• Title/Summary/Keyword: muscles

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The Inhibitory Effect of Eupatilin on the Intestinal Contraction Induced by Carbachol

  • Je, Hyun-Dong;Lee, Jong-Min;La, Hyen-Oh
    • Biomolecules & Therapeutics
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    • v.18 no.4
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    • pp.442-447
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    • 2010
  • This study was conducted to determine whether treatment with the anti-inflammatory eupatilin influences intestinal smooth muscle contraction stimulated by carbachol and, if so, to investigate the related mechanism. Denuded ileal or colonic muscles from Sprague-Dawley rats were used for the study and measurements of isometric contractions were obtained using a computerized data acquisition system; this data was also combined with results from molecular experiments. Eupatilin from Artemisia asiatica Nakai significantly decreased carbachol-induced contractions in both ileal and colonic muscles. Interestingly, eupatilin decreased carbachol-induced phosphorylation of ERK1/2 more significantly than that of MYPT1 at Thr855 in ileal and colonic muscles. However, eupatilin significantly decreased phosphorylation of MYPT1 at Thr855, but only in ileal muscle. Therefore, thin filament regulation, including MEK inactivation and related phospho-ERK1/2 decrease, is mainly involved in the eupatilin-induced decrease of intestinal contraction induced by carbachol. In conclusion, this study provides the evidence and a possible related mechanism concerning the inhibitory effect of the flavonoid as an antispasmodic on the agonist-induced contractions in rat ileum and colonic muscles.

Analysis of Muscle Activation related to Postural Stability according to Different Frequency of Whole Body Vibration during Quiet Standing (중립 선 자세에서의 전신진동 주파수에 따른 자세 안정근의 근활성 분석)

  • Seo, Hye-Jung;Kim, Joong-Hwi
    • The Journal of Korean Physical Therapy
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    • v.25 no.5
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    • pp.316-321
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    • 2013
  • Purpose: The aimed of this study was to investigate muscle activation related to postural stability according to different frequency of whole body vibration during quiet standing, to identify the most effective training conditions that cause the highest neuromuscular responses, and to evaluate the difference of EMG activation according to the anatomical position of the muscle - proximal or distal from the vibration platform. Methods: Eighteen healthy subjects voluntarily participated in this single-group, repeated-measures study in which EMG data from upper trapezius, rectus abdominalis, external oblique abdominalis, elector spinae, gluteus maximus, rectus femoris, semitendinosus, and gastrocnemius were collected over different frequencies (0-5-10-15-20-25Hz) for each subject during quiet standing. Results: We observed a statistically significant difference in the mean values of %RVC of muscular activation according to different frequencies of whole body vibration during quiet standing in all muscles (p<0.05). Conclusion: Our results indicate that lower frequencies of vibration result in low muscular activation, and higher frequencies elicit high muscular activation. However, the most effective training condition that caused the highest activation was 20 Hz. In addition, the proximally located lower extremity muscles (GCM, RF, ST, GM) showed higher activation than the distally located trunk and neck muscles (ES, EO, RA, UT) together with increasing frequency.

The suggestion of Proper Pressure level in Cranio-Cervical Flexion Exercise for Deep Cervical Flexor by Ultrasonographic Measurement (초음파 영상을 통한 머리-목 굽힘 운동의 적정 수준 제시에 관한 연구)

  • Jun, Deok-Hoon;Fell, Dennis W.;Kim, Kyoung
    • Journal of the Korean Society of Physical Medicine
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    • v.6 no.4
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    • pp.497-504
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    • 2011
  • Purpose : Chronic cervical pain is a common source of disability in society. There has been no research regarding the amount of pressure for the deep cervical flexors during cranio-cervical flexion exercise (CCFE). The purpose of this study is to determine optimal pressure levels to facilitate deep cervical muscles (longus colli & longus capitis) during cranio-cervical flexion exercise, using ultrasound measurement of the muscles. Methods : Using a cross-sectional design, the study was performed in an experimental group of 19 subjects (7 men, 12 women) with no cervical pain. Participants were instructed to perform the CCFE, and during the five incremental stages of the test, changes in thickness, as compared to resting baseline values, were measured using ultrasonography for sternocleidomastoid muscle (SCM) and deep cervical muscles (DCF). Results : Both DCF and SCM muscles demonstrated an increase in recruitment with each progressive phase of the test. In comparing the different pressure increments, the most significant changes found in DCF thickness were between phase 2 and phase 3 (p<.05). However no differences were found between pressure increments for SCM thickness (p>.05). Conclusion : The results suggest 26 mm Hg as the optimal pressure level during cranio-cervical flexion exercise for facilitation of deep cervical flexor.

