of higher N$_c$, while the C($\vec V$;t) of the center of mass in the chain is weakly dependent on the N$_c$. The center of mass diffusion coefficient D$_c$ decreases as N$_c$ increases while the end point diffusion coefficient D$_e$ is nearly equal irrespective of the change of N$_c$.

• 한국지구과학회지
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• 제38권4호
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• pp.269-282
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• 2017

이 연구에서는 Earth Observing System Terra 위성에 탑재된 Moderate Resolution Imaging Spectroradiometer (MODIS) 협대역 방출율(채널 29, 30, 31) 자료와 다중선형회귀모형을 이용하여 지표면 광대역 방출율을 추정하였다. 다중선형회귀모형 도출 및 검증을 위한 분광 방출율 자료는 MODIS University of California, Santa Barbara와 Advanced Spaceborne Thermal Emission and Reflection Radiometer spectral library의 307종(토양 123종, 식생 32종, 물 19종, 인위적 재료 43종, 바위 90종)을 사용하였다. 도출된 다중선형회귀모형의 결정계수($R^2$)는 0.95 (p<.001)로 높게 나타났고 또한 이 모형 결과와 이론적 광대역 방출율 값의 평균제곱근오차(Root Mean Square Error)는 0.0070이었다. 그리고 이 연구 결과에 따라 계산된 지표면 광대역 방출율을 선행 연구 Wang et al. (2005)의 결과와 비교하였다. 그 결과 아시아, 아프리카, 오세아니아 지역에서 이 연구와 Wang et al. (2005)의 결과에 대한 1월 평균 지표면 광대역방출율의 평균제곱근오차는 0.0054이었고 최소와 최대 편차는 각각 0.0027과 0.0067이었으며 이러한 통계 값은 8월에도 유사하였다. 이 연구에서 다중선형회귀모형에 의하여 계산한 지표면 광대역 방출율은 Wang et al. (2005)의 값과 큰 차이가 없이 비교적 정확하게 산출되었으나 산출 정확성 향상을 위해서는 토지피복특성에 따른 차별화된 회귀모형 적용 필요성이 제기된다.

• 해양환경안전학회지
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• 제19권4호
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• pp.345-351
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• 2013

IWRAP 프로그램은 수로에서의 위험성을 평가하는데 유용한 프로그램이다. 그러나 이 프로그램의 기본 버전의 경우 AIS 데이터를 수집하는 기능이 포함되지 않아서, 더구나 베트남과 같은 개발도상국에서는 해상교통량 통계 데이터가 없는 실정이다. 사용자들은 수동으로 준비하여 입력하여야 한다. 이 연구는 IWRAP Mk2 프로그램 기본 버전을 사용하는데 있어 AIS 데이터를 전처리(pre-process) 할 수 있는 프로그램을 개발하고자 하였으며, 선박 형태, 선박 크기, 통과 시간 등으로 분류한 통항로에서의 선박 통항 척수 및 항로 배치와 같이 해역 내 해상교통에 관한 정보들을 사용자에게 제공하도록 고안되었다. 이렇게 개발된 통합 AIS 프로그램(Total AIS, TOAIS)은 베트남 Vung Tau 해역의 AIS 수집 데이터를 전처리할 수 있는지에 대하여 검증하였다. 그 결과, 통합 AIS 프로그램에서 전처리한 데이터를 이용한 IWRAP 프로그램은 베트남 해역의 위험성을 효율적으로 평가할 수 있었다.

• 한국방재안전학회논문집
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• 제12권3호
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• pp.25-34
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• 2019

현대의 재난은 재난에 대해서 사전에 사고를 미리 예방하는 것도 사고 이후 복구도 매우 중요하다. 이러한 사고에 대한 현재 우리 정부의 대처방법은 적절하지 못하고 있다. 현재까지는 재난관리에 대해서는 재난에 대한 대응과 복구 활동의 중심이었으며, 그것에 대해 정부가 주도해 왔다. 반면에 대부분의 민간단체 및 기관들은 정부 재난관리 기관들을 보조만 해 왔던 것이 현실이었다. 우리나라도 이젠 지진 안전지대라고 할 수는 없다. 지진에 대비한 효과적인 재난관리체계의 확립을 위하여 현재 우리나라의 지진대비 재난관리 운영상의 문제점이 매우 시급하며, 이를 개선하기 위한 정책적 대안을 모색하려는 학문적 노력은 시기적으로 또 내용적으로 필요성이 매우 크다고 할 수 있다. 본 연구는 2016년에서부터 2019년 사이에 일어난 지진에 대해 통계청 자료를 근거로 하여 분석해 보았다. 먼저 연구문제 1: 포항지진에 대한 정부의 대책은 어떠했는가?에 대한 결과에서는 포항지진에서는 주민대피도 중요했지만, 일주일 연기된 수능 일에는 학생들 안전을 위하여 직접 고사장에 배치되어 직접 현장에서 긴급 상황에 대비하여 수능에 차질없이 대처하였다. 따라서 연구 분석 결과 우리나라는 이러한 국가적 재해에 대비하여 앞으로도 재난 현장에서 피해 원인과 대응에 대하여 고민하고 피해를 최소화 시킬 수 있는 기술과 방법을 개발하기 위하여 끊임없이 노력해야 할 것이다.

