• Journal of Chest Surgery
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• 제30권1호
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• pp.48-54
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• 1997

본 인제대학교 의과대학 흉부외과학교실 서울백병 원에서는 1986년 10월부터 1995년 12월까지 부식제 의 음용으로 하인두와 식도 입구부터 심한 협착이 발생한 1 1례의 환자에서 하인두의 양배꼴동에 대용식 도를 문합하는 식도재건술을 시행하였다. 환자는 남자 7례, 여자 4례로 모두가 성인으로 연령은 21세 에서 47세까지로 평균 34세였다. 식도협착의 원인이 된 부식제는 산성이 6례: 알칼리성이 5례였다. 이들의 부식제 음용 동기는 자살 목적이 9례였 고, 사고로 인한 경우가 2례였다. 부식제의 음용후 최종적으로 식도재건술까지의 기간은 4개월에서 부 터 21년까지 였다. 식도재 건술시 이용한 대용식도는 9례에서는 우측 결장을 사용하였고, 2례는 이 전에 우측 결장을 이용한 식도재건술이 실패한 상태여서 좌측 결장을 사용하였다. 모든 환자에서 식도 절제술은 하지 않았고 결장은 흉골하로 거상하였다. 경부 문합은 환자의 머리를 똑바로 놓은 상태에서 경부에 J형태로 피부를 절개하고 흉골설골, 갑상설 골근을 절단하고 갑상연골의 연골막을 박리하여 감상연골을 역삼각형모양으로 부분절제하고 양배꼴동을 열고 결장과 단단문합하였다. 수술 직후 類觀隙\ulcorner환자는 음식물을 삼킬 때 연하곤란과 기도내로 음식물이 넘어가 고형 음식물로 삼키는 훈련이 필요하였다. 수술 후 발생한 합병증은 대용식도의 괴사가 3례가 발생하여 유리공장을 이식하였다. 3례에서는 경부 문합부위에 협착이 있어 2례에서 상부문합부위를 확장하였고 1례에서는 유착띠제거술을 시행하였으며 모두 협착이 해소되었다. 수술 후 외래 추적관찰에서 10례에서는 정상적으 로 음식물을 삼킬 수 있었고 유리공장을 사용하여 2차수술을 시행한 1례는 유리공장의 괴사로 3차수술 을 기다리고 있다.

• 한국운동역학회지
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• 제26권1호
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• pp.11-20
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• 2016

Objective: This study aimed to compare biomechanical data between elite and beginner cyclists during cycle pedaling by performing a comparative analysis and to provide quantitative data for both pedaling performance enhancement and injury prevention. Methods: The subjects of this study included 5 elite cyclists (age: $18{\pm}0years$, body mass: $64.8{\pm}9.52kg$, height: $173.0{\pm}4.80cm$) and 5 amateur cyclists (age: $20{\pm}0years$, mass: $66.6{\pm}2.36kg$, height: $175.6{\pm}1.95cm$). The subjects pedaled on a stationary bicycle mounted on rollers of the same gear (front: 50 T and rear: 17 T = 2.94) and cadence of 90. The saddle height was adjusted to fit the body of each subject, and all the subjects wore shoes with cleats. In order to obtain kinematic data, 4 cameras (GR-HD1KR, JVC, Japan) were installed and set at 60 frames/sec. An electromyography (EMG) system (Telemyo 2400T, Noraxon, USA) was used to measure muscle activation. Eight sets of data from both the left and right lower extremities were obtained from 4 muscles (vastus medialis oblique [VMO], vastus lateralis oblique [VLO], and semitendinosus [Semitend], and lateral gastrocnemius [Gastro]) bilaterally by using a sampling frequency of 1,500 Hz. Five sets of events ($0^{\circ}$, $90^{\circ}$, $180^{\circ}$, $270^{\circ}$, and $360^{\circ}$) and 4 phases (P1, P2, P3, and P4) were set up for the data analysis. Imaging data were analyzed for kinematic factors by using the Kwon3D XP computer software (Visol, Korea). MyoResearch XP Master Edition (Noraxon) was used for filtering and processing EMG signals. Results: The angular velocity at $360^{\circ}$ from the feet was higher in the amateur cyclists, but accelerations at $90^{\circ}$ and $180^{\circ}$ were higher in the elite cyclists. The amateur cyclists had greater joint angles at $270^{\circ}$ from the ankle and wider knee joint distance at $0^{\circ}$, $180^{\circ}$, and $360^{\circ}$ than the elite cyclists. The EMG measurements showed significant differences between P2 and P4 from both the right VLO and Semitend. Conclusion: This study showed that lower body movements appeared to be different according to the level of cycle pedaling experience. This finding may be used to improve pedaling performance and prevent injuries among cyclists.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제32권2호
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• pp.81-93
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• 2006

