• Title/Summary/Keyword: mycosis

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A Case of Mycosis fungoides Confirmed by Electron Microscopy (전자현미경 검사에 의해 확진된 균상식 육종(Mycosis fungoides) 1예)

  • Kwon, T.J.;Kim, C.S.;Lee, Y. B.
    • Applied Microscopy
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    • v.12 no.1
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    • pp.41-47
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    • 1982
  • Mycosis fungoides is an uncommon, chronic fatal disease of lymphoreticular system associated with primary ski3 involvement for many years and terminating as a malignant lymphoma with involvement of lymph nodes and viscerae. On occasion it simulates numerous other nonspecific benign skin lesions, thus it may be impossible to decide whether the infiltrate represents early mycosis fungoides or nonspecific on the histopathologic ground alone. A case of mycosis fungoides was confirmed by electron microscopy and reported here. The patient was 69-years-old male who had suffered from erythematous scaly eruption on the whole body since 10 years. Skin biopsies of 4 times showed focal ulceration with chronic nonspecific inflammation and polymorphic cell infiltration in lower dermis, thus possibility of mycosis fungoides could not be completely ruled out. Electron microscopically several atypical lymphoid cells, which had a large cerebriform nucleus with peripheral condensation of dense chromatin and scant cytoplasm, were noted in the upper dermis. Intraepidermal infiltration of these atypical cells was also seen. It was thought that the electron microscopic study may be very helpful to differentiate equivocal mycosis fungoides from the nonspecific dermatosis.

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Pulmonary Mycosis (report of two cases) (폐진균증(肺眞菌症) -2례(例) 보고(報告)-)

  • Han, Sung See;Lee, Sung Koo;Lee, Sung Haing
    • Journal of Chest Surgery
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    • v.9 no.2
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    • pp.161-168
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    • 1976
  • It has been known which the pulmonary mycosis usually results from secondary invader of preexisting bronchopulmonary diseases, e.g. pulmonary tuberculosis, bronchiectasis, abscess, cysts, or pulmonary malignancy and as the predisposing factor appears to be concerned with long-term therapy of several antibiotics, steroids, or chemotherapeutic agents, etc. Recently, it has been interested rather the diagnosis and pathogenesis of then pulmonary mycosis than the treatment, especially because of some difficulty of the diagnosis. The authors experienced too cases of the pulmonary mycosis which were treated onc case medically, as moniliasis and the other surgically, as aspergillosis. There was noticed that our pulmonary moniliasis developed probably due to long-term therapy of antibiotics and aspergillosis resulted from secondary invader in the previous cyst of bronchiectasis.

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Pulmonary Mcosis (폐진균증)

  • 임병화;홍완일;김의윤
    • Journal of Chest Surgery
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    • v.6 no.1
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    • pp.29-36
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    • 1973
  • It has been known that the pulmonary mycosis generally results from saphrophytic colonization of pre-existing lung cavities, e.g. , due to pulmonary tuberculosis, abscess, bronchiectasis. or congen-ital cysts. Recently, the authors experienced four cases of the pulmonary mycosis which were all treated surgically, and in our opinion, three of them were considered to arise from secondary saphrophytic colonization of pre-existing tuberculous cavities by serial chest roentgenograms. One of them was actinomycosis which was known as relatively rare pulmonary mycosis, and its clinical experience was previously reported. The purpose of this report is mainly to review our clinical experience and some related literatures with three patients with aspergillosis. Many writers have stressed the sputum culture for aspergillus, immunologic study and serial roentgenographic findings were all important or essential in diagnosing aspergillosis. Surgical resection appears to be the treatment of choice for the mycosis of lung, and systemic administration of effective anti-fungal agents such as amphotericin B for aspergillosis and penicillin for actinomycosis respectively following surgical intervention is usually necessary to eradicate completely.

