• Title/Summary/Keyword: national integration

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Transformation of Pleurotus sajor-caju by Complementation of PABA Requiring Mutant (여름 느타리버섯에서 PABA 변이주의 Complementation에 의한 형질전환)

  • Byun, Myung-Ok;Chung, Jong-Chun;You, Chang-Hyun;Cha, Dong-Yeul;Lee, Du-Hyung
    • The Korean Journal of Mycology
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    • v.25 no.3 s.82
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    • pp.233-237
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    • 1997
  • A PABA auxotroph of Pleurotus sajor-caju were transformed to prototrophy by using a plasmid containing pab 1 gene from Coprinus. The efficiencies of transformation of Pleurotus sajor-caju was five transformants per ${\mu}g$ of plasmid DNA. Southern blot analysis of DNA extracted from transformants demonstrated that plasmid DNA was integrated into the chromosomal DNA in multiple tandem copies. Progenies of heterokaryons between transformants of PABA and other auxotropic strains produced pab-progeny, which indicated that integration occurred at a site(s) other than the resident pab biosynthetic gene.

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Evaluation of Machine Learning Methods to Reduce Stripe Artifacts in the Phase Contrast Image due to Line-Integration Process (선적분에 의한 위상차 영상의 줄무늬 아티팩트 감소를 위한 기계학습법에 대한 평가)

  • Kim, Myungkeun;Oh, Ohsung;Lee, Seho;Lee, Seung Wook
    • Journal of the Korean Society of Radiology
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    • v.14 no.7
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    • pp.937-946
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    • 2020
  • The grating interferometer provides the differential phase contrast image of an phase object due to refraction of the wavefront by the object, and it needs to be converted to the phase contrast image. The line-integration process to obtain the phase contrast image from a differential phase contrast image accumulates noise and generate stripe artifacts. The stripe artifacts have noise and distortion increases to the integration direction in the line-integrated phase contrast image. In this study, we have configured and compared several machine learning methods to reduce the artifacts. The machine learning methods have been applied to simulated numerical phantoms as well as experimental data from the X-ray and neutron grating interferometer for comparison. As a result, the combination of the wavelet preprocessing and machine learning method (WCNN) has shown to be the most effective.

A Data Cleansing Strategy for Improving Data Quality of National R&D Information - Case Study of NTIS (데이터 품질을 고려한 국가R&D정보 데이터베이스의 통합 사례 연구 - NTIS 데이터베이스 통합 사례)

  • Shin, Sung-Ho;Yoon, Young-Jun;Yang, Myung-Suk;Kim, Jin-Man;Shon, Kang-Ryul
    • Journal of the Korea Society of Computer and Information
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    • v.16 no.6
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    • pp.119-130
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    • 2011
  • On the point of data quality management, data quality is influenced by quality policy, quality organization, business process, and business rule. Business rules, guide of data manipulation, have effects on data quality directly. In case of building an integration database among distributed databases, defining business rule is more important because data integration needs to consider heterogeneous structure, code, and data standardization. Also data value has various figures depended on data type, unit, and transcription. Finally, database structure and data value problem have to be solved to improve data quality. For handling them, it is needed to draw database integration model and cleanse data in integrated database. NTIS(stands for National science and Technology Information Service) has an aim to serve users who need all information about national R&D by internet, and for that aim, it has a integrated database which has been made with several database sources. We prove that database integration model and data cleansing are needed to build a successful integrated database through NTIS case study.

Geologic Structure Analysis from the Integration of Magnetotelluric and Gravity Models at Hwasan Caldera (화산칼데라 지역 중력 및 자기지전류 탐사 자료의 복합해석을 통한 지질구조 해석)

  • Park, Gye-Soon;Oh, Seok-Hoon;Lee, Heui-Soon;Kim, Jung-Ho;Kwon, Byung-Doo
    • 한국지구물리탐사학회:학술대회논문집
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    • 2008.10a
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    • pp.21-26
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    • 2008
  • A multi-geophysical surveys were carried out at Hwasan caldera which is located in Euisung Sub-basin. In order to overcome the limitation of the previous studies, dense gravity data and magnetotelluric (MT) data were obtained and integrated. In this study, the independent inversion models from gravity and MT method were integrated using a correlation and classification approaches to map geologic structure. The results of integration analysis indicated followings; 1) pyroclastic rocks around the central area of Hwasan caldera have lower density and resistivity when compared with those of neighborhood regions and are extended to around 1 km in depth, 2) the high resistivity and density intrusive igneous rocks are imaged around the ring fault boundary, and 3) the basement structure, which has low resistivity and high density, 5 km deep inferred by integration analysis. Also, for integration analysis, we suggested Structure Index method. This method is analyzed using Type Angle and Type Intensity, which are calculated by the spatial correlation of the physical properties. In this study, we can perform the integration analysis effectively using Structure Index method.

