• Journal of Korean Academy of Nursing
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• v.26 no.2
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• pp.271-280
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• 1996

The purpose of this study was to determine the effect of periodic walking during hindlimb suspension on the mass, relative weight, fiber type distribution and cross-sectional area of Type I and II fibers in the developing Type II plantaris muscle. To examine the effectiveness of periodic walking on mass and fiber size, the hindlimbs of young female Wistar rats were suspended (HS group) and half of these rats walked on a treadmill for 45 min／day(15 min every 4 hours) at 5 meters／min at a 15 degree grade(HS-W group) After seven days of hindlimb suspension, the plantaris muscle wet weight was 28.40％ significantly smaller（P＜0.005） and relative plantaris muscle weight was 26.97％ smaller compared with those of control rats（P＜0.05）. The plantaris muscle wet weight and the relative plantaris muscle weight increased by 46.60％ and 49.23％ respectively with periodic walking, moreover. the plantaris muscle wet weight and the relative plantaris muscle weight of the HS-W rats recovered to the level of the control rats. No change was observed in fiber type percentage of the developing plantaris muscle following one week of hindlimb suspension or periodic walking during hindlimb suspension. Type I and II fiber cross-sectional areas of the developing plantaris muscle were 42.51％ and 43. 68％ lower in the HS group than in the control group（p＜0.0001）, Type I and II fiber cross-sectional areas of the developing plantaris were 30.82％ and 45.97％ greater in the HS-W group than in the HS group（p＜0.0001）, whereas Type I and II fiber cross-sectional area of HS-W group were less than those of the control group（P＜0.0001） The results suggest that periodic walking can attenuate developing plantaris muscle atrophy induced by hindlimb suspension.

• Journal of Microbiology and Biotechnology
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• v.34 no.3
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• pp.495-505
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• 2024

Gromwell (Lithospermum erythrorhizon, LE) can mitigate obesity-induced skeletal muscle atrophy in C2C12 myotubes and high-fat diet (HFD)-induced obese mice. The purpose of this study was to investigate the anti-skeletal muscle atrophy effects of LE and the underlying molecular mechanism. C2C12 myotubes were pretreated with LE or shikonin, and active component of LE, for 24 h and then treated with 500 μM palmitic acid (PA) for an additional 24 h. Additionally, mice were fed a HFD for 8 weeks to induced obesity, and then fed either the same diet or a version containing 0.25% LE for 10 weeks. LE attenuated PA-induced myotubes atrophy in differentiated C2C12 myotubes. The supplementation of LE to obese mice significantly increased skeletal muscle weight, lean body mass, muscle strength, and exercise performance compared with those in the HFD group. LE supplementation not only suppressed obesity-induced skeletal muscle lipid accumulation, but also downregulated TNF-α and atrophic genes. LE increased protein synthesis in the skeletal muscle via the mTOR pathway. We observed LE induced increase of mitochondrial biogenesis and upregulation of oxidative phosphorylation related genes in the skeletal muscles. Furthermore, LE increased the expression of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha and the phosphorylation of adenosine monophosphate-activated protein kinase. Collectively, LE may be useful in ameliorating the detrimental effects of obesity-induced skeletal muscle atrophy through the increase of protein synthesis and mitochondrial biogenesis of skeletal muscle.

• Fisheries and Aquatic Sciences
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• v.4 no.4
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• pp.261-264
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• 2001

Seasonal variation in fatty acid profiles was examined in the visceral mass and the posterior adductor muscle of the female pen shell, Atrina pectinata. Total percentages of saturated fatty acids were similar between the two organs, and there was not a prominent seasonal change in both tissues. While the percentages of highly unsaturated fatty acids (HUFAs) in the visceral mass were higher than those in the posterior adductor muscle, monounsaturated fatty acids (MUFAs) were high in the posterior adductor muscle. HUFA contents, especially in $20: 5\omega3$, $22: 5\omega3$ and $22: 6\omega3$, markedly decreased in September in the visceral mass, and this decrease was associated with a corresponding total MUFAs in the same organ. A similar pattern of change in September was noted in the posterior adductor muscle MUFAs and HUFAs. These results indicate that $20:\omega3$ and $22:\omega3$ HUFA changes in the visceral mass and posterior adductor muscle reflect the reproductive stages in pen shell.