• 한국환경농학회지
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• 제17권4호
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• pp.352-357
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• 1998

양액조성의 차이에 따른 토마토의 오존 감수성을 구명하고자 1/2농도의 Hoagland 용액을 표준으로 하여 양액을 조성하였다. N-P-K의 수준을 $N_{100}$ $P_{100}$ $K_{100}$(대조구), $N_{47}$ $P_{100}$ $K_{100}$(질소 감량구), $N_{93}$ $P_0$ $K_{100}$(인산 제거구), $N_{100}$ $P_{100}$ $K_0$(칼륨 제거구), $N_{153}$ $P_{100}$ $K_{100}$(질소 중량구), $N_{107}$ $P_{200}$ $K_{100}$(인산 2배구), $N_{140}$ $P_{100}$ $K_{200}$(칼륨 2배구) 등으로 나누어 수경재배한 후 $0.25{\mu}l/L$의 오존에 접촉시킨 결과 다음과 같은 결론을 얻었다. 1. 지상부 생육은 질소 감량구와 인산 제거구에서 가장 저조하였고, 인산 및 갈륨 제거구에서 인산가 칼륨의 엽중함량이 극히 낮았다. 시비수준의 차이에 따른 가시피해율은 칼륨 제거구에서 가장 심하게 나타났다. 인산 제거구, 질소 감량구 및 중량구 또는 인산과 칼륨 2배구의 피해율은 표준구와 비슷한 경향을 보였다. 2. 오존접촉 후 칼륨 제거구에서 다른 처리구에 비하여 ethylene발생량, 전해질 유출량과 MDA함량이 증가하였으며 엽록소의 함량은 크게 감소였다. 3. 가시피해가 가장 심했던 칼륨 제거구에서 SOD의 활성이 가장 낮았으며 오존접촉 후에도 활성 증가율이 가장 낮게 유지되었다.

• 패션비즈니스
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• 제12권4호
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• pp.28-45
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• 2008

The purpose of this study is to diagnose actual condition of preference of hair-styling, hair-styling techniques, management, grasping a consumer's consciousness, etc with women living in a city. The survey was gotten to a feminine customer who visited the ten of beauty-shops in shopping center. And statistical data about the actual condition of hair-styling preference realities, hair-styling method and style management was entered into the SPSS statistics analysis system. In brief, be as follows by the results of study. There showed significant difference that noted in hair-style information and basis alternative a beauty salon, there were able to know people whose age is from 20's to 40's got mainly an influence of public media very much and from 40's to 50's got mainly an influence of people around them. Basis alternative of a beauty salon showed significant difference to follow age categories. It appeared that introducing from people around them have a effect on the 20's and 30's, and 40's got an influence of convenience of traffic, and 50's got mainly the shortest distance. In an attitude toward a hair style, especially toward hair cut, a case to do hair cut was most a lot of in own selections, and its result was independent of age categories. The reason that wants to give a chance was most a lot of thinking without an age. Preference length of hair cut showed a significant difference according to age. In permanent section, own selections appeared most regardless of age. And in the permanent motive, also, to have a change appeared most regardless of age. And people had a preference natural to role up to setting regardless of age in permanent wave. In hair color section, women whose age is 20's, 30's, 40's had a motive for a change, on the other hand, 50's and their senior had a motive for a gray hair. Women of all over the age almost knew a fashion color, and they had a preference brown color. In a preference way along a hair color kind, there was a significant difference according to age, also. 20's and 30's did mainly 'semi-permanent coating' and 40's and 50's did mainly 'permanent hair color'. In a attitude about a hair-style management, the more age is young, the more a period is long term. And the more age is old, the more the outlay for price of cut is expensive. But, on the contrary, permanent price showed that the more age is young, the more the outlay for price of permanent is expensive. In hair color, the more age is old, the more a period is short and the more price is low.