Effects of Isometric Upper Limb Contraction on Trunk and Leg Muscles During Sit-to-stand Activity in Healthy Elderly Females

  • Jang, Eun-Mi;Oh, Jae-Seop;Kim, Mi-Hyun
    • Journal of the Korean Society of Physical Medicine
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    • v.12 no.1
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    • pp.61-66
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    • 2017
  • PURPOSE: The purpose of this study was to investigate the effects of isometric upper limb contraction on the trunk and lower extremity muscles during the sit-to-stand activity in elderly females. METHODS: Eighteen healthy elderly females performed three directional isometric upper extremity contractions (flexion, extension, and horizontal abduction movements) using an elastic band during sit-to-stand activity. Electromyography signals were collected from the internal oblique, erector spinae, rectus femoris, and biceps femoris muscles. RESULTS: Internal oblique activity was greater in bilateral shoulder flexion and bilateral shoulder horizontal abduction than in neutral position (p<.05). Erector spinae and rectus femoris muscle activities in bilateral shoulder flexion was greater than in neutral position and bilateral shoulder extension (p<.05). Biceps femoris activity was significantly greater in bilateral shoulder flexion than in bilateral shoulder extension and horizontal abduction, and in neutral position compared to bilateral shoulder extension (p<.05). CONCLUSION: These results suggest that incorporating isometric upper limb contraction may be beneficial for enhancing the contribution of trunk and lower extremity muscle activities to trunk stabilization during sit-to-stand activity. Therefore, isometric upper limb contraction during sit-to-stand tasks, especially in flexion, may be used to elicit contraction of the lumbopelvic region muscles within a tolerable range, for developing endurance and strength in the elderly.

Effects of Sling Exercise using Neurac Technic on Shoulder Stabilization Muscles According to the Surface during Crawling Position (네발기기 자세에서 지지면에 따라 뉴렉기법을 적용한 슬링이 어깨 안정화 근육에 미치는 영향)

  • Chun, Hye-Lim;Kim, Kyung-Hun
    • Journal of Korean Physical Therapy Science
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    • v.25 no.2
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    • pp.24-34
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    • 2018
  • Purpose: The purpose of this study was to assess how much neurac technic affects the stability muscles of the shoulder according to the supporting surface in crawling position. Method: 29 healthy adult males participated in this experiment. The experiment consists of 2 experimental groups and 1 control group. It is conducted for 3 weeks. Each group exercised for 7 seconds and then rested for 3 seconds. Using EMG, the average value of serratus anterior, upper trapezius, and lower trapezius was repeated three times. Experimental group 1 conducted push up plus exercise applied neurac technic with sling on unstable supporting surface. Experimental group 2 conducted push up plus exercise applied neurac technic with sling on stable supporting surface. Control group conducted the push up plus exercise on stable supporting surface. One-way ANOVA was used for statistical analysis. Result: It was noticeable that the result of Experimental group 1 affects stability muscles of more than Experimental group 2 and Control group. Conclusion: Push up plus position applied neurac technic with sling on unstable supporting surface was the most effective in activating the stability muscles of the shoulder.

Localized Myositis Ossificans of the Temporal and Lateral Pterygoid Muscles- A Case Report for Open Limitation (측두근과 외측 익돌근에서 발생된 국한성 화골성 근염 : 개구제한을 주소로 내원한 환자의 증례보고)

  • Han, Won-Jeong
    • Journal of Oral Medicine and Pain
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    • v.37 no.4
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    • pp.227-231
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    • 2012
  • Localized myositis ossificans is a disease with the main feature of formation of heterotropic bone and fibrous tissue involving muscle. It also called traumatic myositis ossificans. Myositis ossificans is likely to occur in the femoral region or brachium but, rarely in the head and neck including the masticatory muscles. It arises from traumatic episodes caused by prolonged mouth opening, surgical procedure, local anesthesia injection. The main clinical feature is the mouth open limitation. The diagnosis of myositis ossificans is usually based on the patient's history, clinical symptoms and on imaging finding. We present the case of patient with localized myositis ossificans of the temporal and lateral pterygoid muscles.

The Comparison of Expert with Non-Expert EMG during Perform Back-round Kicking of Taekwondo (태권도 뒤후려차기 동작시 숙련자와 비숙련자의 근전도 비교)

  • Kim, Jae-Woo
    • The Journal of Korean Institute for Practical Engineering Education
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    • v.3 no.1
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    • pp.200-205
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    • 2011
  • This research is first to analyze an electomygram reaction of the lower limbs among the muscles used during a back-round kicking of Taekwondo, second to analyze the relationship between the muscles of the kicking limb and those of the supporting limb, third to compare EMG activity of expert with novice. Measured muscles are as follows; rectus fermoris which control flexion and stretching of femora and knee joints, vastus medialis and vastus lateralis, which control flexion and stretching of legs, and biceps fermoris, which control stretching of femora, bending of knee joints and abduction of the crus. The electomygram reaction of all these selected muscles were analyzed. Three kicks were performed, and electomygram of each of kicks were measured. Then, electomygram reaction of the best kick was used for electomygram analysis.