• Journal of Korean Academy of Nursing
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• v.36 no.1
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• pp.5-14
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• 2006

Purpose: This study was done to analyze the effects of an exercise program on body composition and physical fitness of obese female college students. Method: Data was collected from September 29, 2003 to December, 29, 2003. The research design was arandomized control group pretest-posttest experimental design. The subjects were college nursing students at K University. Forty four students, 20 in the experimental group and 24 ina control group, with more than $30\%$ body fat were randomly assigned. The subjects in the experimental group participated in an exercise program for 12 weeks, sixty minutes per session, five times per week. Body composition and physical fitness was measured by a body composition analyzer, cardiovascular endurance, muscle endurance, muscle strength(grip strength, back strength), flexibility, balance, agility(whole body reaction time) and power(standing long jump). Result: Body weight(F=4.76, p=0.035), body fat(kg)(F=5.68, p=0.022) and body mass index(F=5.73, p=0.021) of the experimental group were significantly different from the control group, but there were no significant differences in body fat($\%$), lean body mass, muscle mass and WHR. Back strength(F=6.50, p=0.015), flexibility(F=14.62, p=0.000), muscle endurance(F=7.98, p=0.007), power(F=5.76, p=0.02l) and balance(F=2.46, p=0.018) of the experimental group were significantly different from the control group, but there were no significant differences in cardiovascular endurance, grip strength or agility. Conclusiton: The exercise program was effective in improving body weight, body fat(kg), body mass index, back strength, muscle endurance, flexibility, balance and power of obese female college students.

• Korean Journal of Applied Biomechanics
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• v.22 no.2
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• pp.219-228
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• 2012

The purpose of this study was to investigate how induced fatigue of the ankle joint muscles affects the capability and recovery of postural control during single-leg stance in healthy adults. The study population included 22 randomly recruited men and women. Postural control was performed on single-leg stance with eyes open. Ankle joint muscle was fatigued by repeated heel raises. According to the results of this study, for the anteroposterior variables, both men and women showed significantly increased center of mass velocity and decreased center of pressure 95% edge frequency immediately after fatigue. For the mediolateral variables, both men and women showed significantly increased center of mass velocity and decreased center of pressure 95% edge frequency immediately after fatigue. For the total variables, both men and women showed significantly increased center of mass averaged-velocity immediately after fatigue, and also, the center of pressure 95% confidence ellipse area significantly increased in women. Postural control variables were not significantly different for men and women at any time (Pre, P0, P10, and P20). In conclusion, the gender does not affect the capability and recovery after induced fatigue of ankle joint muscles. The effect of fatigue found for the anteroposterior and the mediolateral variables in both men and women. Furthermore ankle joint muscle fatigue led to change of postural control strategy from an ankle joint strategy towards a hip joint strategy. These changes are believed to damage postural control. The ankle joint muscle recovered from fatigue within 20 min during single-leg stance.

• PNF and Movement
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• v.19 no.3
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• pp.331-340
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• 2021

Purpose: The purpose of this study was to investigate the differences in body composition, upper and lower limb muscle strength, and functional physical ability in urban-dwelling elderly women with or without obesity. Methods: All study participants were assigned to the normal weight group (n=8, BMI<25) and the obesity group (n=7, BMI>25) based on their obesity rate. Anthropometric measurement was conducted and body composition was measured. For the upper and lower limb strength, grip strength and maximal isometric knee extension and flexion were evaluated by a dynamometer. The senior fitness test was performed to measure functional ability. Data analysis was conducted by the independent t-test and the alpha level was set at 0.05. Results: The waist, hips, and thighs of obese elderly women were thicker than those of normal-weight elderly women. This physical difference resulted from body fat mass, not muscle mass. Despite a similar level of limb muscle mass between the two groups, the upper limb grip strength was higher (24.00% for left, 19.95% for right) in the normal-weight women than the obese women (p<0.05), but otherwise there was no difference in maximal knee flexion or extension isometric strength. Functional physical ability showed no difference in a 30-second chair sit and stand test and a six-minute walk test, but a 30-second arm-curl (11.00% for left, 14.81% for right), back stretch (8.54cm for left, 8.99cm for right), chair sit and reach (9.22cm for left, 6.24cm for right), and 2.44 meter round trip walk (0.62 sec, 9.39%) were faster in performance for normal-weight elderly women than obese elderly women (p<0.05). Conclusion: Taken together, despite similar levels of upper and lower extremity muscle mass, normal-weight elderly women showed higher performance in upper limb strength, flexibility, and agility than obese elderly women, but there was no difference in lower extremity functional muscle strength and cardiopulmonary endurance.