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Mycosis Fungoides Responsive to Oral Alitretinoin and Ultraviolet B Phototherapy: A Case Report

  • Han, Song Hee;Hong, Ji Youn;Hong, Joo Ran;Hur, Min Seok;Youn, Hae Jeong;Lee, Yang Won;Choe, Yong Beom;Ahn, Kyu Joong
    • Korean journal of dermatology
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    • v.56 no.10
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    • pp.636-639
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    • 2018
  • Mycosis fungoides is the most common type of cutaneous T-cell lymphoma. Patients with early stage disease usually respond well to conventional therapies, with a relatively favorable prognosis. However, a few patients are refractory to treatment and need alternative strategies, even at the patch and plaque stages. We report the case of a middle-aged woman with long-standing and refractory mycosis fungoides that responded to combination therapy with the 308-nm excimer laser and oral alitretinoin.

Two Cases of Guttural Pouch Mycosis in Race Horses Caused by Aspergillus nidulans (Aspergillus nidulans의한 경주마의 후당염 2예)

  • Ha Tae-young;Cho Gil-jae;Bak Ung-bok;Kim Sang-jae
    • Journal of Veterinary Clinics
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    • v.12 no.1
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    • pp.853-860
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    • 1995
  • Two cases of guttural pouch mycosis in race horses were observed for clinical and pathological aspects of the disease to investigate etiology and pathogenesis of dysphagia and epistaxis of the horse. In case 1 showing prolonged dysphagic sign a diphtheritic membrane was confined to the guttural pouch involved with neuritis of the glossopharyngeal nerve due to fungal penetration. The other horse showing fatal recurrent epistaxis had lesion of mycetoma invading the internal carotid artery to provoke erosion of the artery. An Aspergillosis sp. was isolated from the guttural pouches of the two horses and identified as A nidulans.

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Impact of Fungus on Egg Shell of Tropical Tasar Silk Worm, Antheraea mylitta: An Ultra-structural Approach

  • Barsagade, Deepak Dewaji;Pankule, Sushama Dilip;Tembhare, Dnyaneshwar Bapuji
    • International Journal of Industrial Entomology and Biomaterials
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    • v.18 no.2
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    • pp.77-82
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    • 2009
  • The egg shell of the tropical tasar silkworm, Antheraea mylitta is formed from the substances secreted by the follicular epithelium during the late vitellogenic stage. TEM study reveals the inner travecular and outer lamellar layer of chorion. The travecular layer is composed of the innermost wax layer, inner and outer chorionic layer. The inner and outer chorionic layers are connected to each other by vertical pillers forming of cavities. The lamellar layer is perforated by the aeropyles. SEM study reveals the differentiation of an anterior surface of the egg shell into four zones-micropylar, edge, aeropyles crown and disc zone. In the mycosis infected eggs the aeropyles and egg-shell surface are fully packed with the hyphae of the fungus, Aspergillus sydowi blocking of plastron respiration and causing the death of developing embryo so that mycosis infected eggs become sterile.

Clinical outcomes and prognostic factors in patients with mycosis fungoides who underwent radiation therapy in a single institution

  • Jang, Bum-Sup;Kim, Eunji;Kim, Il Han;Kang, Hyun-Cheol;Ye, Sung-Joon
    • Radiation Oncology Journal
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    • v.36 no.2
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    • pp.153-162
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    • 2018
  • Purpose: We aimed to evaluate clinical outcomes including progression-free survival (PFS), overall survival (OS), partial response, and complete response in patients who underwent radiation therapy (RT) for mycosis fungoides (MF). Also, we sought to find prognostic factors for clinical outcomes. Materials and Methods: Total 19 patients confirmed with MF between 1999-2015 were retrospectively reviewed. Clinical and treatment characteristics, clinical outcomes, and and toxicities were analyzed. Results: Eleven patients were treated with total skin electron beam radiotherapy (TSEBT) and 8 patients with involved field radiation therapy (IFRT) with median dose of 30 Gy, respectively. The median time interval from diagnosis to RT was 2.6 months (range, 0.4 to 87.3 months). The overall response rate was 100%; 11 patients (57.9%) had a complete response and 8 patients (42.1%) a partial response. The presence of positive lymph node at the time of consultation of RT was associated with lower OS (p = 0.043). In multivariate analysis, PFS was significantly lower for patients with increased previous therapies experienced following RT (p = 0.019) and for patients showing PR during RT (p = 0.044). There were no reported grade 3 or more skin toxicities related with RT. Conclusion: Both IFRT and TSEBT are effective treatment for MF patients. Patients with short disease course before RT or complete response during RT are expected to have longer PFS. Positive lymph node status at the initiation of RT was associated woth poor OS, suggesting other treatment modalities such as low-dose RT for patients with low life-expectancy.