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Biological Differences between Hanwoo longissimus dorsi and semimembranosus Muscles in Collagen Synthesis of Fibroblasts

  • Subramaniyan, Sivakumar Allur;Hwang, Inho
    • Food Science of Animal Resources
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    • v.37 no.3
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    • pp.392-401
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    • 2017
  • Variations in physical toughness between muscles and animals are a function of growth rate and extend of collagen type I and III. The current study was designed to investigate the ability of growth rate, collagen concentration, collagen synthesizing and degrading genes on two different fibroblast cells derived from Hanwoo m. longissimus dorsi (LD) and semimembranosus (SM) muscles. Fibroblast cell survival time was determined for understanding about the characteristics of proliferation rate between the two fibroblasts. We examined the collagen concentration and protein expression of collagen type I and III between the two fibroblasts. The mRNA expression of collagen synthesis and collagen degrading genes to elucidate the molecular mechanisms on toughness and tenderness through collagen production between the two fibroblast cells. From our results the growth rate, collagen content and protein expression of collagen type I and III were significantly higher in SM than LD muscle fibroblast. The mRNA expressions of collagen synthesized genes were increased whereas the collagen degrading genes were decreased in SM than LD muscle. Results from confocal microscopical investigation showed increased fluorescence of collagen type I and III appearing stronger in SM than LD muscle fibroblast. These results implied that the locomotion muscle had higher fibroblast growth rate, leads to produce more collagen, and cause tougher than positional muscle. This in vitro study mirrored that background toughness of various muscles in live animal is likely associated with fibroblast growth pattern, collagen synthesis and its gene expression.

A Comparison of Various Exercises for Scapular Stabilization (견갑골 안정화를 위한 다양한 운동의 비교연구)

  • Kim, Myungjin;Lee, Yujin;Kim, Jihyuk;Bae, Wonsik
    • Journal of The Korean Society of Integrative Medicine
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    • v.1 no.3
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    • pp.51-62
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    • 2013
  • PURPOSE : This study of 20 healthy male subjects by applying various scapular stabilization exercise to compared Serratus anterior and lower trapezius is change in ultrasound images. METHOD : Thirty healthy subjects voluntarily participated in this study. Ultrasound imaging was recorded from the increasing the activity of Serratus anterior(SA) and Lower trapezius(LT) muscles using Push-up plus, Wall slide, Scapular plane shoulder elevation with resistance exercise. Thickness changes in the Serratus anterior(SA) and lower trapezius(LT) muscles between the relaxed and contracted states in the each exercises. To identify statistical significance, one-way ANOVA with repeated measures was used with the significance level of .05. RESULT : The results of this study were as follows : 1) There were statistically significant difference in thickness changes in the Serratus anterior(SA) and lower trapezius(LT) muscles between the relaxed and contracted states in the each exercises. 2) The Scapular plane shoulder elevation with resistance is more effective to Strengthening in the scapular stabilization muscles than Push up-plus and Wall slide. CONCLUSION : The Scapular plane shoulder elevation with resistance may be used to effectively that patient with various shoulder pain.

Factors Affecting the Inosine Monophosphate Content of Muscles in Taihe Silkies Chickens

  • Chen, G.H.;Li, H.F.;Wu, X.S.;Li, B.C.;Xie, K.Z.;Dai, G.J.;Chen, K.W.;Zhang, X.Y.;Wang, K.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.9
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    • pp.1359-1363
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    • 2002
  • In this paper, changes in the concentration of inosine monophosphate (IMP) of muscles in Taihe Silkies chickens from 2 to 28 weeks of age were studied. The results showed that: (1) with increasing age, IMP content of muscles decreased continuously. (2) the relationship between body weight and IMP content of musculus pectoralis major was significantly negative (p<0.01), so was body weight and IMP content of musculus peronaeus, and their coefficients of correlation were -0.45, -0.38 respectively; the relationship between IMP contents of musculus pectoralis major and that of musculus peronaeus was more significantly positive (p<0.01), and its coefficient of correlation was 0.59. (3) by multiple regression analysis, changes of IMP content of muscles depended on the weeks of age and body weight. (4) from 2 to 28 weeks of age, the heritabilities of IMP content of musculus pectoralis major were calculated between 0.33-0.48, and those of musculus peronaeus were calculated between 0.51-0.69.