Obstructive sialadenitis is one of common disease in salivary gland, and most common histologic features are loss of acinar cell and ductal dilatation associated with fibrosis, and infiltration of inflammatory cells. Although many experimental studies has been accomplished for the salivary acinar cell change in obstructive salivary gland disease, studies for myoepithelial cell were deficient. This study is designed for salivary gland tissue change, especially myoepithelial cell when nonspecific chronic sialadenitis or salivary duct injury by duct obstruction or cut can be occurred that is common encounted clinically. After ligation and cutting of submandibular gland of rabbit, groups of aminmal were sacrificed at 1, 2, 4 weeks postoperatively, submandibular gland were removed. The histopathologic evaluation was done with light microscopy. And, with immunohistochemical staining with ${\alpha}$-smooth muscle actin, characteristics of myoepithelial cell were examined. With transmission electron microscopy, ultrastructure of myoepithelial cell were examined for distribution and ultrastructure of myoepithelial cell. The results were obtained as follows: 1. In the histopathologic evaluation, ligation and cutting group of 1 week, linkage of myoepithelial cell associated with acinar atrophy and degeneration were disappeared in both group. 2. More prominent squamous metaplasia was seen in acinar cells of ligation group of 2 weeks experimental rabbit than cutting group. 3. Acinar cells are nearly disappeared in both ligation and cutting group of 4 weeks, and myoepithelial cell also disappeared associated with acinar cell atrophy, and duct-like structure composed by squamous cells by squamous metaplasia in acinar cells were distributed. 4. In immunohistochemical study, both ligation and cutting group ${\alpha}$-SMA distribution were diminished at 1 week experimental rabbits, but myoepithelial cell was more diminished in ligation group than cutting group, which were distributed around cells of squamous metaplasia. 5. Nuclear condensation, chromosome margination, and cytoplasmic vaculoation were appeared in myoepithelial cell of both cutting and ligation group after 1 week with transmission electron microscopy. But degenerative substance were seen in cytoplasm of myoepithelial cell of ligation group of 4 weeks. From the results obtained in this study, atrophy and degeneration of myoepithelial cell was more prominent in duct ligation group than duct cutting group, and myoepithelial cells were seen around cells squamous metaplasia of acinar cell.

• 혜화의학회지
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• 제10권1호
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• pp.395-415
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• 2001