• Food Engineering Progress
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• v.22 no.4
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• pp.358-365
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• 2018

Whole grain cereal (WGC)-rich diets provide macronutrients that are important for the regulation of energy metabolism. The current study evaluated whether WGCs had a preventive effect on sarcopenic obesity in high-fat diet (HFD)-induced obese mice. C57BL/6N mice were fed a normal diet (ND), ND+WGC, HFD, and HFD+WGC for 12 weeks. WGCs significantly reduced body weight gain, food efficiency ratio, fat mass, and adipocyte size in HFD-induced obese mice. WGCs attenuated HFD-induced nonalcoholic fatty liver disease by decreasing liver weight and hepatic fat accumulation. In addition, WGCs increased muscle strength and muscle mass in HFD-induced obese mice as well as in ND mice. Taken together, WGCs can be employed as functional food materials for the prevention of sarcopenic obesity by inhibiting fat accumulation and increasing muscle mass.

• The Korean Journal of Physiology and Pharmacology
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• v.19 no.3
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• pp.191-196
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• 2015

Attenuated functional exercise capacity in elderly and diseased populations is a common problem, and stems primarily from physical inactivity. Decreased function and exercise capacity can be restored by maintaining muscular strength and mass, which are key factors in an independent and healthy life. Resistance exercise has been used to prevent muscle loss and improve muscular strength and mass. However, the intensities necessary for traditional resistance training to increase muscular strength and mass may be contraindicated for some at risk populations, such as diseased populations and the elderly. Therefore, an alternative exercise modality is required. Recently, blood flow restriction (BFR) with low intensity resistance exercise (LIRE) has been used for such special populations to improve their function and exercise capacity. Although BFR+LIRE has been intensively studied for a decade, a comprehensive review detailing the effects of BFR+LIRE on both skeletal muscle and vascular function is not available. Therefore, the purpose of this review is to discuss previous studies documenting the effects of BFR+LIRE on hormonal and transcriptional factors in muscle hypertrophy and vascular function, including changes in hemodynamics, and endothelial function.

• Journal of Environmental Science International
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• v.1 no.1
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• pp.23-27
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• 1992

The changes of pectoral muscle size (as an index of protein reserves) and fat reserves (as an index of lipid) were measured in wintering Dunlin during 1988 -1989 on two estuaries located in the south coast of Korea. The mean of lean mass of February population was greater(11.8%) than that of October population. SMI of October population was greater(4.5%) than that of February population and lipid index of October population also greater(1.6%) than that of February population. This show that the body condition of October population is better than February population. The mean of fat and protein reserves of 22 % of Dunlin arriving on October for their wintering were higher than that of others, this group seems to continue their migration to south further and 11% of the wintering population seems to starve during winter.

• Journal of Nutrition and Health
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• v.39 no.7
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• pp.617-623
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• 2006

The mortality and morbidity rate of hemodialysis patients (HD) remain high. Among many factors, protein and calorie malnutrition has been shown to be a major risk factor for increased mortality in the HD patients population. Malnutrition can be caused by insufficient amino acid intake, nutrient losses in dialysate, oxidant stress and muscle catabolism. In this study, we evaluated the association of markers of nutritional status and essential amino acids intake in HD patients. We investigated nutritional status of 41 HD patients (mean age: $64.2\;{\pm}\;11.5\;y$, men: 24, women: 27) by measuring anthropometric, biochemical parameters and food intakes by using 24 hr recall methods. Subject's total energy intake and total protein intake were $1,648.0\;{\pm}\;397.31\;kcal/day,\;79.2\;{\pm}\;27.2\;g/day$:, respectively. The animal protein intake was $42.7\;{\pm}\;22.1\;g/day$, essential amino acids intake was $23.4\;{\pm}\;9.92\;g/day$, and the ratio of essential amino acids to total protein intake was $29.6\;{\pm}\;5.42%$. There were significantly positive correlation between muscle mass and lean body mass with serum creatinine level (r=0.435, p<0.01; r=0.435, p<0,01). There were also significant positive correlation in muscle mass and lean body mass with pre hemodialysis blood urea nitrogen (preHD BUN) (r=0.329, p<0.05; r=0.329, p<0.05). There were no significant correlation in total energy intake and total protein intake per kg ideal body weight (IBW) to muscle mass and lean body mass. However, there were significantly positive correlation between the ratio of essential amino acids and muscle mass and lean body mass (r=0.368, p<0.05; r=0.405, p<0.01). And serum hematocrit concentration was positively correlated with the ratio of essential amino acids (r=0.032, p<0.05). The results of this study indicate that strong associations exist in essential amino acid intakes with malnutrition than total protein intakes in HD patient. In conclusion, specialized nutrition education should be necessary to efficiently improve the quality of protein intakes.