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An XML Schema-based Semantic Data Integration (XML Schema기반 시맨틱 데이타 통합)

  • Kim Dong-Kwang;Jeong Karp-Joo;Shin Hyo-Seop;Hwang Sun-Tae
    • Journal of KIISE:Computer Systems and Theory
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    • v.33 no.9
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    • pp.563-573
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    • 2006
  • Cyber-infrastructures for scientific and engineering applications require integrating heterogeneous legacy data in different formats and from various domains. Such data integration raises challenging issues: (1) Support for multiple independently-managed schemas, (2) Ease of schema evolution, and (3) Simple schema mappings. In order to address these issues, we propose a novel approach to semantic integration of scientific data which uses XML schemas and RDF-based schema mappings. In this approach, XML schema al-lows scientists to manage data models intuitively and to use commodity XML DBMS tools. A simple RDF-based ontological representation scheme is used for only structural relations among independently-managed XML schemas from different institutes or domains We present the design and implementation of a prototype system developed for the national cyber-environments for civil engi-neering research activities in Korea (similar to the NEES project in USA) which is called KOCEDgrid (http://www.koced.net).

A Study on the Effects of Management Strategy, Collaboration Process and SCM Integration on Corporate Performance in Small and Midsize Parts Manufacturers (중소부품제조업체의 경영전략, 협업프로세스 및 SCM통합이 기업성과에 미치는 영향에 관한 연구)

  • Lee, Seol-Bin;Park, Ju-Gyeong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.7
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    • pp.448-466
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    • 2019
  • Today, companies are increasingly focused on SCM (Supply Chain Management) as a means for cost-cutting and efficient operation. The company's ultimate objective is to win and maintain a sustained dominant position in the uncertainties of the global environment and future competitiveness. In this respect, this study examined the effects of management strategy, collaboration process and SCM integration on corporate performance in small and midsize parts manufacturers. The results of empirical analysis are summarized as follows. Management strategy, collaboration process and SCM integration had positive effects on corporate performance in domestic small and midsize parts manufacturers, and all hypotheses were supported. Consequently, it can be confirmed that quality, cost and flexibility for management strategy, and strategic objective perception, support policy, problem solution and knowledge information sharing for delivery and collaboration as small and midsize parts manufacturers are mechanisms for improving quality reliability, decreasing cost, delivery obedience and information system operation of SCM integration, and boosting corporate quantitative and qualitative performance.

Issues in the Integration Education for North Korean Refugees and South Korean Hosts (새터민과 남한주민을 위한 문화통합교육의 과제)

  • Jean-Kyung Chung;Jung-A Cho
    • Korean Journal of Culture and Social Issue
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    • v.14 no.1_spc
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    • pp.487-518
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    • 2008
  • The study identifies the major themes for integration education program which enhances the relationship between the north Korean refugees and their south Korean hosts. The themes were selected based on qualitative analysis of the socio-cultural conflicts experienced by the refugees and the hosts in the acculturation process. Twenty-eight north Korean refugees over age 20 participated in semi-structured interviews, and two south Korean groups in close contact with the refugees, police and volunteer teachers, were interviewed in focus groups. The interviews were recorded and transcribed for categorization and coding. The study views the acculturation issue as the two-sided integration task for both the north Korean refugees and the south Korean hosts rather than as the one-sided acceptance and assimilation task for the refugees.

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A Study on the Combination of Vision-Based Displacement and Double Integration of Acceleration in Displacement Measurement of Bridge under Moving Load (주행 하중에 의한 교량 변위 계측에서 영상 변위와 가속도 이중 적분의 조합에 관한 연구)