A general concept of Geun includes the soft organizations such as a muscle, a myofascia, a tendon and a ligament, cartilages and nerves that surround it. The main function of it is a movement of the body such as a flextion and a extension, a connection of the joints, and a construction of the body shape. Lately, we consider Geun important little by little, develop a variety of the therapeutic measures which make use of it, and apply it to the treatment in the oriental medicine, And the therapeutic measures which utilize Geun will be developed from now on. Therefore, this study reviewed and analyzed the direction of the research referred to Geun in the oriental medicine and the tendency to the experiment to grow the study referred to Geun in oriental medicine continuously and developed the new direction. This study collected 44's theses reported in the oriental medical journal and analyzed in accordance with the journal, time, form and topics. The following results were obtained in this study; 1. In the theses referred to Geun, the journal of Korean acupuncture & moxibustion society and of Korean oriental medicine have the most of them(11's theses) and at the next the journal of oriental rehabilitation medicine has 9's theses. 2. By analyzing the form of the theses, these were classified into the theoretical, experimental and clinical studies. The theoretical these occupied 39%, the experimental theses 54%, and the clinical theses 7%. 3. By analyzing the theses referred to Geun, these were classified into the muscular abnormality - such as a powerlessness, a injury, a atrophy, a disorder, and a pain - the theory of muscles along the regular meridians, the muscular organization, the therapeutic measures, the manipulation and so on. 4. The theses of the muscular abnormality occupied 30% of them referred to Geun and the theory of muscles along the regular meridians 20%, the muscular organization 12%, the therapeutic measures 12%, and the manipulation 8%. According to the above results, the study of the new field referred to Geun and the clinical report are indispensable since the field is limited and the tendency is theoretical and experimental.

• The Journal of Korean Physical Therapy
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• 제12권2호
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• pp.255-265
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• 2000

정상적인 골 조직에서의 성장과는 달리 연부조직에 2차적으로 비정상적인 골 조직이 신생되면서 골화되는 현상을 골화성 근염 또는 화골성 근염이라고 하며, 연부조직에 생긴 골은 가장 안쪽에는 어떤 원인에 의해서 생긴 출혈 또는 괴사 조직의 주위를 섬유모세포가 둘러싸서 생긴 층이 있고, 그 다음으로 골모세포(osteoblasts)로 형성된 미성숙 골조직 충이 있으며, 마지막 주위의 결합조직과 명확한 경계를 이루는 성숙한 골 소주로 구성된 층이 있다. 골화성 근염은 그 원인이 정확히 밝혀지지 않았으나. 혈류의 정체로 인한 저산소증, 비정상적인 칼슘 대사, 미세한 외상의 반복 및 심한 외상, 장기간 고정, 유전적인 원인 등으로 각기 다른 양상의 골화성 근염을 형성할 수 있다. 골화성 근염이라는 단어는 1868년에 Von Dusch에 의해 처음 사용되어 명확한 구분 없이 연부조직에 생긴 비정상 골조직을 일컫는 말로 사용되어져 왔다. 하지만 골화성 근염이라 할지라도 발생 원인과 조직 변화 및 상태 등을 고려한다면 첫째로 선천성 기형과 전신이환을 동반하는 진행성 골화성 근염, 둘째로 신경근과 만성질병, 사지마비, 소아마비, 화상. 다발성 관염 . 파상풍을 가진 환자에게서 발생하는 골화성 근염인 이소성 골화증, 새 번째로 연부조직의 심한 손상 또는 반복적인 손상, 골절, 탈구, 열상 외과적 절개에 대한 부차적인 반응으로 나타나는 외상성 골화성 근염. 네 번째로 위의 세 가지 원인이 아닌 원인으로 발생하는 비외상성 골화성 근염으로 분명히 구분할 수 있다. 때문에 단순히 골화성 근염이란 단어로 연부조직에 생긴 비정상적인 골을 통칭하기보다는 지금까지 언급한 내용을 고려해 보다 구체적인 질환명 즉 골화성 근염이 진행성인지. 이소성인지. 외상성인지. 비외상성인지를 명확히 구분하여 사용하는 것이 바람직하다.