Unidentified Mycosis of Kelp Saccharina japonica Gametophytes (다시마(Saccharina japonica) 배우체의 미동정 진균증)

  • Jeong, Ha-Na;Oh, Myung-Joo;Choi, Sung-Je;Seo, Jung-Soo;Park, Myoung-Ae;Kim, Wi-Sik
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.50 no.2
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    • pp.219-221
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    • 2017
  • In 2015, white cottony tufts were observed on gametophytes of the kelp Saccharina japonica. Wet mount and histopathology examination revealed numerous fungal hyphae and mycelium around the gametophytes. The gametophytes surrounded by fungal hyphae were generally round and empty. A specific 610-bp fragment of the internal transcribed spacer (ITS)-5.8S rDNA-ITS gene of fungi was amplified by polymerase chain reaction and the nucleotide sequence showed 100% identity with those of Acremonium sclerotigenum, Acremonium sp. and Ascomycota sp. When fungus-infected gametophytes were mixed with healthy gametophytes, a high transmission rate (100%) resulted. This is the first report of mycosis of gametophytes in Korea.

Dosimetry for Total Skin Electron Beam Therapy in Skin Cancer (피부암치료를 위한 전자선 전신피부 치료방법과 선량분포 측정)

  • Chu, Sung-Sil;Loh, John-Jk;Kim, Gwi-Eon
    • Radiation Oncology Journal
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    • v.10 no.1
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    • pp.107-113
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    • 1992
  • Increasing frequency of skin cancer, mycosis fungoides, Kaposi's sarcoma etc, it need to treatment dose planning for total skin electron beam (TSEB) therapy. Appropriate treatment planning for TSEB therapy is needed to give homogeneous dose distribution throughout the entire skin surface. The energy of 6 MeV electron from the 18 MeV medical linear accelerator was adapted for superficial total skin electron beam therapy. The energy of the electron beam was reduced to 4.2 MeV by a $0.5\;cm\times90\;cm{\times}180\;cm$ acryl screen placed in a feet front of the patient. Six dual field beam was adapted for total skin irradiation to encompass the entire body surface from head to toe simultaneously. The patients were treated behind the acryl screen plate acted as a beam scatterer and contained a parallel-plate shallow ion chamber for dosimetry and beam monitoring. During treatment, the patient was placed in six different positions due to be homogeneous dose distribution for whole skin around the body. One treatment session delivered 400 cGy to the entire skin surface and patients were treated twice a week for eight consecutive weeks, which is equivalent to TDF value 57. instrumentation and techniques developed in determining the depth dose, dose distribution and bremsstrahlung dose are discussed.

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Oral Candidiasis (임상가를 위한 특집 2 - 구강 캔디다증)

  • Kim, Ok-Joon
    • The Journal of the Korean dental association
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    • v.48 no.5
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    • pp.355-364
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    • 2010
  • The frequency of mucosal and cutaneous fungal infection is increasing worldwide, which is due to the increase of immunocompromised patients. Candida albicans are the principal species associated with human oral mycosis and are known to be the most virulent among pathogenic Candida spp. In this review, oral candidiasis were classified and oral mucosal manifestations of candidiasis were filed. And its diagnosis and management would be reviewed briefly.