  • Hyeong-Jin Lee
    • Journal of the Korean Society of Industry Convergence
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    • v.27 no.5
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    • pp.1069-1080
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    • 2024
  • Recently, vision-based displacement(VBD) has been attracting attention as a convenient and economical method. VBD has the advantage of being easy to install and operate, but it also has the disadvantage of being difficult to obtain results that reflect high-frequency characteristics well. On the other hand, indirect displacement measurement through double integration of acceleration may in some cases result in distortion in the low-frequency region, making integration itself impossible. Therefore, neither can be a suitable method alone for measuring the dynamic displacement of bridges under moving loads. In this context, this paper studies how to obtain more accurate dynamic displacement responses of bridges over the entire frequency range by combining two methods, VBD and acceleration integration. The practical applicability was examined through simulation and model experiments. The simulation results show that both basic methods have fundamental limitations in each frequency range, while the combined method can be an good alternative to overcome these limitations. The applicability of the combination method through model experiments also showed relatively good results, but the results were inferior to those in the theoretical case. The reason is that errors in each basic measurement methods are transferred to the combined method. In other words, it is important that the basic measurement method also secures sufficient accuracy at least in each advantageous frequency band. In conclusion, combining the strengths of different methods to create a better alternative is always a good approach, and the method in this paper is meaningful in that it demonstrates one such alternative.

Verbal Behaviors and Interactions in Processes of Making Written Test Items Using Paired Think Aloud Problem Solving for Pre-Service Secondary Chemistry Teachers (중등 예비 화학교사의 해결자·청취자 활동을 통한 지필평가 문항 제작 과정에서 언어적 행동 및 상호작용)

  • Kang, Hunsik
    • Journal of The Korean Association For Science Education
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    • v.38 no.5
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    • pp.611-623
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    • 2018
  • This study investigated verbal behaviors and interactions in the processes of making written test items using paired think aloud problem solving for pre-service secondary chemistry teachers. The processes of making written test items using paired think-aloud problem solving in four small groups consisting of two pre-service chemistry teachers were recorded and transcribed. The analysis of the results revealed that 'item making' for ten subcategories for solver's verbal behaviors were most frequently exhibited regardless of 'integration' among the components of pedagogical content knowledge (PCK). The solver's 'provide', 'modify', 'require agreement', 'ask', 'agree', and 'justify' were also frequently exhibited although fewer than 'item making'. Especially, the solver's 'ask' was more frequently used in 'non-integration', whereas 'justify' was more frequently used in 'integration'. In listener's verbal behaviors consisted of eight subcategories, 'point out', 'ask', and 'agree' were frequently exhibited regardless of 'integration'. Listener's 'ask' and 'agree' were exhibited more in 'non-integration', whereas 'point out' was exhibited more in 'integration'. Many verbal interactions were analyzed to be in 'symmetrical type' more than 'solver-dominant type' or 'listener-dominant type'. 'Symmetrical type' was also more frequently exhibited in 'integration', whereas 'solver-dominant type' was more frequently exhibited in 'non-integration'. There were little differences between 'integration' and 'non-integration' in 'listener-dominant type'. In 23 subcategories of 'symmetrical type', 'ask-provide' and 'point out-justify' were most frequently found. Especially, 'ask-provide' was more frequently found in 'non-integration', whereas 'point out-justify' was more frequently found in 'integration'. 'Point out-modify' was the most frequent in 4 subcategories of 'listener-dominant type', while 'item making-agree' in three subcategories of 'solver-dominant type' regardless of 'integration'. However, only a little of other subcategories of the three types were found.

Selection of Optimum Expression System for Production of Kringle Fragment of Human Apolipoprotein(a) in Saccharomyces cerevisiae

  • Cha Kwang Hyun;Kim Myoung Dong;Lee Tae Hee;Lim Hyung Kweon;Jung Kyung Hwan;Seo Jin Ho
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.9 no.6
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    • pp.523-527
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    • 2004
  • Recombinant Saccharomyces cerevisiae expression systems were developed to pro­duce a novel human anti-angiogenic protein called LK8, an 86 amino-acid kringle fragment pro­tein with three disulfide linkages. Galactose-inducible LK8 expression plasmid was constructed, and LK8 production levels by four S. cerevisiae strains were compared in order to select an op­timal host strain. S. cerevisiae 2805 was the most efficient among the strains tested. Elevating the LK8 gene copy number through multiple integration using 8-sequences as target sites re­sulted in more than a two-fold increase in the LK8 production level compared with the plasmid­based expression system. The maximum LK8 protein concentration of 25 mg/L was obtained from batch cultivation of the yeast transformant that harbors 16 copies of the LK8 gene. In con­clusion, the strain integrated with the multiple LK8 gene secreted the protein with relatively high yield, although, the increased LK8 gene dosage over 11 copies did not lead to further en­hancement in batch cultivations.