• Journal of Korean Neurosurgical Society
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• 제56권3호
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• pp.218-223
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• 2014

Objective : C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are often utilized to evaluate for postoperative infection. Abnormal values may be detected after surgery even in case of non-infection because of muscle injury, transfusion, which disturbed prompt perioperative management. The purpose of this study was to evaluate and compare the perioperative CRP, ESR, and white blood cell (WBC) counts after spine surgery, which was proved to be non-infection. Methods : Twenty patients of lumbar open discectomy (LOD) and 20 patients of posterior lumbar interbody fusion (PLIF) were enrolled in this study. Preoperative and postoperative prophylactic antibiotics were administered routinely for 7 days. Blood samples were obtained one day before surgery and postoperative day (POD) 1, POD3, and POD7. Using repeated measures ANOVA, changes in effect measures over time and between groups over time were assessed. All data analysis was conducted using SAS v.9.1. Results : Changes in CRP, within treatment groups over time and between treatment groups over time were both statistically significant F(3,120)=5.05, p=0.003 and F(1,39)=7.46, p=0.01, respectively. Most dramatic changes were decreases in the LOD group on POD3 and POD7. Changes in ESR, within treatment groups over time and between treatment groups over time were also found to be statistically significant, F(3,120)=6.67, p=0.0003 and F(1,39)=3.99, p=0.01, respectively. Changes in WBC values also were be statistically significant within groups over time, F(3,120)=40.52, p<0.001, however, no significant difference was found in between groups WBC levels over time, F(1,39)=0.02, p=0.89. Conclusion : We found that, dramatic decrease of CRP was detected on POD3 and POD7 in LOD group of non-infection and dramatic increase of ESR on POD3 and POD7 in PLIF group of non-infection. We also assumed that CRP would be more effective and sensitive parameter especially in LOD than PLIF for early detection of infectious complications. Awareness of the typical pattern of CRP, ESR, and WBC may help to evaluate the early postoperative course.

• 한국수산과학회지
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• 제32권5호
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• pp.593-600
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• 1999

우리나라 전 연안의 조간대에 분포하고 있는 총알고둥을 대상으로 생존, 성장, 호흡, 배설에 미치는 유기주석, 수은 및 카드뮴의 만성저해성 연구를 통하여, 오염으로 인한 독성과 그에 따른 내성등을 생물학적 방법을 이용하여 조사하였다. 수온 $23^{\circ}C$에서 80일 동안 TBTCl, Hg 및 Cd의 각 실험농도에 폭로시킨 총알고둥의 생존율은 TBTCl, 0.9$\mu$g/$\ell$에서 $80\%$, Hg, 200$\mu$g/$\ell$에서 $25\%$, 그리고 Cd, 100$\mu$g/$\ell$에서는 $45\%$였다. 각 실험농도에 폭로된 총알고둥의 일일 평균 성장률은 대조구에서 0.023mm/day였으며, TBTCl의 경우는 0.1 $\mu$g/$\ell$에서 0.019mm/day로 $17.39\%$, 0.9 $\mu$g/$\ell$에서는 0.014 mm/day로 $39.13\%$ 감소하였으며, Hg의 경우는 50 $\mu$g/$\ell$에서 0.015 mm/day로 $34.78\%$, 200 $\mu$g/$\ell$에서는 0.008mm/day으로 $65.22\%$ 감소하였다. 그리고 Cd의 경우는 5$\mu$g/$\ell$에서 0.017 mm/day로 $26.09\%$, 100 $\mu$g/$\ell$에서는 0.008 mm/day으로 $65.22\%$ 감소하였다. TBTCl, Hg 그리고 Cd의 각 저해농도에 폭로시킨 총알고둥의 호흡 및 질소 배설률은 폭로시간의 경과에 따라 대체로 폭로전반에는 감소하다가 다시 증가하는 경향을 보였다. 각 오염원에 따른 조직학적 변화양상은 TBTCl에서 아가미, Hg에서는 소화관 그리고 Cd의 경우에는 발 근육층부분에서 가장 크게 나타났다.

• 한국융합학회논문지
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• 제12권4호
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• pp.303-310
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• 2021

본 연구는 원위경비인대결합이 손상된(High Ankle Sprain) 운동선수들의 경·비간 압박테이핑 적용이 통증, 관절가동범위, 근력에 미치는 영향을 규명하는데 있다. High Ankle Sprain 또는 발목 염좌를 진단받은 선수 중 이학적 검사결과 양성인 운동선수 14명을 대상으로 중도 포기 4명을 제와한 10명을 대상으로 진행하였다. 3주간 아급성기재활 전, 중, 후로 경비간 압박테이핑 처치군(TG)과 적용하지 않는 대조군(NTG)으로 나누어 통증, 관절가동범위, 등척성근력을 측정 하였다. 통계는 반복측정에 의한 변량분석을 실시하였으며 사후검증은 t-test를 실시하였다. 연구 결과 통증(VAS)은 유의한 차이가 발생하지 않았으며, 관절가동범위는 두 그룹 모두 내번과 외번 가동범위가 시기간 유의한 증가를 보였고, 등척성근력은 테이핑 처치군 에서만 내번(0°, 7°, 14°)과 외번(0°)에서 시기간 유의한 향상이 나타났다. 결론적으로 원위경비인대결합 손상 운동선수의 경·비간 압박 테이핑 적용이 아급성기 재활프로그램에서 동일한 통증수준에서도 관절가동범위와 근력의 조기 향상에 효과가 있는 것으로 나타났다.

• 대한물리치료과학회지
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• 제28권2호
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• pp.57-64
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• 2021

Background: During squat exercises, Ankle joint stability during squat movement transfers forces produced by unstable supports or various loads to the leg joints and trunk, reducing the risk of injury; therefore, a reference is needed for correct ankle joint posture during squat exercises. The purpose of this study was to examine the effect of ankle joint stability on quadriceps femoris and hamstring activation during squat exercises. Design: Quasi-experiment one group pretest-posttest design. Methods: The participants in this study were 20 volunteers who performed squat exercises with and without kinesiology tape. We measured quadriceps femoris and hamstring activation using surface electromyography. The ankle joint was stabilized with kinesiology tape using the ankle balance taping (ABT) method. A paired t-test was performed to compare differences between taping conditions. Results: Vastus medialis and vastus lateralis activation were greater following squat exercises with kinesiology tape than without; however, the difference was not significant. Medial and lateral hamstring activation was not significantly different between taping conditions. Conclusion: Although it is difficult to maintain stability using kinesiology tape alone, ankle joint stability is believed to affect quadriceps femoris muscle activity, which increases the effectiveness of the squat exercise.

• 한국임상수의학회지
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• 제40권2호
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• pp.93-103
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• 2023

The tendon is a dense connective tissue that connects muscle to bone and plays an essential role in joint motion. The injured tendon heals slowly owing to its low cellularity and vascularity. This study aimed to evaluate and compare the effects of regenerative injection therapy (RIT), 20 % dextrose prolotherapy (DP), and platelet-rich plasma (PRP) injections that can promote tendon healing. Twenty-one New Zealand white rabbits were divided into the control, DP, and PRP treatment groups. The superficial digital flexor tendon (SDFT) of the right hindlimb of each rabbit was used. A round defect of 2 mm was induced. Approximately 0.2 mL of 20% dextrose and autologous PRP were injected into the proximal and distal ends of the SDFT mass. Radiographic and ultrasonographic examination and cross-sectional area (CSA) calculations were performed pre-operatively and at 2, 4, and 8 weeks. The SDFT of both limbs was transected for biomechanical and histomorphometric evaluations. The SDFT of the left limb was transected for intact control. Semi-quantitative analysis was performed to evaluate the histomorphometric properties. Additional analysis was performed using H&E, Masson's trichrome, and immunohistochemical staining. The biomechanical evaluation showed that the treatment groups had higher tensile strength compared to the defect control group, while the PRP group had higher tensile strength than the DP group. On histological examination, the treatment groups appeared to be relatively closer to the remodeling phase of the healing process than the defect control group; the characteristics of the PRP group were closer to the remodeling phase than those of the DP group. The ultrasonographic examination showed different tendencies. Increased values in the CSA were observed during the early period in the treatment groups. This study suggests that PRP and DP can promote the healing of tendon injury, and these effects were superior with PRP than that with DP.